DD272998A5 - Verfahren zur herstellung von neuen arzneimitteln mit modifizierter wirkstoffabgabe in form von kuegelchen - Google Patents
Verfahren zur herstellung von neuen arzneimitteln mit modifizierter wirkstoffabgabe in form von kuegelchen Download PDFInfo
- Publication number
- DD272998A5 DD272998A5 DD88319283A DD31928388A DD272998A5 DD 272998 A5 DD272998 A5 DD 272998A5 DD 88319283 A DD88319283 A DD 88319283A DD 31928388 A DD31928388 A DD 31928388A DD 272998 A5 DD272998 A5 DD 272998A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- beads
- drug
- acid
- captopril
- ace inhibitor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4358487A | 1987-04-28 | 1987-04-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
DD272998A5 true DD272998A5 (de) | 1989-11-01 |
Family
ID=21927917
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DD88319283A DD272998A5 (de) | 1987-04-28 | 1988-08-29 | Verfahren zur herstellung von neuen arzneimitteln mit modifizierter wirkstoffabgabe in form von kuegelchen |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0288732A3 (da) |
JP (1) | JPS63284123A (da) |
KR (1) | KR960006060B1 (da) |
AU (1) | AU613898B2 (da) |
CA (1) | CA1323833C (da) |
DD (1) | DD272998A5 (da) |
DK (1) | DK230288A (da) |
HU (1) | HU204694B (da) |
NZ (1) | NZ223713A (da) |
PH (1) | PH26689A (da) |
ZA (1) | ZA881488B (da) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3739690A1 (de) * | 1987-11-24 | 1989-06-08 | Hoechst Ag | Stabilisierte arzneistoffe, verfahren zu ihrer herstellung sowie stabile arzneizubereitungen |
IL88502A (en) * | 1987-12-14 | 1993-04-04 | Squibb & Sons Inc | Pharmaceutical compositions containing an angiotensin converting enzyme inhibitor |
US4966770A (en) * | 1989-07-26 | 1990-10-30 | Himedics, Inc. | Prednisone microencapsulated granules |
CA2039742A1 (en) * | 1990-04-23 | 1991-10-24 | Andrew B. Dennis | Tablet composition and method for problem pharmaceutical materials |
DE4109134A1 (de) * | 1991-03-20 | 1992-09-24 | Knoll Ag | Erzeugnisse, enthaltend verapamil und trandolapril |
GB2258613B (en) * | 1991-08-12 | 1996-01-10 | Euro Celtique Sa | Pharmaceutical diltiazem formulation |
KR100221695B1 (ko) * | 1991-08-12 | 1999-09-15 | 그린 마틴, 브라이언 쥐 테슬리 | 약학적 구상 제형 |
GB9117361D0 (en) * | 1991-08-12 | 1991-09-25 | Euro Celtique Sa | Oral dosage form |
DE69231499T2 (de) * | 1991-12-30 | 2001-05-03 | Fmc Corp | Zusammensetzung auf der basis von mikrokristalliner zellulose für die herstellung von kugelförmigen teilchen |
DE69311394T2 (de) * | 1992-02-20 | 1997-10-30 | Euro Celtique Sa | Arzneimittel verzögerter Wirkstoffabgabe |
US6162802A (en) * | 1992-03-10 | 2000-12-19 | Papa; Joseph | Synergistic combination therapy using benazepril and amlodipine for the treatment of cardiovascular disorders and compositions therefor |
DE59209706D1 (de) * | 1992-12-01 | 1999-07-08 | Spirig Ag | S(+)-Ibuprofen enthaltende Arzneimittel |
TW483763B (en) * | 1994-09-02 | 2002-04-21 | Astra Ab | Pharmaceutical composition comprising of ramipril and dihydropyridine compound |
WO2000022909A2 (en) * | 1998-10-19 | 2000-04-27 | Biotech Australia Pty. Limited | Systems for oral delivery |
GB2374874A (en) * | 2001-04-11 | 2002-10-30 | Bioprogress Tech Int Inc | Modified cellulose films |
FR2824477B1 (fr) * | 2001-05-09 | 2005-09-09 | Ethypharm Lab Prod Ethiques | Granules enrobes a base d'inhibiteur de l'enzyme de conversion de l'anfiotensine, leur procede de preparation et comprimes orodispersibles contenant les granules enrobes |
