DE102016107563A1 - Vitaminzubereitung - Google Patents
Vitaminzubereitung Download PDFInfo
- Publication number
- DE102016107563A1 DE102016107563A1 DE102016107563.9A DE102016107563A DE102016107563A1 DE 102016107563 A1 DE102016107563 A1 DE 102016107563A1 DE 102016107563 A DE102016107563 A DE 102016107563A DE 102016107563 A1 DE102016107563 A1 DE 102016107563A1
- Authority
- DE
- Germany
- Prior art keywords
- vitamin
- preparation
- preparation according
- vitamin preparation
- poloxamer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 238000002360 preparation method Methods 0.000 title claims abstract description 39
- 229940088594 vitamin Drugs 0.000 title claims abstract description 28
- 229930003231 vitamin Natural products 0.000 title claims abstract description 28
- 235000013343 vitamin Nutrition 0.000 title claims abstract description 28
- 239000011782 vitamin Substances 0.000 title claims abstract description 28
- 150000003722 vitamin derivatives Chemical class 0.000 title claims abstract description 28
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 claims abstract description 21
- 229930003779 Vitamin B12 Natural products 0.000 claims abstract description 20
- 229920001983 poloxamer Polymers 0.000 claims abstract description 20
- 235000019163 vitamin B12 Nutrition 0.000 claims abstract description 20
- 239000011715 vitamin B12 Substances 0.000 claims abstract description 20
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 claims abstract description 16
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- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 14
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 12
- VAZJLPXFVQHDFB-UHFFFAOYSA-N 1-(diaminomethylidene)-2-hexylguanidine Polymers CCCCCCN=C(N)N=C(N)N VAZJLPXFVQHDFB-UHFFFAOYSA-N 0.000 claims description 10
- 229920002413 Polyhexanide Polymers 0.000 claims description 10
- 229940093158 polyhexanide Drugs 0.000 claims description 8
- 230000003139 buffering effect Effects 0.000 claims description 6
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- 239000002243 precursor Substances 0.000 claims description 5
- OAJLVMGLJZXSGX-SLAFOUTOSA-L (2s,3s,4r,5r)-2-(6-aminopurin-9-yl)-5-methanidyloxolane-3,4-diol;cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7 Chemical compound [Co+3].O[C@H]1[C@@H](O)[C@@H]([CH2-])O[C@@H]1N1C2=NC=NC(N)=C2N=C1.[N-]([C@@H]1[C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O OAJLVMGLJZXSGX-SLAFOUTOSA-L 0.000 claims description 4
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- 235000004866 D-panthenol Nutrition 0.000 description 3
- 239000011703 D-panthenol Substances 0.000 description 3
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 description 3
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- XDOFQFKRPWOURC-UHFFFAOYSA-N 16-methylheptadecanoic acid Chemical compound CC(C)CCCCCCCCCCCCCCC(O)=O XDOFQFKRPWOURC-UHFFFAOYSA-N 0.000 description 2
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- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 239000003883 ointment base Substances 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 235000021313 oleic acid Nutrition 0.000 description 1
- 229940055726 pantothenic acid Drugs 0.000 description 1
- 235000019161 pantothenic acid Nutrition 0.000 description 1
- 239000011713 pantothenic acid Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 229920001993 poloxamer 188 Polymers 0.000 description 1
- 229940044519 poloxamer 188 Drugs 0.000 description 1
- 229940068918 polyethylene glycol 400 Drugs 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 239000002453 shampoo Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- JNYAEWCLZODPBN-CTQIIAAMSA-N sorbitan Polymers OCC(O)C1OCC(O)[C@@H]1O JNYAEWCLZODPBN-CTQIIAAMSA-N 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 235000019871 vegetable fat Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 235000019156 vitamin B Nutrition 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
- 235000009492 vitamin B5 Nutrition 0.000 description 1
