DE10143813A1 - Infektiöser Rindervirusdiarrhoe-Virusklon - Google Patents

Infektiöser Rindervirusdiarrhoe-Virusklon

Info

Publication number
DE10143813A1
DE10143813A1 DE10143813A DE10143813A DE10143813A1 DE 10143813 A1 DE10143813 A1 DE 10143813A1 DE 10143813 A DE10143813 A DE 10143813A DE 10143813 A DE10143813 A DE 10143813A DE 10143813 A1 DE10143813 A1 DE 10143813A1
Authority
DE
Germany
Prior art keywords
bvdv
rna
clone
dna
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE10143813A
Other languages
German (de)
English (en)
Inventor
Knut Elbers
Christiane Meyer
Martina Von Freyburg
Gregor Meyers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Vetmedica GmbH
Original Assignee
Boehringer Ingelheim Vetmedica GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmedica GmbH filed Critical Boehringer Ingelheim Vetmedica GmbH
Priority to DE10143813A priority Critical patent/DE10143813A1/de
Priority to UY27434A priority patent/UY27434A1/es
Priority to PL02368748A priority patent/PL368748A1/xx
Priority to HU0401585A priority patent/HUP0401585A3/hu
Priority to CNA028175115A priority patent/CN1551913A/zh
Priority to JP2003527105A priority patent/JP4416504B2/ja
Priority to DK06011790.0T priority patent/DK1749885T3/da
Priority to EP02797952A priority patent/EP1440149B1/en
Priority to KR10-2004-7002362A priority patent/KR20040039295A/ko
Priority to ES06011790T priority patent/ES2401072T3/es
Priority to PCT/EP2002/009925 priority patent/WO2003023041A2/en
Priority to EP06011790A priority patent/EP1749885B8/en
Priority to MXPA04002124A priority patent/MXPA04002124A/es
Priority to CA2457441A priority patent/CA2457441C/en
Priority to DE60213639T priority patent/DE60213639T2/de
Priority to AT02797952T priority patent/ATE335074T1/de
Priority to BR0212312-6A priority patent/BR0212312A/pt
Priority to US10/236,542 priority patent/US7135561B2/en
Priority to ARP020103361A priority patent/AR036432A1/es
Publication of DE10143813A1 publication Critical patent/DE10143813A1/de
Priority to US11/524,356 priority patent/US20070015203A1/en
Priority to JP2009180719A priority patent/JP2009291203A/ja
Priority to US13/364,259 priority patent/US8778355B2/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/01DNA viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24061Methods of inactivation or attenuation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24311Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24321Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24311Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24311Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24361Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE10143813A 2001-09-06 2001-09-06 Infektiöser Rindervirusdiarrhoe-Virusklon Withdrawn DE10143813A1 (de)

Priority Applications (22)