WO2003094899A1 (es) * | 2002-05-09 | 2003-11-20 | Diffucap-Chemobras Química E Farmacéutica, Ltda. | Nuevo procedimiento para la preparacion de composiciones de liberacion programada conteniendo (s) -1- [n-[1-(ethoxycarbonyl)-3-phenylpropyl]-l-alanyl]-l-proline, y al producto obtenido por dicho procedimiento |
US6869963B2 (en) * | 2003-07-11 | 2005-03-22 | Sandoz Ag | Stable pharmaceutical compositions containing an ACE inhibitor |
RU2382637C2 (ru) * | 2004-04-30 | 2010-02-27 | Астеллас Фарма Инк. | Фармацевтическая композиция для перорального введения в форме частиц с рассчитанным временем высвобождения и быстро распадающиеся таблетки, содержащие указанную композицию |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4217347A (en) * | 1977-12-27 | 1980-08-12 | E. R. Squibb & Sons, Inc. | Method of treating hypertension and medicaments therefor |
NZ196349A (en) * | 1980-03-07 | 1984-08-24 | Interx Research Corp | Enhancement of absorption rate of orally administered polar bioactive agents |
JPS6056122B2 (ja) * | 1980-05-21 | 1985-12-09 | 塩野義製薬株式会社 | 徐放性製剤 |
DE3124090A1 (de) * | 1981-06-19 | 1983-01-05 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue orale dipyridamolformen |
DE3237575A1 (de) * | 1982-10-09 | 1984-04-12 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue orale mopidamolformen |
IE55745B1 (en) * | 1983-04-06 | 1991-01-02 | Elan Corp Plc | Sustained absorption pharmaceutical composition |
PH18946A (en) * | 1983-04-21 | 1985-11-14 | Elan Corp Plc | Controlled absorption pharmaceutical composition |
IE56999B1 (en) * | 1983-12-22 | 1992-03-11 | Elan Corp Plc | Pharmaceutical formulation |
JPS60262919A (ja) * | 1984-06-11 | 1985-12-26 | Kawasaki Steel Corp | 一方向性珪素鋼のスラブ加熱方法 |
JPS61125687A (ja) * | 1984-11-22 | 1986-06-13 | Hitachi Ltd | パタ−ン抽出方式 |
US5188840A (en) * | 1985-09-26 | 1993-02-23 | Chugai Seiyaku Kabushiki Kaisha | Slow-release pharmaceutical agent |
JPH0617254B2 (ja) * | 1986-05-28 | 1994-03-09 | 日産化学工業株式会社 | 硬化コンクリ−トの劣化防止方法 |
-
1988
- 1988-02-26 CA CA000559971A patent/CA1323833C/en not_active Expired - Fee Related
- 1988-03-02 NZ NZ223713A patent/NZ223713A/xx unknown
- 1988-03-02 ZA ZA881488A patent/ZA881488B/xx unknown
- 1988-03-07 PH PH36599A patent/PH26689A/en unknown
- 1988-03-09 AU AU12835/88A patent/AU613898B2/en not_active Ceased
- 1988-03-21 EP EP19880104478 patent/EP0288732A3/en not_active Withdrawn
- 1988-04-27 DK DK230288A patent/DK230288A/da unknown
- 1988-04-27 HU HU882129A patent/HU204694B/hu not_active IP Right Cessation
- 1988-04-27 KR KR1019880004771A patent/KR960006060B1/ko not_active IP Right Cessation
- 1988-04-28 JP JP63107500A patent/JPS63284123A/ja active Pending
- 1988-08-29 DD DD88319283A patent/DD272998A5/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ZA881488B (en) | 1988-08-22 |
JPS63284123A (ja) | 1988-11-21 |
DK230288D0 (da) | 1988-04-27 |
EP0288732A3 (en) | 1990-11-07 |
KR960006060B1 (ko) | 1996-05-08 |
CA1323833C (en) | 1993-11-02 |
NZ223713A (en) | 1990-06-26 |
DK230288A (da) | 1988-10-29 |
KR880012215A (ko) | 1988-11-26 |
HU204694B (en) | 1992-02-28 |
AU613898B2 (en) | 1991-08-15 |
HUT52944A (en) | 1990-09-28 |
AU1283588A (en) | 1988-11-03 |
PH26689A (en) | 1992-09-15 |
EP0288732A2 (en) | 1988-11-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ENJ | Ceased due to non-payment of renewal fee |