DE102007042218A1 - Verfahren und Vorrichtung zur sterilen oder aseptischen Handhabung von Behältnissen - Google Patents
Verfahren und Vorrichtung zur sterilen oder aseptischen Handhabung von Behältnissen Download PDFInfo
- Publication number
- DE102007042218A1 DE102007042218A1 DE102007042218A DE102007042218A DE102007042218A1 DE 102007042218 A1 DE102007042218 A1 DE 102007042218A1 DE 102007042218 A DE102007042218 A DE 102007042218A DE 102007042218 A DE102007042218 A DE 102007042218A DE 102007042218 A1 DE102007042218 A1 DE 102007042218A1
- Authority
- DE
- Germany
- Prior art keywords
- container
- stopper
- negative pressure
- containers
- plug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000034 method Methods 0.000 title claims abstract description 24
- 238000012360 testing method Methods 0.000 claims description 11
- 230000003287 optical effect Effects 0.000 claims description 7
- 238000005259 measurement Methods 0.000 claims description 4
- 238000012552 review Methods 0.000 claims description 3
- 230000001954 sterilising effect Effects 0.000 description 10
- 238000004659 sterilization and disinfection Methods 0.000 description 10
- 230000005855 radiation Effects 0.000 description 6
- 239000007788 liquid Substances 0.000 description 5
- 238000011161 development Methods 0.000 description 4
- 230000018109 developmental process Effects 0.000 description 4
- 238000005429 filling process Methods 0.000 description 4
- 230000036512 infertility Effects 0.000 description 4
- 230000001012 protector Effects 0.000 description 4
- 238000001228 spectrum Methods 0.000 description 3
- 238000001514 detection method Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- BUHVIAUBTBOHAG-FOYDDCNASA-N (2r,3r,4s,5r)-2-[6-[[2-(3,5-dimethoxyphenyl)-2-(2-methylphenyl)ethyl]amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol Chemical compound COC1=CC(OC)=CC(C(CNC=2C=3N=CN(C=3N=CN=2)[C@H]2[C@@H]([C@H](O)[C@@H](CO)O2)O)C=2C(=CC=CC=2)C)=C1 BUHVIAUBTBOHAG-FOYDDCNASA-N 0.000 description 1
- 238000012369 In process control Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000002788 crimping Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000011143 downstream manufacturing Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000010894 electron beam technology Methods 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000020169 heat generation Effects 0.000 description 1
- 238000010965 in-process control Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000004886 process control Methods 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
- B65B55/02—Sterilising, e.g. of complete packages
- B65B55/027—Packaging in aseptic chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B31/00—Packaging articles or materials under special atmospheric or gaseous conditions; Adding propellants to aerosol containers
- B65B31/02—Filling, closing, or filling and closing, containers or wrappers in chambers maintained under vacuum or superatmospheric pressure or containing a special atmosphere, e.g. of inert gas
- B65B31/025—Filling, closing, or filling and closing, containers or wrappers in chambers maintained under vacuum or superatmospheric pressure or containing a special atmosphere, e.g. of inert gas specially adapted for rigid or semi-rigid containers
- B65B31/027—Filling, closing, or filling and closing, containers or wrappers in chambers maintained under vacuum or superatmospheric pressure or containing a special atmosphere, e.g. of inert gas specially adapted for rigid or semi-rigid containers closed by a stopper
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B7/00—Closing containers or receptacles after filling
