DD128555A5 - Disubstituierte phenolaether des 3-amino-2-hydroxypropans,verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel - Google Patents

Disubstituierte phenolaether des 3-amino-2-hydroxypropans,verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Info

Publication number
DD128555A5
DD128555A5 DD7600195393A DD19539376A DD128555A5 DD 128555 A5 DD128555 A5 DD 128555A5 DD 7600195393 A DD7600195393 A DD 7600195393A DD 19539376 A DD19539376 A DD 19539376A DD 128555 A5 DD128555 A5 DD 128555A5
Authority
DD
German Democratic Republic
Prior art keywords
hydroxypropano
medicaments
amino
preparation
phenol ethers
Prior art date
Application number
DD7600195393A
Other languages
German (de)
English (en)
Inventor
Rudolf Hiltmann
Arend Heise
Stansilav Kazda
Friedrich Hoffmeister
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DD128555A5 publication Critical patent/DD128555A5/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/34—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/36—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by carbon atoms having at least two bonds to oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DD7600195393A 1975-10-23 1976-10-21 Disubstituierte phenolaether des 3-amino-2-hydroxypropans,verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel DD128555A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752547524 DE2547524A1 (de) 1975-10-23 1975-10-23 Disubstituierte phenolaether des 3-amino-2-hydroxypropans, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
DD128555A5 true DD128555A5 (de) 1977-11-23

Family

ID=5959934

Family Applications (1)

Application Number Title Priority Date Filing Date
DD7600195393A DD128555A5 (de) 1975-10-23 1976-10-21 Disubstituierte phenolaether des 3-amino-2-hydroxypropans,verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Country Status (29)

Country Link
US (1) US4110472A (ru)
JP (1) JPS5935387B2 (ru)
AT (2) AT344682B (ru)
AU (1) AU502167B2 (ru)
BE (1) BE847541A (ru)
BG (2) BG31796A3 (ru)
CA (1) CA1085417A (ru)
CH (2) CH623562A5 (ru)
CS (2) CS191344B2 (ru)
DD (1) DD128555A5 (ru)
DE (1) DE2547524A1 (ru)
DK (1) DK480376A (ru)
ES (1) ES452616A1 (ru)
FI (1) FI67075C (ru)
FR (1) FR2328458A1 (ru)
GB (1) GB1497500A (ru)
GR (1) GR61598B (ru)
HU (1) HU174097B (ru)
IE (1) IE43745B1 (ru)
IL (1) IL50732A (ru)
LU (1) LU76057A1 (ru)
NL (1) NL7611683A (ru)
NO (1) NO143844C (ru)
PL (2) PL110002B1 (ru)
PT (1) PT65737B (ru)
RO (1) RO76883A (ru)
SE (1) SE432926B (ru)
SU (2) SU639443A3 (ru)
ZA (1) ZA766303B (ru)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0333938A1 (en) * 1987-12-01 1989-09-27 ZAMBON GROUP S.p.A. 2-Hydroxy-3-aryloxy-propylamine derivatives having cardiovascular activity

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5541204A (en) * 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
BRPI0810063A2 (pt) * 2007-04-20 2014-10-14 Acucela Inc Composto, composição farmacêutica, e, métodos para modular fluxo de cromóforo em um ciclo retinóide, para tratar uma doença ou distúrbio oftálmico em um indivíduo, para inibir adaptação ao escuro em uma célula fotorreceptora de bastão da retina, para inibir regeneração de rodopsina em uma célula fotoreceptora de bastão da retina, para reduzir isquemia em um olho de um indivíduo, para inibir neovascularização na retina de um olho de um indivíduo, e para inibir degeneração de uma célula da retina em uma retina
FR3030514A1 (fr) * 2014-12-18 2016-06-24 Centre De Coop Int En Rech Agronomique Pour Le Dev (Cirad) Dimeres polyaromatiques
EP3144289A1 (en) * 2015-09-16 2017-03-22 Evonik Technochemie GmbH [(2-ethoxy-5-trans-1-propen-1-yl)-phenoxyl]-terminated compounds
CN110035745B (zh) * 2016-10-05 2022-04-29 匹兹堡大学联邦系统高等教育 小分子ampk活化剂

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3758583A (en) * 1971-01-21 1973-09-11 Syntex Corp 2-(2-hydroxy-3-aminopropyl-1-yloxy)-1,6-dilfuoro-and-1,6-methano-{8 10{9 annulenes and the salts thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0333938A1 (en) * 1987-12-01 1989-09-27 ZAMBON GROUP S.p.A. 2-Hydroxy-3-aryloxy-propylamine derivatives having cardiovascular activity

Also Published As

Publication number Publication date
PL110007B1 (en) 1980-06-30
RO76883A (ro) 1981-08-30
AT345792B (de) 1978-10-10
FR2328458B1 (ru) 1979-03-02
FR2328458A1 (fr) 1977-05-20
CS191344B2 (en) 1979-06-29
AT344682B (de) 1978-08-10
AU1879776A (en) 1978-04-27
GR61598B (en) 1978-12-02
NO763442L (ru) 1977-04-26
FI67075B (fi) 1984-09-28
FI67075C (fi) 1985-01-10
ES452616A1 (es) 1978-01-16
GB1497500A (en) 1978-01-12
SE7611686L (sv) 1977-04-24
ATA606377A (de) 1978-02-15
JPS5251352A (en) 1977-04-25
ATA784476A (de) 1977-12-15
PT65737A (en) 1976-11-01
PL110002B1 (en) 1980-06-30
CS191322B2 (en) 1979-06-29
LU76057A1 (ru) 1977-05-31
HU174097B (hu) 1979-11-28
ZA766303B (en) 1977-09-28
AU502167B2 (en) 1979-07-12
IE43745L (en) 1977-04-23
DE2547524A1 (de) 1977-04-28
SU664559A3 (ru) 1979-05-25
SU639443A3 (ru) 1978-12-25
IL50732A0 (en) 1976-12-31
SE432926B (sv) 1984-04-30
IE43745B1 (en) 1981-05-20
NO143844B (no) 1981-01-12
NL7611683A (nl) 1977-04-26
BE847541A (fr) 1977-04-22
FI763010A (ru) 1977-04-24
JPS5935387B2 (ja) 1984-08-28
PL193206A1 (pl) 1979-03-12
BG27732A3 (en) 1979-12-12
CA1085417A (en) 1980-09-09
BG31796A3 (en) 1982-03-15
DK480376A (da) 1977-04-24
CH623562A5 (ru) 1981-06-15
US4110472A (en) 1978-08-29
IL50732A (en) 1979-12-30
NO143844C (no) 1981-04-22
CH630058A5 (de) 1982-05-28
PT65737B (en) 1978-04-20

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