CY1118603T1 - Δοτες νιτροξυλιου για τη θεραπευτικη αγωγη πνευμονικης υπερτασης - Google Patents

Δοτες νιτροξυλιου για τη θεραπευτικη αγωγη πνευμονικης υπερτασης

Info

Publication number
CY1118603T1
CY1118603T1 CY20171100169T CY171100169T CY1118603T1 CY 1118603 T1 CY1118603 T1 CY 1118603T1 CY 20171100169 T CY20171100169 T CY 20171100169T CY 171100169 T CY171100169 T CY 171100169T CY 1118603 T1 CY1118603 T1 CY 1118603T1
Authority
CY
Cyprus
Prior art keywords
pulmonary hypertension
treatment
nitroxyl donors
methods
donors
Prior art date
Application number
CY20171100169T
Other languages
Greek (el)
English (en)
Inventor
Vincent J Kalish
Reza Mazhari
Original Assignee
Cardioxyl Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cardioxyl Pharmaceuticals, Inc. filed Critical Cardioxyl Pharmaceuticals, Inc.
Publication of CY1118603T1 publication Critical patent/CY1118603T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CY20171100169T 2009-11-23 2017-02-07 Δοτες νιτροξυλιου για τη θεραπευτικη αγωγη πνευμονικης υπερτασης CY1118603T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26369809P 2009-11-23 2009-11-23
US26412909P 2009-11-24 2009-11-24
PCT/US2010/057844 WO2011063400A1 (en) 2009-11-23 2010-11-23 Nitroxyl donors for the treatment of pulmonary hypertension

Publications (1)

Publication Number Publication Date
CY1118603T1 true CY1118603T1 (el) 2017-07-12

Family

ID=43513876

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20171100169T CY1118603T1 (el) 2009-11-23 2017-02-07 Δοτες νιτροξυλιου για τη θεραπευτικη αγωγη πνευμονικης υπερτασης

Country Status (15)

Country Link
US (2) US20110160200A1 (OSRAM)
EP (1) EP2504003B1 (OSRAM)
JP (2) JP2013511556A (OSRAM)
CY (1) CY1118603T1 (OSRAM)
DK (1) DK2504003T3 (OSRAM)
ES (1) ES2611852T3 (OSRAM)
HR (1) HRP20170183T1 (OSRAM)
HU (1) HUE032253T2 (OSRAM)
LT (1) LT2504003T (OSRAM)
PL (1) PL2504003T3 (OSRAM)
PT (1) PT2504003T (OSRAM)
RS (1) RS55697B1 (OSRAM)
SI (1) SI2504003T1 (OSRAM)
SM (2) SMT201700090T1 (OSRAM)
WO (2) WO2011063339A1 (OSRAM)

Families Citing this family (12)

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Publication number Priority date Publication date Assignee Title
JP5832447B2 (ja) 2009-12-07 2015-12-16 ザ ジョンズ ホプキンス ユニバーシティ ビスアシル化ヒドロキシルアミン誘導体
CA2782110A1 (en) * 2009-12-07 2011-06-16 Johns Hopkins University N-acyloxysulfonamide and n-hydroxy-n-acylsulfonamide derivatives
HK1200168A1 (en) 2011-10-17 2015-07-31 The Johns Hopkins University Meldrum 's acid, barbituric acid and pyrazolone derivatives substituted with hydroxylamine as hno donors
PT2945620T (pt) 2013-01-18 2018-02-21 Cardioxyl Pharmaceuticals Inc Dadores de nitroxilo com índice terapêutico melhorado
ES2563902T3 (es) * 2013-05-14 2016-03-16 Active Biotech Ab Derivados de N-(heteroaril)-sulfonamida útiles como inhibidores de S100
ES2734060T3 (es) 2014-01-17 2019-12-04 Cardioxyl Pharmaceuticals Inc Donadores de nitroxilo de N-hidroximetanosulfonamida
US9682938B2 (en) 2014-05-27 2017-06-20 Cardioxyl Pharmaceuticals, Inc. Pyrazolone derivatives as nitroxyl donors
US9464061B2 (en) 2014-05-27 2016-10-11 The Johns Hopkins University N-hydroxylamino-barbituric acid derivatives
JP6889704B2 (ja) 2015-10-19 2021-06-18 カルディオキシル ファーマシューティカルズ，インク． ニトロキシルドナーとしてのピラゾロン誘導体
KR20180070672A (ko) 2015-10-19 2018-06-26 카르디옥실 파마슈티칼스 인코포레이티드 니트록실 공여자로서의 n-히드록실술폰아미드 유도체
KR20190070912A (ko) 2016-07-28 2019-06-21 더 존스 홉킨스 유니버시티 O-치환된 히드록삼산
US11083704B2 (en) 2017-01-03 2021-08-10 Bristol-Myers Squibb Company Method of administering nitroxyl donating compounds

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Also Published As

Publication number Publication date
US20110160200A1 (en) 2011-06-30
PL2504003T3 (pl) 2017-04-28
WO2011063400A1 (en) 2011-05-26
WO2011063339A1 (en) 2011-05-26
HRP20170183T1 (hr) 2017-03-24
SI2504003T1 (sl) 2017-01-31
DK2504003T3 (en) 2017-02-20
EP2504003B1 (en) 2016-11-09
ES2611852T3 (es) 2017-05-10
US20160081951A1 (en) 2016-03-24
HUE032253T2 (en) 2017-09-28
JP2013511556A (ja) 2013-04-04
SMT201700090B (it) 2017-03-08
PT2504003T (pt) 2017-01-31
JP2016128481A (ja) 2016-07-14
LT2504003T (lt) 2017-01-25
RS55697B1 (sr) 2017-07-31
EP2504003A1 (en) 2012-10-03
SMT201700090T1 (it) 2017-03-08

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