CY1112103T1 - Αντιογκικες ενωσεις διϋδροπυραν-2-ονης - Google Patents

Αντιογκικες ενωσεις διϋδροπυραν-2-ονης

Info

Publication number
CY1112103T1
CY1112103T1 CY20111101175T CY111101175T CY1112103T1 CY 1112103 T1 CY1112103 T1 CY 1112103T1 CY 20111101175 T CY20111101175 T CY 20111101175T CY 111101175 T CY111101175 T CY 111101175T CY 1112103 T1 CY1112103 T1 CY 1112103T1
Authority
CY
Cyprus
Prior art keywords
dirodypiran
ony
antique
compounds
lithistoides
Prior art date
Application number
CY20111101175T
Other languages
Greek (el)
English (en)
Inventor
LÓPEZ Mª JESÚS MARTÍN
Molinero Laura Coello
Benítez José Fernando Reyes
Vicente Alberto Rodríguez
Garcla-Ibarrola Maria Garranzo
Pérez Carmen Murcia
Solloso Andrés Francesch
Sancho Francisco Sánchez
Marchante Maria Del Carmen Cuevas
Rodríguez Rogelio Fernández
Original Assignee
Pharma Mar, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharma Mar, S.A. filed Critical Pharma Mar, S.A.
Publication of CY1112103T1 publication Critical patent/CY1112103T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
CY20111101175T 2006-06-16 2011-11-30 Αντιογκικες ενωσεις διϋδροπυραν-2-ονης CY1112103T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06380173 2006-06-16
EP07765445A EP2032551B9 (en) 2006-06-16 2007-06-15 Antitumoral dihydropyran-2-one compounds

Publications (1)

Publication Number Publication Date
CY1112103T1 true CY1112103T1 (el) 2015-11-04

Family

ID=38508885

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20111101175T CY1112103T1 (el) 2006-06-16 2011-11-30 Αντιογκικες ενωσεις διϋδροπυραν-2-ονης

Country Status (29)

Country Link
US (2) US8324406B2 (enExample)
EP (3) EP2404913A3 (enExample)
JP (2) JP5117491B2 (enExample)
KR (1) KR101474031B1 (enExample)
CN (2) CN102336730A (enExample)
AR (1) AR061506A1 (enExample)
AT (1) ATE522514T1 (enExample)
AU (1) AU2007259257B8 (enExample)
BR (2) BRPI0713031B8 (enExample)
CA (1) CA2654334C (enExample)
CY (1) CY1112103T1 (enExample)
DK (1) DK2032551T3 (enExample)
ES (1) ES2371942T3 (enExample)
HR (1) HRP20110845T1 (enExample)
IL (1) IL195676A (enExample)
MX (1) MX2008015754A (enExample)
MY (1) MY145788A (enExample)
NO (2) NO341508B1 (enExample)
NZ (1) NZ573706A (enExample)
PL (1) PL2032551T3 (enExample)
PT (1) PT2032551E (enExample)
RS (1) RS52034B (enExample)
RU (2) RU2444519C2 (enExample)
SG (1) SG174830A1 (enExample)
SI (1) SI2032551T1 (enExample)
TW (2) TWI373469B (enExample)
UA (1) UA97369C2 (enExample)
WO (1) WO2007144423A1 (enExample)
ZA (1) ZA200810315B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2597091B1 (en) 2007-12-20 2016-04-20 Pharma Mar, S.A. Antitumoral Compounds
MX2010008922A (es) 2008-02-20 2010-09-07 Actelion Pharmaceuticals Ltd Compuestos antibioticos azatriciclicos.
ES2398939T3 (es) 2008-02-22 2013-03-22 Actelion Pharmaceuticals Ltd. Derivados de oxazolidinona
MY158520A (en) 2008-10-07 2016-10-14 Actelion Pharmaceuticals Ltd Tricyclic oxazolidinone antibiotic compounds
BRPI0920870A2 (pt) 2008-10-10 2018-06-26 Actelion Pharmaceuticals Ltd antibióticos de oxazolidinila.
WO2010149688A2 (en) 2009-06-24 2010-12-29 Pharma Mar, S.A. Antitumoral compounds
GB201309807D0 (en) * 2013-05-31 2013-07-17 Pharma Mar Sau Antibody drug conjugates
CN108467378A (zh) * 2017-02-23 2018-08-31 复旦大学 一种二氢吡喃酮类化合物及其制备方法和用途
JOP20190254A1 (ar) 2017-04-27 2019-10-27 Pharma Mar Sa مركبات مضادة للأورام
CN110790737B (zh) * 2019-11-07 2022-07-22 河南中烟工业有限责任公司 一种2,3-二氢-3,5-二羟基-6-乙基-4h-吡喃-4-酮的制备方法
TW202330486A (zh) 2021-10-22 2023-08-01 西班牙商瑪製藥股份有限公司 抗腫瘤化合物
CN117510448A (zh) * 2023-11-13 2024-02-06 贵州中医药大学 一种二氢吡喃酮衍生物及其制备方法与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA938019B (en) * 1992-11-13 1995-04-28 Upjohn Co Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating HIV and other retroviruses
PT1142887E (pt) * 1993-11-19 2004-08-31 Parke Davis & Co Derivados de 5,6-di-hidropirona como inibidores de protease e agentes antivirais
US7446196B2 (en) * 2004-06-03 2008-11-04 Kosan Biosciences, Incorporated Leptomycin compounds

