DD128659A5 - Verfahren zur herstellung von 4-androsten-3-onen - Google Patents
Verfahren zur herstellung von 4-androsten-3-onenInfo
- Publication number
- DD128659A5 DD128659A5 DD7700197658A DD19765877A DD128659A5 DD 128659 A5 DD128659 A5 DD 128659A5 DD 7700197658 A DD7700197658 A DD 7700197658A DD 19765877 A DD19765877 A DD 19765877A DD 128659 A5 DD128659 A5 DD 128659A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- onen
- androst
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused
- C07J53/004—3 membered carbocyclic rings
- C07J53/007—3 membered carbocyclic rings in position 6-7
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19762609695 DE2609695A1 (de) | 1976-03-05 | 1976-03-05 | 7-substituierte 4-androsten-3-one und verfahren zu ihrer herstellung |
DE19762609694 DE2609694C3 (de) | 1976-03-05 | 1976-03-05 | 17 a-(3-Hydroxpropyl)-17 ß- hydroxy-7 a-thioalkanoyl-4-androsten- 3-one und Verfahren zu deren Herstellung |
DE19762627186 DE2627186A1 (de) | 1976-03-05 | 1976-06-16 | 7-substituierte 4-androsten-3-one und verfahren zu ihrer herstellung iii |
DE19762627187 DE2627187A1 (de) | 1976-06-16 | 1976-06-16 | 7-substituierte 4-androsten-3-one und verfahren zu ihrer herstellung ii |
DE19762644427 DE2644427A1 (de) | 1976-09-30 | 1976-09-30 | 17 beta-hydroxy-17 alpha-(3-acyloxypropyl)-4.6-androstadien-3-one und deren salze |
DE19762646043 DE2646043C2 (de) | 1976-10-08 | 1976-10-08 | 7α-Acetylthio-6α-methyl-4-androsten-3-one, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
DD128659A5 true DD128659A5 (de) | 1977-11-30 |
Family
ID=27544260
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DD7700197658A DD128659A5 (de) | 1976-03-05 | 1977-03-03 | Verfahren zur herstellung von 4-androsten-3-onen |
Country Status (15)
Country | Link |
---|---|
US (1) | US4118488A (fr) |
JP (1) | JPS52111552A (fr) |
AT (2) | AT365611B (fr) |
BE (1) | BE852089A (fr) |
CA (1) | CA1078826A (fr) |
CH (1) | CH631462A5 (fr) |
DD (1) | DD128659A5 (fr) |
DK (1) | DK146856C (fr) |
FR (1) | FR2342990A1 (fr) |
GB (1) | GB1579298A (fr) |
IE (1) | IE44711B1 (fr) |
IL (1) | IL51586A (fr) |
LU (1) | LU76883A1 (fr) |
NL (1) | NL7702369A (fr) |
SE (1) | SE420732B (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS53116361A (en) * | 1977-03-17 | 1978-10-11 | Mitsubishi Chem Ind Ltd | Preparation of 7 acylthioo44enee33oxosteroid |
ES469510A1 (es) * | 1977-05-16 | 1978-12-01 | Schering Ag | Procedimiento para la preparacion de 17beta hidroxi-4-an- drosten-3-onas. |
DE3111951A1 (de) * | 1981-03-23 | 1982-09-30 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | 7(alpha)-alkoxycarbonyl-15ss-methylen-4-androstene, verfahren zu ihrer herstellung und verwendung als arzneimittel |
DE3130644A1 (de) * | 1981-07-29 | 1983-02-17 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue androstan-derivate, verfahren zu ihrer herstellung und pharmazeutische praeparate, die diese verbindungen enthalten |
DE3461090D1 (en) * | 1983-02-18 | 1986-12-04 | Schering Ag | 11-beta-aryl-estradienes, process for their preparation and pharmaceutical compositions containing them |
US4552871A (en) * | 1983-04-13 | 1985-11-12 | Ciba Geigy Corporation | Steroids of the 20-spiroxane series, processes for the manufacture thereof, pharmaceutical preparations containing such compounds and the use of the latter |
WO1997021720A2 (fr) * | 1995-12-11 | 1997-06-19 | G.D. Searle And Co. | Procedes de preparation de steroides 7.alpha.-carboxylyl9,11-epoxy et intermediaires utiles dans ces procedes et procede general d'epoxydation de liaisons olefiniques doubles |
