DD227029A3 - Enzymelektrode zur glukosemessung - Google Patents
Enzymelektrode zur glukosemessung Download PDFInfo
- Publication number
- DD227029A3 DD227029A3 DD23981582A DD23981582A DD227029A3 DD 227029 A3 DD227029 A3 DD 227029A3 DD 23981582 A DD23981582 A DD 23981582A DD 23981582 A DD23981582 A DD 23981582A DD 227029 A3 DD227029 A3 DD 227029A3
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- glucose
- membrane
- enzyme
- electrode
- blood
- Prior art date
Links
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title claims abstract description 43
- 239000008103 glucose Substances 0.000 title claims abstract description 43
- 108090000790 Enzymes Proteins 0.000 title claims abstract description 36
- 102000004190 Enzymes Human genes 0.000 title claims abstract description 36
- 238000005259 measurement Methods 0.000 title claims abstract description 8
- 239000012528 membrane Substances 0.000 claims abstract description 36
- 239000008280 blood Substances 0.000 claims abstract description 16
- 210000004369 blood Anatomy 0.000 claims abstract description 16
- 230000002209 hydrophobic effect Effects 0.000 claims abstract description 12
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 6
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 6
- 239000001301 oxygen Substances 0.000 claims abstract description 6
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims abstract description 3
- 239000000126 substance Substances 0.000 claims abstract description 3
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims abstract 3
- 229940125396 insulin Drugs 0.000 claims abstract 2
- 238000000926 separation method Methods 0.000 claims abstract 2
- 210000000227 basophil cell of anterior lobe of hypophysis Anatomy 0.000 claims 3
- 239000000523 sample Substances 0.000 claims 3
- 238000011088 calibration curve Methods 0.000 claims 2
- 238000010790 dilution Methods 0.000 claims 2
- 239000012895 dilution Substances 0.000 claims 2
- 208000002249 Diabetes Complications Diseases 0.000 claims 1
- 206010012655 Diabetic complications Diseases 0.000 claims 1
- 230000000052 comparative effect Effects 0.000 claims 1
- 238000010276 construction Methods 0.000 claims 1
- 230000003345 hyperglycaemic effect Effects 0.000 claims 1
- 230000002218 hypoglycaemic effect Effects 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 238000011144 upstream manufacturing Methods 0.000 claims 1
- 238000009792 diffusion process Methods 0.000 abstract description 8
- 102000004877 Insulin Human genes 0.000 abstract 1
- 108090001061 Insulin Proteins 0.000 abstract 1
- 210000003719 b-lymphocyte Anatomy 0.000 abstract 1
- 238000001802 infusion Methods 0.000 abstract 1
- 229940088598 enzyme Drugs 0.000 description 12
- 108010015776 Glucose oxidase Proteins 0.000 description 2
- 239000004366 Glucose oxidase Substances 0.000 description 2
- 229940116332 glucose oxidase Drugs 0.000 description 2
- 235000019420 glucose oxidase Nutrition 0.000 description 2
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 229920002301 cellulose acetate Polymers 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- -1 polyethylene Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 230000009993 protective function Effects 0.000 description 1
- 230000007306 turnover Effects 0.000 description 1
Landscapes
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DD23981582A DD227029A3 (de) | 1982-05-13 | 1982-05-13 | Enzymelektrode zur glukosemessung |
| BG6049083A BG42633A1 (en) | 1982-05-13 | 1983-04-08 | Enzymic electrode for measuring glucose content |
| CS832656A CS265683A1 (en) | 1982-05-13 | 1983-04-13 | Enzymova elektroda k mereni glukozy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DD23981582A DD227029A3 (de) | 1982-05-13 | 1982-05-13 | Enzymelektrode zur glukosemessung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD227029A3 true DD227029A3 (de) | 1985-09-04 |
Family
ID=5538548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD23981582A DD227029A3 (de) | 1982-05-13 | 1982-05-13 | Enzymelektrode zur glukosemessung |
Country Status (3)
| Country | Link |
|---|---|
| BG (1) | BG42633A1 (cs) |
| CS (1) | CS265683A1 (cs) |
| DD (1) | DD227029A3 (cs) |
Cited By (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0327018A3 (en) * | 1988-02-05 | 1990-04-11 | Nova Biomedical Corporation | Enzyme electrode |
