CY1124021T1 - Anti-orai1 αντισωμα - Google Patents

Anti-orai1 αντισωμα

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Publication number
CY1124021T1
CY1124021T1 CY20211100285T CY211100285T CY1124021T1 CY 1124021 T1 CY1124021 T1 CY 1124021T1 CY 20211100285 T CY20211100285 T CY 20211100285T CY 211100285 T CY211100285 T CY 211100285T CY 1124021 T1 CY1124021 T1 CY 1124021T1
Authority
CY
Cyprus
Prior art keywords
orai1
diseases
antibody
human
orai1 antibody
Prior art date
Application number
CY20211100285T
Other languages
English (en)
Inventor
Tomoaki Komai
Takako Kimura
Daichi BABA
Yoshikuni ONODERA
Kento TANAKA
Takashi Kagari
Anri AKI
Nobumi NAGAOKA
Original Assignee
Daiichi Sankyo Company, Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Company, Limited filed Critical Daiichi Sankyo Company, Limited
Publication of CY1124021T1 publication Critical patent/CY1124021T1/el

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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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Abstract

Προορίζεται να παρέχει θεραπευτικό ή/και προφυλακτικό παράγοντα για απορρίψεις μοσχεύματος, ανοσολογικές ασθένειες, αλλεργικές ασθένειες, φλεγμονώδεις ασθένειες, θρόμβωση, καρκίνους κ.λπ., στοχεύοντας την ανθρώπινη Orai1. Η παρούσα εφεύρεση παρέχει, για παράδειγμα, φαρμακευτική σύνθεση που περιλαμβάνει αντίσωμα το οποίο ειδικώς αναγνωρίζει την ανθρώπινη Orai1 και έχει τη δραστικότητα αναστολής της ενεργοποίησης ανθρώπινων Τ κυττάρων.
CY20211100285T 2014-08-07 2021-04-02 Anti-orai1 αντισωμα CY1124021T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014161449 2014-08-07
PCT/JP2015/072305 WO2016021674A1 (ja) 2014-08-07 2015-08-06 抗Ｏｒａｉ１抗体

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CY1124021T1 true CY1124021T1 (el) 2022-05-27

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US (2) US10351624B2 (el)
EP (1) EP3178931B1 (el)
JP (3) JP6125110B2 (el)
KR (1) KR102500401B1 (el)
CN (1) CN106795512B (el)
AU (1) AU2015300037C1 (el)
BR (1) BR112017002333A2 (el)
CA (1) CA2957502C (el)
CO (1) CO2017001626A2 (el)
CY (1) CY1124021T1 (el)
DK (1) DK3178931T3 (el)
ES (1) ES2861313T3 (el)
HR (1) HRP20210455T1 (el)
HU (1) HUE054148T2 (el)
IL (1) IL250475B (el)
LT (1) LT3178931T (el)
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PH (1) PH12017500217B1 (el)
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RU (1) RU2724742C2 (el)
SG (2) SG10201900862WA (el)
SI (1) SI3178931T1 (el)
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EA201990296A1 (ru) 2016-08-05 2019-08-30 Аллакос, Инк. Антитела против siglec-7 для лечения рака
WO2019140273A1 (en) * 2018-01-11 2019-07-18 Allakos, Inc. Anti-siglec-7 antibodies having reduced effector function
CN108562748A (zh) * 2018-03-28 2018-09-21 深圳承启生物科技有限公司 Orai1蛋白和/或STIM1蛋白作为脑卒中生物标志物的用途
DE102019106711A1 (de) 2019-03-15 2020-09-17 Grob-Werke Gmbh & Co. Kg Verfahren und Vorrichtung zum mehrlagigen Einfügen einer Spulenmatte in ein Bauteil einer elektrischen Maschine
CN111273015B (zh) * 2020-04-13 2023-04-11 北京维德维康生物技术有限公司 一种检测短裸甲藻毒素的酶联免疫试剂盒及其制备和应用
WO2023049867A1 (en) * 2021-09-24 2023-03-30 Seeker Biologics, Inc. Orai1 multispecific antibodies and methods of use

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EP2368912B1 (en) 2006-01-05 2017-05-03 Children's Medical Center Corporation Regulators of NFAT
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