CY1111735T1 - Ιατρικο προϊον περιλαμβανον τιοτροπιο σε ενα υδατοστεγες δοχειο - Google Patents
Ιατρικο προϊον περιλαμβανον τιοτροπιο σε ενα υδατοστεγες δοχειοInfo
- Publication number
- CY1111735T1 CY1111735T1 CY20111100727T CY111100727T CY1111735T1 CY 1111735 T1 CY1111735 T1 CY 1111735T1 CY 20111100727 T CY20111100727 T CY 20111100727T CY 111100727 T CY111100727 T CY 111100727T CY 1111735 T1 CY1111735 T1 CY 1111735T1
- Authority
- CY
- Cyprus
- Prior art keywords
- dose
- tiotropium
- moisture
- container
- medical product
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4748—Quinolines; Isoquinolines forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Otolaryngology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Packages (AREA)
- Materials For Medical Uses (AREA)
- Table Devices Or Equipment (AREA)
- Containers Having Bodies Formed In One Piece (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Η εφεύρεση αποκαλύπτει ένα ιατρικό προϊόν για χρήση στην αγωγή αναπνευστικών διαταραχών, και περιλαμβάνει μία μετρική δόση συστάσεως ξηρής κόνεως τιοτροπίου, άμεσα πληρωθείσας και σφραγισθείσας σε ένα δοχείο που έχει δημιουργηθεί ώστε να δρα ως ξηρός φραγμός υψηλής στεγανότητας για να αποτρέψει την παγίδευση και την είσοδο υγρασίας στην κόνη τιοτροπίου. Η δόση του τιοτροπίου είναι επιπλέον προσαρμοσμένη για εισπνοή και το δοχείο είναι τόσο στεγανό που η δραστικότητα της δόσεως όταν διανέμεται είναι ανεπηρέαστη από την υγρασία. Σε μία περαιτέρω όψη της εφευρέσεως απεικονίζεται ένα είδος εισπνευστήρα, που μπορεί να δεχθεί τουλάχιστον ένα σφραγισμένο, υδατοστεγές δοχείο μίας δόσεως τιοτροπίου, για τη διανομή της δόσεως με μία σταθερή δόση λεπτοδιαμερισμένων σωματιδίων, στο διάστημα της αναμενόμενης ημίσειας ζωής του προϊόντος.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0303269A SE0303269L (sv) | 2003-12-03 | 2003-12-03 | Medicinsk produkt |
EP04801707A EP1706099B1 (en) | 2003-12-03 | 2004-12-02 | A medical product comprising tiotropium in a moisture-proof container |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1111735T1 true CY1111735T1 (el) | 2015-10-07 |
Family
ID=29778162
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20111100727T CY1111735T1 (el) | 2003-12-03 | 2011-07-22 | Ιατρικο προϊον περιλαμβανον τιοτροπιο σε ενα υδατοστεγες δοχειο |
Country Status (25)
Country | Link |
---|---|
US (4) | US20050124644A1 (el) |
EP (1) | EP1706099B1 (el) |
JP (1) | JP2007513152A (el) |
KR (1) | KR101124071B1 (el) |
CN (2) | CN1913872B (el) |
AT (1) | ATE507821T1 (el) |
AU (1) | AU2004294886B2 (el) |
BR (1) | BRPI0417155A (el) |
CA (1) | CA2547781A1 (el) |
CY (1) | CY1111735T1 (el) |
DE (1) | DE602004032575D1 (el) |
DK (1) | DK1706099T3 (el) |
ES (1) | ES2362750T3 (el) |
HK (1) | HK1100643A1 (el) |
IL (1) | IL175887A (el) |
MX (1) | MXPA06006238A (el) |
NZ (1) | NZ547905A (el) |
PL (1) | PL1706099T3 (el) |
PT (1) | PT1706099E (el) |
RU (1) | RU2369385C2 (el) |
SE (1) | SE0303269L (el) |
SG (1) | SG148206A1 (el) |
SI (1) | SI1706099T1 (el) |
WO (1) | WO2005053644A1 (el) |
ZA (4) | ZA200604618B (el) |
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AU2004294889B2 (en) * | 2003-12-03 | 2010-08-26 | Boehringer Ingelheim International Gmbh | Medical product containing tiotropium |
SE0303270L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | Metod för administration av tiotropium |
SE0303569L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | DPI för avlämning av fuktkänsliga medikament |
SE0303571D0 (sv) * | 2003-12-03 | 2003-12-22 | Microdrug Ag | Medical product for moisture-sensitive medicaments |
SE0303570L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | Fukt-känslig medicinsk produkt |
SE0303269L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | Medicinsk produkt |
AU2004294890B2 (en) * | 2003-12-03 | 2010-08-26 | Boehringer Ingelheim International Gmbh | Pre-metered dry powder inhaler for moisture-sensitive medicaments |
RU2372105C2 (ru) | 2004-02-24 | 2009-11-10 | Майкродоуз Текнолоджиз, Инк. | Ингалятор с направленным датчиком потока |
CA2575692C (en) | 2004-08-20 | 2014-10-14 | Mannkind Corporation | Catalysis of diketopiperazine synthesis |
KR20130066695A (ko) | 2004-08-23 | 2013-06-20 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
TWI274641B (en) * | 2005-08-30 | 2007-03-01 | Rexon Ind Corp Ltd | Cutting machine |
