DD284679A5 - Verfahren zur herstellung von adenosin 5'-carboamidderivate - Google Patents
Verfahren zur herstellung von adenosin 5'-carboamidderivate Download PDFInfo
- Publication number
- DD284679A5 DD284679A5 DD88312611A DD31261188A DD284679A5 DD 284679 A5 DD284679 A5 DD 284679A5 DD 88312611 A DD88312611 A DD 88312611A DD 31261188 A DD31261188 A DD 31261188A DD 284679 A5 DD284679 A5 DD 284679A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- group
- lower alkyl
- substituted
- pharmaceutically acceptable
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1116987A | 1987-02-04 | 1987-02-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
DD284679A5 true DD284679A5 (de) | 1990-11-21 |
Family
ID=21749163
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DD88312611A DD284679A5 (de) | 1987-02-04 | 1988-02-02 | Verfahren zur herstellung von adenosin 5'-carboamidderivate |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0277917A3 (hu) |
JP (1) | JPS63201196A (hu) |
KR (1) | KR880009984A (hu) |
AU (1) | AU1123388A (hu) |
DD (1) | DD284679A5 (hu) |
DK (1) | DK54488A (hu) |
FI (1) | FI880405A (hu) |
HU (1) | HU199155B (hu) |
IE (1) | IE880293L (hu) |
NO (1) | NO880469L (hu) |
PT (1) | PT86660B (hu) |
YU (1) | YU20288A (hu) |
ZA (1) | ZA88755B (hu) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4968697A (en) * | 1987-02-04 | 1990-11-06 | Ciba-Geigy Corporation | 2-substituted adenosine 5'-carboxamides as antihypertensive agents |
LU87181A1 (fr) * | 1987-04-06 | 1988-11-17 | Sandoz Sa | Nouveaux derives de l'acide furannuronique,leur preparation et leur utilisation comme medicaments |
GR1000138B (el) * | 1987-04-06 | 1991-09-27 | Sandoz Ag | Νεα παραγωγα ριβοφουρανουρονικου οξεος, μεθοδος δια την παρασευη αυτων και η χρησιμοποιησις αυτων. |
US5034381A (en) * | 1988-01-07 | 1991-07-23 | Ciba-Geigy Corporation | 2-(substituted amino) adenosines as antihypertensives |
AU3820989A (en) * | 1988-08-02 | 1990-02-08 | Ciba-Geigy Ag | 7-amino-3-beta-d-ribofuranosyl-3h-imidazo(4,5-b) pyridin-5-amine derivatives |
US4977144A (en) * | 1988-08-02 | 1990-12-11 | Ciba-Geigy Corporation | Imidazo[4,5-b]pyridine derivatives as cardiovascular agents |
IE882585L (en) * | 1988-08-25 | 1990-02-25 | Prendergast Patrick T | Viral treatment system |
US5312961A (en) * | 1989-02-14 | 1994-05-17 | Elf Sanofi | 2-amino-7-hydroxytetralin carboxylalkyl ethers |
US5140015A (en) * | 1990-02-20 | 1992-08-18 | Whitby Research, Inc. | 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents |
USRE36494E (en) * | 1990-02-20 | 2000-01-11 | Discovery Therapeutics, Inc. | 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents |
US5561134A (en) * | 1990-09-25 | 1996-10-01 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties |
EP0550631B1 (en) * | 1990-09-25 | 1997-01-02 | Rhone-Poulenc Rorer International (Holdings) Inc. | Compounds having antihypertensive and anti-ischemic properties |
US5189027A (en) | 1990-11-30 | 1993-02-23 | Yamasa Shoyu Kabushiki Kaisha | 2-substituted adenosine derivatives and pharmaceutical compositions for circulatory diseases |
