CY1112527T1 - Συνθεσεις που περιεχουν αμιοdαrονε και sulfoalkyl ether cyclodextrin - Google Patents

Συνθεσεις που περιεχουν αμιοdαrονε και sulfoalkyl ether cyclodextrin

Info

Publication number
CY1112527T1
CY1112527T1 CY20121100190T CY121100190T CY1112527T1 CY 1112527 T1 CY1112527 T1 CY 1112527T1 CY 20121100190 T CY20121100190 T CY 20121100190T CY 121100190 T CY121100190 T CY 121100190T CY 1112527 T1 CY1112527 T1 CY 1112527T1
Authority
CY
Cyprus
Prior art keywords
amiodarone
cyclodextrin
compositions
sulfoalkyl ether
composition
Prior art date
Application number
CY20121100190T
Other languages
Greek (el)
English (en)
Inventor
Gerold L Mosher
Karen T Johnson
Atef A Gayed
Original Assignee
Cydex Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cydex Pharmaceuticals, Inc. filed Critical Cydex Pharmaceuticals, Inc.
Publication of CY1112527T1 publication Critical patent/CY1112527T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/724Cyclodextrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0006Skin tests, e.g. intradermal testing, test strips, delayed hypersensitivity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nanotechnology (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
CY20121100190T 2002-05-04 2012-02-23 Συνθεσεις που περιεχουν αμιοdαrονε και sulfoalkyl ether cyclodextrin CY1112527T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/139,620 US6869939B2 (en) 2002-05-04 2002-05-04 Formulations containing amiodarone and sulfoalkyl ether cyclodextrin
EP03728598A EP1501496B1 (en) 2002-05-04 2003-04-29 Formulations containing amiodarone and sulfoalkyl ether cyclodextrin

Publications (1)

Publication Number Publication Date
CY1112527T1 true CY1112527T1 (el) 2015-12-09

Family

ID=29399340

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20121100190T CY1112527T1 (el) 2002-05-04 2012-02-23 Συνθεσεις που περιεχουν αμιοdαrονε και sulfoalkyl ether cyclodextrin

Country Status (16)

Country Link
US (1) US6869939B2 (enExample)
EP (2) EP1501496B1 (enExample)
JP (2) JP4764004B2 (enExample)
KR (1) KR100984197B1 (enExample)
AT (1) ATE535239T1 (enExample)
AU (1) AU2003234285B2 (enExample)
CA (1) CA2483774C (enExample)
CY (1) CY1112527T1 (enExample)
DK (2) DK2402008T3 (enExample)
ES (2) ES2378306T3 (enExample)
HU (1) HUE027551T2 (enExample)
IL (2) IL165022A0 (enExample)
MX (1) MXPA04010925A (enExample)
PT (1) PT1501496E (enExample)
SI (2) SI1501496T1 (enExample)
WO (1) WO2003092590A2 (enExample)

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PH12012502454A1 (en) * 2010-06-11 2013-02-18 Baxter Healthcare Sa Formulations including amiodarone and salts thereof and methods of their manufacture and use
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PT3702374T (pt) 2012-02-15 2022-06-23 Cydex Pharmaceuticals Inc Processo de fabrico para derivados de ciclodextrina
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JP6557144B2 (ja) 2012-10-22 2019-08-07 サイデックス・ファーマシューティカルズ・インコーポレイテッド アルキル化シクロデキストリン組成物ならびにその調製方法および使用方法
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Also Published As

Publication number Publication date
SI1501496T1 (sl) 2012-04-30
AU2003234285A1 (en) 2003-11-17
ATE535239T1 (de) 2011-12-15
US6869939B2 (en) 2005-03-22
EP1501496B1 (en) 2011-11-30
DK1501496T3 (da) 2012-03-19
EP2402008B1 (en) 2016-01-27
HUE027551T2 (en) 2016-10-28
IL165022A (en) 2011-08-31
JP2005530744A (ja) 2005-10-13
CA2483774A1 (en) 2003-11-13
EP2402008A1 (en) 2012-01-04
DK2402008T3 (en) 2016-05-02
US20030216353A1 (en) 2003-11-20
KR20040106452A (ko) 2004-12-17
JP2011116776A (ja) 2011-06-16
EP1501496A4 (en) 2006-05-31
ES2378306T3 (es) 2012-04-11
SI2402008T1 (sl) 2016-05-31
WO2003092590A3 (en) 2004-01-22
WO2003092590A2 (en) 2003-11-13
PT1501496E (pt) 2012-02-20
IL165022A0 (en) 2005-12-18
ES2567716T3 (es) 2016-04-26
AU2003234285B2 (en) 2007-01-04
EP1501496A2 (en) 2005-02-02
JP5656692B2 (ja) 2015-01-21
CA2483774C (en) 2011-07-19
KR100984197B1 (ko) 2010-09-28
MXPA04010925A (es) 2005-02-14
JP4764004B2 (ja) 2011-08-31

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