- 239000011675 vitamin B5 Substances 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- 150000003751 zinc Chemical class 0.000 description 1
Classifications
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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- A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Otolaryngology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102016107563.9A DE102016107563A1 (de) | 2016-04-22 | 2016-04-22 | Vitaminzubereitung |
| RU2018140968A RU2018140968A (ru) | 2016-04-22 | 2017-04-21 | Витаминный препарат |
| JP2018555119A JP7344641B2 (ja) | 2016-04-22 | 2017-04-21 | ビタミン製剤 |
| CN201780025027.8A CN109195586A (zh) | 2016-04-22 | 2017-04-21 | 维生素制剂 |
| US16/094,659 US20190111139A1 (en) | 2016-04-22 | 2017-04-21 | Vitamin preparation |
| EP17724319.3A EP3445333A1 (de) | 2016-04-22 | 2017-04-21 | Vitaminzubereitung |
| PCT/EP2017/059496 WO2017182619A1 (de) | 2016-04-22 | 2017-04-21 | Vitaminzubereitung |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102016107563.9A DE102016107563A1 (de) | 2016-04-22 | 2016-04-22 | Vitaminzubereitung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE102016107563A1 true DE102016107563A1 (de) | 2017-10-26 |
Family
ID=58737548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE102016107563.9A Pending DE102016107563A1 (de) | 2016-04-22 | 2016-04-22 | Vitaminzubereitung |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20190111139A1 (https=) |
| EP (1) | EP3445333A1 (https=) |
| JP (1) | JP7344641B2 (https=) |
| CN (1) | CN109195586A (https=) |
| DE (1) | DE102016107563A1 (https=) |
| RU (1) | RU2018140968A (https=) |
| WO (1) | WO2017182619A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2023169439A1 (zh) * | 2022-03-07 | 2023-09-14 | 上海云晟研新生物科技有限公司 | 一种维生素ad口溶膜组合物、其制备方法及应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014016277A2 (de) | 2012-07-24 | 2014-01-30 | Azoba Health Care Ag | Vitaminzubereitung |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5098691A (en) * | 1991-05-06 | 1992-03-24 | Colgate-Palmolive Company | Composition for disclosing dental plaque |
| JPH11189548A (ja) * | 1997-12-25 | 1999-07-13 | Toshio Sato | 無晶性医薬組成物及びその製造方法 |
| US20050196434A1 (en) * | 2004-03-04 | 2005-09-08 | Brierre Barbara T. | Pharmaceutical composition and method for the transdermal delivery of magnesium |
| DE102005001113A1 (de) * | 2005-01-08 | 2006-07-20 | Regeneratio Pharma Gmbh | Verwendung von Metallkomplexen von Tetrapyrrollheterocyclen zur Behandlung von entzündlichen Magen/Darmerkrankungen |
| CN101103985A (zh) * | 2006-07-14 | 2008-01-16 | 北京华安佛医药研究中心有限公司 | 叶酸滴丸及其制备方法 |
| US8940326B2 (en) * | 2007-03-19 | 2015-01-27 | Vita Sciences Llc | Transdermal patch and method for delivery of vitamin B12 |
| US20150150790A1 (en) * | 2013-12-04 | 2015-06-04 | Jao Hung Biotechnology Co., Ltd. | Transdermal enhancer |
| KR20190003535A (ko) * | 2016-03-31 | 2019-01-09 | 스마테크 토피칼, 인코포레이티드 | 전달 시스템 |
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2016
- 2016-04-22 DE DE102016107563.9A patent/DE102016107563A1/de active Pending
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2017
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- 2017-04-21 RU RU2018140968A patent/RU2018140968A/ru unknown
- 2017-04-21 WO PCT/EP2017/059496 patent/WO2017182619A1/de not_active Ceased
- 2017-04-21 CN CN201780025027.8A patent/CN109195586A/zh active Pending
- 2017-04-21 US US16/094,659 patent/US20190111139A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014016277A2 (de) | 2012-07-24 | 2014-01-30 | Azoba Health Care Ag | Vitaminzubereitung |
Also Published As
| Publication number | Publication date |
|---|---|
| CN109195586A (zh) | 2019-01-11 |
| US20190111139A1 (en) | 2019-04-18 |
| RU2018140968A3 (https=) | 2020-06-08 |
| RU2018140968A (ru) | 2020-05-22 |
| JP2019515910A (ja) | 2019-06-13 |
| JP7344641B2 (ja) | 2023-09-14 |
| WO2017182619A1 (de) | 2017-10-26 |
| EP3445333A1 (de) | 2019-02-27 |
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