CY2251B1 - Pharmaceutical compositions containing 9-cis retinoic acid salts and esters thereof - Google Patents

Pharmaceutical compositions containing 9-cis retinoic acid salts and esters thereof

Info

Publication number
CY2251B1
CY2251B1 CY0100043A CY0100043A CY2251B1 CY 2251 B1 CY2251 B1 CY 2251B1 CY 0100043 A CY0100043 A CY 0100043A CY 0100043 A CY0100043 A CY 0100043A CY 2251 B1 CY2251 B1 CY 2251B1
Authority
CY
Cyprus
Prior art keywords
esters
retinoic acid
pharmaceutical compositions
cis retinoic
compositions containing
Prior art date
Application number
CY0100043A
Other languages
English (en)
Inventor
Werner Bollag
Joseph Francis Grippo
Arthur Levin
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CY2251B1 publication Critical patent/CY2251B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
CY0100043A 1992-01-22 2001-12-11 Pharmaceutical compositions containing 9-cis retinoic acid salts and esters thereof CY2251B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US82392892A 1992-01-22 1992-01-22
US82374192A 1992-01-22 1992-01-22
US82378692A 1992-01-22 1992-01-22
US82464792A 1992-01-23 1992-01-23

Publications (1)

Publication Number Publication Date
CY2251B1 true CY2251B1 (en) 2003-07-04

Family

ID=27505866

Family Applications (1)

Application Number Title Priority Date Filing Date
CY0100043A CY2251B1 (en) 1992-01-22 2001-12-11 Pharmaceutical compositions containing 9-cis retinoic acid salts and esters thereof

Country Status (20)

