CY1124945T1 - Συνθεση περιεχουσα εκχυλισμα του φλοιου του poria cocos για προληψη, βελτιωση ή αγωγη νευροεκφυλιστικων διαταραχων - Google Patents
Συνθεση περιεχουσα εκχυλισμα του φλοιου του poria cocos για προληψη, βελτιωση ή αγωγη νευροεκφυλιστικων διαταραχωνInfo
- Publication number
- CY1124945T1 CY1124945T1 CY20211100941T CY211100941T CY1124945T1 CY 1124945 T1 CY1124945 T1 CY 1124945T1 CY 20211100941 T CY20211100941 T CY 20211100941T CY 211100941 T CY211100941 T CY 211100941T CY 1124945 T1 CY1124945 T1 CY 1124945T1
- Authority
- CY
- Cyprus
- Prior art keywords
- prevention
- treatment
- poria cocos
- neurodegenerative disorders
- improvement
- Prior art date
Links
- 230000002265 prevention Effects 0.000 title abstract 4
- 235000008599 Poria cocos Nutrition 0.000 title abstract 3
- 241001619444 Wolfiporia cocos Species 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 208000015122 neurodegenerative disease Diseases 0.000 title abstract 2
- 208000012902 Nervous system disease Diseases 0.000 abstract 2
- 208000025966 Neurological disease Diseases 0.000 abstract 2
- 230000003412 degenerative effect Effects 0.000 abstract 2
- 230000005764 inhibitory process Effects 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 102000012440 Acetylcholinesterase Human genes 0.000 abstract 1
- 108010022752 Acetylcholinesterase Proteins 0.000 abstract 1
- 102000013455 Amyloid beta-Peptides Human genes 0.000 abstract 1
- 108010090849 Amyloid beta-Peptides Proteins 0.000 abstract 1
- 229940022698 acetylcholinesterase Drugs 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000003941 amyloidogenesis Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 235000013402 health food Nutrition 0.000 abstract 1
- 230000006883 memory enhancing effect Effects 0.000 abstract 1
- 230000014537 nerve growth factor production Effects 0.000 abstract 1
- 210000002569 neuron Anatomy 0.000 abstract 1
- 230000000324 neuroprotective effect Effects 0.000 abstract 1
- 230000026731 phosphorylation Effects 0.000 abstract 1
- 238000006366 phosphorylation reaction Methods 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Non-Alcoholic Beverages (AREA)
Abstract
Η παρούσα εφεύρεση σχετίζεται με φαρμακευτική σύνθεση και με σύνθεση τροφίμου για πρόληψη ή βελτίωση εκφυλιστικής νευρολογικής πάθησης περιλαμβάνουσες εκχύλισμα του φλοιού του Poria cocos για πρόληψη, ή αγωγή νευροεκφυλιστικών διαταραχών. Το εκχύλισμα του φλοιού του Poria cocos, το οποίο είναι το δραστικό συστατικό που περιέχεται στη σύνθεση της παρούσας εφεύρεσης, έχει δραστικότητα βελτίωσης μνήμης μέσω αναστολής της εστεράσης ακετυλοχολίνης και ασκεί νευροπροστατευτική επίδραση και προστασία νευρώνων μέσω αναστολής του σχηματισμού του β αμυλοειδούς και της tau φωσφορυλίωσης και προαγωγής της NGF παραγωγής. Έτσι, η παρούσα εφεύρεση αναμένεται να είναι χρήσιμη ως φαρμακευτική σύνθεση για την πρόληψη ή αγωγή εκφυλιστικών νευρολογικών παθήσεων, ή ως υγιεινό τρόφιμο για τον παραπάνω σκοπό.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020140184853A KR101698163B1 (ko) | 2014-12-19 | 2014-12-19 | 복령피 추출물을 함유하는 퇴행성 신경질환의 예방, 개선 또는 치료용 조성물 |
| PCT/KR2015/013136 WO2016099056A2 (ko) | 2014-12-19 | 2015-12-03 | 복령피 추출물을 함유하는 퇴행성 신경질환의 예방, 개선 또는 치료용 조성물 |