Application Number Priority Date Filing Date Title
DE10143813A DE10143813A1 (de) 2001-09-06 2001-09-06 Infektiöser Rindervirusdiarrhoe-Virusklon
MXPA04002124A MXPA04002124A (es) 2001-09-06 2002-09-05 Clon de virus de diarrea viral bovina infeccioso y atenuado, metodos para su produccion y uso.
EP06011790A EP1749885B8 (en) 2001-09-06 2002-09-05 Infectious and attenuated bovine viral diarrhea virus vaccine
HU0401585A HUP0401585A3 (en) 2001-09-06 2002-09-05 Infectious bovine viral diarrhea virus clone
CNA028175115A CN1551913A (zh) 2001-09-06 2002-09-05 传染性和减毒的牛病毒性腹泻病毒克隆,其产生方法及用途
JP2003527105A JP4416504B2 (ja) 2001-09-06 2002-09-05 感染性ウシウイルス性下痢ウイルスクローン
DK06011790.0T DK1749885T3 (da) 2001-09-06 2002-09-05 Infektiøs og svækket kvægdiarévirus
EP02797952A EP1440149B1 (en) 2001-09-06 2002-09-05 Use of an infectious and attenuated type ii bovine viral diarrhea virus clone to prevent foetal infection by type i bvdv
CA2457441A CA2457441C (en) 2001-09-06 2002-09-05 Infectious and attenuated bovine viral diarrhea virus clone; methods for their production and use
PL02368748A PL368748A1 (en) 2001-09-06 2002-09-05 Infectious bovine viral diarrhea virus clone
PCT/EP2002/009925 WO2003023041A2 (en) 2001-09-06 2002-09-05 Infectious and attenuated bovine viral diarrhea virus clone; methods for their production and use
UY27434A UY27434A1 (es) 2001-09-06 2002-09-05 Clon del virus de la diarrea viral infecciosa bovina
ES06011790T ES2401072T3 (es) 2001-09-06 2002-09-05 Vacuna del virus de la diarrea viral infecciosa bovina
KR10-2004-7002362A KR20040039295A (ko) 2001-09-06 2002-09-05 감염성의 약독화된 소바이러스설사증 바이러스 클론, 그의생산 방법 및 용도
DE60213639T DE60213639T2 (de) 2001-09-06 2002-09-05 VERWENDUNG EINES KLONES VON INFEKTIÖSEN UND ATTENUIERTEN Typ II RINDERDIARRHÖVIREN UM FÖTAL INFEKTION VON TYP I BVDV ZU VERMEIDEN
AT02797952T ATE335074T1 (de) 2001-09-06 2002-09-05 Verwendung eines klones von infektiösen und attenuierten typ ii rinderdiarrhöviren um fötal infektion von typ i bvdv zu vermeiden
BR0212312-6A BR0212312A (pt) 2001-09-06 2002-09-05 Clone infeccioso do vìrus da diarréia viral bovina
US10/236,542 US7135561B2 (en) 2001-09-06 2002-09-06 Infectious bovine viral diarrhea virus clone
ARP020103361A AR036432A1 (es) 2001-09-06 2002-09-06 Clon del virus de la diarrea viral infecciosa bovina
US11/524,356 US20070015203A1 (en) 2001-09-06 2006-09-20 Infectious bovine viral diarrhea virus
JP2009180719A JP2009291203A (ja) 2001-09-06 2009-08-03 感染性ウシウイルス性下痢ウイルスクローン
US13/364,259 US8778355B2 (en) 2001-09-06 2012-02-01 Infectious bovine viral diarrhea virus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10143813A DE10143813A1 (de) 2001-09-06 2001-09-06 Infektiöser Rindervirusdiarrhoe-Virusklon

Publications (1)

Publication Number Publication Date
DE10143813A1 true DE10143813A1 (de) 2003-04-10

Family

ID=7697990

Family Applications (2)

Application Number Title Priority Date Filing Date
DE10143813A Withdrawn DE10143813A1 (de) 2001-09-06 2001-09-06 Infektiöser Rindervirusdiarrhoe-Virusklon
DE60213639T Expired - Lifetime DE60213639T2 (de) 2001-09-06 2002-09-05 VERWENDUNG EINES KLONES VON INFEKTIÖSEN UND ATTENUIERTEN Typ II RINDERDIARRHÖVIREN UM FÖTAL INFEKTION VON TYP I BVDV ZU VERMEIDEN

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60213639T Expired - Lifetime DE60213639T2 (de) 2001-09-06 2002-09-05 VERWENDUNG EINES KLONES VON INFEKTIÖSEN UND ATTENUIERTEN Typ II RINDERDIARRHÖVIREN UM FÖTAL INFEKTION VON TYP I BVDV ZU VERMEIDEN

Country Status (16)

