CY1124899T1 - Μια συνεργιστικη συνθεση ως ενας προωθητης αυτοφαγιας - Google Patents

Μια συνεργιστικη συνθεση ως ενας προωθητης αυτοφαγιας

Info

Publication number
CY1124899T1
CY1124899T1 CY20221100021T CY221100021T CY1124899T1 CY 1124899 T1 CY1124899 T1 CY 1124899T1 CY 20221100021 T CY20221100021 T CY 20221100021T CY 221100021 T CY221100021 T CY 221100021T CY 1124899 T1 CY1124899 T1 CY 1124899T1
Authority
CY
Cyprus
Prior art keywords
autophagy
hair
promoting
synergic composition
promoter
Prior art date
Application number
CY20221100021T
Other languages
English (en)
Inventor
Ralf Paus
Benedetto GRIMALDI
Barbara MARZANI
Sergio Baroni
Giammaria Giuliani
Original Assignee
Giuliani S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Giuliani S.P.A. filed Critical Giuliani S.P.A.
Publication of CY1124899T1 publication Critical patent/CY1124899T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25—Silicon; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/132—Amines having two or more amino groups, e.g. spermidine, putrescine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/673—Vitamin B group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

Η εφεύρεση σχετίζεται με μια συνεργιστική σύνθεση, η οποία περιλαμβάνει ένα ξηρό εκχύλισμα φυτού του γένους Galeopsis και μια ένωση που προάγει την αυτοφαγία που επιλέγεται από βιοτίνη και R-N1-σπερμιδίνη ή ένα άλας αυτών, όπου το R είναι υδρογόνο ή μεθύλιο και μείγματα αυτών. Οι συνεργιστικές συνθέσεις σύμφωνα με την εφεύρεση μπορεί να έχουν τη μορφή τοπικού σκευάσματος ή από του στόματος σκευάσματος και είναι χρήσιμες ως προωθητής της αυτοφαγίας ειδικά σε κύτταρα τριχοθυλακίων τριχωτού της κεφαλής ανθρώπου και στην προώθηση της ανάπτυξης των μαλλιών ή/και στη θεραπεία της αραίωσης των μαλλιών ή απώλειας μαλλιών.
CY20221100021T 2017-08-03 2022-01-07 Μια συνεργιστικη συνθεση ως ενας προωθητης αυτοφαγιας CY1124899T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT102017000089680A IT201700089680A1 (it) 2017-08-03 2017-08-03 Composizione sinergica come promoter di autofagia/a synergistic composition as a promoter of autophagy
PCT/EP2018/071005 WO2019025548A1 (en) 2017-08-03 2018-08-02 SYNERGIC COMPOSITION AS A PROMOTER OF AUTOPHAGIA

Publications (1)

Publication Number Publication Date
CY1124899T1 true CY1124899T1 (el) 2023-01-05

Family

ID=60451125

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20221100021T CY1124899T1 (el) 2017-08-03 2022-01-07 Μια συνεργιστικη συνθεση ως ενας προωθητης αυτοφαγιας

Country Status (26)

Country Link
US (1) US11273193B2 (el)
EP (1) EP3661534B1 (el)
JP (1) JP7307715B2 (el)
CN (1) CN111447937B (el)
AU (1) AU2018309342A1 (el)
BR (1) BR112020002216B1 (el)
CA (1) CA3071317A1 (el)
CY (1) CY1124899T1 (el)
DK (1) DK3661534T3 (el)
EA (1) EA202090437A1 (el)
ES (1) ES2902036T3 (el)
HR (1) HRP20212016T1 (el)
HU (1) HUE057354T2 (el)
IL (1) IL272371B (el)
IT (1) IT201700089680A1 (el)
LT (1) LT3661534T (el)
MA (1) MA49755B1 (el)
MD (1) MD3661534T2 (el)
MX (1) MX2020001317A (el)
PL (1) PL3661534T3 (el)
PT (1) PT3661534T (el)
RS (1) RS62766B1 (el)
SA (1) SA520411228B1 (el)
SG (1) SG11202000953VA (el)
SI (1) SI3661534T1 (el)
WO (1) WO2019025548A1 (el)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201700003045A1 (it) * 2017-01-12 2018-07-12 Giuliani Spa Estratto vegetale per prevenire e trattare la caduta dei capelli