| EP15870223.3A EP3235502B1 (en) | 2014-12-19 | 2015-12-03 | Composition containing poria cocos bark extract for preventing, improving or treating neurodegenerative disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1124945T1 true CY1124945T1 (el) | 2023-01-05 |
Family
ID=56127796
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20201100474T CY1123293T1 (el) | 2014-12-19 | 2020-05-25 | Συνθεση που περιεχει εκχυλισμα του φλοιου poria cocos για την προληψη, τη βελτιωση ή τη θεραπευτικη αντιμετωπιση των νευροεκφυλιστικων διαταραχων |
| CY20211100941T CY1124945T1 (el) | 2014-12-19 | 2021-11-02 | Συνθεση περιεχουσα εκχυλισμα του φλοιου του poria cocos για προληψη, βελτιωση ή αγωγη νευροεκφυλιστικων διαταραχων |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20201100474T CY1123293T1 (el) | 2014-12-19 | 2020-05-25 | Συνθεση που περιεχει εκχυλισμα του φλοιου poria cocos για την προληψη, τη βελτιωση ή τη θεραπευτικη αντιμετωπιση των νευροεκφυλιστικων διαταραχων |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10864238B2 (el) |
| EP (2) | EP3632454B1 (el) |
| JP (1) | JP6533294B2 (el) |
| KR (1) | KR101698163B1 (el) |
| CN (2) | CN113712998A (el) |
| BR (1) | BR112017012909B1 (el) |
| CY (2) | CY1123293T1 (el) |
| DK (2) | DK3632454T3 (el) |
| HU (2) | HUE056404T2 (el) |
| RU (1) | RU2678982C2 (el) |
| SI (2) | SI3632454T1 (el) |
| WO (1) | WO2016099056A2 (el) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6844829B2 (ja) * | 2016-07-21 | 2021-03-17 | 日本メナード化粧品株式会社 | 幹細胞の未分化状態維持剤及び増殖促進剤 |
| KR102295786B1 (ko) * | 2016-09-06 | 2021-09-01 | 신파 티엔리 파머슈티컬 컴퍼니 리미티드 (항저우) | 스킨케어 및/또는 상처치유 촉진에 있어서 복령 추출물 및 이의 활성 성분의 용도 |
| CN111759915A (zh) * | 2020-07-20 | 2020-10-13 | 南通大学 | 一种神经再生复方制剂及其制备方法和用途 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ192673A (en) * | 1979-02-02 | 1984-07-06 | Merck & Co Inc | Ophthalmic compositions for lowering intraocular pressure |
| AU1672397A (en) * | 1996-02-15 | 1997-09-02 | Daiichi Pharmaceutical Co., Ltd. | Brain activators |
| KR100615389B1 (ko) * | 2002-08-23 | 2006-08-25 | (주)헬릭서 | 다래 추출물을 함유하는 알러지성 질환 및 비알러지성염증 질환의 예방 및 개선용 건강 기능 식품 |
| KR100526628B1 (ko) | 2003-03-21 | 2005-11-08 | 주식회사 에스티씨나라 | 모노아민산화효소 저해활성을 갖는 상심자 추출물을함유한 조성물 |
| KR20050092292A (ko) * | 2004-03-15 | 2005-09-21 | 주식회사 크라우젠 | 기억력 증강 효과가 있는 생약재 조성물 |
| KR100779179B1 (ko) * | 2006-05-19 | 2007-11-28 | 충북대학교 산학협력단 | 토복령의 메탄올 추출물을 함유하는 뇌신경 보호 또는퇴행성뇌질환 예방 또는 치료제 |
| KR100847343B1 (ko) * | 2006-12-08 | 2008-07-21 | 경희대학교 산학협력단 | 생약복합재 추출물을 함유하는 골길이 성장 촉진용 조성물 |
| CN101152554A (zh) | 2007-09-24 | 2008-04-02 | 徐大洋 | 治疗荨麻疹既泄热消疹的中药 |
| KR20090071704A (ko) * | 2007-12-28 | 2009-07-02 | 퓨리메드 주식회사 | 치매 예방 및 치료용 조성물 |
| KR101072662B1 (ko) * | 2008-12-18 | 2011-10-11 | 대구한의대학교산학협력단 | 복신 건조분말 또는 그 추출물을 유효성분으로 함유하는건망증 및 기억력 장애 관련 질환의 예방 및 치료용 조성물 |
| KR101064258B1 (ko) | 2008-12-29 | 2011-09-14 | 한국과학기술연구원 | 벤조아릴우레이도 화합물, 및 이를 함유하는 퇴행성 뇌질환예방 또는 치료용 조성물 |
| KR20100083632A (ko) * | 2009-01-14 | 2010-07-22 | 울산대학교 산학협력단 | 표적 단백질 분해효소 감응형 항암제 전구체 |
| KR20110119983A (ko) | 2010-04-28 | 2011-11-03 | 순천대학교 산학협력단 | 뽕나무 열매 추출물을 함유하는 아세틸콜린에스테라제 억제용 조성물 |
| CN102133351B (zh) | 2011-03-04 | 2012-05-09 | 费萍 | 一种治疗阿尔茨海默病的药物组合物及其制备方法 |
| CN102133242B (zh) * | 2011-03-07 | 2013-12-11 | 北京中医药大学 | 一种茯苓提取物及其制备方法 |
