DD216026A5 - Verfahren zur herstellung von cephemderivaten - Google Patents

Verfahren zur herstellung von cephemderivaten Download PDF

Info

Publication number
DD216026A5
DD216026A5 DD83258350A DD25835083A DD216026A5 DD 216026 A5 DD216026 A5 DD 216026A5 DD 83258350 A DD83258350 A DD 83258350A DD 25835083 A DD25835083 A DD 25835083A DD 216026 A5 DD216026 A5 DD 216026A5
Authority
DD
German Democratic Republic
Prior art keywords
group
alkyl
hydrogen
isoquinoline
quinoline
Prior art date
Application number
DD83258350A
Other languages
German (de)
English (en)
Inventor
Rudolf Lattrell
Walter Duerckheimer
Reiner Kirrstetter
Wilfried Schwab
Norbert Klesel
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DD216026A5 publication Critical patent/DD216026A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Rigid Pipes And Flexible Pipes (AREA)
DD83258350A 1982-12-23 1983-12-21 Verfahren zur herstellung von cephemderivaten DD216026A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823247614 DE3247614A1 (de) 1982-12-23 1982-12-23 Cephalosporinderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
DD216026A5 true DD216026A5 (de) 1984-11-28

Family

ID=6181485

Family Applications (1)

Application Number Title Priority Date Filing Date
DD83258350A DD216026A5 (de) 1982-12-23 1983-12-21 Verfahren zur herstellung von cephemderivaten

Country Status (19)

Country Link
EP (1) EP0111935B1 (enrdf_load_html_response)
JP (1) JPS59130294A (enrdf_load_html_response)
KR (1) KR840007015A (enrdf_load_html_response)
AT (1) ATE37881T1 (enrdf_load_html_response)
AU (1) AU2280983A (enrdf_load_html_response)
CS (1) CS249132B2 (enrdf_load_html_response)
DD (1) DD216026A5 (enrdf_load_html_response)
DE (2) DE3247614A1 (enrdf_load_html_response)
DK (1) DK594383A (enrdf_load_html_response)
ES (1) ES528247A0 (enrdf_load_html_response)
FI (1) FI834710A7 (enrdf_load_html_response)
GR (1) GR81360B (enrdf_load_html_response)
HU (1) HU189792B (enrdf_load_html_response)
IL (1) IL70519A0 (enrdf_load_html_response)
NO (1) NO834775L (enrdf_load_html_response)
NZ (1) NZ206659A (enrdf_load_html_response)
PH (1) PH20088A (enrdf_load_html_response)
PT (1) PT77877B (enrdf_load_html_response)
ZA (1) ZA839526B (enrdf_load_html_response)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK500285A (da) * 1984-11-02 1986-05-03 Glaxo Group Ltd Cephalosporinantibiotika
CA1267647A (en) * 1984-12-27 1990-04-10 Ryosuke Ushijima Cephalosporin derivatives
NO166283C (no) * 1985-03-01 1991-06-26 Takeda Chemical Industries Ltd Analogifremgangsmaate for fremstilling av terapeutisk aktive 7beta-(2-(5-amino-1,2,4-tiadiazol-3-yl)-2(z)-substituertoksyiminoacetamido)-3-(heterocyclylmetyl)-3-cefem-4-karboksylsyrederivater.
GB2183630A (en) * 1985-10-31 1987-06-10 Glaxo Group Ltd Cephalosporin antibiotics
EP0238060B1 (en) * 1986-03-19 1992-01-08 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, processes for their preparation and antibacterial agents
JPH0645631B2 (ja) * 1986-03-19 1994-06-15 萬有製薬株式会社 新規セフアロスポリン誘導体
US4814328A (en) * 1986-03-19 1989-03-21 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, and antibacterial agents
WO1988005776A1 (en) * 1987-02-02 1988-08-11 Teijin Limited Cephalosporin compounds or their salts, process for their preparation, and parmaceutical compositions
AU1228988A (en) * 1987-02-03 1988-08-24 Teijin Limited Cephalosporin compounds or their salts, process for their preparation, and pharmaceutical compositions
DE3910421A1 (de) * 1989-03-31 1990-10-04 Hoechst Ag Polare cephalosporinderivate und verfahren zu ihrer herstellung
TW200305422A (en) 2002-03-18 2003-11-01 Shionogi & Co Broad spectrum cefem compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2715385A1 (de) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
US4396619A (en) * 1981-09-08 1983-08-02 Eli Lilly And Company Cephalosporin betaines
US4396620A (en) * 1981-09-08 1983-08-02 Eli Lilly And Company Cephalosporin quinolinium betaines
US4450270A (en) * 1981-10-02 1984-05-22 Eli Lilly And Company Dioximino cephalosporin antibiotics
US4402955A (en) * 1981-10-02 1983-09-06 Eli Lilly And Company Dioximino cephalosporin antibiotics