- B65B7/16—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons
- B65B7/28—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers
- B65B7/2821—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers applying plugs or threadless stoppers
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Filling Of Jars Or Cans And Processes For Cleaning And Sealing Jars (AREA)
- Sealing Of Jars (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Examining Or Testing Airtightness (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102007042218A DE102007042218A1 (de) | 2007-09-05 | 2007-09-05 | Verfahren und Vorrichtung zur sterilen oder aseptischen Handhabung von Behältnissen |
| US12/676,071 US20100180551A1 (en) | 2007-09-05 | 2008-07-07 | Method and apparatus for sterile or aseptic handling of containers |
| AT08774844T ATE526242T1 (de) | 2007-09-05 | 2008-07-07 | Verfahren und vorrichtung zur sterilen oder aseptischen handhabung von behältnissen |
| DK08774844.8T DK2190747T3 (da) | 2007-09-05 | 2008-07-07 | Fremgangsmåde og apparatur til sterilt eller aseptisk håndtering af beholdere |
| PCT/EP2008/058796 WO2009030545A1 (de) | 2007-09-05 | 2008-07-07 | Verfahren und vorrichtung zur sterilen oder aseptischen handhabung von behältnissen |
| EP08774844A EP2190747B1 (de) | 2007-09-05 | 2008-07-07 | Verfahren und vorrichtung zur sterilen oder aseptischen handhabung von behältnissen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102007042218A DE102007042218A1 (de) | 2007-09-05 | 2007-09-05 | Verfahren und Vorrichtung zur sterilen oder aseptischen Handhabung von Behältnissen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE102007042218A1 true DE102007042218A1 (de) | 2009-03-12 |
Family
ID=39743148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE102007042218A Withdrawn DE102007042218A1 (de) | 2007-09-05 | 2007-09-05 | Verfahren und Vorrichtung zur sterilen oder aseptischen Handhabung von Behältnissen |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20100180551A1 (da) |
| EP (1) | EP2190747B1 (da) |
| AT (1) | ATE526242T1 (da) |
| DE (1) | DE102007042218A1 (da) |
| DK (1) | DK2190747T3 (da) |
| WO (1) | WO2009030545A1 (da) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102009027452A1 (de) * | 2009-07-03 | 2011-01-05 | Robert Bosch Gmbh | Vorrichtung zum Füllen und Verschließen von pharmazeutischen Bahältnissen |
| DE102012103899A1 (de) * | 2012-05-03 | 2013-11-07 | Schott Ag | Verfahren und Vorrichtung zur Behandlung von Behältern zur Aufbewahrung von Substanzen für medizinische oder pharmazeutische Anwendungen |
| US9522752B2 (en) | 2012-05-03 | 2016-12-20 | Schott Ag | Process and apparatus for treating containers for storing substances for medical, pharmaceutical or cosmetic applications |
| EP3225559A1 (de) * | 2016-04-01 | 2017-10-04 | Selo Deutschland GmbH | Verfahren zur automatisierten befüllung eines beutels sowie befüllungs-vorrichtung |
| US10124928B2 (en) | 2012-07-13 | 2018-11-13 | Schott Ag | Holding structure for concurrently holding a plurality of containers for substances for medical, pharmaceutical or cosmetic applications as well as transport or packaging container comprising the same |
| CN113895721A (zh) * | 2021-10-26 | 2022-01-07 | 包梦蛟 | 一种无菌包装装置及其方法 |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2955563B1 (fr) * | 2010-01-26 | 2013-09-06 | Spc France | Machine pour remplir une pluralite de recipients, systeme incluant une telle machine et procede de fabrication afferent |
