DD142804A3 - Verfahren zur herstellung von na-alkyl-bzw.na-aryl-sulfonylierten omega-amidinophenyl-alpha-aminoalkylcarbonsaeureamiden - Google Patents

Verfahren zur herstellung von na-alkyl-bzw.na-aryl-sulfonylierten omega-amidinophenyl-alpha-aminoalkylcarbonsaeureamiden Download PDF

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Publication number
DD142804A3
DD142804A3 DD77201898A DD20189877A DD142804A3 DD 142804 A3 DD142804 A3 DD 142804A3 DD 77201898 A DD77201898 A DD 77201898A DD 20189877 A DD20189877 A DD 20189877A DD 142804 A3 DD142804 A3 DD 142804A3
Authority
DD
German Democratic Republic
Prior art keywords
alkyl
acid
converted
reaction
substituted
Prior art date
Application number
DD77201898A
Other languages
German (de)
English (en)
Inventor
Guenther Wagner
Peter Richter
Heidemarie Horn
Bernd Voigt
Helmut Vieweg
Fritz Markwardt
Peter Walsmann
Hans-Georg Kazmirowski
Hellmut Landmann
Joerg Stuerzebecher
Joerg Hauptmann
Ingrid Lischke
Original Assignee
Wagner Guenter
Peter Richter
Heidemarie Horn
Bernd Voigt
Helmut Vieweg
Fritz Markwardt
Peter Walsmann
Kazmirowski Hans Georg
Hellmut Landmann
Joerg Stuerzebecher
Joerg Hauptmann
Ingrid Lischke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wagner Guenter, Peter Richter, Heidemarie Horn, Bernd Voigt, Helmut Vieweg, Fritz Markwardt, Peter Walsmann, Kazmirowski Hans Georg, Hellmut Landmann, Joerg Stuerzebecher, Joerg Hauptmann, Ingrid Lischke filed Critical Wagner Guenter
Priority to DD77201898A priority Critical patent/DD142804A3/de
Priority to DE19782845941 priority patent/DE2845941A1/de
Priority to SE7811454A priority patent/SE7811454L/xx
Priority to GB7843320A priority patent/GB2007663A/en
Priority to FR7831496A priority patent/FR2407915A1/fr
Priority to JP13720578A priority patent/JPS54106448A/ja
Publication of DD142804A3 publication Critical patent/DD142804A3/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
DD77201898A 1977-11-07 1977-11-07 Verfahren zur herstellung von na-alkyl-bzw.na-aryl-sulfonylierten omega-amidinophenyl-alpha-aminoalkylcarbonsaeureamiden DD142804A3 (de)

Priority Applications (6)

Application Number Priority Date Filing Date Title
DD77201898A DD142804A3 (de) 1977-11-07 1977-11-07 Verfahren zur herstellung von na-alkyl-bzw.na-aryl-sulfonylierten omega-amidinophenyl-alpha-aminoalkylcarbonsaeureamiden
DE19782845941 DE2845941A1 (de) 1977-11-07 1978-10-21 N alpha-alkylsulfonylierte bzw. n alpha-arylsulfonylierte omega- amidinophenyl-alpha-amino-alkylcarbonsaeureamide, ihre saeureadditionssalze und verfahren zu ihrer herstellung
SE7811454A SE7811454L (sv) 1977-11-07 1978-11-06 Forfarande for framstellning av n-alfa-alkyl-resp n-alfa-arylsulfonylerade omega-amidinofenyl-alfa-aminoalkylkarbonsyraamider
GB7843320A GB2007663A (en) 1977-11-07 1978-11-06 Sulphonylated omega - amidinophenyl- alpha -aminocarhoxylic acid amides
FR7831496A FR2407915A1 (fr) 1977-11-07 1978-11-07 Nouveaux o-amidinophenyl-a-aminoalcoyl-carboxamides na-alcoylsulfonyles et na-arylsulfonyles, procedes pour leur preparation et leurs utilisations therapeutiques
JP13720578A JPS54106448A (en) 1977-11-07 1978-11-07 N alphaaalkylsulfonyl omegaaamidinophenyll alphaaaminoalkyl carboxylic acid amide and n alphaaamidinophenyllalphaaaminoalkyl carboxilic amide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DD77201898A DD142804A3 (de) 1977-11-07 1977-11-07 Verfahren zur herstellung von na-alkyl-bzw.na-aryl-sulfonylierten omega-amidinophenyl-alpha-aminoalkylcarbonsaeureamiden

