DD296082A5 - Verfahren zur herstellung von zwischenprodukten fuer epipodophyllotoxinglucosid-4'-acylderivate - Google Patents
Verfahren zur herstellung von zwischenprodukten fuer epipodophyllotoxinglucosid-4'-acylderivate Download PDFInfo
- Publication number
- DD296082A5 DD296082A5 DD88334711A DD33471188A DD296082A5 DD 296082 A5 DD296082 A5 DD 296082A5 DD 88334711 A DD88334711 A DD 88334711A DD 33471188 A DD33471188 A DD 33471188A DD 296082 A5 DD296082 A5 DD 296082A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- etoposide
- mmol
- added
- methylene chloride
- title compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13512987A | 1987-12-18 | 1987-12-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD296082A5 true DD296082A5 (de) | 1991-11-21 |
Family
ID=22466687
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD88323314A DD283401A5 (de) | 1987-12-18 | 1988-12-16 | Verfahren zur herstellung von epipodophyllotoxinglucosid-4'-acyl-derivaten |
| DD88334711A DD296082A5 (de) | 1987-12-18 | 1988-12-16 | Verfahren zur herstellung von zwischenprodukten fuer epipodophyllotoxinglucosid-4'-acylderivate |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD88323314A DD283401A5 (de) | 1987-12-18 | 1988-12-16 | Verfahren zur herstellung von epipodophyllotoxinglucosid-4'-acyl-derivaten |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0320988A3 (pt) |
| JP (1) | JPH01279896A (pt) |
| KR (1) | KR910008799B1 (pt) |
| CN (1) | CN1033631A (pt) |
| AU (1) | AU616717B2 (pt) |
| CA (1) | CA1312074C (pt) |
| DD (2) | DD283401A5 (pt) |
| DK (1) | DK702688A (pt) |
| FI (1) | FI885785A (pt) |
| HU (1) | HU202548B (pt) |
| MY (1) | MY104067A (pt) |
| NO (1) | NO167668C (pt) |
| NZ (1) | NZ227286A (pt) |
| PT (1) | PT89253B (pt) |
| YU (2) | YU179088A (pt) |
| ZA (2) | ZA886810B (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4868291A (en) * | 1987-08-20 | 1989-09-19 | Bristol-Myers Company | 4'-deshydroxyepipodophyllotoxin glucosides: synthesis and use |
| US4965348A (en) * | 1989-05-19 | 1990-10-23 | Bristol-Myers Company | Dimeric epipodophyllotoxin glucoside derivatives |
| US5036055A (en) * | 1989-06-07 | 1991-07-30 | Bristol-Myers Company | Acylated derivatives of etoposide |
| FR2655047A1 (fr) * | 1989-11-24 | 1991-05-31 | Pf Medicament | Derives d'etoposide, leur preparation et leur application comme intermediaires de synthese. |
| EP0540263A1 (en) * | 1991-10-23 | 1993-05-05 | Cancer Research Campaign Technology Limited | Bacterial nitroreductase for the reduction of CB 1954 and analogues thereof to a cytotoxic form |
| CA2468479C (en) | 2001-12-03 | 2010-04-27 | Universitaetsklinikum Charite Der Humboldt-Universitaet Zu Berlin Technologietransferstelle | Podophyllotoxins as antiproliferative agents |
| GB0421296D0 (en) * | 2004-09-24 | 2004-10-27 | Angiogene Pharm Ltd | Bioreductively-activated prodrugs |
| CN104622809B (zh) * | 2008-05-23 | 2019-04-19 | 英属哥伦比亚大学 | 用于脂质体纳米颗粒的修饰的药物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE546388A (pt) * | ||||
| NL6613143A (pt) * | 1965-09-21 | 1967-03-22 | ||
| DE3374317D1 (en) * | 1982-11-26 | 1987-12-10 | Nippon Kayaku Kk | Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof |
| US4609644A (en) * | 1984-06-15 | 1986-09-02 | St. Jude Children's Research Hospital | Epipodophyllotoxinquinone glucoside derivatives, method of production and use |
| IL77334A (en) * | 1985-12-16 | 1991-04-15 | Univ Bar Ilan | Synthesis of 9-epipodophyllotoxin glucoside derivatives and some novel intermediates therefor |
-
1988
- 1988-09-13 ZA ZA886810A patent/ZA886810B/xx unknown
- 1988-09-23 YU YU01790/88A patent/YU179088A/xx unknown
- 1988-12-12 NZ NZ227286A patent/NZ227286A/en unknown
- 1988-12-12 MY MYPI88001432A patent/MY104067A/en unknown
- 1988-12-14 FI FI885785A patent/FI885785A/fi not_active Application Discontinuation
- 1988-12-15 CN CN88108637A patent/CN1033631A/zh active Pending
- 1988-12-15 NO NO885565A patent/NO167668C/no unknown
- 1988-12-15 ZA ZA889392A patent/ZA889392B/xx unknown
- 1988-12-16 YU YU228388A patent/YU228388A/sh unknown
- 1988-12-16 DD DD88323314A patent/DD283401A5/de unknown
- 1988-12-16 EP EP88121146A patent/EP0320988A3/en not_active Withdrawn
- 1988-12-16 DK DK702688A patent/DK702688A/da not_active Application Discontinuation
- 1988-12-16 HU HU886466A patent/HU202548B/hu not_active IP Right Cessation
- 1988-12-16 DD DD88334711A patent/DD296082A5/de not_active IP Right Cessation
- 1988-12-16 PT PT89253A patent/PT89253B/pt not_active IP Right Cessation
- 1988-12-17 KR KR1019880016897A patent/KR910008799B1/ko not_active IP Right Cessation
- 1988-12-19 JP JP63320316A patent/JPH01279896A/ja active Pending
- 1988-12-19 AU AU27062/88A patent/AU616717B2/en not_active Ceased
- 1988-12-19 CA CA000586374A patent/CA1312074C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1033631A (zh) | 1989-07-05 |
| EP0320988A3 (en) | 1990-08-22 |
| JPH01279896A (ja) | 1989-11-10 |
| AU2706288A (en) | 1989-06-29 |
| NO885565D0 (no) | 1988-12-15 |
| DK702688D0 (da) | 1988-12-16 |
| AU616717B2 (en) | 1991-11-07 |
| DK702688A (da) | 1989-06-19 |
| ZA889392B (en) | 1989-09-27 |
| DD283401A5 (de) | 1990-10-10 |
| ZA886810B (en) | 1989-08-30 |
| FI885785A (fi) | 1989-06-19 |
| FI885785A0 (fi) | 1988-12-14 |
| NO167668C (no) | 1991-11-27 |
| NO167668B (no) | 1991-08-19 |
| KR910008799B1 (ko) | 1991-10-21 |
| YU179088A (en) | 1990-02-28 |
| MY104067A (en) | 1993-11-30 |
| CA1312074C (en) | 1992-12-29 |
| KR890009965A (ko) | 1989-08-05 |
| YU228388A (sh) | 1993-10-20 |
| EP0320988A2 (en) | 1989-06-21 |
| NZ227286A (en) | 1991-08-27 |
| HU202548B (en) | 1991-03-28 |
| NO885565L (no) | 1989-06-19 |
| HUT48641A (en) | 1989-06-28 |
| PT89253B (pt) | 1993-07-30 |
| PT89253A (pt) | 1989-12-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ENJ | Ceased due to non-payment of renewal fee |