DD202009A5 - Verfahren zur herstellung von 1-(substituierten phenylthiokarbamyl)-3,3-disubstituierten formamidinen - Google Patents

Verfahren zur herstellung von 1-(substituierten phenylthiokarbamyl)-3,3-disubstituierten formamidinen Download PDF

Info

Publication number
DD202009A5
DD202009A5 DD81233897A DD23389781A DD202009A5 DD 202009 A5 DD202009 A5 DD 202009A5 DD 81233897 A DD81233897 A DD 81233897A DD 23389781 A DD23389781 A DD 23389781A DD 202009 A5 DD202009 A5 DD 202009A5
Authority
DD
German Democratic Republic
Prior art keywords
carbon atoms
methyl
compounds
preparation
alkyl
Prior art date
Application number
DD81233897A
Other languages
German (de)
English (en)
Inventor
Ferenc M Pallos
Eugene G Teach
Jack R Debaun
Original Assignee
Stauffer Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to NO813044A priority Critical patent/NO149844C/no
Priority to CA000385557A priority patent/CA1177850A/en
Priority to DK405581A priority patent/DK405581A/da
Priority to AU75277/81A priority patent/AU7527781A/en
Priority to FI812899A priority patent/FI812899L/fi
Priority to ZA816456A priority patent/ZA816456B/xx
Priority to EP81304274A priority patent/EP0075047A1/en
Priority to PT73758A priority patent/PT73758B/pt
Priority to JP56154919A priority patent/JPS5867663A/ja
Application filed by Stauffer Chemical Co filed Critical Stauffer Chemical Co
Priority to DD81233897A priority patent/DD202009A5/de
Publication of DD202009A5 publication Critical patent/DD202009A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/195—Radicals derived from nitrogen analogues of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DD81233897A 1981-09-08 1981-10-05 Verfahren zur herstellung von 1-(substituierten phenylthiokarbamyl)-3,3-disubstituierten formamidinen DD202009A5 (de)

Priority Applications (10)

Application Number Priority Date Filing Date Title
NO813044A NO149844C (no) 1981-09-08 1981-09-08 Analogifremgangsmaate for fremstilling av terapeutisk aktive fenyltiokarbamyl-formamidin-derivater
CA000385557A CA1177850A (en) 1981-09-08 1981-09-10 1-(substituted phenylthiocarbamyl) 3,3-disubstituted formamidines and their use as pharmaceutical agents
DK405581A DK405581A (da) 1981-09-08 1981-09-11 1-(substitueret phenylthiocarbamyl)-3,3-disubstituerede formamidiner og deres anvendelse som farmaceutiske midler
AU75277/81A AU7527781A (en) 1981-09-08 1981-09-16 1-(substituted phenylthiocarbamyl)o8o-disubstituted formamidines
FI812899A FI812899L (fi) 1981-09-08 1981-09-16 1-(substituerad fenyltiokarbamyl) 3,3-disubstituerade formamidiner och deras anvaendning saosom farmaceutiska aemnen
ZA816456A ZA816456B (en) 1981-09-08 1981-09-17 1-(substituted phenylthiocarbamyl)3,3-disubstituted formamidines and their use as pharmaceutical agents.
EP81304274A EP0075047A1 (en) 1981-09-08 1981-09-17 1-(Substituted phenylthiocarbamyl) 3,3-disubstituted formamidines and their production and pharmaceutical compositions containing them
PT73758A PT73758B (en) 1981-09-08 1981-10-01 Process for preparing 1-(substituted phenyltiocarbamyl)3,3- -disubstituted formamidines
JP56154919A JPS5867663A (ja) 1981-09-08 1981-10-01 １−（置換フエニルチオカルバミル）３，３−２置換ホルムアミジン類およびその薬剤としての利用
DD81233897A DD202009A5 (de) 1981-09-08 1981-10-05 Verfahren zur herstellung von 1-(substituierten phenylthiokarbamyl)-3,3-disubstituierten formamidinen

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
NO813044A NO149844C (no) 1981-09-08 1981-09-08 Analogifremgangsmaate for fremstilling av terapeutisk aktive fenyltiokarbamyl-formamidin-derivater
CA000385557A CA1177850A (en) 1981-09-08 1981-09-10 1-(substituted phenylthiocarbamyl) 3,3-disubstituted formamidines and their use as pharmaceutical agents
DK405581A DK405581A (da) 1981-09-08 1981-09-11 1-(substitueret phenylthiocarbamyl)-3,3-disubstituerede formamidiner og deres anvendelse som farmaceutiske midler
AU75277/81A AU7527781A (en) 1981-09-08 1981-09-16 1-(substituted phenylthiocarbamyl)o8o-disubstituted formamidines
FI812899A FI812899L (fi) 1981-09-08 1981-09-16 1-(substituerad fenyltiokarbamyl) 3,3-disubstituerade formamidiner och deras anvaendning saosom farmaceutiska aemnen
ZA816456A ZA816456B (en) 1981-09-08 1981-09-17 1-(substituted phenylthiocarbamyl)3,3-disubstituted formamidines and their use as pharmaceutical agents.
EP81304274A EP0075047A1 (en) 1981-09-08 1981-09-17 1-(Substituted phenylthiocarbamyl) 3,3-disubstituted formamidines and their production and pharmaceutical compositions containing them
PT73758A PT73758B (en) 1981-09-08 1981-10-01 Process for preparing 1-(substituted phenyltiocarbamyl)3,3- -disubstituted formamidines
JP56154919A JPS5867663A (ja) 1981-09-08 1981-10-01 １−（置換フエニルチオカルバミル）３，３−２置換ホルムアミジン類およびその薬剤としての利用
DD81233897A DD202009A5 (de) 1981-09-08 1981-10-05 Verfahren zur herstellung von 1-(substituierten phenylthiokarbamyl)-3,3-disubstituierten formamidinen