EP0499755A1 (fr) * | 1991-02-18 | 1992-08-26 | MIDY S.p.A. | Nouvelles phényléthanolaminotétralines, procédé pour leur préparation, intermédiaires dans ce procédé et compositions pharmaceutiques les contenant |
GB9111580D0 (en) * | 1991-05-30 | 1991-07-24 | Wellcome Found | Nucleoside derivative |
IT1254915B (it) * | 1992-04-24 | 1995-10-11 | Gloria Cristalli | Derivati di adenosina ad attivita' a2 agonista |
GB9301000D0 (en) * | 1993-01-20 | 1993-03-10 | Glaxo Group Ltd | Chemical compounds |
GB9414193D0 (en) * | 1994-07-14 | 1994-08-31 | Glaxo Group Ltd | Compounds |
TW528755B (en) | 1996-12-24 | 2003-04-21 | Glaxo Group Ltd | 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives |
US6110902A (en) * | 1997-06-23 | 2000-08-29 | Moehler; Hanns | Method for the inhibition of neuronal activity leading to a focal epileptic seizure by local delivery of adenosine |
YU44900A (sh) * | 1998-01-31 | 2003-01-31 | Glaxo Group Limited | Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola |
HUP0103025A3 (en) | 1998-06-23 | 2002-04-29 | Glaxo Group Ltd | A2a agonist 2-(purin-9-yl)tetrahydrofuran-3,4-diol derivatives, medicaments containing the same, process for producing them and the useful intermediates |
US7414036B2 (en) | 2002-01-25 | 2008-08-19 | Muscagen Limited | Compounds useful as A3 adenosine receptor agonists |
US20050033044A1 (en) | 2003-05-19 | 2005-02-10 | Bristol-Myers Squibb Pharma Company | Methods for preparing 2-alkynyladenosine derivatives |
AR049384A1 (es) | 2004-05-24 | 2006-07-26 | Glaxo Group Ltd | Derivados de purina |
BRPI0515506A (pt) * | 2004-09-20 | 2008-07-29 | Inotek Pharmaceuticals Corp | derivados de purina e métodos de uso dos mesmos |
GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1019727A (en) * | 1971-03-18 | 1977-10-25 | Abbott Laboratories | Adenosine-5'-carboxylic acid amides |
US4501735A (en) * | 1983-12-05 | 1985-02-26 | Warner-Lambert Company | N6-(1- and 2-benzocycloalkyl) adenosines |
LU87181A1 (fr) * | 1987-04-06 | 1988-11-17 | Sandoz Sa | Nouveaux derives de l'acide furannuronique,leur preparation et leur utilisation comme medicaments |
-
1988
- 1988-01-29 FI FI880405A patent/FI880405A/fi not_active IP Right Cessation
- 1988-01-29 PT PT86660A patent/PT86660B/pt not_active IP Right Cessation
- 1988-01-29 EP EP88810050A patent/EP0277917A3/en not_active Withdrawn
- 1988-02-02 JP JP63021410A patent/JPS63201196A/ja active Pending
- 1988-02-02 YU YU00202/88A patent/YU20288A/xx unknown
- 1988-02-02 DD DD88312611A patent/DD284679A5/de not_active IP Right Cessation
- 1988-02-03 DK DK054488A patent/DK54488A/da not_active Application Discontinuation
- 1988-02-03 HU HU88509A patent/HU199155B/hu not_active IP Right Cessation
- 1988-02-03 AU AU11233/88A patent/AU1123388A/en not_active Abandoned
- 1988-02-03 KR KR1019880000966A patent/KR880009984A/ko not_active Application Discontinuation
- 1988-02-03 ZA ZA88755A patent/ZA88755B/xx unknown
- 1988-02-03 NO NO880469A patent/NO880469L/no unknown
- 1988-02-03 IE IE880293A patent/IE880293L/xx unknown
Also Published As
Publication number | Publication date |
---|---|
PT86660B (pt) | 1992-02-28 |