Country Link
EP (1) EP0552624B1 (xx)
JP (1) JP3631259B2 (xx)
CN (2) CN1068200C (xx)
AT (1) ATE194077T1 (xx)
AU (1) AU667864B2 (xx)
CA (1) CA2087251C (xx)
CY (1) CY2251B1 (xx)
CZ (1) CZ282548B6 (xx)
DE (1) DE69328910T2 (xx)
DK (1) DK0552624T3 (xx)
ES (1) ES2148184T3 (xx)
GR (1) GR3034323T3 (xx)
HU (2) HU212734B (xx)
IL (1) IL104450A (xx)
NO (1) NO302274B1 (xx)
NZ (1) NZ245686A (xx)
PH (1) PH31621A (xx)
PT (1) PT552624E (xx)
RU (1) RU2119333C1 (xx)
TW (1) TW226329B (xx)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968989A (en) 1991-12-18 1999-10-19 The Salk Institute For Biological Studies Means for the modulation of processes mediated by retinoid receptors and compounds useful therefor
DE617614T1 (de) 1991-12-18 1995-06-08 Salk Inst For Biological Studi Mitteln zur modulierung von verfahren durch retinoid rezeptoren und dafür nützliche verbindungen.
US7056954B2 (en) 1991-12-18 2006-06-06 The Salk Institute For Biological Studies Means for the modulation of processes mediated by retinoid receptors and compounds useful therefor
US5780676A (en) * 1992-04-22 1998-07-14 Ligand Pharmaceuticals Incorporated Compounds having selective activity for Retinoid X Receptors, and means for modulation of processes mediated by Retinoid X Receptors
US7655699B1 (en) 1992-04-22 2010-02-02 Eisai Inc. Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors
US5962731A (en) * 1992-04-22 1999-10-05 Ligand Pharmaceuticals Incorporated Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors
US5549888A (en) * 1994-01-31 1996-08-27 Procter & Gamble Aqueous topical anti-acne compositions of low pH
US5534261A (en) * 1995-01-17 1996-07-09 University Of Southern California Retinoid-based compositions and method for preventing adhesion formation using the same
US7115728B1 (en) 1995-01-30 2006-10-03 Ligand Pharmaceutical Incorporated Human peroxisome proliferator activated receptor γ
US5821254A (en) * 1995-02-17 1998-10-13 The United States Of America As Represented By The Department Of Health And Human Services Uses of 9-cis-retinoic acids and derivatives thereof alone or in combination with antineoplastic agents in the prevention or treatment of cancer
US5807900A (en) * 1995-03-31 1998-09-15 Hoffmann-La Roche, Inc. Method for identifying compounds having increased activity for the repair of skin photodamage
EP0822811A1 (en) * 1995-04-21 1998-02-11 Ligand Pharmaceuticals, Inc. Inhibition of apoptosis in cells expressing fas-ligand following activation
DE19523079A1 (de) * 1995-06-26 1997-01-02 Basf Ag Ester und Amide der 9(Z)-Retinsäure
AU725998B2 (en) * 1995-09-18 2000-10-26 Eisai R&D Management Co., Ltd. Treating NIDDM with RXR agonists
WO1997010813A1 (en) 1995-09-18 1997-03-27 Ligand Pharmaceuticals Incorporated Ppar gamma antagonists for treating obesity
TW442459B (en) * 1996-04-15 2001-06-23 Hoffmann La Roche Retinoid compounds, pharmaceutical composition comprising same and process for the preparation thereof
FR2765480B1 (fr) 1997-07-07 1999-09-10 Oreal Utilisation pour le revetement des matieres keratiniques d'un materiau polymerique hybride ; compositions cosmetiques ou dermatologiques
AU8588798A (en) 1997-07-25 1999-02-16 Institut Pasteur Human peroxisome proliferator activated receptor gamma (ppargamma) gene re gulatory sequences and uses therefor
AU1707599A (en) * 1998-03-20 1999-10-18 Warner-Lambert Company Retinoid-glitazone combinations
NZ514662A (en) 1999-04-07 2004-01-30 Sankyo Co Amine derivatives
JP5249484B2 (ja) * 2001-12-11 2013-07-31 第一三共株式会社 医薬組成物
WO2003086374A1 (en) * 2002-04-05 2003-10-23 University Of Utah Research Foundation Regulation of a novel colon specific retinol dehydrogenase by apc and cdx2
AU2003270414A1 (en) * 2002-09-06 2004-03-29 Oregon Health And Science University Effect of vitamin a gel on paranasal sinus mucosal regeneration
EP1527774A1 (en) 2003-11-03 2005-05-04 Basilea Pharmaceutica AG New formulation for retinoid-containing soft gelatin capsules
JP4825957B2 (ja) * 2005-03-29 2011-11-30 国立大学法人 鹿児島大学 抗腫瘍剤
RU2546005C2 (ru) 2009-09-15 2015-04-10 Кью Эл Ти ИНК. Фармацевтические составы, содержащие 9-цис-ретиниловые сложные эфиры в липидном наполнителе
AU2011241175A1 (en) * 2010-04-16 2012-11-29 Davos Life Science Pte. Ltd. Synergistic interaction of at least one Vitamin E component and tyrosinase inhibitors for dermatological applications
KR20180043846A (ko) 2010-04-19 2018-04-30 노벨리언 테라퓨틱스 인코포레이티드 내인성 레티노이드 결핍과 연관된 시각 장애의 치료 또는 완화를 위한 치료 요법 및 방법
JP6576636B2 (ja) 2012-03-01 2019-09-18 ノベリオン セラピューティクス インコーポレイテッド 内因性レチノイド欠乏に関連する視覚障害における視覚機能を改善するための治療的計画および方法
JP6182728B2 (ja) * 2012-11-02 2017-08-23 国立大学法人名古屋大学 幹細胞を標的とした薬効及び毒性の評価法
EP4215178A1 (en) 2020-09-11 2023-07-26 Chemyunion Ltda Composition, use of the composition, cosmetic method and method for modulating the production of sebum
WO2023168608A1 (en) * 2022-03-08 2023-09-14 Mastery Biotech Co., Ltd. Pharmaceutical composition including retinoic acid and carbohydrate and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA713539B (en) * 1970-06-23 1972-02-23 Hoffmann La Roche Pharmaceutical compositions
AU610587B2 (en) * 1987-04-06 1991-05-23 Daltex Medical Sciences, Inc. Treatment of aged skin with oral 13-cis-retinoic acid
US4994491A (en) * 1988-12-14 1991-02-19 Molecular Design International Dermal uses of trans-retinoids for the treatment of cancer
LU86969A1 (fr) * 1987-08-12 1989-03-08 Oreal Association de derives de pyrimidine et de retinoides en composants separes pour induire et stimuler la croissance des cheveux et diminuer leur chute
DE617614T1 (de) * 1991-12-18 1995-06-08 Salk Inst For Biological Studi Mitteln zur modulierung von verfahren durch retinoid rezeptoren und dafür nützliche verbindungen.

Also Published As

Publication number Publication date
PH31621A (en) 1999-01-12
RU2119333C1 (ru) 1998-09-27
AU3186193A (en) 1993-07-29
CN1068200C (zh) 2001-07-11
PT552624E (pt) 2000-10-31
ATE194077T1 (de) 2000-07-15
JP3631259B2 (ja) 2005-03-23
CZ282548B6 (cs) 1997-08-13
ES2148184T3 (es) 2000-10-16
CZ372892A3 (en) 1993-12-15
IL104450A (en) 1997-03-18
NO930206L (no) 1993-07-23
DE69328910D1 (de) 2000-08-03
CA2087251C (en) 2003-06-24
AU667864B2 (en) 1996-04-18
EP0552624A1 (en) 1993-07-28
HU212734B (en) 1996-10-28
HUT63053A (en) 1993-07-28
CN1074826A (zh) 1993-08-04
EP0552624B1 (en) 2000-06-28
DK0552624T3 (da) 2000-09-25
JPH06107542A (ja) 1994-04-19
NZ245686A (en) 1995-05-26
IL104450A0 (en) 1993-05-13
CA2087251A1 (en) 1993-07-23
GR3034323T3 (en) 2000-12-29
CN1256916A (zh) 2000-06-21
CN1155376C (zh) 2004-06-30
HU211167A9 (en) 1995-11-28
HU9300116D0 (en) 1993-04-28
DE69328910T2 (de) 2001-01-11
NO930206D0 (no) 1993-01-21
NO302274B1 (no) 1998-02-16
TW226329B (xx) 1994-07-11

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