DD145538A5 - Verfahren zur herstellung von bicyclischen thia-diaza-verbindungen - Google Patents
Verfahren zur herstellung von bicyclischen thia-diaza-verbindungen Download PDFInfo
- Publication number
- DD145538A5 DD145538A5 DD78214990A DD21499078A DD145538A5 DD 145538 A5 DD145538 A5 DD 145538A5 DD 78214990 A DD78214990 A DD 78214990A DD 21499078 A DD21499078 A DD 21499078A DD 145538 A5 DD145538 A5 DD 145538A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- salts
- items
- compounds
- produces
- imidazo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/18—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
- C07D279/06—1,3-Thiazines; Hydrogenated 1,3-thiazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU77703A LU77703A1 (de) | 1977-07-07 | 1977-07-07 | Verfahren zur herstellung von bicyclischen thia-diaza-verbindungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD145538A5 true DD145538A5 (de) | 1980-12-17 |
Family
ID=19728633
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD78206565A DD138212A5 (de) | 1977-07-07 | 1978-07-06 | Verfahren zur herstellung von bicyclischen thia-diaza-verbindungen |
| DD78214990A DD145538A5 (de) | 1977-07-07 | 1978-07-06 | Verfahren zur herstellung von bicyclischen thia-diaza-verbindungen |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD78206565A DD138212A5 (de) | 1977-07-07 | 1978-07-06 | Verfahren zur herstellung von bicyclischen thia-diaza-verbindungen |
Country Status (18)
| Country | Link |
|---|---|
| EP (3) | EP0019688A1 (ru) |
| JP (1) | JPS5416470A (ru) |
| AR (2) | AR222309A1 (ru) |
| AU (1) | AU3778878A (ru) |
| DD (2) | DD138212A5 (ru) |
| DK (1) | DK305578A (ru) |
| ES (4) | ES471458A1 (ru) |
| FI (1) | FI782132A (ru) |
| GR (1) | GR64978B (ru) |
| IL (1) | IL55086A0 (ru) |
| IT (1) | IT8149647A0 (ru) |
| LU (1) | LU77703A1 (ru) |
| NO (1) | NO782357L (ru) |
| NZ (1) | NZ187789A (ru) |
| PL (1) | PL116596B1 (ru) |
| PT (1) | PT68246A (ru) |
| SU (4) | SU873886A3 (ru) |
| ZA (1) | ZA783898B (ru) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CY1302A (en) * | 1978-04-11 | 1985-12-06 | Ciba Geigy Ag | Mercapto-imidazole derivatives,their preparation,their pharmaceutical compositions and applications |
| DE2823197A1 (de) * | 1978-05-24 | 1979-11-29 | Schering Ag | Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
| US4175127A (en) * | 1978-09-27 | 1979-11-20 | Smithkline Corporation | Pyridyl substituted 2,3-dihydroimidazo[2,1-b]thiazoles |
| PL221188A1 (ru) * | 1979-01-05 | 1980-12-01 | Ciba Geigy Ag | |
| US4636516A (en) * | 1981-02-19 | 1987-01-13 | Yamanouchi Pharmaceutical Co., Ltd. | 3,5-di-tert-butyl-4-hydroxyphenyl-substituted heterocyclic compounds |
| US5008390A (en) * | 1985-05-23 | 1991-04-16 | Smithkline Beckman Corporation | Compounds for preparing 6-phenyl-2,3-dihydroimidazo[2,1-b]-thiazoles and corresponding thiazines |
| US4803279A (en) * | 1985-05-23 | 1989-02-07 | Smithkline Beckman Corporation | 1.4-dihydro-4-pyridyl-substituted imidazo (2,1-b) thiazoles and the corresponding thiazines. |
| IL78834A (en) * | 1985-05-23 | 1992-07-15 | Smithkline Beckman Corp | 2,3-dihydro-5-(1,4-dihydropyridin-4-yl)-6-phenylimidazo(2,1-b)thiazoles and 6,7-dihydro-3-(1,4-dihydropyridin-4-yl)-2-phenyl-5h-imidazo(2,1-b)(1,3)thiazines and their use as intermediates in a process for preparing the corresponding pyridyl-substituted imidazo(2,1-b)thiazoles and 5h-imidazo(2,1-b)(1,3)thiazines |
| US4719218A (en) * | 1985-12-12 | 1988-01-12 | Smithkline Beckman Corporation | Pyrrolo[1,2-a]imidazole and pyrrolo[1,2-a]pyridine derivatives and their use as 5-lipoxygenase pathway inhibitor |
| ZW24186A1 (en) * | 1985-12-12 | 1987-07-08 | Smithkline Beckman Corp | Inhibition of the 5-lipoxygenase pathway |
| AU6355190A (en) * | 1989-06-13 | 1991-01-17 | Smithkline Beecham Corporation | Inhibition of interleukin-1 and tumor necrosis factor production by monocytes and/or macrophages |
| GB9005966D0 (en) * | 1990-03-16 | 1990-05-09 | May & Baker Ltd | New compositions of matter |
| GB9019838D0 (en) * | 1990-09-11 | 1990-10-24 | Smith Kline French Lab | Compounds |
| US5240918A (en) * | 1992-03-24 | 1993-08-31 | Egis Gyogyszergyar | 2-(substituted imino)-thiazolidines and process for the preparation thereof |
