DD299303A5 - Indolobenzoquinolinderivate, deren herstellung und verwendung als antiarrhythmische medikamente - Google Patents

Indolobenzoquinolinderivate, deren herstellung und verwendung als antiarrhythmische medikamente Download PDF

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Publication number
DD299303A5
DD299303A5 DD90343704A DD34370490A DD299303A5 DD 299303 A5 DD299303 A5 DD 299303A5 DD 90343704 A DD90343704 A DD 90343704A DD 34370490 A DD34370490 A DD 34370490A DD 299303 A5 DD299303 A5 DD 299303A5
Authority
DD
German Democratic Republic
Prior art keywords
compound
formula
group
hydroxy
reaction
Prior art date
Application number
DD90343704A
Other languages
German (de)
English (en)
Inventor
Toshihiko Hashimoto
Tetsuya Fukuzawa
Hidekazu Masuko
Yasuo Shimoji
Hiroyuki Koike
Hiroshi Mizuno
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ��@���������@�������k�� filed Critical ��@���������@�������k��
Publication of DD299303A5 publication Critical patent/DD299303A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/26—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P11/00—Preparation of sulfur-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cardiology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DD90343704A 1989-08-30 1990-08-29 Indolobenzoquinolinderivate, deren herstellung und verwendung als antiarrhythmische medikamente DD299303A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP22395989 1989-08-30

Publications (1)

Publication Number Publication Date
DD299303A5 true DD299303A5 (de) 1992-04-09

Family

ID=16806378

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90343704A DD299303A5 (de) 1989-08-30 1990-08-29 Indolobenzoquinolinderivate, deren herstellung und verwendung als antiarrhythmische medikamente

Country Status (10)

Country Link
EP (2) EP0674008A1 (fr)
JP (1) JPH03163078A (fr)
KR (1) KR910004624A (fr)
CN (1) CN1050386A (fr)
CA (1) CA2024252A1 (fr)
DD (1) DD299303A5 (fr)
HU (1) HU208012B (fr)
IE (1) IE903127A1 (fr)
PT (1) PT95142B (fr)
RU (1) RU2045528C1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI404702B (zh) * 2007-08-31 2013-08-11 Lundbeck & Co As H 兒茶酚胺衍生物和其前藥
WO2009050216A1 (fr) * 2007-10-16 2009-04-23 Dsm Ip Assets Bv Procédé de préparation d'un ester, thioester, alcool ou thiol énantiomériquement et/ou diastéréomériquement enrichi
US9216998B2 (en) 2012-02-15 2015-12-22 Janssen Pharmaceutica Nv Tricyclic indole derivatives useful endothelial lipase inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6127986A (ja) * 1984-07-18 1986-02-07 Sankyo Co Ltd 縮環複素環化合物
JPS61282384A (ja) * 1985-06-10 1986-12-12 Sankyo Co Ltd 縮環複素環化合物の製造法
DE3743824C2 (de) * 1987-12-23 1997-03-06 Hoechst Ag Verfahren zur enzymatischen Racematspaltung von racemischen Alkoholen mit/in Vinylestern durch Umesterung

Also Published As

Publication number Publication date
HUT55016A (en) 1991-04-29
CA2024252A1 (fr) 1991-03-01
EP0674008A1 (fr) 1995-09-27
PT95142A (pt) 1991-05-22
EP0415776A2 (fr) 1991-03-06
PT95142B (pt) 1997-05-28
KR910004624A (ko) 1991-03-29
JPH03163078A (ja) 1991-07-15
IE903127A1 (en) 1991-03-13
CN1050386A (zh) 1991-04-03
HU905707D0 (en) 1991-03-28
EP0415776A3 (en) 1991-10-30
RU2045528C1 (ru) 1995-10-10
HU208012B (en) 1993-07-28

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