| JP6108452B2 (ja) | 2012-04-12 | 2017-04-05 | クラシエ製薬株式会社 | 細胞死抑制組成物 |
| KR101251866B1 (ko) | 2012-07-12 | 2013-04-10 | 순천대학교 산학협력단 | 뽕나무 열매 추출물을 함유하는 아세틸콜린에스테라제 억제용 조성물 |
| EP2929888B1 (en) * | 2012-12-06 | 2018-10-10 | Korea Food Research Institute | Composition comprising poria cocos wolf bark extract as active ingredient for use in preventing, improving, or treating th2-mediated allergic diseases |
| KR101577392B1 (ko) * | 2012-12-06 | 2015-12-17 | 한국식품연구원 | 복령피 추출물을 유효성분으로 포함하는 Ｔｈ1-매개 면역 질환 또는 Ｔｈ2-매개 면역 질환의 예방, 개선 또는 치료용 조성물 |
| CN103393809B (zh) * | 2013-07-24 | 2015-01-07 | 张立东 | 治疗帕金森的药物 |
| CN104013891A (zh) | 2014-05-28 | 2014-09-03 | 高益槐 | 一种益智健脑的复方制剂及其制备方法 |
| KR101671437B1 (ko) | 2014-12-19 | 2016-11-01 | 동아에스티 주식회사 | 상심자 및 복령피 혼합 추출물을 함유하는 퇴행성 신경질환의 예방, 개선 또는 치료용 조성물 |
-
2014
- 2014-12-19 KR KR1020140184853A patent/KR101698163B1/ko active IP Right Grant
-
2015
- 2015-12-03 SI SI201531724T patent/SI3632454T1/sl unknown
- 2015-12-03 RU RU2017123243A patent/RU2678982C2/ru active
- 2015-12-03 SI SI201531202T patent/SI3235502T1/sl unknown
- 2015-12-03 DK DK19210811.6T patent/DK3632454T3/da active
- 2015-12-03 JP JP2017532138A patent/JP6533294B2/ja active Active
- 2015-12-03 BR BR112017012909-4A patent/BR112017012909B1/pt active IP Right Grant
- 2015-12-03 EP EP19210811.6A patent/EP3632454B1/en active Active
- 2015-12-03 EP EP15870223.3A patent/EP3235502B1/en active Active
- 2015-12-03 WO PCT/KR2015/013136 patent/WO2016099056A2/ko active Application Filing
- 2015-12-03 CN CN202111105525.8A patent/CN113712998A/zh active Pending
- 2015-12-03 HU HUE19210811A patent/HUE056404T2/hu unknown
- 2015-12-03 CN CN201580069243.3A patent/CN107106620A/zh active Pending
- 2015-12-03 HU HUE15870223A patent/HUE049254T2/hu unknown
- 2015-12-03 US US15/535,478 patent/US10864238B2/en active Active
- 2015-12-03 DK DK15870223.3T patent/DK3235502T3/da active
-
2020
- 2020-05-25 CY CY20201100474T patent/CY1123293T1/el unknown
- 2020-11-13 US US17/097,592 patent/US20210128656A1/en not_active Abandoned
-
2021
- 2021-11-02 CY CY20211100941T patent/CY1124945T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3235502A2 (en) | 2017-10-25 |
| RU2678982C2 (ru) | 2019-02-05 |
| EP3632454A1 (en) | 2020-04-08 |
| WO2016099056A3 (ko) | 2016-08-11 |
| WO2016099056A2 (ko) | 2016-06-23 |
| JP6533294B2 (ja) | 2019-06-19 |
| CY1123293T1 (el) | 2021-12-31 |
| SI3235502T1 (sl) | 2020-07-31 |
| KR101698163B1 (ko) | 2017-01-19 |
| JP2018500331A (ja) | 2018-01-11 |
| BR112017012909B1 (pt) | 2021-06-15 |
| US20170368122A1 (en) | 2017-12-28 |
| RU2017123243A (ru) | 2019-01-21 |
| EP3235502A4 (en) | 2018-07-18 |
| RU2017123243A3 (el) | 2019-01-21 |
| CN107106620A (zh) | 2017-08-29 |
| HUE056404T2 (hu) | 2022-02-28 |
| US20210128656A1 (en) | 2021-05-06 |
| EP3235502B1 (en) | 2020-02-26 |
| WO2016099056A8 (ko) | 2017-06-29 |
| SI3632454T1 (sl) | 2021-11-30 |
| CN113712998A (zh) | 2021-11-30 |
| HUE049254T2 (hu) | 2020-09-28 |
| KR20160075183A (ko) | 2016-06-29 |
| DK3632454T3 (da) | 2021-11-08 |
| EP3632454B1 (en) | 2021-08-11 |
| BR112017012909A2 (pt) | 2018-01-09 |
| US10864238B2 (en) | 2020-12-15 |
| DK3235502T3 (da) | 2020-06-02 |
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