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2751878B1 (fr) * 1996-07-30 1998-09-04 Oreal Utilisation dans une composition d'un extrait d'au moins une labiee
TWI282275B (en) * 2000-08-17 2007-06-11 Control Ox Oy Plant-derived and synthetic phenolic compounds and plant extracts, effective in the treatment and prevention of chlamydial infections
ITMI20020189A1 (it) * 2002-02-01 2003-08-01 Giuliani Spa Composizione per uso farmaceutico o dietetico per contrastare la caduta dei capelli
ITMI20050498A1 (it) * 2005-03-24 2006-09-25 Giuliani Spa Composizione a base di estratti vegetali di ajuga reptans per prevenire la caduta dei capelli stimolare la crescita dei capelli regolare la produzione di sebo
FR2916977A1 (fr) * 2007-06-06 2008-12-12 Engelhard Lyon Sa STIMULATION DE LA SYNTHESE DES RECPTEURS MCR1, MCR2 ET µ OPIOIDE.
ITMI20110644A1 (it) * 2011-04-14 2012-10-15 Giuliani Spa Sistema per il rilascio prolungato di agenti cosmetici
WO2013040005A1 (en) * 2011-09-13 2013-03-21 Monsanto Technology Llc Methods and compositions for weed control
AR090316A1 (es) * 2012-03-13 2014-11-05 Marrone Bio Innovations Inc Cepa de flavobacterium plaguicida y composiciones bioactivas, metabolitos y usos
ITMI20121323A1 (it) * 2012-07-27 2014-01-28 Giuliani Spa Composizione farmaceutica o cosmeticaper il trattamento dell' alopecia
AU2014252200A1 (en) * 2013-04-09 2015-10-29 Chris TUTTLE Formulations and methods for control of weedy species
ITMI20130554A1 (it) * 2013-04-09 2014-10-10 Giuliani Spa Composizione farmaceutica o cosmetica atta a preservare le cellule staminali epiteliali
ITMI20131792A1 (it) * 2013-10-28 2015-04-29 Giuliani Spa Uso di un estratto vegetale per la prevenzione e trattamento della caduta dei capelli

Also Published As

Publication number Publication date
EA202090437A1 (ru) 2020-06-08
DK3661534T3 (da) 2021-12-20
AU2018309342A1 (en) 2020-03-19
PT3661534T (pt) 2021-12-30
SI3661534T1 (sl) 2022-04-29
SA520411228B1 (ar) 2023-02-23
HUE057354T2 (hu) 2022-05-28
BR112020002216B1 (pt) 2023-03-21
JP2020529404A (ja) 2020-10-08
JP7307715B2 (ja) 2023-07-12
WO2019025548A1 (en) 2019-02-07
PL3661534T3 (pl) 2022-02-21
BR112020002216A2 (pt) 2020-07-28
IL272371A (en) 2020-03-31
SG11202000953VA (en) 2020-02-27
MX2020001317A (es) 2020-03-20
LT3661534T (lt) 2022-01-10
CN111447937A (zh) 2020-07-24
CN111447937B (zh) 2022-05-24
US20210177925A1 (en) 2021-06-17
HRP20212016T1 (hr) 2022-04-01
EP3661534B1 (en) 2021-10-20
IL272371B (en) 2022-04-01
EP3661534A1 (en) 2020-06-10
MD3661534T2 (ro) 2022-03-31
CA3071317A1 (en) 2019-02-07
RS62766B1 (sr) 2022-01-31
MA49755A (fr) 2020-06-10
MA49755B1 (fr) 2021-12-31
US11273193B2 (en) 2022-03-15
IT201700089680A1 (it) 2019-02-03
ES2902036T3 (es) 2022-03-24

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