| DE4104776A1 (de) * | 1990-08-31 | 1992-03-05 | Inst Molekularbiologie Ak | Sandwich-enzymmembran fuer enzymelektroden und -optoden zur bestimmung von substraten, verfahren zu ihrer herstellung und ihre verwendung |
| US5183550A (en) * | 1989-06-30 | 1993-02-02 | Dragerwerk Aktiengesellschaft | Measuring cell for electrochemically detecting a gas |
| US5352348A (en) * | 1987-04-09 | 1994-10-04 | Nova Biomedical Corporation | Method of using enzyme electrode |
| EP0778897A4 (en) * | 1994-09-01 | 2000-03-22 | Adam Heller | SUBCUTANEOUS GLUCOSE MONITORING ELECTRODE |
| DE4221848C2 (de) * | 1992-07-03 | 2001-04-12 | Eckhard Salzsieder | Verfahren und Anordnung zur selbsttätigen in situ Kalibrierung von intrakorporalen Glukosemeßeinrichtungen |
| US6484046B1 (en) | 1998-03-04 | 2002-11-19 | Therasense, Inc. | Electrochemical analyte sensor |
| US6576101B1 (en) | 1997-02-06 | 2003-06-10 | Therasense, Inc. | Small volume in vitro analyte sensor |
| US6591125B1 (en) | 2000-06-27 | 2003-07-08 | Therasense, Inc. | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator |
| US6592745B1 (en) | 1998-10-08 | 2003-07-15 | Therasense, Inc. | Method of using a small volume in vitro analyte sensor with diffusible or non-leachable redox mediator |
| US6975893B2 (en) | 1999-06-18 | 2005-12-13 | Therasense, Inc. | Mass transport limited in vivo analyte sensor |
| US7861397B2 (en) | 1998-03-04 | 2011-01-04 | Abbott Diabetes Care Inc. | Method of making an electrochemical sensor |
| US8175673B2 (en) | 1998-04-30 | 2012-05-08 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8668645B2 (en) | 2001-01-02 | 2014-03-11 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8688188B2 (en) | 1998-04-30 | 2014-04-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US9625413B2 (en) | 2006-03-31 | 2017-04-18 | Abbott Diabetes Care Inc. | Analyte monitoring devices and methods therefor |
| US9668684B2 (en) | 2009-02-26 | 2017-06-06 | Abbott Diabetes Care Inc. | Self-powered analyte sensor |
| US9669162B2 (en) | 2005-11-04 | 2017-06-06 | Abbott Diabetes Care Inc. | Method and system for providing basal profile modification in analyte monitoring and management systems |
| US9743863B2 (en) | 2006-03-31 | 2017-08-29 | Abbott Diabetes Care Inc. | Method and system for powering an electronic device |
| US9801545B2 (en) | 2007-03-01 | 2017-10-31 | Abbott Diabetes Care Inc. | Method and apparatus for providing rolling data in communication systems |
| US9962091B2 (en) | 2002-12-31 | 2018-05-08 | Abbott Diabetes Care Inc. | Continuous glucose monitoring system and methods of use |
| US9980670B2 (en) | 2002-11-05 | 2018-05-29 | Abbott Diabetes Care Inc. | Sensor inserter assembly |
| US10231654B2 (en) | 2005-11-01 | 2019-03-19 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| DE102017126732A1 (de) * | 2017-11-14 | 2019-05-16 | Endress+Hauser Conducta Gmbh+Co. Kg | Sensormembran, Sensor, ein Messgerät umfassend den Sensor und Verwendung des Sensors |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10009467A1 (de) * | 2000-02-28 | 2001-09-20 | Bcs Bio Und Chemosensoren Gmbh | Enzymatisch-elektrochemische Durchflußmeßeinrichtung (EED) |
-
1982
- 1982-05-13 DD DD23981582A patent/DD227029A3/de not_active IP Right Cessation
-
1983
- 1983-04-08 BG BG6049083A patent/BG42633A1/xx unknown
- 1983-04-13 CS CS832656A patent/CS265683A1/cs unknown
Cited By (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5352348A (en) * | 1987-04-09 | 1994-10-04 | Nova Biomedical Corporation | Method of using enzyme electrode |
| EP0327018A3 (en) * | 1988-02-05 | 1990-04-11 | Nova Biomedical Corporation | Enzyme electrode |
| US5183550A (en) * | 1989-06-30 | 1993-02-02 | Dragerwerk Aktiengesellschaft | Measuring cell for electrochemically detecting a gas |
| DE4104776A1 (de) * | 1990-08-31 | 1992-03-05 | Inst Molekularbiologie Ak | Sandwich-enzymmembran fuer enzymelektroden und -optoden zur bestimmung von substraten, verfahren zu ihrer herstellung und ihre verwendung |
| US6514718B2 (en) | 1991-03-04 | 2003-02-04 | Therasense, Inc. | Subcutaneous glucose electrode |
| DE4221848C2 (de) * | 1992-07-03 | 2001-04-12 | Eckhard Salzsieder | Verfahren und Anordnung zur selbsttätigen in situ Kalibrierung von intrakorporalen Glukosemeßeinrichtungen |
| EP0778897A4 (en) * | 1994-09-01 | 2000-03-22 | Adam Heller | SUBCUTANEOUS GLUCOSE MONITORING ELECTRODE |
