CY1121279T1 - Ετεροκυκλικη ενωση - Google Patents
Ετεροκυκλικη ενωσηInfo
- Publication number
- CY1121279T1 CY1121279T1 CY20191100202T CY191100202T CY1121279T1 CY 1121279 T1 CY1121279 T1 CY 1121279T1 CY 20191100202 T CY20191100202 T CY 20191100202T CY 191100202 T CY191100202 T CY 191100202T CY 1121279 T1 CY1121279 T1 CY 1121279T1
- Authority
- CY
- Cyprus
- Prior art keywords
- compound
- heterocycle
- union
- salt
- medicament
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 5
- 150000003839 salts Chemical class 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 2
- 101000829153 Homo sapiens Somatostatin receptor type 5 Proteins 0.000 abstract 1
- 102100023806 Somatostatin receptor type 5 Human genes 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013224093 | 2013-10-29 | ||
| PCT/JP2014/005438 WO2015064083A1 (en) | 2013-10-29 | 2014-10-28 | Heterocyclic compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1121279T1 true CY1121279T1 (el) | 2020-05-29 |
Family
ID=51932560
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20191100202T CY1121279T1 (el) | 2013-10-29 | 2019-02-14 | Ετεροκυκλικη ενωση |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US9120777B2 (https=) |
| EP (1) | EP3063139B1 (https=) |
| JP (1) | JP6450755B2 (https=) |
| AR (2) | AR098215A1 (https=) |
| CY (1) | CY1121279T1 (https=) |
| DK (1) | DK3063139T3 (https=) |
| ES (1) | ES2710657T3 (https=) |
| HR (1) | HRP20190133T1 (https=) |
| HU (1) | HUE041792T2 (https=) |
| LT (1) | LT3063139T (https=) |
| PL (1) | PL3063139T3 (https=) |
| PT (1) | PT3063139T (https=) |
| RS (1) | RS58321B1 (https=) |
| SI (1) | SI3063139T1 (https=) |
| SM (1) | SMT201900101T1 (https=) |
| TR (1) | TR201901986T4 (https=) |
| TW (1) | TWI668214B (https=) |
| UY (1) | UY35801A (https=) |
| WO (1) | WO2015064083A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6121339B2 (ja) * | 2012-02-13 | 2017-04-26 | 武田薬品工業株式会社 | 芳香環化合物 |
| JP6247697B2 (ja) | 2013-03-14 | 2017-12-13 | 武田薬品工業株式会社 | スピロアゼチジンイソキサゾール誘導体及びそのｓｓｔｒ５アンタゴニストとしての使用 |
| JO3442B1 (ar) | 2013-10-07 | 2019-10-20 | Takeda Pharmaceuticals Co | مضادات ذات نوع فرعي من مستقبل سوماتوستاتين 5 (sstr5) |
| CN114981260A (zh) * | 2019-12-19 | 2022-08-30 | 斯特拉斯堡大学 | σ-1受体配体及其用途 |
| CN116368140A (zh) | 2020-09-10 | 2023-06-30 | 加舒布鲁姆生物公司 | 杂环glp-1激动剂 |
| CN116354961B (zh) * | 2021-12-27 | 2025-07-25 | 中国科学院上海药物研究所 | 生长抑素受体5拮抗剂及其药物组合物及用途 |
| WO2024204277A1 (ja) | 2023-03-27 | 2024-10-03 | 株式会社スコヒアファーマ | 成長ホルモン分泌促進剤 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5356906A (en) | 1989-10-27 | 1994-10-18 | The Du Pont Merck Pharmaceutical Company | (N-phthalimidoalkyl) piperidines useful as treatments for psychosis |
| ES2320973T3 (es) | 2000-06-12 | 2009-06-01 | EISAI R&D MANAGEMENT CO., LTD. | Compuestos de 1,2-dihidropiridina, procedimiento para su preparacion y uso de los mismos. |
| GB0129260D0 (en) | 2001-12-06 | 2002-01-23 | Eisai London Res Lab Ltd | Pharmaceutical compositions and their uses |
| RU2366655C2 (ru) | 2003-03-14 | 2009-09-10 | Оно Фармасьютикал Ко., Лтд. | Азотсодержащие гетероциклические производные и лекарственные средства, содержащие их в качестве активного ингредиента |
| KR20060123292A (ko) | 2003-11-10 | 2006-12-01 | 쉐링 악티엔게젤샤프트 | Ｃｃｒ-5 길항제로서 유용한 벤질에테르 아민 화합물 |
