ZA816456B - 1-(substituted phenylthiocarbamyl)3,3-disubstituted formamidines and their use as pharmaceutical agents. - Google Patents

1-(substituted phenylthiocarbamyl)3,3-disubstituted formamidines and their use as pharmaceutical agents.

Info

Publication number
ZA816456B
ZA816456B ZA816456A ZA816456A ZA816456B ZA 816456 B ZA816456 B ZA 816456B ZA 816456 A ZA816456 A ZA 816456A ZA 816456 A ZA816456 A ZA 816456A ZA 816456 B ZA816456 B ZA 816456B
Authority
ZA
South Africa
Prior art keywords
phenylthiocarbamyl
substituted
pharmaceutical agents
formamidines
disubstituted
Prior art date
Application number
ZA816456A
Other languages
English (en)
Inventor
F Pallos
E Teach
J Debaun
Original Assignee
Stauffer Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to NO813044A priority Critical patent/NO149844C/no
Priority to CA000385557A priority patent/CA1177850A/en
Priority to DK405581A priority patent/DK405581A/da
Priority to AU75277/81A priority patent/AU7527781A/en
Priority to FI812899A priority patent/FI812899L/fi
Application filed by Stauffer Chemical Co filed Critical Stauffer Chemical Co
Priority to ZA816456A priority patent/ZA816456B/xx
Priority to EP81304274A priority patent/EP0075047A1/en
Priority to PT73758A priority patent/PT73758B/pt
Priority to JP56154919A priority patent/JPS5867663A/ja
Priority to DD81233897A priority patent/DD202009A5/de
Publication of ZA816456B publication Critical patent/ZA816456B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/195—Radicals derived from nitrogen analogues of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA816456A 1981-09-08 1981-09-17 1-(substituted phenylthiocarbamyl)3,3-disubstituted formamidines and their use as pharmaceutical agents. ZA816456B (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
NO813044A NO149844C (no) 1981-09-08 1981-09-08 Analogifremgangsmaate for fremstilling av terapeutisk aktive fenyltiokarbamyl-formamidin-derivater
CA000385557A CA1177850A (en) 1981-09-08 1981-09-10 1-(substituted phenylthiocarbamyl) 3,3-disubstituted formamidines and their use as pharmaceutical agents
DK405581A DK405581A (da) 1981-09-08 1981-09-11 1-(substitueret phenylthiocarbamyl)-3,3-disubstituerede formamidiner og deres anvendelse som farmaceutiske midler
AU75277/81A AU7527781A (en) 1981-09-08 1981-09-16 1-(substituted phenylthiocarbamyl)o8o-disubstituted formamidines
FI812899A FI812899L (fi) 1981-09-08 1981-09-16 1-(substituerad fenyltiokarbamyl) 3,3-disubstituerade formamidiner och deras anvaendning saosom farmaceutiska aemnen
ZA816456A ZA816456B (en) 1981-09-08 1981-09-17 1-(substituted phenylthiocarbamyl)3,3-disubstituted formamidines and their use as pharmaceutical agents.
EP81304274A EP0075047A1 (en) 1981-09-08 1981-09-17 1-(Substituted phenylthiocarbamyl) 3,3-disubstituted formamidines and their production and pharmaceutical compositions containing them
PT73758A PT73758B (en) 1981-09-08 1981-10-01 Process for preparing 1-(substituted phenyltiocarbamyl)3,3- -disubstituted formamidines
JP56154919A JPS5867663A (ja) 1981-09-08 1981-10-01 １−（置換フエニルチオカルバミル）３，３−２置換ホルムアミジン類およびその薬剤としての利用
DD81233897A DD202009A5 (de) 1981-09-08 1981-10-05 Verfahren zur herstellung von 1-(substituierten phenylthiokarbamyl)-3,3-disubstituierten formamidinen

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
NO813044A NO149844C (no) 1981-09-08 1981-09-08 Analogifremgangsmaate for fremstilling av terapeutisk aktive fenyltiokarbamyl-formamidin-derivater
CA000385557A CA1177850A (en) 1981-09-08 1981-09-10 1-(substituted phenylthiocarbamyl) 3,3-disubstituted formamidines and their use as pharmaceutical agents
DK405581A DK405581A (da) 1981-09-08 1981-09-11 1-(substitueret phenylthiocarbamyl)-3,3-disubstituerede formamidiner og deres anvendelse som farmaceutiske midler
AU75277/81A AU7527781A (en) 1981-09-08 1981-09-16 1-(substituted phenylthiocarbamyl)o8o-disubstituted formamidines
FI812899A FI812899L (fi) 1981-09-08 1981-09-16 1-(substituerad fenyltiokarbamyl) 3,3-disubstituerade formamidiner och deras anvaendning saosom farmaceutiska aemnen
ZA816456A ZA816456B (en) 1981-09-08 1981-09-17 1-(substituted phenylthiocarbamyl)3,3-disubstituted formamidines and their use as pharmaceutical agents.
EP81304274A EP0075047A1 (en) 1981-09-08 1981-09-17 1-(Substituted phenylthiocarbamyl) 3,3-disubstituted formamidines and their production and pharmaceutical compositions containing them
PT73758A PT73758B (en) 1981-09-08 1981-10-01 Process for preparing 1-(substituted phenyltiocarbamyl)3,3- -disubstituted formamidines
JP56154919A JPS5867663A (ja) 1981-09-08 1981-10-01 １−（置換フエニルチオカルバミル）３，３−２置換ホルムアミジン類およびその薬剤としての利用
DD81233897A DD202009A5 (de) 1981-09-08 1981-10-05 Verfahren zur herstellung von 1-(substituierten phenylthiokarbamyl)-3,3-disubstituierten formamidinen

Publications (1)

Publication Number Publication Date
ZA816456B true ZA816456B (en) 1982-11-24

Family

ID=32601270

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA816456A ZA816456B (en) 1981-09-08 1981-09-17 1-(substituted phenylthiocarbamyl)3,3-disubstituted formamidines and their use as pharmaceutical agents.

Country Status (10)

Country Link
EP (1) EP0075047A1 (fi)
JP (1) JPS5867663A (fi)
AU (1) AU7527781A (fi)
CA (1) CA1177850A (fi)
DD (1) DD202009A5 (fi)
DK (1) DK405581A (fi)
FI (1) FI812899L (fi)
NO (1) NO149844C (fi)
PT (1) PT73758B (fi)
ZA (1) ZA816456B (fi)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3959368A (en) * 1975-04-28 1976-05-25 Stauffer Chemical Company N,N-dimethyl-N'-phenylthiocarbamyl formamidine and its use as an anti-inflammatory agent
US4012527A (en) * 1975-09-15 1977-03-15 Stauffer Chemical Company N,N-Dimethyl-N'-phenylthiocarbamyl formamidine hydrochloride and its use as an anti-inflammatory agent

Also Published As

Publication number Publication date
JPS5867663A (ja) 1983-04-22
DK405581A (da) 1983-03-12
FI812899L (fi) 1983-03-17
CA1177850A (en) 1984-11-13
AU7527781A (en) 1983-03-24
NO149844B (no) 1984-03-26
PT73758A (en) 1981-11-01
NO813044L (no) 1983-03-09
PT73758B (en) 1983-03-29
EP0075047A1 (en) 1983-03-30
NO149844C (no) 1984-07-04
DD202009A5 (de) 1983-08-24

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