DE102010012437A1 - Mehrphasige Biomaterialien auf Basis bakteriell synthetisierter Nanocellulose und Verfahren zu ihrer Herstellung - Google Patents
Mehrphasige Biomaterialien auf Basis bakteriell synthetisierter Nanocellulose und Verfahren zu ihrer Herstellung Download PDFInfo
- Publication number
- DE102010012437A1 DE102010012437A1 DE201010012437 DE102010012437A DE102010012437A1 DE 102010012437 A1 DE102010012437 A1 DE 102010012437A1 DE 201010012437 DE201010012437 DE 201010012437 DE 102010012437 A DE102010012437 A DE 102010012437A DE 102010012437 A1 DE102010012437 A1 DE 102010012437A1
- Authority
- DE
- Germany
- Prior art keywords
- bnc
- cellulose
- bacterial cellulose
- different bacterial
- networks
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B15/00—Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
- C08B15/10—Crosslinking of cellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31971—Of carbohydrate
- Y10T428/31975—Of cellulosic next to another carbohydrate
- Y10T428/31978—Cellulosic next to another cellulosic
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials Engineering (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Polymers & Plastics (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Composite Materials (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE201010012437 DE102010012437A1 (de) | 2010-03-19 | 2010-03-19 | Mehrphasige Biomaterialien auf Basis bakteriell synthetisierter Nanocellulose und Verfahren zu ihrer Herstellung |
| CA2792381A CA2792381C (en) | 2010-03-19 | 2011-03-15 | Multi-phase bacterially-synthesized-nanocellulose biomaterials and method for producing same |
| PCT/DE2011/000269 WO2011113423A1 (de) | 2010-03-19 | 2011-03-15 | Mehrphasige biomaterialien auf basis bakteriell synthetisierter nanocellulose und verfahren zu ihrer herstellung |
| ES11718257.6T ES2636481T3 (es) | 2010-03-19 | 2011-03-15 | Biomateriales multifásicos a base de nanocelulosa sintetizada por bacterias y procedimiento para su producción |
| PL11718257T PL2547372T3 (pl) | 2010-03-19 | 2011-03-15 | Wielofazowe biomateriały na bazie bakteryjnie zsyntetyzowanej nanocelulozy i sposób ich wytwarzania |
| JP2012557407A JP5975221B2 (ja) | 2010-03-19 | 2011-03-15 | バクテリア合成ナノセルロースに基づく多相生体材料とその製造方法 |
| CN201180013216.6A CN102791300B (zh) | 2010-03-19 | 2011-03-15 | 基于细菌合成的纳米纤维素的多相生物材料及其制造方法 |
| EP11718257.6A EP2547372B1 (de) | 2010-03-19 | 2011-03-15 | Mehrphasige biomaterialien auf basis bakteriell synthetisierter nanocellulose und verfahren zu ihrer herstellung |
| US13/634,788 US20130004784A1 (en) | 2010-03-19 | 2011-03-15 | Multi-phase bacterially-synthesized-nanocellulose biomaterials and method for producing the same |
| US14/597,235 US10829567B2 (en) | 2010-03-19 | 2015-01-15 | Multi-phase bacterially-synthesized-nanocellulose biomaterials and method for producing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE201010012437 DE102010012437A1 (de) | 2010-03-19 | 2010-03-19 | Mehrphasige Biomaterialien auf Basis bakteriell synthetisierter Nanocellulose und Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE102010012437A1 true DE102010012437A1 (de) | 2011-09-22 |
Family
