DD287495A5 - Verfahren zur herstellung herterozyclischer stickstoffverbindungen - Google Patents

Verfahren zur herstellung herterozyclischer stickstoffverbindungen Download PDF

Info

Publication number
DD287495A5
DD287495A5 DD88312758A DD31275888A DD287495A5 DD 287495 A5 DD287495 A5 DD 287495A5 DD 88312758 A DD88312758 A DD 88312758A DD 31275888 A DD31275888 A DD 31275888A DD 287495 A5 DD287495 A5 DD 287495A5
Authority
DD
German Democratic Republic
Prior art keywords
lower alkyl
carboxy
hydrogen
formula
compound
Prior art date
Application number
DD88312758A
Other languages
German (de)
English (en)
Inventor
Eva Winter-Mihaly
Christian Borel
Andre J Weith
Original Assignee
������@������������k��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ������@������������k�� filed Critical ������@������������k��
Publication of DD287495A5 publication Critical patent/DD287495A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
DD88312758A 1987-02-10 1988-02-08 Verfahren zur herstellung herterozyclischer stickstoffverbindungen DD287495A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878702890A GB8702890D0 (en) 1987-02-10 1987-02-10 Heterocyclic compounds

Publications (1)

Publication Number Publication Date
DD287495A5 true DD287495A5 (de) 1991-02-28

Family

ID=10611962

Family Applications (1)

Application Number Title Priority Date Filing Date
DD88312758A DD287495A5 (de) 1987-02-10 1988-02-08 Verfahren zur herstellung herterozyclischer stickstoffverbindungen

Country Status (13)

Country Link
US (1) US4904675A (no)
EP (1) EP0278908A3 (no)
JP (1) JPS63216872A (no)
AU (1) AU1144888A (no)
DD (1) DD287495A5 (no)
DK (1) DK64788A (no)
FI (1) FI880562A (no)
GB (1) GB8702890D0 (no)
HU (1) HU201015B (no)
NO (1) NO880553L (no)
NZ (1) NZ223443A (no)
YU (1) YU24088A (no)
ZA (1) ZA88894B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4796243A (en) * 1985-06-21 1989-01-03 Nec Corporation Time base correcting apparatus
US5153208A (en) * 1987-02-10 1992-10-06 Hoechst Aktiengesellschaft Pyridine-2,4- and -2,5-dicarboxylic acid amides and their medicinal compositions and methods of use
DE3703963A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben, sowie arzneimittel auf basis dieser verbindungen
US5238948A (en) * 1987-02-10 1993-08-24 Hoechst Aktiengesellschaft Pyridine-2,4- and -2,5-dicarboxylic acid derivatives and medicaments based on these compounds
DE3703959A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeureamide, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
US5512586A (en) * 1987-02-10 1996-04-30 Hoechst Aktiengesellschaft Medicaments based on pyridine-2,4- and 2,5-dicarboxylic acid amides
ATE114305T1 (de) * 1990-03-13 1994-12-15 Hoechst Roussel Pharma 1-alkyl-, 1-alkenyl- und 1-alkynylaryl-2-amino- 1,3-propandiole und verwandte verbindungen, verfahren und zwischenverbindungen zu ihrer herstellung und ihre verwendung als medikamente.
US6046219A (en) * 1995-01-20 2000-04-04 Cornell Research Foundation, Inc. Method for the treatment of conditions mediated by collagen formation together with cell proliferation by application of inhibitors of protein hydroxylation
US5789426A (en) * 1995-01-20 1998-08-04 Cornell Research Foundation, Inc. Method for the treatment of fibroproliferative disorders by application of inhibitors of protein hydroxylation
US5891892A (en) * 1996-10-29 1999-04-06 Warner-Lambert Company Small molecule biaryl compounds as inhibitors of endothelin converting enzyme
ES2384941T3 (es) * 2007-02-16 2012-07-16 Csem Centre Suisse D'electronique Et De Microtechnique Sa - Recherche Et Developpement Método de verificación
US9809586B2 (en) 2015-03-28 2017-11-07 Wisconsin Alumni Research Foundation Inhibitors of collagen prolyl 4-hydroxylase

