CY2146B1 - Opthalmic compositions comprising combinations of a carbonic anhydrase inhibitor and a beta-adrenergic antagonist - Google Patents

Opthalmic compositions comprising combinations of a carbonic anhydrase inhibitor and a beta-adrenergic antagonist

Info

Publication number
CY2146B1
CY2146B1 CY9900045A CY9900045A CY2146B1 CY 2146 B1 CY2146 B1 CY 2146B1 CY 9900045 A CY9900045 A CY 9900045A CY 9900045 A CY9900045 A CY 9900045A CY 2146 B1 CY2146 B1 CY 2146B1
Authority
CY
Cyprus
Prior art keywords
beta
combinations
carbonic anhydrase
anhydrase inhibitor
adrenergic antagonist
Prior art date
Application number
CY9900045A
Other languages
English (en)
Inventor
John J Bladwin
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27103852&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY2146(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CY2146B1 publication Critical patent/CY2146B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CY9900045A 1991-04-17 1999-12-29 Opthalmic compositions comprising combinations of a carbonic anhydrase inhibitor and a beta-adrenergic antagonist CY2146B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68671891A 1991-04-17 1991-04-17
US83491392A 1992-02-13 1992-02-13

Publications (1)

Publication Number Publication Date
CY2146B1 true CY2146B1 (en) 2002-06-21

Family

ID=27103852

Family Applications (1)

Application Number Title Priority Date Filing Date
CY9900045A CY2146B1 (en) 1991-04-17 1999-12-29 Opthalmic compositions comprising combinations of a carbonic anhydrase inhibitor and a beta-adrenergic antagonist

Country Status (25)

Country Link
EP (1) EP0509752B1 (ja)
JP (1) JP2527513B2 (ja)
KR (1) KR920019348A (ja)
CN (1) CN1073421C (ja)
AT (1) ATE182787T1 (ja)
AU (1) AU648659C (ja)
CA (1) CA2065965C (ja)
CH (1) CH0509752H1 (ja)
CY (1) CY2146B1 (ja)
CZ (1) CZ285129B6 (ja)
DE (3) DE10075002I2 (ja)
DK (1) DK0509752T3 (ja)
ES (1) ES2133304T3 (ja)
GR (1) GR3031467T3 (ja)
HK (1) HK1009251A1 (ja)
IE (1) IE921240A1 (ja)
IL (1) IL101537A (ja)
LU (1) LU90506I2 (ja)
MX (1) MX9201785A (ja)
NL (1) NL990041I2 (ja)
NO (1) NO306196B1 (ja)
RO (1) RO113612B1 (ja)
SK (1) SK282039B6 (ja)
WO (1) WO1992018124A1 (ja)
YU (1) YU39392A (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5932572A (en) * 1992-02-21 1999-08-03 Alcon Laboratories, Inc. Topical anti-glaucoma compositions
AU677577B2 (en) * 1992-02-21 1997-05-01 Alcon Laboratories, Inc. Topical antiglaucoma compositions comprising carbonic anhydrase inhibitors and beta-blockers
US6071904A (en) * 1996-12-11 2000-06-06 Alcon Laboratories, Inc. Process for manufacturing ophthalmic suspensions
FI981473A (fi) * 1998-06-25 1999-12-26 Orion Yhtymae Oyj Menetelmä pulmonaalihypertension hoitamiseksi
TWI298257B (en) 2001-05-31 2008-07-01 Allergan Inc Hypotensive lipid and timolol compositions and methods of using same
CN100345594C (zh) * 2004-01-19 2007-10-31 无锡杰西医药科技有限公司 乙酰唑胺滴眼液
US8211450B2 (en) * 2010-05-05 2012-07-03 Senju Usa, Inc. Ophthalmic composition
PT2598118T (pt) 2010-07-29 2018-11-29 Allergan Inc Soluções de bimatoprost e timolol isentas de conservantes
US9061034B2 (en) 2010-07-29 2015-06-23 Allergan, Inc. Preservative free bimatoprost and timolol solutions
JP5893204B1 (ja) * 2015-02-23 2016-03-23 参天製薬株式会社 防腐効果のある医薬の組合せ
TW201726127A (zh) * 2016-01-29 2017-08-01 參天製藥股份有限公司 含有多佐胺、高分子及硼酸之醫藥組成物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4863922A (en) * 1984-12-12 1989-09-05 Merck & Co., Inc. Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use

Also Published As

Publication number Publication date
DE69229688T4 (de) 2010-08-19
NL990041I1 (nl) 2000-02-01
CN1066781A (zh) 1992-12-09
DK0509752T3 (da) 1999-12-06
ATE182787T1 (de) 1999-08-15
WO1992018124A1 (en) 1992-10-29
NO306196B1 (no) 1999-10-04
LU90506I2 (fr) 2000-03-28
SK282039B6 (sk) 2001-10-08
EP0509752A2 (en) 1992-10-21
KR920019348A (ko) 1992-11-19
IL101537A0 (en) 1992-12-30
NO933714D0 (no) 1993-10-15
YU39392A (sh) 1995-12-04
CN1073421C (zh) 2001-10-24
MX9201785A (es) 1992-10-01
HK1009251A1 (en) 1999-05-28
CZ209893A3 (en) 1994-06-15
AU648659B2 (en) 1994-04-28
GR3031467T3 (en) 2000-01-31
DE10075002I1 (de) 2000-03-30
IL101537A (en) 1997-11-20
CZ285129B6 (cs) 1999-05-12
IE921240A1 (en) 1992-10-21
NL990041I2 (nl) 2000-04-03
DE10075002I2 (de) 2004-07-01
ES2133304T3 (es) 1999-09-16
NO933714L (no) 1993-10-15
EP0509752A3 (en) 1993-03-03
EP0509752B1 (en) 1999-08-04
CA2065965A1 (en) 1992-10-18
AU648659C (en) 2008-02-14
DE69229688D1 (de) 1999-09-09
AU1497992A (en) 1992-10-22
CH0509752H1 (ja) 2012-11-30
DE69229688T2 (de) 2000-02-24
RO113612B1 (ro) 1998-09-30
DE69229688C5 (de) 2010-10-21
SK110393A3 (en) 1994-02-02
JP2527513B2 (ja) 1996-08-28
JPH05117167A (ja) 1993-05-14
CA2065965C (en) 1998-06-16

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