| EP3208202B1 (en) * | 2010-08-06 | 2019-11-20 | Hospira Australia Pty Ltd | System for producing vials containing a substance comprising an oxygen-sensitive formulation |
| US10524980B2 (en) * | 2016-09-13 | 2020-01-07 | Vanrx Pharmasystems, Inc. | Apparatus and method for aseptically filling pharmaceutical containers with a pharmaceutical fluid using rotary stage |
| US20130091805A1 (en) * | 2011-10-14 | 2013-04-18 | Applied Silicone Corporation | System and method for curing, sterilization and aseptic packaging of medical devices |
| ES2643052T3 (es) * | 2012-05-03 | 2017-11-21 | Vanrx Pharmasystems Inc. | Sistema de retirada de cubierta para uso en recintos de entorno controlado |
| JP6336327B2 (ja) * | 2013-05-08 | 2018-06-06 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 生物学的サンプルを収容する容器のためのキャップ供給装置 |
| JP6709023B2 (ja) * | 2015-06-30 | 2020-06-10 | 株式会社安川電機 | 薬液充填システム、薬液充填方法、ロボットシステム、及びトレイ |
| US11530064B2 (en) * | 2016-09-13 | 2022-12-20 | Vanrx Pharmasystems Inc. | Apparatus and method for monitoring and controlling the removal of a cover from a sealed tube in an aseptic environment |
| US11981473B2 (en) | 2020-09-27 | 2024-05-14 | V Anrx Pharmasystems Inc. | Cover removal system for use in controlled environment enclosures |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4004965A1 (de) * | 1990-02-19 | 1991-08-22 | Sensys Gmbh & Co Kg | Pruefverfahren und vorrichtung zur durchfuehrung desselben |
| DE3872906T2 (de) * | 1987-03-27 | 1992-12-03 | Toyo Glass Co Ltd | Einrichtung zum ueberpruefen der groesse des vakuums in einem geschlossenen behaelter. |
| JP2004175395A (ja) * | 2002-11-27 | 2004-06-24 | Daiwa Can Co Ltd | 密封容器の内圧検査方法および装置 |
| EP1447328B1 (en) | 2003-01-21 | 2007-02-14 | Grifols, S.A. | A method for the sterile dosing of vials |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2700497A (en) * | 1950-02-02 | 1955-01-25 | Merck & Co Inc | Bottle stoppering machine |
| US3247640A (en) * | 1960-06-06 | 1966-04-26 | Colgate Palmolive Co | Filling aerosol containers |
| DE2033031A1 (de) * | 1970-07-03 | 1972-01-13 | Fa Hermann Heye, 4962 Obernkirchen | Element einer Maschine, z B Kronen korkverschließelement einer Kronenkorkver schließmaschine |
| US3805594A (en) * | 1971-10-19 | 1974-04-23 | Mitsubishi Heavy Ind Ltd | Pressure testing apparatus for bottles |
| US3802252A (en) * | 1972-06-09 | 1974-04-09 | Benthos Inc | Pressure and vacuum monitoring apparatus |
| US3995479A (en) * | 1974-11-01 | 1976-12-07 | Schlumberger Technology Corporation | Apparatus for protecting downhole instruments from torsional and lateral movements |
| US4364485A (en) * | 1981-05-15 | 1982-12-21 | Schering Corporation | Injectable fluid container and method |
| US4511044A (en) * | 1982-02-24 | 1985-04-16 | The West Company | Seal force monitor apparatus, system, and method for in-process determination of integrity of sealed containers |
| US4788850A (en) * | 1987-04-06 | 1988-12-06 | Five X Corporation | Bottle testing apparatus |
| US5033254A (en) * | 1990-04-19 | 1991-07-23 | American National Can Company | Head-space calibrated liquified gas dispensing system |
| US5232839A (en) * | 1990-06-14 | 1993-08-03 | Difco Laboratories Incorporated | Detecting microbiological growth |
| US5548992A (en) * | 1995-06-06 | 1996-08-27 | The United States Of America As Represented By The United States Department Of Energy | Leak test adapter for containers |
| DE69914725T2 (de) * | 1998-03-13 | 2004-12-02 | Becton, Dickinson And Co. | Verfahren zum zusammensetzen und verpacken von medizinischen vorrichtungen |
| US5939620A (en) * | 1998-04-24 | 1999-08-17 | Crown Cork & Seal Technologies Coporation | Leak detecting device for detecting a leak in a container |