ID=44141021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE201010012437 Ceased DE102010012437A1 (de) | 2010-03-19 | 2010-03-19 | Mehrphasige Biomaterialien auf Basis bakteriell synthetisierter Nanocellulose und Verfahren zu ihrer Herstellung |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20130004784A1 (enExample) |
| EP (1) | EP2547372B1 (enExample) |
| JP (1) | JP5975221B2 (enExample) |
| CN (1) | CN102791300B (enExample) |
| CA (1) | CA2792381C (enExample) |
| DE (1) | DE102010012437A1 (enExample) |
| ES (1) | ES2636481T3 (enExample) |
| PL (1) | PL2547372T3 (enExample) |
| WO (1) | WO2011113423A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102010012437A1 (de) | 2010-03-19 | 2011-09-22 | Friedrich-Schiller-Universität Jena | Mehrphasige Biomaterialien auf Basis bakteriell synthetisierter Nanocellulose und Verfahren zu ihrer Herstellung |
| CN103285427B (zh) * | 2013-04-26 | 2014-11-05 | 中国国旅贸易有限责任公司 | 一种人工骨材料及其制备方法 |
| WO2016113400A1 (en) * | 2015-01-15 | 2016-07-21 | JeNaCell GmbH | Multi-phase bacterially-synthesized-nanocellulose biomaterials and method for producing the same |
| US10682257B2 (en) | 2015-07-29 | 2020-06-16 | Evophancie Biotech Ltd | Biological fiber composite dressing |
| EP3123988B8 (en) * | 2015-07-29 | 2018-06-27 | Harvest Belle Biotech | Biological fiber composite dressing |
| EP3900699B1 (en) * | 2015-11-25 | 2023-08-02 | JeNaCell GmbH | Biotechnologically-produced cellulose-containing article for dermatological use |
| CN107522893A (zh) * | 2017-07-13 | 2017-12-29 | 天津大学 | 一种抗菌复合细菌纤维素膜的制备方法 |
| CN109224122A (zh) * | 2018-09-20 | 2019-01-18 | 天津科技大学 | 一种抗菌液体创可贴及其制备方法 |
| ES2980503T3 (es) * | 2019-03-28 | 2024-10-01 | Next Gen Leather S L | Material alternativo al cuero |
| AU2020273022B2 (en) | 2019-04-11 | 2025-05-01 | DePuy Synthes Products, Inc. | Bacterial derived nanocellulose textile material |
| US20220241176A1 (en) | 2019-07-12 | 2022-08-04 | Evonik Operations Gmbh | Method for loading of microorganisms on multiphase biomaterials |
| KR102295345B1 (ko) * | 2019-11-12 | 2021-08-30 | 충북대학교 산학협력단 | 증대된 박테리아 나노셀룰로오스 생산능을 갖는 글루콘아세토박터 한세니 돌연변이 균주 및 이를 이용한 박테리아 나노셀룰로오스 생산방법 |
| DE102020210058A1 (de) | 2020-08-07 | 2022-02-10 | Volkswagen Aktiengesellschaft | Bezugsmaterial, insbesondere für ein Fahrzeug-Interieurbauteil |
| DE102021116255A1 (de) * | 2021-06-23 | 2022-12-29 | Hybrid Reality GmbH | Verfahren zur herstellung eines utensils umfassend mehrere utensil-elemente |
| EP4529919A1 (en) | 2023-09-29 | 2025-04-02 | Evonik Operations GmbH | Solid self-nanoemulsifying drug delivery system having biosynthetic cellulose as adsorbent |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0206830A2 (en) * | 1985-06-27 | 1986-12-30 | Johnson & Johnson Products Inc. | Microbial polysaccharide articles and methods of production |
| US4950597A (en) * | 1988-05-25 | 1990-08-21 | The University Of Texas Board Of Regents | Modification of cellulose normally synthesizied by cellulose-producing microorganisms |
| EP0347481B1 (en) * | 1987-03-09 | 1995-04-12 | Board Of Regents, The University Of Texas System | Multiribbon microbial cellulose |
| US5472859A (en) * | 1993-08-02 | 1995-12-05 | Brown, Jr.; R. Malcolm | Enzymatic method for synthesis of cellulose 1 |
| JPH10201495A (ja) | 1997-01-22 | 1998-08-04 | Bio Polymer Res:Kk | セルロース生産菌とその他の微生物との混合培養によるバクテリアセルロースの製造方法 |
| US6429002B1 (en) * | 1985-10-18 | 2002-08-06 | Cp Kelco U.S., Inc. | Reticulated cellulose producing acetobacter strains |
| KR20020067226A (ko) | 2001-02-16 | 2002-08-22 | 변유량 | 혼합배양에 의한 미생물 셀룰로오스의 생산방법 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997048730A1 (en) * | 1996-06-21 | 1997-12-24 | Bio-Polymer Research Co., Ltd. | Methods for processing bacterial cellulose |
| US20040109853A1 (en) * | 2002-09-09 | 2004-06-10 | Reactive Surfaces, Ltd. | Biological active coating components, coatings, and coated surfaces |
| US20060062768A1 (en) * | 2004-09-23 | 2006-03-23 | Olexander Hnojewyj | Biocompatible hydrogel compositions |
| WO2007027849A2 (en) | 2005-08-31 | 2007-03-08 | Board Of Regents, The University Of Texas System | Multiribbon nanocellulose as a matrix for wound healing |
| CN1850302A (zh) * | 2006-05-19 | 2006-10-25 | 东华大学 | 一种人造皮肤用细菌纤维素湿膜的制备方法 |
| CN100460020C (zh) * | 2006-11-14 | 2009-02-11 | 东华大学 | 一种相互粘连多层细菌纤维素膜的制备方法 |
| ITTO20060932A1 (it) * | 2006-12-29 | 2008-06-30 | Medestea Res & Production S P A | Procedimento per la produzione di una pellicola a base di cellulosa, da utilizzare per la copertura, riparazione, rigenerazione e cicatrizzazione di lesioni cutanee e tissutali e pellicola cosi' ottenuta. |
| JP5470572B2 (ja) * | 2007-07-19 | 2014-04-16 | 憲司 中村 | 含浸用シート及びそれを用いたウェットシート製品 |
| JP4314292B2 (ja) * | 2007-09-25 | 2009-08-12 | 憲司 中村 | 化粧用ティッシュペーパー |
| US20090209897A1 (en) * | 2008-02-20 | 2009-08-20 | Lotec, Inc. Dba Vesta Sciences, Inc. | Photoactivated Antimicrobial Wound Dressing and Method Relating Thereto |
| WO2009123759A2 (en) * | 2008-04-02 | 2009-10-08 | Moerae Matrix, Inc. | Therapeutic uses of biocompatible biogel compositions |
| CN101288778A (zh) * | 2008-06-18 | 2008-10-22 | 天津大学 | 多孔细菌纤维素海绵的制备方法 |
| CN101509026A (zh) * | 2009-03-27 | 2009-08-19 | 上海应用技术学院 | 一种细菌纤维素复合膜及其制备方法和应用 |
| CN101570616A (zh) | 2009-06-08 | 2009-11-04 | 天津科技大学 | 一种细菌纤维素/聚乙烯醇复合凝胶材料及其制备方法 |
| DE102010012437A1 (de) | 2010-03-19 | 2011-09-22 | Friedrich-Schiller-Universität Jena | Mehrphasige Biomaterialien auf Basis bakteriell synthetisierter Nanocellulose und Verfahren zu ihrer Herstellung |
-
2010
- 2010-03-19 DE DE201010012437 patent/DE102010012437A1/de not_active Ceased
-
2011
- 2011-03-15 US US13/634,788 patent/US20130004784A1/en not_active Abandoned
- 2011-03-15 PL PL11718257T patent/PL2547372T3/pl unknown
- 2011-03-15 WO PCT/DE2011/000269 patent/WO2011113423A1/de not_active Ceased
- 2011-03-15 ES ES11718257.6T patent/ES2636481T3/es active Active
- 2011-03-15 CN CN201180013216.6A patent/CN102791300B/zh not_active Expired - Fee Related
- 2011-03-15 EP EP11718257.6A patent/EP2547372B1/de active Active
- 2011-03-15 JP JP2012557407A patent/JP5975221B2/ja active Active
- 2011-03-15 CA CA2792381A patent/CA2792381C/en not_active Expired - Fee Related
-
2015
- 2015-01-15 US US14/597,235 patent/US10829567B2/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0206830A2 (en) * | 1985-06-27 | 1986-12-30 | Johnson & Johnson Products Inc. | Microbial polysaccharide articles and methods of production |
| US6429002B1 (en) * | 1985-10-18 | 2002-08-06 | Cp Kelco U.S., Inc. | Reticulated cellulose producing acetobacter strains |