Country Link
EP (2) EP1440149B1 (enExample)
JP (2) JP4416504B2 (enExample)
KR (1) KR20040039295A (enExample)
CN (1) CN1551913A (enExample)
AR (1) AR036432A1 (enExample)
AT (1) ATE335074T1 (enExample)
BR (1) BR0212312A (enExample)
CA (1) CA2457441C (enExample)
DE (2) DE10143813A1 (enExample)
DK (1) DK1749885T3 (enExample)
ES (1) ES2401072T3 (enExample)
HU (1) HUP0401585A3 (enExample)
MX (1) MXPA04002124A (enExample)
PL (1) PL368748A1 (enExample)
UY (1) UY27434A1 (enExample)
WO (1) WO2003023041A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7179473B2 (en) 1998-06-05 2007-02-20 Boehringer Ingelheim Vetmedica Gmbh Attenuated pestiviruses
US7135561B2 (en) 2001-09-06 2006-11-14 Boehringer Ingelheim Vetmedica Gmbh Infectious bovine viral diarrhea virus clone
CN1788088B (zh) 2003-03-27 2012-09-26 渥太华健康研究学会 突变的水泡性口炎病毒及其用途
US7572455B2 (en) 2004-05-19 2009-08-11 Boehringer Ingelheim Vetmedica Gmbh Vaccine comprising an attenuated pestivirus
DE102004025452A1 (de) * 2004-05-19 2006-01-19 Boehringer Ingelheim Vetmedica Gmbh Vakzine enthaltend BVDV
UY29915A1 (es) * 2005-11-15 2007-06-29 Boehringer Ingelheim Vetmed Vacuna combinada que comprende un virus atenuado de la diarrea viral bovina
UY31930A (es) 2008-06-25 2010-01-29 Boheringer Ingelheim Pharma Kg Pestivirus atenuados recombinantes, en particular a csfv, bvdv o bdv atenuado recombinante
KR200451870Y1 (ko) * 2008-07-08 2011-01-14 박윤규 일회용 액상 내용물 용기
JP5744748B2 (ja) * 2008-12-03 2015-07-08 ゾエティス・エルエルシー 改変Ernsタンパク質を有するウシウイルス性下痢ウイルス
US8846054B2 (en) 2009-01-09 2014-09-30 Boehringer Ingelheim Vetmedica, Inc. Method of treating pregnant cows and/or heifers
CN101906487A (zh) * 2010-08-05 2010-12-08 中国兽医药品监察所 一种猪瘟病毒核酸标准物质的制备方法
EP2618841B1 (en) 2010-09-21 2016-10-19 Intervet International B.V. Bvdv vaccine
WO2014201259A1 (en) * 2013-06-12 2014-12-18 The Board Of Regents For Oklahoma State University Fluttering ear tag for bovine vaccination
CN113230394B (zh) * 2021-04-30 2024-04-30 广州源博医药科技有限公司 一种用于牛病毒性腹泻的rna疫苗及其构建方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1104676A1 (en) * 1999-11-30 2001-06-06 Boehringer Ingelheim Vetmedica Gmbh Safe attenuated bovine viral diarrhea viruses for use in pregnant cows

Also Published As

Publication number Publication date
ATE335074T1 (de) 2006-08-15
WO2003023041A3 (en) 2003-11-20
CA2457441C (en) 2013-01-08
EP1440149B1 (en) 2006-08-02
EP1749885B1 (en) 2012-12-05
DK1749885T3 (da) 2013-03-11
CA2457441A1 (en) 2003-03-20
JP4416504B2 (ja) 2010-02-17
ES2401072T3 (es) 2013-04-16
PL368748A1 (en) 2005-04-04
MXPA04002124A (es) 2004-07-08
JP2005502361A (ja) 2005-01-27
HUP0401585A3 (en) 2005-02-28
BR0212312A (pt) 2004-10-13
JP2009291203A (ja) 2009-12-17
KR20040039295A (ko) 2004-05-10
EP1749885A2 (en) 2007-02-07
WO2003023041A2 (en) 2003-03-20
EP1749885A3 (en) 2007-08-29
CN1551913A (zh) 2004-12-01
AR036432A1 (es) 2004-09-08
DE60213639T2 (de) 2007-10-18
HUP0401585A2 (hu) 2004-11-29
EP1440149A2 (en) 2004-07-28
DE60213639D1 (de) 2006-09-14
EP1749885B8 (en) 2013-01-16
UY27434A1 (es) 2003-04-30

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