EP0277917A3 (en) | 1990-03-28 |
DK54488D0 (da) | 1988-02-03 |
JPS63201196A (ja) | 1988-08-19 |
ZA88755B (en) | 1989-10-25 |
NO880469L (no) | 1988-08-05 |
FI880405A (fi) | 1988-08-05 |
EP0277917A2 (en) | 1988-08-10 |
FI880405A0 (fi) | 1988-01-29 |
YU20288A (en) | 1990-04-30 |
KR880009984A (ko) | 1988-10-06 |
HUT46334A (en) | 1988-10-28 |
IE880293L (en) | 1988-08-04 |
NO880469D0 (no) | 1988-02-03 |
DK54488A (da) | 1988-08-05 |
AU1123388A (en) | 1988-08-18 |
HU199155B (en) | 1990-01-29 |
PT86660A (pt) | 1988-02-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DD284679A5 (de) | Verfahren zur herstellung von adenosin 5'-carboamidderivate | |
DE69109631T2 (de) | 2-Substituierte Adenosinderivate und pharmazeutische Zusammensetzungen zur Verwendung gegen Infektionskrankheiten. | |
DE69532195T2 (de) | Benzamidverbindung und ihre medizinische verwendung | |
EP1373265B1 (de) | Substituierte 2, 6-diamino-3, 5-dicyano-4-aryl-pyridine und ihre verwendung als adenosinrezeptor selektive liganden | |
US4968697A (en) | 2-substituted adenosine 5'-carboxamides as antihypertensive agents | |
DE69132389T2 (de) | 2-aralkoxy und 2-alkoxy-adenosinderivate als koronarvasodilatoren und antihypertensive stoffe | |
DD273833A5 (de) | N 9 - cyclopentylsubstituierte adeninderivate | |
EP1368320B1 (de) | Substituierte 2-oxy-3,5-dicyano-4-aryl-6-aminopyridine und ihre verwendung | |
DE60026861T2 (de) | Purin-derivate | |
EP1417173B1 (de) | Substituierte 2-thio-3,5-dicyano-4-phenyl-6-aminopyridine und ihre verwendung als adenosinrezeptor-selektive liganden | |
DE69806919T2 (de) | Antivirale pyrimidin-nukleosid-analogen | |
EP1377569B1 (de) | Substituierte 2-thio-3,5-dicyano-4-phenyl-6-aminopyridine mit adenosinrezeptor-bindender wirkung und ihre verwendung als herz-kreislauf-mittel | |
DE69014351T2 (de) | Pyridincarbonsäureamid-Derivate und diese enthaltende pharmazeutische Zusammensetzungen. | |
DE3215269A1 (de) | Durch eine heterocyklisch-aromatische gruppe n-substituierte, neuartige piperidin-, piperazin- und homopiperazin-derivate, ihr herstellungsverfahren und ihre anwendung in der therapie | |
DE2149249B2 (de) | 4-Amino-6-arylpyrimidine | |
DD283402A5 (de) | Verfahren zur herstellung von 2-substituierten adenosinderivaten | |
DE2918261C2 (hu) | ||
DE68925270T2 (de) | Pyrrolo[3,2-e]pyrazolo[1,5-a]pyrimidinderivate und diese enthaltende Arzneimittel | |
DE69101330T2 (de) | Mit einem heterocyclischen Ring substituierte Cycloalkano[b]dihydroindole und -indolsulfonamide. | |
DE3390162T1 (de) | Desoxyuridinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Pharmazeutika | |
EP1176144B1 (de) | Neue N-Triazolylmethyl-Piperazinderivate als Neurokininrezeptor-Antagonisten | |
DE69719511T2 (de) | Antivirale 2,4-pyrimidindion-derivate und verfahren zu ihrer herstellung | |
DD284025A5 (de) | Verfahren zur herstellung von imidazo(4,5-b)pyridin-derivaten | |
DE2804519C2 (hu) | ||
EP0665228B1 (de) | Neue 3-Phenylsulfonyl-3,7-diazabicyclo(3,3,1)nonan-Verbindungen enthaltende Arzneimittel |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ENJ | Ceased due to non-payment of renewal fee |