CY1121253T1 - Μεθοδος παραγωγης μεγαλης κλιμακας του διυδροχλωρικου ν-[4-(1-κυκλοβουτυλοπιπεριδιν-4-υλοξυ)φαινυλ]-2-(μορφολιν-4-υλ)ακεταμιδιου - Google Patents
Μεθοδος παραγωγης μεγαλης κλιμακας του διυδροχλωρικου ν-[4-(1-κυκλοβουτυλοπιπεριδιν-4-υλοξυ)φαινυλ]-2-(μορφολιν-4-υλ)ακεταμιδιουInfo
- Publication number
- CY1121253T1 CY1121253T1 CY20181101122T CY181101122T CY1121253T1 CY 1121253 T1 CY1121253 T1 CY 1121253T1 CY 20181101122 T CY20181101122 T CY 20181101122T CY 181101122 T CY181101122 T CY 181101122T CY 1121253 T1 CY1121253 T1 CY 1121253T1
- Authority
- CY
- Cyprus
- Prior art keywords
- yloxy
- phenyl
- cyclovutylopiperidin
- dihydrochlorate
- morfolin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Η παρούσα εφεύρεση αναφέρεται σε μια διαδικασία παραγωγής μεγάλης κλίμακας του διυδροχλωρικού Ν-[4-(1-κυκλοβουτυλοπιπεριδιν-4-υλοξυ)φαινυλ]-2-(μορφολιν-4-υλ)ακεταμιδιου του Χημικού Τύπου (I).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN4010CH2014 | 2014-08-16 | ||
| PCT/IN2014/000666 WO2016027275A1 (en) | 2014-08-16 | 2014-10-20 | Process for large scale production of n-[4-(1- cyclobutyl piperidin-4-yloxy) phenyl]-2-(morpholin-4-yl) acet amide dihydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1121253T1 true CY1121253T1 (el) | 2020-05-29 |
Family
ID=52339255
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20181101122T CY1121253T1 (el) | 2014-08-16 | 2018-10-30 | Μεθοδος παραγωγης μεγαλης κλιμακας του διυδροχλωρικου ν-[4-(1-κυκλοβουτυλοπιπεριδιν-4-υλοξυ)φαινυλ]-2-(μορφολιν-4-υλ)ακεταμιδιου |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US9802896B2 (el) |
| EP (1) | EP3180334B1 (el) |
| JP (1) | JP6385580B2 (el) |
| KR (1) | KR101860487B1 (el) |
| CN (1) | CN106573925B (el) |
| AP (1) | AP2017009753A0 (el) |
| AU (1) | AU2014403999B2 (el) |
| BR (1) | BR112017002922B1 (el) |
| CA (1) | CA2957494C (el) |
| CY (1) | CY1121253T1 (el) |
| DK (1) | DK3180334T3 (el) |
| EA (1) | EA032823B1 (el) |
| ES (1) | ES2693378T3 (el) |
| HK (1) | HK1231472A1 (el) |
| HR (1) | HRP20181801T1 (el) |
| HU (1) | HUE041465T2 (el) |
| IL (1) | IL250412B (el) |
| LT (1) | LT3180334T (el) |
| MX (1) | MX364931B (el) |
| NZ (1) | NZ728915A (el) |
| PL (1) | PL3180334T3 (el) |
| PT (1) | PT3180334T (el) |
| RS (1) | RS57927B1 (el) |
| SG (1) | SG11201701104SA (el) |
| SI (1) | SI3180334T1 (el) |
| TR (1) | TR201816175T4 (el) |
| WO (1) | WO2016027275A1 (el) |
| ZA (1) | ZA201700936B (el) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019229509A1 (en) * | 2018-05-31 | 2019-12-05 | Suven Life Sciences Limited | Method of treatment with histamine-3 receptor inverse agonist |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9904738D0 (sv) * | 1999-12-22 | 1999-12-22 | Astra Pharma Prod | Novel compounds |
| CN103415510B (zh) * | 2011-02-04 | 2016-01-13 | 庵原化学工业株式会社 | 氨苯基嘧啶基醇衍生物的制备方法及其合成中间体 |
| BR112013021496B1 (pt) * | 2011-02-23 | 2021-10-13 | Suven Life Sciences Limited | Composto, composição farmacêutica, uso da composição farmacêutica, processo para a preparação de um composto e uso do composto |
-
2014
- 2014-10-20 NZ NZ728915A patent/NZ728915A/en unknown
- 2014-10-20 WO PCT/IN2014/000666 patent/WO2016027275A1/en active Application Filing
- 2014-10-20 JP JP2017527992A patent/JP6385580B2/ja active Active
- 2014-10-20 TR TR2018/16175T patent/TR201816175T4/tr unknown
- 2014-10-20 EA EA201790388A patent/EA032823B1/ru unknown
- 2014-10-20 US US15/504,210 patent/US9802896B2/en active Active
- 2014-10-20 MX MX2017002043A patent/MX364931B/es active IP Right Grant
- 2014-10-20 CN CN201480081244.5A patent/CN106573925B/zh active Active
- 2014-10-20 SI SI201430937T patent/SI3180334T1/sl unknown
- 2014-10-20 CA CA2957494A patent/CA2957494C/en active Active
- 2014-10-20 BR BR112017002922-7A patent/BR112017002922B1/pt active IP Right Grant
- 2014-10-20 SG SG11201701104SA patent/SG11201701104SA/en unknown
- 2014-10-20 AU AU2014403999A patent/AU2014403999B2/en active Active
- 2014-10-20 LT LTEP14825190.3T patent/LT3180334T/lt unknown
- 2014-10-20 KR KR1020177005182A patent/KR101860487B1/ko active IP Right Grant
- 2014-10-20 RS RS20181306A patent/RS57927B1/sr unknown
- 2014-10-20 PT PT14825190T patent/PT3180334T/pt unknown
- 2014-10-20 EP EP14825190.3A patent/EP3180334B1/en active Active
- 2014-10-20 DK DK14825190.3T patent/DK3180334T3/en active
- 2014-10-20 PL PL14825190T patent/PL3180334T3/pl unknown
- 2014-10-20 ES ES14825190.3T patent/ES2693378T3/es active Active
- 2014-10-20 AP AP2017009753A patent/AP2017009753A0/en unknown
- 2014-10-20 HU HUE14825190A patent/HUE041465T2/hu unknown
-
2017
- 2017-02-02 IL IL25041217A patent/IL250412B/en active IP Right Grant
- 2017-02-07 ZA ZA2017/00936A patent/ZA201700936B/en unknown
- 2017-05-18 HK HK17105031.1A patent/HK1231472A1/zh unknown
-
2018
- 2018-10-30 CY CY20181101122T patent/CY1121253T1/el unknown
- 2018-10-30 HR HRP20181801TT patent/HRP20181801T1/hr unknown
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