| US5552422A (en) * | 1995-01-11 | 1996-09-03 | Merck Frosst Canada, Inc. | Aryl substituted 5,5 fused aromatic nitrogen compounds as anti-inflammatory agents |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2981739A (en) * | 1958-01-27 | 1961-04-25 | Diamond Alkali Co | Certain alpha-haloaldehyde addition products of ethylenethioureas and process |
| NL131034C (ru) * | 1964-05-11 | |||
| US3297708A (en) * | 1965-10-06 | 1967-01-10 | American Cyanamid Co | Method of preparing thiazolidines |
| US3455924A (en) * | 1967-02-08 | 1969-07-15 | Upjohn Co | Dianisylimidazoles |
| NL164285C (nl) * | 1968-01-09 | 1980-12-15 | Rhone Poulenc Sa | Werkwijze ter bereiding van een farmaceutisch preparaat, dat een imidazoÿ2.1-bÿthiazoolderivaat bevat, de gevormde farmaceutische preparaten, alsmede werkwijze voor het bereiden van dit imidazoÿ2.1-bÿthiazoolderivaat. |
| BE788792A (fr) * | 1971-09-30 | 1973-03-13 | Ici Ltd | Procedes et compositions a usage anti-bacterien |
| US3842097A (en) * | 1973-01-22 | 1974-10-15 | Searle & Co | 2-(phenoxyalkylthio)imidazoles and congeners |
| SE428686B (sv) * | 1975-08-11 | 1983-07-18 | Du Pont | Forfarande for framstellning av antiinflammatoriskt aktiva imidazoler |
| GB1541321A (en) * | 1976-03-10 | 1979-02-28 | Metabio | 2,3-dihydroimidazo(2,1-b)thiazole derivatives and process for their preparation |
| US4064260A (en) * | 1976-07-29 | 1977-12-20 | E. I. Du Pont De Nemours And Company | Anti-inflammatory diarylimidazothiazoles and their corresponding S-oxides |
| US4263311A (en) * | 1976-09-27 | 1981-04-21 | Smithkline Corporation | 5,6-Phenyl-2,3-dihydroimidazo [2,1-b] thiazoles |
-
1977
- 1977-07-07 LU LU77703A patent/LU77703A1/de unknown
-
1978
- 1978-06-29 EP EP80101323A patent/EP0019688A1/de not_active Ceased
- 1978-06-29 EP EP78100272A patent/EP0000353A3/xx not_active Withdrawn
- 1978-06-29 EP EP80101322A patent/EP0020858A1/de not_active Withdrawn
- 1978-07-03 FI FI782132A patent/FI782132A/fi not_active Application Discontinuation
- 1978-07-03 PT PT68246A patent/PT68246A/pt unknown
- 1978-07-05 AR AR272843A patent/AR222309A1/es active
- 1978-07-05 IL IL55086A patent/IL55086A0/xx unknown
- 1978-07-05 GR GR56695A patent/GR64978B/el unknown
- 1978-07-05 ES ES471458A patent/ES471458A1/es not_active Expired
- 1978-07-05 AU AU37788/78A patent/AU3778878A/en active Pending
- 1978-07-06 DD DD78206565A patent/DD138212A5/xx unknown
- 1978-07-06 ZA ZA00783898A patent/ZA783898B/xx unknown
- 1978-07-06 JP JP8153378A patent/JPS5416470A/ja active Pending
- 1978-07-06 NO NO782357A patent/NO782357L/no unknown
- 1978-07-06 SU SU782632647A patent/SU873886A3/ru active
- 1978-07-06 NZ NZ187789A patent/NZ187789A/xx unknown
- 1978-07-06 DD DD78214990A patent/DD145538A5/de unknown
- 1978-07-06 DK DK783055A patent/DK305578A/da unknown
- 1978-07-07 PL PL1978208253A patent/PL116596B1/pl unknown
-
1979
- 1979-03-05 ES ES478296A patent/ES478296A1/es not_active Expired
- 1979-05-18 SU SU792763599A patent/SU893134A3/ru active
- 1979-09-10 ES ES484033A patent/ES484033A1/es not_active Expired
- 1979-09-20 ES ES484327A patent/ES484327A1/es not_active Expired
- 1979-10-23 SU SU792831085A patent/SU850007A3/ru active
- 1979-12-03 AR AR279136A patent/AR224381A1/es active
- 1979-12-20 SU SU792855458A patent/SU873887A3/ru active
-
1981
- 1981-11-06 IT IT8149647A patent/IT8149647A0/it unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0020858A1 (de) | 1981-01-07 |
| ZA783898B (en) | 1979-07-25 |
| SU873887A3 (ru) | 1981-10-15 |
| ES478296A1 (es) | 1979-05-16 |
| AR224381A1 (es) | 1981-11-30 |
| FI782132A (fi) | 1979-01-08 |
| PL208253A1 (pl) | 1979-06-04 |
| JPS5416470A (en) | 1979-02-07 |
| SU873886A3 (ru) | 1981-10-15 |
| IT8149647A0 (it) | 1981-11-06 |
| EP0000353A2 (de) | 1979-01-24 |
| ES484327A1 (es) | 1980-05-16 |
| ES484033A1 (es) | 1980-04-16 |
| GR64978B (en) | 1980-06-11 |
| IL55086A0 (en) | 1978-09-29 |
| AR222309A1 (es) | 1981-05-15 |
| PT68246A (en) | 1978-08-01 |
| SU893134A3 (ru) | 1981-12-23 |
| NZ187789A (en) | 1981-03-16 |
| EP0019688A1 (de) | 1980-12-10 |
| NO782357L (no) | 1979-01-09 |
| SU850007A3 (ru) | 1981-07-23 |
| EP0000353A3 (en) | 1979-06-13 |
| PL116596B1 (en) | 1981-06-30 |
| DD138212A5 (de) | 1979-10-17 |
| ES471458A1 (es) | 1979-10-01 |
| DK305578A (da) | 1979-01-08 |
| LU77703A1 (de) | 1979-03-26 |
| AU3778878A (en) | 1980-01-10 |
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