CY1118657T1 - 6((s)-1-{1-[5-(2-yδpoξy-aiθoξy)-πypiδin-2-yλo]-1η-πypazoλ-3-yλo}-aiθyλo)-3η-1,3-βενζοθειαζολ-2-ονη) ως ενας εξαρτωμενος απο tarp γ8 ανταγωνιστης υποδοχεα αμρα - Google Patents
6((s)-1-{1-[5-(2-yδpoξy-aiθoξy)-πypiδin-2-yλo]-1η-πypazoλ-3-yλo}-aiθyλo)-3η-1,3-βενζοθειαζολ-2-ονη) ως ενας εξαρτωμενος απο tarp γ8 ανταγωνιστης υποδοχεα αμραInfo
- Publication number
- CY1118657T1 CY1118657T1 CY20171100252T CY171100252T CY1118657T1 CY 1118657 T1 CY1118657 T1 CY 1118657T1 CY 20171100252 T CY20171100252 T CY 20171100252T CY 171100252 T CY171100252 T CY 171100252T CY 1118657 T1 CY1118657 T1 CY 1118657T1
- Authority
- CY
- Cyprus
- Prior art keywords
- ylo
- tarp
- ydpoxy
- pypidin
- pipazol
- Prior art date
Links
- 235000005658 Spondias pinnata Nutrition 0.000 title 1
- 244000025012 Spondias pinnata Species 0.000 title 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 239000002464 receptor antagonist Substances 0.000 abstract 1
- 229940044551 receptor antagonist Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261730273P | 2012-11-27 | 2012-11-27 | |
| PCT/US2013/070885 WO2014085153A1 (en) | 2012-11-27 | 2013-11-20 | 6-((s)-1-{1-[5-(2-hydroxy-ethoxy)-pyridin-2-yl]-1h-pyrazol-3-yl}- ethyl)-3h-1,3-benzothiazol-2-one as a tarp-gamma 8 dependent ampa receptor antagonist |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1118657T1 true CY1118657T1 (el) | 2017-07-12 |
Family
ID=49753484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20171100252T CY1118657T1 (el) | 2012-11-27 | 2017-02-24 | 6((s)-1-{1-[5-(2-yδpoξy-aiθoξy)-πypiδin-2-yλo]-1η-πypazoλ-3-yλo}-aiθyλo)-3η-1,3-βενζοθειαζολ-2-ονη) ως ενας εξαρτωμενος απο tarp γ8 ανταγωνιστης υποδοχεα αμρα |
Country Status (35)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201609719A (zh) * | 2014-05-28 | 2016-03-16 | 美國禮來大藥廠 | 作為ＴＡＲＰ－γ８依賴性ＡＭＰＡ受體拮抗劑之６－經取代－３Ｈ－１，３－苯并噻唑－２－酮化合物 |
| HRP20210403T1 (hr) | 2015-04-29 | 2021-10-29 | Janssen Pharmaceutica Nv | Azabenzimidazoli i njihova uporaba kao modulatora ampa receptora |
| AU2016255431B2 (en) | 2015-04-29 | 2020-05-07 | Janssen Pharmaceutica Nv | Imidazopyrazines and pyrazolopyrimidines and their use as AMPA receptor modulators |
| ES2767707T3 (es) | 2015-04-29 | 2020-06-18 | Janssen Pharmaceutica Nv | Compuestos de indolona y su uso como moduladores de receptor AMPA |
| WO2016176449A1 (en) * | 2015-04-29 | 2016-11-03 | Janssen Pharmaceutica Nv | Benzimidazolone and benzothiazolone compounds and their use as ampa receptor modulators |
| JP6953527B2 (ja) * | 2016-10-26 | 2021-10-27 | ヤンセン ファーマシューティカ エヌ．ベー． | 縮合二環ピリジン化合物、及びａｍｐａ受容体調節因子としてのそれらの使用 |
| RU2650523C1 (ru) | 2017-07-24 | 2018-04-16 | федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) | Производное пиридоксина для лечения эпилепсии |
| RU2703286C1 (ru) * | 2019-06-18 | 2019-10-16 | федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) | Соли (5-гидрокси-3,4-бис(гидроксиметил)-6-метилпиридин-2-ил)метансульфокислоты и способ их получения |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY132385A (en) * | 1995-08-31 | 2007-10-31 | Novartis Ag | 2,3-dioxo-1,2,3,4-tetrahydro-quinoxalinyl derivatives |
| JP2000281676A (ja) * | 1999-01-25 | 2000-10-10 | Yamanouchi Pharmaceut Co Ltd | Ａｍｐａ拮抗化合物の新規製造法 |
| PT1300396E (pt) * | 2000-06-12 | 2009-04-20 | Eisai R&D Man Co Ltd | Compostos de 1,2-di-hidropiridina, processos para a sua preparação e sua utilização |