US6887991B1 (en) * | 1996-12-11 | 2005-05-03 | G. D. Searle & Company | Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein |
CN100369927C (zh) | 1996-12-11 | 2008-02-20 | G·D·瑟尔公司 | 9,11-环氧甾族化合物和其中有用的中间体的制备方法 |
US20030083231A1 (en) * | 1998-11-24 | 2003-05-01 | Ahlem Clarence N. | Blood cell deficiency treatment method |
US7235655B2 (en) * | 2002-03-22 | 2007-06-26 | Pharmacia & Upjohn Company | Processes to prepare eplerenone |
JP2005523306A (ja) * | 2002-03-22 | 2005-08-04 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | エプレレノンの製法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3137690A (en) * | 1963-09-26 | 1964-06-16 | Searle & Co | 17beta-hydroxy-3-oxoandrost-4-en-17alpha-ylpropionaldehyde lactol and delta1, delta6, delta1, 6, 19-nor and 7alpha-acetylthio congeners |
DE1250818B (de) * | 1963-10-01 | 1967-09-28 | G. D. Searle & Co., Chicago, 111. (V. St. A.) | Verfahren zur Herstellung von 3-Oxozl4.Asteroiden |
US3798213A (en) * | 1971-01-25 | 1974-03-19 | Merck & Co Inc | 7 alpha-methyl-20-spiroxane-3-ones and process |
US3753979A (en) * | 1971-12-06 | 1973-08-21 | Merck & Co Inc | Substituted 1,2alpha-methylene-6,7alpha-halomethylene-20-spirox-4-en-3-ones or 3-ols and acyl esters thereof |
DE2251476A1 (de) * | 1972-10-20 | 1974-05-02 | Hoechst Ag | Verfahren zur herstellung von beta(3-keto-7 alpha-thioacyl-17 beta-hydroxy4-androsten-17 alpha -yl)-propionsaeuregamma -lactonen |
CH609357A5 (fr) * | 1973-05-25 | 1979-02-28 | Schering Ag |
-
1977
- 1977-03-02 IE IE451/77A patent/IE44711B1/en unknown
- 1977-03-02 CH CH261377A patent/CH631462A5/de not_active IP Right Cessation
- 1977-03-03 IL IL51586A patent/IL51586A/xx unknown
- 1977-03-03 DD DD7700197658A patent/DD128659A5/xx unknown
- 1977-03-03 US US05/773,982 patent/US4118488A/en not_active Expired - Lifetime
- 1977-03-03 AT AT0141377A patent/AT365611B/de not_active IP Right Cessation
- 1977-03-03 LU LU76883A patent/LU76883A1/xx unknown
- 1977-03-04 JP JP2370377A patent/JPS52111552A/ja active Pending
- 1977-03-04 SE SE7702455A patent/SE420732B/xx unknown
- 1977-03-04 BE BE175469A patent/BE852089A/fr not_active IP Right Cessation
- 1977-03-04 DK DK96177A patent/DK146856C/da not_active IP Right Cessation
- 1977-03-04 CA CA273,185A patent/CA1078826A/fr not_active Expired
- 1977-03-04 NL NL7702369A patent/NL7702369A/xx not_active Application Discontinuation
- 1977-03-07 GB GB9464/77A patent/GB1579298A/en not_active Expired
- 1977-03-07 FR FR7706567A patent/FR2342990A1/fr active Granted
-
1980
- 1980-04-02 AT AT0180980A patent/AT370110B/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
GB1579298A (en) | 1980-11-19 |
DK146856B (da) | 1984-01-23 |
DK146856C (da) | 1984-07-02 |
JPS52111552A (en) | 1977-09-19 |
SE7702455L (sv) | 1977-09-06 |
CA1078826A (fr) | 1980-06-03 |
DK96177A (da) | 1977-09-06 |
AT365611B (de) | 1982-02-10 |
FR2342990B1 (fr) | 1979-03-09 |
BE852089A (fr) | 1977-09-05 |
AT370110B (de) | 1983-03-10 |
IE44711L (en) | 1977-09-05 |
CH631462A5 (de) | 1982-08-13 |
ATA180980A (de) | 1982-07-15 |
ATA141377A (de) | 1981-06-15 |
FR2342990A1 (fr) | 1977-09-30 |
LU76883A1 (fr) | 1977-07-11 |
SE420732B (sv) | 1981-10-26 |
US4118488A (en) | 1978-10-03 |
IE44711B1 (en) | 1982-03-10 |
IL51586A0 (en) | 1977-05-31 |
NL7702369A (nl) | 1977-09-07 |
IL51586A (en) | 1981-10-30 |
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