| EP0347481B1 (en) * | 1987-03-09 | 1995-04-12 | Board Of Regents, The University Of Texas System | Multiribbon microbial cellulose |
| US4950597A (en) * | 1988-05-25 | 1990-08-21 | The University Of Texas Board Of Regents | Modification of cellulose normally synthesizied by cellulose-producing microorganisms |
| US5472859A (en) * | 1993-08-02 | 1995-12-05 | Brown, Jr.; R. Malcolm | Enzymatic method for synthesis of cellulose 1 |
| JPH10201495A (ja) | 1997-01-22 | 1998-08-04 | Bio Polymer Res:Kk | セルロース生産菌とその他の微生物との混合培養によるバクテリアセルロースの製造方法 |
| KR20020067226A (ko) | 2001-02-16 | 2002-08-22 | 변유량 | 혼합배양에 의한 미생물 셀룰로오스의 생산방법 |
Non-Patent Citations (27)
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| A. Nakayama, A. Kakugo, J. P. Gong, Y. Osada, M. Takai, T. Erata, S. Kawano: High mechanical strength double-network hydrogel with bacterial cellulose, Advanced Functional Materials (2004), 14/11, 1124-8 |
| A. Seto, Y. Saito, M. Matsushige, H. Kobayashi, Y. Sasaki, N. Tonouchi, T. Tsuchida, F. Yoshinaga, K. Ueda, T. Beppu: Effective cellulose production by a coculture of Gluconacetobacter xylinus and Lactobacillus mali, Applied Microbiology and Biotechnology (2006), 73(4), 915-921 |
| B. R. Evans, H. M. O'Neill, E. Greenbaum: Electron Transfer by Enzymes and Photosynthetic Proteins Immobilized in Polysaccharide Composites, Abstracts, 57th Southeast/61st Southwest Joint Regional Meeting of the American Chemical Society, Memphis, TN, United States, November 1-4, 2005 |
| B. R. Evans, H. O'Neil, M. Hugh, V. P. Malyvanh, I. Lee, J. Woodward: Palladium-bacterial cellulose membranes for fuel cells, Biosensors & Bioelectronics (2003), 18/7, 917-23 |
| C. H. Haigler, A. R. White, R. M. Brown Jr., K. M. Cooper: Alteration of In Vivo Cellulose Ribbon Assembly by Carboxymethylcellulose and Other Cellulose Derivative, J Cell Biology (1982), 94, 64-9 |
| Chemical Abstracts Nr.123:193295 * |
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| D. Klemm, D. Schumann, F. Kramer, N. Heßler, M. Hornung, H.-P. Schmauder, S. Marsch: Nanocelluloses as Innovative Polymers in Research and Application. Advances in Polymer Science (2006), 205(Polysaccharides II), 49-96 |
| D. Zhang, L. Qi: Synthesis of mesoporous titania networks consisting of anatase nanowires by templating of bacterial cellulose membranes, Chem. Commun. (2005), 21, 2735-7 |
| Daoud, J. H. Xin, Y.-H. Zhang: Surface functionalization of cellulose fibers with titanium dioxide nanoparticles and their combined bactericidal activities, Surface Science (2005), 599(1-3), 69-75 |
| G. Serafica, R. Mormino, H. Bungay: Inclusion of solid particles in bacterial cellulose, Applied Microbiology and Biotechnology (2002), 58/6, 756-60 |
| H. Wang, F. Guan, X. Ma, S. Ren: Production and performance determination of modified bacterial cellulose, Shipin Keji (2009), (5), 28-31 |
| H. Yano, S. Nakahara: Bio-composites produced from plant microfiber bundles with a nanometer unit web-like network, Journal of Materials Science (2004), 39/5, 1635-8 |
| J. Cybulska, E. Vanstreels, Q. T. Ho, C. M. Courtin, V. Van Craeyveld, B. Nicolai, A. Zdunek, K. Konstankiewicz: Mechanical characteristics of artificial cell walls, Journal of Food Engineering (2009), 96(2), 287-294 |