Also Published As

Publication number Publication date
DE3378212D1 (en) 1988-11-17
ES8406494A1 (es) 1984-08-01
GR81360B (enrdf_load_html_response) 1984-12-11
NO834775L (no) 1984-06-25
EP0111935B1 (de) 1988-10-12
AU2280983A (en) 1984-06-28
DE3247614A1 (de) 1984-07-05
PT77877A (de) 1984-01-01
HU189792B (en) 1986-07-28
DK594383A (da) 1984-06-24
ATE37881T1 (de) 1988-10-15
PH20088A (en) 1986-09-24
FI834710A7 (fi) 1984-06-24
JPS59130294A (ja) 1984-07-26
CS249132B2 (en) 1987-03-12
HUT34036A (en) 1985-01-28
PT77877B (de) 1986-04-21
ES528247A0 (es) 1984-08-01
KR840007015A (ko) 1984-12-04
DK594383D0 (da) 1983-12-22
ZA839526B (en) 1984-08-29
IL70519A0 (en) 1984-03-30
EP0111935A2 (de) 1984-06-27
NZ206659A (en) 1986-11-12
EP0111935A3 (en) 1985-07-03
FI834710A0 (fi) 1983-12-21

Similar Documents

Publication Publication Date Title
EP0064740B1 (de) Cephalosporinderivate und Verfahren zu ihrer Herstellung
US4833134A (en) Cephem compounds
EP0088320B1 (de) Cephalosporinderivate und Verfahren zu ihrer Herstellung
EP0034760B1 (de) Cephalosporinderivate, sie enthaltende pharmazeutische Präparate und Verfahren zu ihrer Herstellung
US4500526A (en) Cephalosporin derivatives
EP0137440A2 (de) Cephalosporinderivate und Verfahren zu ihrer Herstellung
DE3233376A1 (de) Cephalosporinchinoliniumbetaine und sie enthaltende pharmazeutische mittel
EP0137441A2 (de) Cephalosporinderivate und Verfahren zu ihrer Herstellung
DE3307550C2 (enrdf_load_html_response)
EP0111934B1 (de) Cephalosporinderivate und Verfahren zu ihrer Herstellung
DD216026A5 (de) Verfahren zur herstellung von cephemderivaten
DE3586547T2 (de) Antibakterielle verbindungen.
EP0137442A2 (de) Cephalosporinderivate und Verfahren zu ihrer Herstellung
EP0135142B1 (de) Cephalosporinderivate und Verfahren zu ihrer Herstellung
DE3650157T2 (de) Cephalosporin-verbindungen.
EP0222322B1 (de) Cephalosporinderivate und Verfahren zu ihrer Herstellung
KR100377559B1 (ko) 경구투여 가능한 세팔로스포린계 화합물 및 이의 제조방법
EP0390099B1 (de) Polare Cephalosporinderivate und Verfahren zu ihrer Herstellung
DE3923541A1 (de) Cephalosporinderivate und verfahren zu ihrer herstellung
AT384613B (de) Verfahren zur herstellung von neuen cephalosporinderivaten
AT389701B (de) Neue cephalosporinverbindungen und diese enthaltende pharmazeutische zusammensetzungen
CA1117522A (en) Cephalosporin esters
EP0604920A1 (en) Novel cephalosporin compounds
EP0281092A2 (de) Cephalosporinderivate und Verfahren zu ihrer Herstellung
DD215786A5 (de) Verfahren zur herstellung von bevorzugten infrarot- und funkmesstarnmitteln