CY1116683T1 - Φαρμακο το οποιο περιεχει ενα παραγωγο καρβοστυριλιου και δονεπεζιλη για τη θεραπεια της νοσου alzheimer - Google Patents

Φαρμακο το οποιο περιεχει ενα παραγωγο καρβοστυριλιου και δονεπεζιλη για τη θεραπεια της νοσου alzheimer

Info

Publication number
CY1116683T1
CY1116683T1 CY20151100797T CY151100797T CY1116683T1 CY 1116683 T1 CY1116683 T1 CY 1116683T1 CY 20151100797 T CY20151100797 T CY 20151100797T CY 151100797 T CY151100797 T CY 151100797T CY 1116683 T1 CY1116683 T1 CY 1116683T1
Authority
CY
Cyprus
Prior art keywords
treatment
donespezil
carbosyril
product
alzheimer disease
Prior art date
Application number
CY20151100797T
Other languages
Greek (el)
English (en)
Inventor
Heii Arai
Original Assignee
Otsuka Pharmaceutical Co., Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co., Ltd filed Critical Otsuka Pharmaceutical Co., Ltd
Publication of CY1116683T1 publication Critical patent/CY1116683T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CY20151100797T 2007-05-22 2015-09-14 Φαρμακο το οποιο περιεχει ενα παραγωγο καρβοστυριλιου και δονεπεζιλη για τη θεραπεια της νοσου alzheimer CY1116683T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007135367 2007-05-22
EP08764779.8A EP2157973B1 (en) 2007-05-22 2008-05-21 A medicament comprising a carbostyril derivative and donepezil for treating alzheimer's disease

Publications (1)

Publication Number Publication Date
CY1116683T1 true CY1116683T1 (el) 2017-03-15

Family

ID=39636992

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20151100797T CY1116683T1 (el) 2007-05-22 2015-09-14 Φαρμακο το οποιο περιεχει ενα παραγωγο καρβοστυριλιου και δονεπεζιλη για τη θεραπεια της νοσου alzheimer

Country Status (27)

Country Link
US (1) US20100298375A1 (https=)
EP (2) EP2937085B1 (https=)
JP (1) JP5153870B2 (https=)
KR (1) KR101441725B1 (https=)
CN (1) CN101754758B (https=)
AR (1) AR066664A1 (https=)
AU (1) AU2008253977B2 (https=)
BR (1) BRPI0811919A2 (https=)
CA (1) CA2687289C (https=)
CO (1) CO6251249A2 (https=)
CY (1) CY1116683T1 (https=)
DK (1) DK2157973T3 (https=)
ES (1) ES2545959T3 (https=)
HR (1) HRP20150843T1 (https=)
HU (1) HUE025902T2 (https=)
IL (1) IL202053A (https=)
MX (1) MX2009012583A (https=)
MY (1) MY146407A (https=)
NZ (1) NZ581099A (https=)
PL (1) PL2157973T3 (https=)
PT (1) PT2157973E (https=)
RU (1) RU2469723C2 (https=)
SI (1) SI2157973T1 (https=)
TW (2) TWI489983B (https=)
UA (1) UA96633C2 (https=)
WO (1) WO2008143361A1 (https=)
ZA (1) ZA200908202B (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2135607A1 (en) 2008-06-18 2009-12-23 Pharnext Combination of pilocarpin and methimazol for treating Charcot-MarieTooth disease and related disorders
US9387206B2 (en) 2009-11-03 2016-07-12 Pharnext Therapeutic approaches for treating Alzheimer's disease
EP2322163A1 (en) * 2009-11-03 2011-05-18 Pharnext New therapeutics approaches for treating alzheimer disease
US9241933B2 (en) 2011-03-01 2016-01-26 Pharnext Compositions for treating amyotrophic lateral sclerosis
US10010515B2 (en) 2011-03-01 2018-07-03 Pharnext Therapeutic approaches for treating Parkinson's disease
TR201809351T4 (tr) 2011-03-01 2018-07-23 Pharnext Nörolojik bozuklukların baklofen ve akamprosat tabanlı terapisi.
US9248111B2 (en) 2011-03-01 2016-02-02 Pharnext Therapeutic approaches for treating parkinson's disease
KR20150027800A (ko) * 2012-06-15 2015-03-12 고에키 자이단 호징 센탄 이료 신코 자이단 경도 인지 장해의 예방 및/또는 치료제
WO2015100255A2 (en) * 2013-12-23 2015-07-02 Holaday John W Disposable container for air hydration
WO2017199755A1 (ja) * 2016-05-19 2017-11-23 国立研究開発法人国立循環器病研究センター 認知症の予防及び／又は治療のための薬剤
MX385719B (es) 2017-05-24 2025-03-18 H Lundbeck As Combinacion de un antagonista del receptor 5-ht6 y un inhibidor de acetilcolinesterasa para su uso en el tratamiento de la enfermedad de alzheimer en una subpoblacion de pacientes portadores de alelos apoe4
CN107602523B (zh) * 2017-09-11 2020-08-18 安徽中医药大学 京尼平类似物、制备方法及其应用
PL237739B1 (pl) 2018-06-06 2021-05-17 Univ Gdanski Genisteina do zastosowania do leczenia choroby Alzheimera
NL2024431B1 (en) 2019-12-11 2021-09-07 Sulfateq Bv Compounds for treatment of alzheimer’s disease