| K. Tajima, H. Ito, M. Fujiwara, M. Takai, J. Hayashi: Enhancement of bacterial cellulose productivity and preparation of branched polysaccharide-bacterial cellulose composite by co-cultivation of Acetobacter species, Sen'i Gakkaishi (1995), 51(7), 323-32 |
| K. Tajima, M. Fujiwara, M. Takai: Biological control of cellulose. Macromolecular Symposia (1995), 99 (Functional Polysaccharides), 149-55 |
| K. Yasuda, J. P. Gong, Y. Katsuyama, A. Nakayama, Y. Tanabe, E. Kondo, M. Ueno, Y. Osada: Biomechanical properties of high-toughness double network hydrogels, Biomaterials (2005), 26/2, 4468-75 |
| K.-Y. Lee, J. J. Blaker, A. Bismarck: Surface functionalisation of bacterial cellulose as the route to produce green polylactide nanocomposites with improved properties, Composites Science and Technology (2009), 69(15-16), 2724-2733 |
| M. Seifert: Modifizierung der Struktur von Bakteriencellulose durch die Zusammenstellung des Nährmediums bei der Kultivierung von Acetobacter xylinum, Promotionsarbeit, Friedrich-Schiller-Universität Jena, 2004 |
| N. Hessler, D. Klemm: Alteration of bacterial nanocellulose structure by in situ modification using polyethylene glycol and carbohydrate additives, Cellulose (Dordrecht, Netherlands) (2009), 16(5), 899-910 |
| N. Sakairi, H. Asano, M. Ogawa, N. Nishi, S. Tokura: A method for direct harvest of bacterial cellulose filaments during continuous cultivation of acetobacter xylinum. Carbohydrate Polymers (1998), 35/3-4, 233-7 |
| O. M. Astley, E. Chanliaud, A. M. Donald, M. J. Gidley: Structure of Acetobacter cellulose composites in the hydrated state, International journal of biological macromolecules (2001), 29/3, 193-202 |
| T. Wan, Y. Zhu: Preparation of bacterial cellulose/poly(vinyl alcohol) composite gels, Faming Zhuanli Shenqing Gongkai Shuomingshu CN 101570616, 2009 |
| U. Udhardt: Synthese, Eigenschaften und Strukturdesign von Bakteriencellulose mit speziellem Anwendungspotential von BASYC(RTM)-Implantaten in der Mikrochirurgie, Promotionsarbeit, Friedrich-Schiller-Universität Jena, 2004 |
| V. Dubey, C. Saxena, L. Singh, K. V. Ramana, R. S. Chauhan: Pervaporation of binary water-ethanol mixtures through bacterial cellulose membrane, Separation and Purification Technology (2002), 27/2, 163-71 |
| V. Dubey, L. K. Pandey, C. Saxena: Pervaporative separation of ethanol/water azeotrope using a novel chitosan-impregnated bacterial cellulose membrane and chitosan-poly(vinyl alcohol)blends, Journal of Membrane Science (2005), 251(1-2), 131-136 |
| W. A. Daoud, J. H. Xin, Y.-H. Zhang: Surface functionalization of cellulose fibers with titanium dioxide nanoparticles and their combined bactericidal activities, Surface Science (2005), 599(1-3), 69-75 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102791300A (zh) | 2012-11-21 |
| US20130004784A1 (en) | 2013-01-03 |
| ES2636481T3 (es) | 2017-10-05 |
| JP2013522399A (ja) | 2013-06-13 |
| JP5975221B2 (ja) | 2016-08-23 |
| US20150225486A1 (en) | 2015-08-13 |
| PL2547372T3 (pl) | 2017-10-31 |
| CA2792381C (en) | 2018-09-25 |
| CN102791300B (zh) | 2015-07-29 |
| EP2547372B1 (de) | 2017-05-10 |
| US10829567B2 (en) | 2020-11-10 |
| WO2011113423A1 (de) | 2011-09-22 |
| EP2547372A1 (de) | 2013-01-23 |
| CA2792381A1 (en) | 2011-09-22 |
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