Also Published As

Publication number Publication date
US20090186938A1 (en) 2009-07-23
NO20111248L (no) 2008-12-16
HK1130052A1 (en) 2009-12-18
EP2404912A3 (en) 2012-07-25
NZ573706A (en) 2011-09-30
CA2654334A1 (en) 2007-12-21
WO2007144423A1 (en) 2007-12-21
AU2007259257A8 (en) 2012-04-05
JP5117491B2 (ja) 2013-01-16
KR101474031B1 (ko) 2014-12-17
AR061506A1 (es) 2008-09-03
JP2012021023A (ja) 2012-02-02
HRP20110845T1 (hr) 2011-12-31
SG174830A1 (en) 2011-10-28
BRPI0713031B1 (pt) 2020-10-06
UA97369C2 (ru) 2012-02-10
EP2404913A2 (en) 2012-01-11
KR20090024261A (ko) 2009-03-06
NO20090054L (no) 2009-01-06
ATE522514T1 (de) 2011-09-15
CN101679340B (zh) 2013-06-05
MX2008015754A (es) 2009-01-12
RU2011133128A (ru) 2013-02-10
IL195676A0 (en) 2009-09-01
TW200811128A (en) 2008-03-01
US8501968B2 (en) 2013-08-06
PT2032551E (pt) 2011-12-06
CN102336730A (zh) 2012-02-01
DK2032551T3 (da) 2012-01-02
US20120190870A1 (en) 2012-07-26
TWI373469B (en) 2012-10-01
RU2009101150A (ru) 2010-07-27
ES2371942T3 (es) 2012-01-11
US20100048690A2 (en) 2010-02-25
EP2032551B1 (en) 2011-08-31
AU2007259257A1 (en) 2007-12-21
SI2032551T1 (sl) 2012-01-31
BRPI0722429A2 (pt) 2013-11-26
US8324406B2 (en) 2012-12-04
AU2007259257B8 (en) 2012-04-05
BRPI0713031A2 (pt) 2013-03-12
CA2654334C (en) 2014-06-10
PL2032551T3 (pl) 2012-01-31
MY145788A (en) 2012-04-30
EP2404912A2 (en) 2012-01-11
EP2404913A3 (en) 2012-06-06
EP2032551A1 (en) 2009-03-11
ZA200810315B (en) 2010-02-24
BRPI0713031B8 (pt) 2021-05-25
TW201213316A (en) 2012-04-01
EP2032551B9 (en) 2012-02-29
RS52034B (sr) 2012-04-30
IL195676A (en) 2012-06-28
CN101679340A (zh) 2010-03-24
RU2444519C2 (ru) 2012-03-10
NO341508B1 (no) 2017-11-27
JP2009539943A (ja) 2009-11-19
AU2007259257B2 (en) 2011-12-08

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