Publications (1)

Publication Number Publication Date
DD142804A3 true DD142804A3 (de) 1980-07-16

Family

ID=5510339

Family Applications (1)

Application Number Title Priority Date Filing Date
DD77201898A DD142804A3 (de) 1977-11-07 1977-11-07 Verfahren zur herstellung von na-alkyl-bzw.na-aryl-sulfonylierten omega-amidinophenyl-alpha-aminoalkylcarbonsaeureamiden

Country Status (6)

Country Link
JP (1) JPS54106448A (fr)
DD (1) DD142804A3 (fr)
DE (1) DE2845941A1 (fr)
FR (1) FR2407915A1 (fr)
GB (1) GB2007663A (fr)
SE (1) SE7811454L (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2005741C (fr) * 1988-12-26 1998-06-02 Hiroyoshi Hidaka Sulfonoaminoquinolines ayant une activite de relaxation des muscles lisses des vaisseaux
US5245034A (en) * 1988-12-26 1993-09-14 Kiroyoshi Hidaka Compound having vessel smooth muscle relaxation activity
US5084466A (en) * 1989-01-31 1992-01-28 Hoffmann-La Roche Inc. Novel carboxamide pyridine compounds which have useful pharmaceutical utility
US5256812A (en) * 1989-01-31 1993-10-26 Hoffmann-La Roche Inc. Carboxamides and sulfonamides
EP0511347A1 (fr) * 1990-11-15 1992-11-04 Pentapharm A.G. Derives de la phenylalanine metasubstitues
US5424334A (en) * 1991-12-19 1995-06-13 G. D. Searle & Co. Peptide mimetic compounds useful as platelet aggregation inhibitors
PH31294A (en) * 1992-02-13 1998-07-06 Thomae Gmbh Dr K Benzimidazolyl derivatives, pharmaceutical compositions containing these compounds and process for preparing them.
DE4326465A1 (de) * 1993-01-20 1995-02-09 Thomae Gmbh Dr K Aminosäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
ATE223392T1 (de) * 1993-02-10 2002-09-15 Pentapharm Ag Piperazide von substituierten phenylalanin- derivativen als thrombin inhibitoren
AU3107795A (en) * 1994-08-09 1996-03-07 Pentapharm Ag Inhibitors of the benzamidine type
KR0173034B1 (ko) * 1995-04-28 1999-03-30 성재갑 선택적 트롬빈 억제제
GB9621814D0 (en) * 1996-10-19 1996-12-11 British Biotech Pharm Metalloproteinase inhibitors
JP3853653B2 (ja) 1999-08-07 2006-12-06 ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト カルボン酸アミド、その調製法及び医薬組成物としてのその使用
MXPA03006648A (es) * 2001-02-02 2003-10-15 Boehringer Ingelheim Pharma Compuestos antitombroticos, su preparacion y su utilizacion como medicamentos.
SI2573068T1 (sl) 2004-03-15 2015-03-31 Janssen Pharmaceutica N.V. Postopek za pripravo intermediatov spojin, ki so uporabne kot modulatorji opioidnega receptorja

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7305936A (fr) * 1972-05-05 1973-11-07

Also Published As

Publication number Publication date
FR2407915B1 (fr) 1980-12-26
GB2007663A (en) 1979-05-23
SE7811454L (sv) 1979-05-08
DE2845941A1 (de) 1979-05-10
JPS54106448A (en) 1979-08-21
FR2407915A1 (fr) 1979-06-01

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