| US7988845B2 (en) | 1997-02-06 | 2011-08-02 | Abbott Diabetes Care Inc. | Integrated lancing and measurement device and analyte measuring methods |
| US8118992B2 (en) | 1997-02-06 | 2012-02-21 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US6576101B1 (en) | 1997-02-06 | 2003-06-10 | Therasense, Inc. | Small volume in vitro analyte sensor |
| US8105476B2 (en) | 1997-02-06 | 2012-01-31 | Abbott Diabetes Care Inc. | Integrated lancing and measurement device |
| US7861397B2 (en) | 1998-03-04 | 2011-01-04 | Abbott Diabetes Care Inc. | Method of making an electrochemical sensor |
| US6484046B1 (en) | 1998-03-04 | 2002-11-19 | Therasense, Inc. | Electrochemical analyte sensor |
| US8666469B2 (en) | 1998-04-30 | 2014-03-04 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8688188B2 (en) | 1998-04-30 | 2014-04-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8391945B2 (en) | 1998-04-30 | 2013-03-05 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8175673B2 (en) | 1998-04-30 | 2012-05-08 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8641619B2 (en) | 1998-04-30 | 2014-02-04 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8226555B2 (en) | 1998-04-30 | 2012-07-24 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8235896B2 (en) | 1998-04-30 | 2012-08-07 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8372005B2 (en) | 1998-04-30 | 2013-02-12 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US6592745B1 (en) | 1998-10-08 | 2003-07-15 | Therasense, Inc. | Method of using a small volume in vitro analyte sensor with diffusible or non-leachable redox mediator |
| US9891185B2 (en) | 1998-10-08 | 2018-02-13 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US8226815B2 (en) | 1998-10-08 | 2012-07-24 | Abbott Diabetes Care Inc. | Small volume in vitro sensor and methods of making |
| US8701282B2 (en) | 1998-10-08 | 2014-04-22 | Abbott Diabetes Care Inc. | Method for manufacturing a biosensor |
| US6975893B2 (en) | 1999-06-18 | 2005-12-13 | Therasense, Inc. | Mass transport limited in vivo analyte sensor |
| US6591125B1 (en) | 2000-06-27 | 2003-07-08 | Therasense, Inc. | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator |
| US9662057B2 (en) | 2000-06-27 | 2017-05-30 | Abbott Diabetes Care Inc. | Integrated sample acquisition and analyte measurement method |
| US8668645B2 (en) | 2001-01-02 | 2014-03-11 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US9610034B2 (en) | 2001-01-02 | 2017-04-04 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US9980670B2 (en) | 2002-11-05 | 2018-05-29 | Abbott Diabetes Care Inc. | Sensor inserter assembly |
| US9962091B2 (en) | 2002-12-31 | 2018-05-08 | Abbott Diabetes Care Inc. | Continuous glucose monitoring system and methods of use |
| US10201301B2 (en) | 2005-11-01 | 2019-02-12 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US10231654B2 (en) | 2005-11-01 | 2019-03-19 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US11272867B2 (en) | 2005-11-01 | 2022-03-15 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US9669162B2 (en) | 2005-11-04 | 2017-06-06 | Abbott Diabetes Care Inc. | Method and system for providing basal profile modification in analyte monitoring and management systems |
| US9743863B2 (en) | 2006-03-31 | 2017-08-29 | Abbott Diabetes Care Inc. | Method and system for powering an electronic device |
| US9625413B2 (en) | 2006-03-31 | 2017-04-18 | Abbott Diabetes Care Inc. | Analyte monitoring devices and methods therefor |
| US9801545B2 (en) | 2007-03-01 | 2017-10-31 | Abbott Diabetes Care Inc. | Method and apparatus for providing rolling data in communication systems |
| US9668684B2 (en) | 2009-02-26 | 2017-06-06 | Abbott Diabetes Care Inc. | Self-powered analyte sensor |
| DE102017126732A1 (de) * | 2017-11-14 | 2019-05-16 | Endress+Hauser Conducta Gmbh+Co. Kg | Sensormembran, Sensor, ein Messgerät umfassend den Sensor und Verwendung des Sensors |
Also Published As
| Publication number | Publication date |
|---|---|
| CS265683A1 (en) | 1985-06-13 |
| BG42633A1 (en) | 1988-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RPI | Change in the person, name or address of the patentee (searches according to art. 11 and 12 extension act) | ||
| RPV | Change in the person, the name or the address of the representative (searches according to art. 11 and 12 extension act) | ||
| UW | Conversion of economic patent into exclusive patent | ||
| ENJ | Ceased due to non-payment of renewal fee |