| US8995993B2 (en) * | 2000-10-11 | 2015-03-31 | Gogo Llc | System for managing mobile internet protocol addresses in an airborne wireless cellular network |
| CN101072775A (zh) * | 2004-12-17 | 2007-11-14 | 伊莱利利公司 | 新的mch受体拮抗剂 |
| WO2007076161A2 (en) | 2005-12-27 | 2007-07-05 | Myriad Genetics, Inc | Compounds with therapeutic activity |
| TW200817385A (en) * | 2006-07-04 | 2008-04-16 | Organon Nv | Heterocyclic derivatives |
| JP2012505198A (ja) * | 2008-10-08 | 2012-03-01 | ファイザー・インク | Ｃｎｓ障害を治療する際にａｍｐａ調節剤として使用するためのテトラヒドロフラニルスルホンアミド |
| HUE025013T2 (hu) * | 2009-01-12 | 2016-04-28 | Pfizer Ltd | Szulfonamid-származékok |
| EP2576544A4 (en) * | 2010-06-01 | 2013-09-11 | Angion Biomedica Corp | INHIBITORS OF CYTOCHROMES P450 AND USES THEREOF |
| WO2012137982A2 (en) * | 2011-04-05 | 2012-10-11 | Takeda Pharmaceutical Company Limited | Sulfonamide derivative and use thereof |
| TW201609719A (zh) | 2014-05-28 | 2016-03-16 | 美國禮來大藥廠 | 作為ＴＡＲＰ－γ８依賴性ＡＭＰＡ受體拮抗劑之６－經取代－３Ｈ－１，３－苯并噻唑－２－酮化合物 |
-
2013
- 2013-11-17 JO JOP/2013/0331A patent/JO3225B1/ar active
- 2013-11-18 TW TW106144388A patent/TW201825484A/zh unknown
- 2013-11-18 TW TW102141949A patent/TWI618705B/zh not_active IP Right Cessation
- 2013-11-18 AR ARP130104242A patent/AR093527A1/es unknown
- 2013-11-20 ES ES13802786.7T patent/ES2618260T3/es active Active
- 2013-11-20 PL PL13802786T patent/PL2925754T3/pl unknown
- 2013-11-20 PE PE2015000694A patent/PE20151728A1/es active IP Right Grant
- 2013-11-20 KR KR1020157013470A patent/KR101693133B1/ko active Active
- 2013-11-20 EA EA201590823A patent/EA026686B1/ru not_active IP Right Cessation
- 2013-11-20 JP JP2015545099A patent/JP6246227B2/ja active Active
- 2013-11-20 SI SI201330464A patent/SI2925754T1/sl unknown
- 2013-11-20 BR BR112015011200A patent/BR112015011200A2/pt not_active IP Right Cessation
- 2013-11-20 AP AP2015008489A patent/AP2015008489A0/xx unknown
- 2013-11-20 UA UAA201504865A patent/UA114345C2/uk unknown
- 2013-11-20 PT PT138027867T patent/PT2925754T/pt unknown
- 2013-11-20 DK DK13802786.7T patent/DK2925754T3/en active
- 2013-11-20 MX MX2015006697A patent/MX356478B/es active IP Right Grant
- 2013-11-20 US US14/084,683 patent/US8765960B2/en active Active
- 2013-11-20 SG SG11201504164VA patent/SG11201504164VA/en unknown
- 2013-11-20 CA CA2889243A patent/CA2889243C/en active Active
- 2013-11-20 HU HUE13802786A patent/HUE033447T2/en unknown
- 2013-11-20 MY MYPI2015701544A patent/MY177721A/en unknown
- 2013-11-20 CN CN201380061495.2A patent/CN104797578B/zh active Active
- 2013-11-20 AU AU2013352594A patent/AU2013352594B2/en active Active
- 2013-11-20 MA MA38126A patent/MA38126B1/fr unknown
- 2013-11-20 EP EP13802786.7A patent/EP2925754B1/en active Active
- 2013-11-20 HR HRP20170274TT patent/HRP20170274T1/hr unknown
- 2013-11-20 WO PCT/US2013/070885 patent/WO2014085153A1/en not_active Ceased
-
2015
- 2015-05-14 IL IL238831A patent/IL238831B/en not_active IP Right Cessation
- 2015-05-14 DO DO2015000113A patent/DOP2015000113A/es unknown
- 2015-05-20 CR CR20150267A patent/CR20150267A/es unknown
- 2015-05-22 TN TNP2015000200A patent/TN2015000200A1/fr unknown
- 2015-05-25 PH PH12015501154A patent/PH12015501154B1/en unknown
- 2015-05-26 CL CL2015001419A patent/CL2015001419A1/es unknown
- 2015-05-26 ZA ZA2015/03733A patent/ZA201503733B/en unknown
-
2017
- 2017-02-24 CY CY20171100252T patent/CY1118657T1/el unknown
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