| WO2008019967A2 (en) * | 2006-08-15 | 2008-02-21 | F. Hoffmann-La Roche Ag | Phenyl, pyridine and quinoline derivatives |
| US7862825B2 (en) | 2007-02-21 | 2011-01-04 | Mladen Vranic | Method of controlling tight blood glucose by somatostatin receptor antagonists |
| US7799806B2 (en) * | 2007-04-04 | 2010-09-21 | Hoffmann-La Roche Inc. | Substituted n-benzyl piperidines as somatostatin receptor modulators |
| US20080306116A1 (en) | 2007-06-08 | 2008-12-11 | Christ Andreas D | Aryloxazole, aryloxadiazole and benzimidazole derivatives |
| TW200918062A (en) | 2007-09-12 | 2009-05-01 | Wyeth Corp | Azacyclylisoquinolinone and-isoindolinone derivatives as histamine-3 antagonists |
| JP2012526136A (ja) | 2009-05-07 | 2012-10-25 | メルク・シャープ・エンド・ドーム・コーポレイション | 抗糖尿病化合物として有用な置換スピロ環式アミン |
| WO2012024183A1 (en) | 2010-08-18 | 2012-02-23 | Merck Sharp & Dohme Corp. | Spiroxazolidinone compounds |
| WO2012069917A1 (en) | 2010-11-26 | 2012-05-31 | Lupin Limited | Bicyclic gpr119 modulators |
| JP6247697B2 (ja) | 2013-03-14 | 2017-12-13 | 武田薬品工業株式会社 | スピロアゼチジンイソキサゾール誘導体及びそのｓｓｔｒ５アンタゴニストとしての使用 |
-
2014
- 2014-10-28 AR ARP140104043A patent/AR098215A1/es active IP Right Grant
- 2014-10-28 RS RS20190190A patent/RS58321B1/sr unknown
- 2014-10-28 HU HUE14800152A patent/HUE041792T2/hu unknown
- 2014-10-28 ES ES14800152T patent/ES2710657T3/es active Active
- 2014-10-28 DK DK14800152.2T patent/DK3063139T3/en active
- 2014-10-28 TR TR2019/01986T patent/TR201901986T4/tr unknown
- 2014-10-28 WO PCT/JP2014/005438 patent/WO2015064083A1/en not_active Ceased
- 2014-10-28 US US14/525,593 patent/US9120777B2/en active Active
- 2014-10-28 PL PL14800152T patent/PL3063139T3/pl unknown
- 2014-10-28 TW TW103137143A patent/TWI668214B/zh active
- 2014-10-28 SM SM20190101T patent/SMT201900101T1/it unknown
- 2014-10-28 SI SI201431055T patent/SI3063139T1/sl unknown
- 2014-10-28 PT PT14800152T patent/PT3063139T/pt unknown
- 2014-10-28 HR HRP20190133TT patent/HRP20190133T1/hr unknown
- 2014-10-28 UY UY0001035801A patent/UY35801A/es not_active Application Discontinuation
- 2014-10-28 JP JP2016526960A patent/JP6450755B2/ja active Active
- 2014-10-28 LT LTEP14800152.2T patent/LT3063139T/lt unknown
- 2014-10-28 EP EP14800152.2A patent/EP3063139B1/en active Active
-
2019
- 2019-02-14 CY CY20191100202T patent/CY1121279T1/el unknown
-
2022
- 2022-12-29 AR ARP220103645A patent/AR128158A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US9120777B2 (en) | 2015-09-01 |
| TR201901986T4 (tr) | 2019-03-21 |
| AR098215A1 (es) | 2016-05-18 |
| AR128158A2 (es) | 2024-03-27 |
| WO2015064083A1 (en) | 2015-05-07 |
| PT3063139T (pt) | 2019-02-22 |
| TWI668214B (zh) | 2019-08-11 |
| LT3063139T (lt) | 2019-02-25 |
| RS58321B1 (sr) | 2019-03-29 |
| HRP20190133T1 (hr) | 2019-03-22 |
| EP3063139B1 (en) | 2018-11-21 |
| SMT201900101T1 (it) | 2019-02-28 |
| DK3063139T3 (en) | 2019-03-11 |
| JP2016535040A (ja) | 2016-11-10 |
| EP3063139A1 (en) | 2016-09-07 |
| HUE041792T2 (hu) | 2019-05-28 |
| US20150119412A1 (en) | 2015-04-30 |
| JP6450755B2 (ja) | 2019-01-09 |
| UY35801A (es) | 2015-06-30 |
| ES2710657T3 (es) | 2019-04-26 |
| PL3063139T3 (pl) | 2019-05-31 |
| SI3063139T1 (sl) | 2019-03-29 |
| TW201542539A (zh) | 2015-11-16 |
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