DD260494A5 - Verfahren zur herstellung von alpha-hydroxythiotherm - Google Patents

Verfahren zur herstellung von alpha-hydroxythiotherm Download PDF

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Publication number
DD260494A5
DD260494A5 DD86297075A DD29707586A DD260494A5 DD 260494 A5 DD260494 A5 DD 260494A5 DD 86297075 A DD86297075 A DD 86297075A DD 29707586 A DD29707586 A DD 29707586A DD 260494 A5 DD260494 A5 DD 260494A5
Authority
DD
German Democratic Republic
Prior art keywords
formula
compound
acid
group
radical
Prior art date
Application number
DD86297075A
Other languages
German (de)
English (en)
Inventor
Andreas Beck
Werner Breitenstein
Andreas Von Sprecher
Robert W Lang
Konrad Oertle
Original Assignee
����`��@���k��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ����`��@���k�� filed Critical ����`��@���k��
Publication of DD260494A5 publication Critical patent/DD260494A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DD86297075A 1985-12-06 1986-12-04 Verfahren zur herstellung von alpha-hydroxythiotherm DD260494A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH522885 1985-12-06

Publications (1)

Publication Number Publication Date
DD260494A5 true DD260494A5 (de) 1988-09-28

Family

ID=4290092

Family Applications (1)

Application Number Title Priority Date Filing Date
DD86297075A DD260494A5 (de) 1985-12-06 1986-12-04 Verfahren zur herstellung von alpha-hydroxythiotherm

Country Status (17)

Country Link
US (1) US4808572A (xx)
EP (1) EP0225602B1 (xx)
JP (1) JPS62138465A (xx)
AT (1) ATE68177T1 (xx)
AU (1) AU6613886A (xx)
CA (1) CA1303294C (xx)
DD (1) DD260494A5 (xx)
DE (1) DE3681890D1 (xx)
DK (1) DK586186A (xx)
ES (1) ES2040205T3 (xx)
FI (1) FI864901A (xx)
GR (1) GR3003066T3 (xx)
HU (1) HU196173B (xx)
IL (1) IL80866A0 (xx)
NO (1) NO864896L (xx)
PT (1) PT83868B (xx)
ZA (1) ZA869213B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5149717A (en) * 1988-03-29 1992-09-22 Ciba-Geigy Corporation Alkanophenones useful for treating allergies
FR2648814B1 (fr) * 1989-06-26 1991-10-18 Lafon Labor L'alpha (tert-butyl-aminomethyl-3,4-dichlorobenzyl)thioacetamide, son procede de preparation et son application en therapeutique
EP0419410A3 (en) * 1989-09-19 1991-08-14 Ciba-Geigy Ag Alkanophenones
DE59410387D1 (de) * 1993-01-29 2004-10-21 Ticona Gmbh Faserverstärktes Cycloolefincopolymer-Material, Verfahren zu seiner Herstellung und Formkörper aus dem Material
WO2005047230A1 (en) * 2003-11-13 2005-05-26 The University Of Sydney Bis-cationic compounds and use thereof
WO2007022718A1 (en) * 2005-08-25 2007-03-01 Chunde Liu Alkyl aryl alkyl alcohols, their derivations and preparation process thereof
US8735627B2 (en) 2010-10-28 2014-05-27 Mapi Pharma Ltd. Intermediate compounds and process for the preparation of fingolimod
CN102850319A (zh) * 2011-06-27 2013-01-02 中国药科大学 一种制备{5-[2-(4-正辛基苯基)乙基]-2,2-二甲基-1,3-二氧六环-5-基}氨基甲酸叔丁酯的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE12241T1 (de) * 1981-03-03 1985-04-15 Lilly Industries Ltd Leukotrienaehnliche verbindungen, deren herstellung und verwendung in pharmazeutischen zusammensetzungen.
US4513005A (en) * 1981-06-18 1985-04-23 Lilly Industries Limited SRS-A antagonists
US4461775A (en) * 1982-08-02 1984-07-24 Mcneilab, Inc. Hydroxythioether fatty acid derivatives
US4533747A (en) * 1983-03-07 1985-08-06 Smithkline Beckman Corporation Leukotriene antagonists intermediates
DK130984A (da) * 1983-03-07 1984-09-08 Smithkline Beckman Corp Leukotrien-antagonister
US4552893A (en) * 1983-03-07 1985-11-12 Smithkline Beckman Corporation Leukotriene antagonists
EP0123543B1 (en) * 1983-04-21 1988-02-03 Merck Frosst Canada Inc. Leukotriene antagonists, their production and use and compositions containing them
EP0170048B1 (de) * 1984-06-28 1991-04-17 Ciba-Geigy Ag Aliphatische Thioether

Also Published As

Publication number Publication date
FI864901A (fi) 1987-06-07
DK586186D0 (da) 1986-12-05
NO864896L (no) 1987-06-09
DK586186A (da) 1987-06-07
DE3681890D1 (en) 1991-11-14
AU6613886A (en) 1987-06-11
PT83868A (en) 1987-01-01
EP0225602A3 (en) 1989-06-14
EP0225602A2 (de) 1987-06-16
IL80866A0 (en) 1987-03-31
NO864896D0 (no) 1986-12-05
US4808572A (en) 1989-02-28
HU196173B (en) 1988-10-28
ZA869213B (en) 1987-07-29
FI864901A0 (fi) 1986-12-01
JPS62138465A (ja) 1987-06-22
HUT43560A (en) 1987-11-30
ATE68177T1 (de) 1991-10-15
EP0225602B1 (de) 1991-10-09
GR3003066T3 (en) 1993-02-17
CA1303294C (en) 1992-06-09
ES2040205T3 (es) 1993-10-16
PT83868B (pt) 1989-07-31

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