Publications (1)

Publication Number Publication Date
DD202009A5 true DD202009A5 (de) 1983-08-24

Family

ID=32601270

Family Applications (1)

Application Number Title Priority Date Filing Date
DD81233897A DD202009A5 (de) 1981-09-08 1981-10-05 Verfahren zur herstellung von 1-(substituierten phenylthiokarbamyl)-3,3-disubstituierten formamidinen

Country Status (10)

Country Link
EP (1) EP0075047A1 (fi)
JP (1) JPS5867663A (fi)
AU (1) AU7527781A (fi)
CA (1) CA1177850A (fi)
DD (1) DD202009A5 (fi)
DK (1) DK405581A (fi)
FI (1) FI812899L (fi)
NO (1) NO149844C (fi)
PT (1) PT73758B (fi)
ZA (1) ZA816456B (fi)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3959368A (en) * 1975-04-28 1976-05-25 Stauffer Chemical Company N,N-dimethyl-N'-phenylthiocarbamyl formamidine and its use as an anti-inflammatory agent
US4012527A (en) * 1975-09-15 1977-03-15 Stauffer Chemical Company N,N-Dimethyl-N'-phenylthiocarbamyl formamidine hydrochloride and its use as an anti-inflammatory agent

Also Published As

Publication number Publication date
JPS5867663A (ja) 1983-04-22
DK405581A (da) 1983-03-12
FI812899L (fi) 1983-03-17
CA1177850A (en) 1984-11-13
AU7527781A (en) 1983-03-24
NO149844B (no) 1984-03-26
PT73758A (en) 1981-11-01
NO813044L (no) 1983-03-09
ZA816456B (en) 1982-11-24
PT73758B (en) 1983-03-29
EP0075047A1 (en) 1983-03-30
NO149844C (no) 1984-07-04

Similar Documents

Publication Publication Date Title
AT363096B (de) Verfahren zur herstellung von neuen phthalazinderivaten und deren salzen
DE2354389C2 (de) 2-(4-Acyl-homopiperazino)-4-amino-6,7-dimethoxy-chinazolin-Verbindungen und Verfahren zu ihrer Herstellung
DE2345064C3 (de) 4-Amino-2-<l,2r3,4-tetrahydroisochinolin-2 yl)-chinazolinderivate und diese enthaltende Arzneimittel
DE2105490A1 (de) Imidazolderivate, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DD202152A5 (de) Verfahren zur herstellung von phenylpiperazinderivaten
CH635823A5 (de) Verfahren zur herstellung von neuen 1-amidin-3-substituierten-phenylharnstoffen.
DE2322880C2 (de) 4-(Imidazolin-2-ylamino)-2,1,3-benzothiadiazole und Verfahren zu deren Herstellung
CH460041A (de) Verfahren zur Herstellung von 4-substituierten 4'-tert.-Aminoalkoxyphenylen
DE2449205C2 (de) Substituierte Furylverbindungen, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2757532A1 (de) N,n'-disubstituiertes cyclisches diamin und verfahren zu dessen herstellung
DE2807381A1 (de) Pharmazeutische zusammensetzung mit einem gehalt an einem 1,3,5-triazin- 2,6-dion
DE2427272C3 (de) 1-(2-(β-Naphthyloxy)-äthyl)-3-methyl -pyrazolon-(5), Verfahren sowie Verwendung als Antithrombotikum
DE3879378T2 (de) Amid-verbindungen.
DD202009A5 (de) Verfahren zur herstellung von 1-(substituierten phenylthiokarbamyl)-3,3-disubstituierten formamidinen
DE2907379A1 (de) Benzylidenderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE3247454A1 (de) Substituierte 3-phenyl-5-methyl-isoxazol-4-carboxy-anilide, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
CH667457A5 (de) Verfahren zur herstellung von substituierten 7-oxomitosanen.
DE1770289A1 (de) 5H-Dibenzo(c,g)(1,2,6)thiadiazocin-6,6-dioxyde und Verfahren zu deren Herstellung
DE2046577A1 (de) Neue Pyrimidopyndazinderivate und Verfahren zu ihrer Herstellung
DE2354931C2 (de) trans-2-Phenylbicyclooctan-Verbindungen, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zubereitungen
DE2703522C2 (fi)
DE2253748A1 (de) Carboxamidobenzoesaeuren
DE2101691A1 (de) Isochinolinderivate
DE3113087A1 (de) Verfahren zur herstellung von piperazin-derivaten und damit in zusammenhang stehende pharmazeutische ansaetze
DE2151487A1 (de) Pharmazeutische Massen