| NZ509001A (en) * | 1998-06-29 | 2003-10-31 | Astrapak Ltd | Plug and gland aseptic package system |
| US5996401A (en) * | 1998-08-27 | 1999-12-07 | The United States Of America As Represented By The Secretary Of The Navy | Leak test adapter system |
| CA2516256A1 (en) * | 2003-02-19 | 2004-09-02 | The Coca-Cola Company | System and method for aseptic filling of packages with liquid products |
-
2007
- 2007-09-05 DE DE102007042218A patent/DE102007042218A1/de not_active Withdrawn
-
2008
- 2008-07-07 WO PCT/EP2008/058796 patent/WO2009030545A1/de active Application Filing
- 2008-07-07 DK DK08774844.8T patent/DK2190747T3/da active
- 2008-07-07 US US12/676,071 patent/US20100180551A1/en not_active Abandoned
- 2008-07-07 EP EP08774844A patent/EP2190747B1/de not_active Not-in-force
- 2008-07-07 AT AT08774844T patent/ATE526242T1/de active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3872906T2 (de) * | 1987-03-27 | 1992-12-03 | Toyo Glass Co Ltd | Einrichtung zum ueberpruefen der groesse des vakuums in einem geschlossenen behaelter. |
| DE4004965A1 (de) * | 1990-02-19 | 1991-08-22 | Sensys Gmbh & Co Kg | Pruefverfahren und vorrichtung zur durchfuehrung desselben |
| JP2004175395A (ja) * | 2002-11-27 | 2004-06-24 | Daiwa Can Co Ltd | 密封容器の内圧検査方法および装置 |
| EP1447328B1 (en) | 2003-01-21 | 2007-02-14 | Grifols, S.A. | A method for the sterile dosing of vials |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102009027452A1 (de) * | 2009-07-03 | 2011-01-05 | Robert Bosch Gmbh | Vorrichtung zum Füllen und Verschließen von pharmazeutischen Bahältnissen |
| DE102012103899A1 (de) * | 2012-05-03 | 2013-11-07 | Schott Ag | Verfahren und Vorrichtung zur Behandlung von Behältern zur Aufbewahrung von Substanzen für medizinische oder pharmazeutische Anwendungen |
| DE102012103899B4 (de) * | 2012-05-03 | 2016-09-22 | Schott Ag | Verfahren und Vorrichtung zur Behandlung von Behältern zur Aufbewahrung von Substanzen für medizinische oder pharmazeutische Anwendungen |
| US9522752B2 (en) | 2012-05-03 | 2016-12-20 | Schott Ag | Process and apparatus for treating containers for storing substances for medical, pharmaceutical or cosmetic applications |
| US9828124B2 (en) | 2012-05-03 | 2017-11-28 | Schott Ag | Process and apparatus for treating containers for storing substances for medical, pharmaceutical or cosmetic applications |
| US10124928B2 (en) | 2012-07-13 | 2018-11-13 | Schott Ag | Holding structure for concurrently holding a plurality of containers for substances for medical, pharmaceutical or cosmetic applications as well as transport or packaging container comprising the same |
| US10287056B2 (en) | 2012-07-13 | 2019-05-14 | Schott Ag | Holding structure for concurrently holding a plurality of containers for substances for medical, pharmaceutical or cosmetic applications as well as transport or packaging container comprising the same |
| EP3225559A1 (de) * | 2016-04-01 | 2017-10-04 | Selo Deutschland GmbH | Verfahren zur automatisierten befüllung eines beutels sowie befüllungs-vorrichtung |
| CN113895721A (zh) * | 2021-10-26 | 2022-01-07 | 包梦蛟 | 一种无菌包装装置及其方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009030545A1 (de) | 2009-03-12 |
| ATE526242T1 (de) | 2011-10-15 |
| US20100180551A1 (en) | 2010-07-22 |
| EP2190747B1 (de) | 2011-09-28 |
| EP2190747A1 (de) | 2010-06-02 |
| DK2190747T3 (da) | 2012-01-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OM8 | Search report available as to paragraph 43 lit. 1 sentence 1 patent law | ||
| R119 | Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee |
Effective date: 20130403 |