CY1124453T1 - Πολυπεπτιδια που περιεχουν επικρατειες προσδεσης de novo και χρησεις αυτων - Google Patents

Πολυπεπτιδια που περιεχουν επικρατειες προσδεσης de novo και χρησεις αυτων

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Publication number
CY1124453T1
CY1124453T1 CY20211100483T CY211100483T CY1124453T1 CY 1124453 T1 CY1124453 T1 CY 1124453T1 CY 20211100483 T CY20211100483 T CY 20211100483T CY 211100483 T CY211100483 T CY 211100483T CY 1124453 T1 CY1124453 T1 CY 1124453T1
Authority
CY
Cyprus
Prior art keywords
dbdpp
collections
polypeptides containing
binding regions
novo binding
Prior art date
Application number
CY20211100483T
Other languages
English (en)
Inventor
David William LAFLEUR
David M. Hilbert
Original Assignee
Subdomain, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Subdomain, Llc filed Critical Subdomain, Llc
Publication of CY1124453T1 publication Critical patent/CY1124453T1/el

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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Abstract

Παρέχονται στο παρόν πολυπεπτίδια που περιέχουν επικράτειες πρόσδεσης de novo (DBDpp) τα οποία προσδένουν συγκεκριμένα έναν στόχο που ενδιαφέρει. Παρέχονται επίσης νουκλεϊνικά οξέα που κωδικοποιούν τα DBDpp, και φορείς και κύτταρα ξενιστές που περιέχουν τα νουκλεϊνικά οξέα. Περιλαμβάνονται επίσης συλλογές DBDpp, μέθοδοι παραγωγής και διαλογής τέτοιων συλλογών και τα DBDpp που ταυτοποιούνται από τέτοιες συλλογές και διαλογές. Επιπλέον, παρέχονται μέθοδοι παρασκευής και χρήσης των DBDpp. Τέτοιες χρήσεις περιλαμβάνουν, χωρίς περιορισμό, καθαρισμό συγγένειας, και διαγνωστικές και θεραπευτικές εφαρμογές.
CY20211100483T 2015-04-06 2021-06-03 Πολυπεπτιδια που περιεχουν επικρατειες προσδεσης de novo και χρησεις αυτων CY1124453T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562143772P 2015-04-06 2015-04-06
PCT/US2016/025868 WO2016164305A1 (en) 2015-04-06 2016-04-04 De novo binding domain containing polypeptides and uses thereof

Publications (1)

Publication Number Publication Date
CY1124453T1 true CY1124453T1 (el) 2022-07-22

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