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3501486A (en) * 1967-04-28 1970-03-17 Ash Stevens Inc Process for the production of 2-pyridine aldoximes
US4404012A (en) * 1980-06-02 1983-09-13 American Cyanamid Company Process for increasing sugar yield in sugarcane
IL62794A0 (en) * 1980-06-02 1981-07-31 American Cyanamid Co Substituted nicotinic acid esters and salts thereof and their use as herbicidal agents
DE3162095D1 (en) * 1980-06-02 1984-03-08 American Cyanamid Co Method to beneficially influence & alter the development & life cycle of agronomic and horticultural crops with certain imidazolinyl nicotinic acids and derivatives thereof
DE3432094A1 (de) * 1984-08-31 1986-03-06 Hoechst Ag, 6230 Frankfurt Ester der pyridin-2,4- und -2,5- dicarbonsaeure als arzneimittel zur inhibierung der prolin- und lysinhydroxylase
GB2174395A (en) * 1986-05-09 1986-11-05 American Cyanimid Co Herbicidal 2-(2-imidazolin-2-yl)pyridine derivatives
JP2561827B2 (ja) * 1987-01-22 1996-12-11 コニカ株式会社 熱カブリの改良された熱現像感光要素

Also Published As

Publication number Publication date
JPS63216872A (ja) 1988-09-09
YU24088A (en) 1990-02-28
FI880562A0 (fi) 1988-02-08
DK64788A (da) 1988-08-11
NO880553L (no) 1988-08-11
HUT46668A (en) 1988-11-28
EP0278908A2 (en) 1988-08-17
US4904675A (en) 1990-02-27
FI880562A (fi) 1988-08-11
EP0278908A3 (en) 1990-01-17
AU1144888A (en) 1988-08-11
DK64788D0 (da) 1988-02-09
HU201015B (en) 1990-09-28
ZA88894B (en) 1988-08-10
NO880553D0 (no) 1988-02-09
GB8702890D0 (en) 1987-03-18
NZ223443A (en) 1990-09-26

Similar Documents

Publication Publication Date Title
DE60225316T2 (de) Cyanoalkylamino-derivate als protease-hemmer
EP1119557B1 (de) Indeno-, naphtho- und benzocyclohepta-dihydrothiazol derivate, deren herstellung und deren verwendung als anorektische arzneimittel
EP0418797B1 (de) Pyrimidin-4,6-dicarbonsäurediamide, Verfahren zu deren Herstellung sowie Verwendung derselben sowie Arzneimittel auf Basis dieser Verbindungen
EP0600949B1 (de) Neue 3,5-di-tert.butyl-4-hydroxyphenyl-derivate, verfahren zu ihrer herstellung und arzneimittel
DE2706977A1 (de) Benzoesaeuren und deren derivate sowie verfahren zu ihrer herstellung
EP0278453A2 (de) Pyridin-2,4- und 2,5-dicarbonsäureamide, Verfahren zu ihrer Herstellung, Verwendung derselben sowie Arzneimittel auf Basis dieser Verbindungen
DD287495A5 (de) Verfahren zur herstellung herterozyclischer stickstoffverbindungen
DE10046029A1 (de) Indazole
EP0408509B1 (de) Substituierte Benzonitrile
DE2838892A1 (de) 2-substituierte-5-hydroxy-1h-imidazol-4-carboxamid-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel
EP0316279A2 (de) Veresterte azacyclische Hydroxyverbindungen
DE3209276A1 (de) Arzneimittel mit antihypoxischer und ischaemie-protektiver wirkung
DD233847A5 (de) Verfahren zur herstellung von methylendiphosphon-derivaten mit antireuhmatischen eigenschaften
DE2824341A1 (de) N- eckige klammer auf 6- eckige klammer auf (aminosulfonyl)phenyl eckige klammer zu -1,2-dihydro-2-oxonicotinyl eckige klammer zu penicilline und -cephalosporine
CH645354A5 (de) Chinolyl-guanidine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mischungen.
EP0530639B1 (de) Heterocyclisch substituierte Chinolylmethoxy-Phenylacetamide als Lipoxygenasehemmer
CH509318A (de) Verfahren zur Herstellung von substituierten Benzimidazolen
DE2812353A1 (de) Oxazol- und thiazol-alkansaeureverbindungen, verfahren zu ihrer herstellung und sie enthaltendes pharmazeutisches mittel
DE4120107A1 (de) Bicyclisch substituierte vinylimidazole, -triazole und -tetrazole
DE2331721A1 (de) Verfahren zur herstellung neuer heterocyclischer verbindungen
DE3804346A1 (de) Tert.-butylphenyl-pyridyl-amide - verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
EP0683159A1 (de) Substituierte Furoxane
DE3034005C2 (de) Indolessigsäure-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zubereitungen
DE102011104267A1 (de) Verbindungen als PPAR beta/delta Inhibitoren für die Behandlung von PPAR beta/delta-vermittelten Erkrankungen
EP0302164A1 (de) Guanidincarbonsäureester, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel