CY1126101T1 - Αναστολεις sglt2 για τη θεραπεια μεταβολικων διαταραχων σε κυνοειδη - Google Patents
Αναστολεις sglt2 για τη θεραπεια μεταβολικων διαταραχων σε κυνοειδηInfo
- Publication number
- CY1126101T1 CY1126101T1 CY20231100353T CY231100353T CY1126101T1 CY 1126101 T1 CY1126101 T1 CY 1126101T1 CY 20231100353 T CY20231100353 T CY 20231100353T CY 231100353 T CY231100353 T CY 231100353T CY 1126101 T1 CY1126101 T1 CY 1126101T1
- Authority
- CY
- Cyprus
- Prior art keywords
- metabolic disorder
- hyperglycemia
- inflammation
- treatment
- sglt2 inhibitors
- Prior art date
Links
- 208000030159 metabolic disease Diseases 0.000 title abstract 5
- 229940123518 Sodium/glucose cotransporter 2 inhibitor Drugs 0.000 title abstract 2
- 206010061218 Inflammation Diseases 0.000 abstract 4
- 230000004054 inflammatory process Effects 0.000 abstract 4
- 201000001421 hyperglycemia Diseases 0.000 abstract 3
- 208000002177 Cataract Diseases 0.000 abstract 2
- 206010020772 Hypertension Diseases 0.000 abstract 2
- 206010022489 Insulin Resistance Diseases 0.000 abstract 2
- 208000023178 Musculoskeletal disease Diseases 0.000 abstract 2
- 201000009104 prediabetes syndrome Diseases 0.000 abstract 2
- 230000008085 renal dysfunction Effects 0.000 abstract 2
- 230000009885 systemic effect Effects 0.000 abstract 2
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 2
- 241000282465 Canis Species 0.000 abstract 1
- 208000032928 Dyslipidaemia Diseases 0.000 abstract 1
- 208000002705 Glucose Intolerance Diseases 0.000 abstract 1
- 206010018429 Glucose tolerance impaired Diseases 0.000 abstract 1
- 206010060378 Hyperinsulinaemia Diseases 0.000 abstract 1
- 206010023379 Ketoacidosis Diseases 0.000 abstract 1
- 208000007976 Ketosis Diseases 0.000 abstract 1
- 208000017170 Lipid metabolism disease Diseases 0.000 abstract 1
- 208000001145 Metabolic Syndrome Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 208000001280 Prediabetic State Diseases 0.000 abstract 1
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 abstract 1
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 208000010706 fatty liver disease Diseases 0.000 abstract 1
- 230000003451 hyperinsulinaemic effect Effects 0.000 abstract 1
- 201000008980 hyperinsulinism Diseases 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 210000000496 pancreas Anatomy 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
- 208000035408 type 1 diabetes mellitus 1 Diseases 0.000 abstract 1
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- Neurology (AREA)
Abstract
Η παρούσα εφεύρεση σχετίζεται με έναν ή περισσότερους αναστολείς SGLT2 ή φαρμακευτικά αποδεκτές μορφές τους για χρήση στη θεραπεία ή/και την πρόληψη μιας μεταβολικής διαταραχής σε ένα κυνοειδές, κατά προτίμηση όπου η μεταβολική διαταραχή είναι μια ή περισσότερες που επιλέγονται από την ομάδα που αποτελείται από: κετοξέωση, προδιαβήτη, ινσουλινοεξαρτώμενο σακχαρώδη διαβήτη, διαβήτη αντίστασης στην ινσουλίνη, αντίσταση στην ινσουλίνη, παχυσαρκία, υπεργλυκαιμία, σχηματισμό καταρράκτη που προκαλείται από υπεργλυκαιμία, μειωμένη ανοχή στη γλυκόζη, υπερινσουλιναιμία, δυσλιπιδαιμία, δυσαδιποκιναιμία, υποκλινική φλεγμονή, συστηματική φλεγμονή, συστηματική φλεγμονή χαμηλού βαθμού, ηπατική λιπίδωση, φλεγμονή του παγκρέατος, συνέπειες μεταβολικής διαταραχής, όπως υπέρταση, νεφρική δυσλειτουργία ή/και μυοσκελετικές διαταραχές, ή/και Σύνδρομο Χ (μεταβολικό σύνδρομο], όπου κατά προτίμηση αποτρέπεται η ανάπτυξη σχηματισμού καταρράκτη που προκαλείται από υπεργλυκαιμία ή επιτυγχάνεται ύφεση ή/και όπου κατά προτίμηση η ανάπτυξη των συνεπειών της μεταβολικής διαταραχής, όπως υπέρταση, νεφρική δυσλειτουργία ή/και μυοσκελετικές διαταραχές, αποτρέπεται ή επιβραδύνεται η εξέλιξη ή επιτυγχάνεται ύφεση.
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EP14155327 | 2014-01-23 | ||
EP14152327 | 2014-01-23 | ||
EP14186477 | 2014-09-25 | ||
EP15701502.5A EP3096765B1 (en) | 2014-01-23 | 2015-01-20 | Treatment of metabolic disorders in canine animals |
PCT/EP2015/050940 WO2015110402A1 (en) | 2014-01-23 | 2015-01-20 | Treatment of metabolic disorders in canine animals |
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CY20231100353T CY1126101T1 (el) | 2014-01-23 | 2023-07-21 | Αναστολεις sglt2 για τη θεραπεια μεταβολικων διαταραχων σε κυνοειδη |
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JP (3) | JP6239775B2 (el) |
KR (3) | KR20220097538A (el) |
CN (3) | CN105960242A (el) |
AU (2) | AU2015208291B2 (el) |
CA (2) | CA2932674C (el) |
CY (1) | CY1126101T1 (el) |
DK (2) | DK3096765T3 (el) |
EA (2) | EA201891406A1 (el) |
ES (2) | ES2712860T3 (el) |
FI (1) | FI3485890T3 (el) |
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LT (1) | LT3485890T (el) |
MX (2) | MX2016009421A (el) |
PL (2) | PL3096765T3 (el) |
RS (1) | RS64355B1 (el) |
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PT2981269T (pt) | 2013-04-04 | 2023-10-10 | Boehringer Ingelheim Vetmedica Gmbh | Tratamento de distúrbios metabólicos em animais equinos |
TR201901110T4 (tr) * | 2013-04-05 | 2019-02-21 | Boehringer Ingelheim Int | Empagliflozinin terapötik kullanımları. |
FI3862003T3 (fi) | 2013-12-17 | 2023-12-28 | Boehringer Ingelheim Vetmedica Gmbh | SGLT-2-ihibiittori käytettäväksi aineenvaihdutahäiriön hoidossa kissaeläimillä |
KR20220097538A (ko) | 2014-01-23 | 2022-07-07 | 베링거잉겔하임베트메디카게엠베하 | 개과 동물에서 대사 장애의 치료 |
MX2016012705A (es) | 2014-04-01 | 2016-12-16 | Boehringer Ingelheim Vetmedica Gmbh | Tratamiento de trastornos metabolicos en animales equinos. |
NZ728804A (en) | 2014-09-25 | 2022-10-28 | Boehringer Ingelheim Vetmedica Gmbh | Combination treatment of sglt2 inhibitors and dopamine agonists for preventing metabolic disorders in equine animals |
JP6682621B2 (ja) | 2015-08-27 | 2020-04-15 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーBoehringer Ingelheim Vetmedica GmbH | Sglt−2阻害剤含む液体医薬組成物 |
CN111826352A (zh) * | 2019-04-22 | 2020-10-27 | 苏州方德门达新药开发有限公司 | 通用型car-t细胞、其制备及应用 |
US20230381101A1 (en) * | 2022-05-25 | 2023-11-30 | Boehringer Ingelheim Vetmedica Gmbh | Aqueous pharmaceutical compositions comprising sglt-2 inhibitors |
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