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5535019A (en) 1978-09-01 1980-03-11 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
JPS5649378A (en) 1979-08-25 1981-05-02 Otsuka Pharmaceut Co Ltd Tetrazolylalkoxycarbostyril derivative
FI95572C (fi) 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
JP2574099B2 (ja) 1992-05-21 1997-01-22 大塚製薬株式会社 アレルギー疾患治療剤
JPH10175864A (ja) 1996-12-16 1998-06-30 Otsuka Pharmaceut Co Ltd 慢性閉塞性肺疾患治療剤
US6019735A (en) * 1997-08-28 2000-02-01 Visco Technologies, Inc. Viscosity measuring apparatus and method of use
US6322524B1 (en) * 1997-08-28 2001-11-27 Visco Technologies, Inc. Dual riser/single capillary viscometer
US6322525B1 (en) * 1997-08-28 2001-11-27 Visco Technologies, Inc. Method of analyzing data from a circulating blood viscometer for determining absolute and effective blood viscosity
US6428488B1 (en) * 1997-08-28 2002-08-06 Kenneth Kensey Dual riser/dual capillary viscometer for newtonian and non-newtonian fluids
EP1047674B1 (en) * 1998-01-16 2005-03-30 Eisai Co., Ltd. Process for production of donepezil derivatives
US6187790B1 (en) * 1999-03-04 2001-02-13 Neal R. Cutler Use of cilostazol for treatment of sexual dysfunction
US6267985B1 (en) * 1999-06-30 2001-07-31 Lipocine Inc. Clear oil-containing pharmaceutical compositions
US6294192B1 (en) * 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US6484565B2 (en) * 1999-11-12 2002-11-26 Drexel University Single riser/single capillary viscometer using mass detection or column height detection
US6458804B1 (en) * 2001-01-26 2002-10-01 R.T. Alamo Venturesi, Llc Methods for the treatment of central nervous system disorders in certain patient groups
TW200301135A (en) * 2001-12-27 2003-07-01 Otsuka Maryland Res Inst Inc Pharmaceutical compositions comprising a multifunctional phosphodiesterase inhibitor and an adenosine uptake inhibitor
IL150509A (en) * 2002-07-01 2007-07-04 Joseph Kaspi Pharmaceutical preparations containing donafazil hydrochloride
US6743806B2 (en) * 2002-10-23 2004-06-01 Otsuka Pharmaceutical Company, Limited Active oxygen scavenger
FR2848452B1 (fr) * 2002-12-12 2007-04-06 Aventis Pharma Sa Application des inhibiteurs de recapture intestinale des acides biliaires pour la prevention et le traitement de la maladie d'alzheimer
JP2004189706A (ja) * 2002-12-13 2004-07-08 Eisai Co Ltd 高度アルツハイマー型痴呆治療剤
TWI323660B (en) * 2003-02-25 2010-04-21 Otsuka Pharma Co Ltd Pten inhibitor or maxi-k channels opener

Also Published As

Publication number Publication date
RU2469723C2 (ru) 2012-12-20
DK2157973T3 (en) 2015-08-17
SI2157973T1 (sl) 2015-10-30
TW201412315A (zh) 2014-04-01
CA2687289A1 (en) 2008-11-27
IL202053A0 (en) 2010-06-16
HK1140422A1 (en) 2010-10-15
EP2157973B1 (en) 2015-07-15
HK1215384A1 (en) 2016-08-26
PL2157973T3 (pl) 2015-12-31
HUE025902T2 (en) 2016-05-30
TW200904428A (en) 2009-02-01
ES2545959T3 (es) 2015-09-17
JP5153870B2 (ja) 2013-02-27
PT2157973E (pt) 2015-10-14
HRP20150843T1 (hr) 2015-09-11
CO6251249A2 (es) 2011-02-21
EP2937085B1 (en) 2019-07-10
ZA200908202B (en) 2010-07-28
CN101754758B (zh) 2012-10-24
US20100298375A1 (en) 2010-11-25
UA96633C2 (uk) 2011-11-25
IL202053A (en) 2016-04-21
CA2687289C (en) 2015-09-15
EP2157973A1 (en) 2010-03-03
AU2008253977A1 (en) 2008-11-27
WO2008143361A1 (en) 2008-11-27
TWI489983B (zh) 2015-07-01
NZ581099A (en) 2012-03-30
BRPI0811919A2 (pt) 2014-11-18
AU2008253977B2 (en) 2013-08-22
MX2009012583A (es) 2010-03-08
MY146407A (en) 2012-08-15
AR066664A1 (es) 2009-09-02
KR20100020482A (ko) 2010-02-22
KR101441725B1 (ko) 2014-09-18
EP2937085A1 (en) 2015-10-28
CN101754758A (zh) 2010-06-23
RU2009147456A (ru) 2011-06-27
TWI423802B (zh) 2014-01-21
JP2010527993A (ja) 2010-08-19

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