CN104324362B (zh) | 2005-09-14 | 2018-04-24 | 曼金德公司 | 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法 |
MX2008010721A (es) | 2006-02-22 | 2008-09-01 | Mannkind Corp | Un metodo para mejorar las propiedades farmaceuticas de microparticulas que contienen dicetopiperazina y un agente activo. |
US9119777B2 (en) | 2008-05-30 | 2015-09-01 | Microdose Therapeutx, Inc. | Methods and compositions for administration of oxybutynin |
US8415390B2 (en) | 2008-05-30 | 2013-04-09 | Microdose Therapeutx, Inc. | Methods and compositions for administration of oxybutynin |
US8439033B2 (en) | 2007-10-09 | 2013-05-14 | Microdose Therapeutx, Inc. | Inhalation device |
US8371294B2 (en) | 2008-02-29 | 2013-02-12 | Microdose Therapeutx, Inc. | Method and apparatus for driving a transducer of an inhalation device |
US8424518B2 (en) | 2008-06-13 | 2013-04-23 | Mannkind Corporation | Dry powder inhaler and system for drug delivery |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
EP2609954B1 (en) | 2008-06-20 | 2021-12-29 | MannKind Corporation | An interactive apparatus for real-time profiling of inhalation efforts |
TWI494123B (zh) | 2008-08-11 | 2015-08-01 | Mannkind Corp | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
ES2739352T3 (es) | 2009-02-26 | 2020-01-30 | Glaxo Group Ltd | Formulaciones farmacéuticas que comprenden 4-{(1R)-2-[(6-{2-[(2,6-diclorobencil)oxi]etoxi}hexil)amino]-1-hidroxietil}-2-(hidroximetil)fenol |
JP5667095B2 (ja) | 2009-03-11 | 2015-02-12 | マンカインド コーポレイション | 吸入器の抵抗を測定するための装置、システムおよび方法 |
US8985101B2 (en) | 2009-05-21 | 2015-03-24 | Microdose Therapeutx, Inc. | Method and device for clamping a blister within a dry powder inhaler |
CA2762819C (en) | 2009-05-21 | 2016-12-20 | Microdose Therapeutx, Inc. | Rotary cassette system for dry powder inhaler |
KR20180036807A (ko) | 2009-06-12 | 2018-04-09 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
WO2011056889A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
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SE0303571D0 (sv) * | 2003-12-03 | 2003-12-22 | Microdrug Ag | Medical product for moisture-sensitive medicaments |
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SE0303269L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | Medicinsk produkt |
SE0303569L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | DPI för avlämning av fuktkänsliga medikament |
SE0303570L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | Fukt-känslig medicinsk produkt |
-
2003
- 2003-12-03 SE SE0303269A patent/SE0303269L/sv unknown
- 2003-12-08 US US10/728,986 patent/US20050124644A1/en not_active Abandoned
-
2004
- 2004-12-02 NZ NZ547905A patent/NZ547905A/en unknown
- 2004-12-02 EP EP04801707A patent/EP1706099B1/en not_active Revoked
- 2004-12-02 BR BRPI0417155-1A patent/BRPI0417155A/pt not_active Application Discontinuation
- 2004-12-02 SG SG200808774-4A patent/SG148206A1/en unknown
- 2004-12-02 RU RU2006122849/15A patent/RU2369385C2/ru active
- 2004-12-02 AT AT04801707T patent/ATE507821T1/de active
- 2004-12-02 JP JP2006542535A patent/JP2007513152A/ja active Pending
- 2004-12-02 KR KR1020067011729A patent/KR101124071B1/ko active IP Right Grant
- 2004-12-02 CA CA002547781A patent/CA2547781A1/en not_active Abandoned
- 2004-12-02 ES ES04801707T patent/ES2362750T3/es active Active
- 2004-12-02 AU AU2004294886A patent/AU2004294886B2/en active Active
- 2004-12-02 DE DE602004032575T patent/DE602004032575D1/de active Active
- 2004-12-02 ZA ZA200604618A patent/ZA200604618B/xx unknown
- 2004-12-02 SI SI200431694T patent/SI1706099T1/sl unknown
- 2004-12-02 CN CN2004800412129A patent/CN1913872B/zh active Active
- 2004-12-02 ZA ZA200605380A patent/ZA200605380B/en unknown
- 2004-12-02 ZA ZA200605379A patent/ZA200605379B/en unknown
- 2004-12-02 WO PCT/SE2004/001790 patent/WO2005053644A1/en active Application Filing
- 2004-12-02 PT PT04801707T patent/PT1706099E/pt unknown
- 2004-12-02 CN CN2004800413545A patent/CN1913873B/zh active Active
- 2004-12-02 ZA ZA200604616A patent/ZA200604616B/xx unknown
- 2004-12-02 PL PL04801707T patent/PL1706099T3/pl unknown
- 2004-12-02 MX MXPA06006238A patent/MXPA06006238A/es active IP Right Grant
- 2004-12-02 DK DK04801707.3T patent/DK1706099T3/da active
-
2006
- 2006-05-24 IL IL175887A patent/IL175887A/en active IP Right Grant
- 2006-06-08 US US11/448,773 patent/US20060257327A1/en not_active Abandoned
-
2007
- 2007-08-03 HK HK07108468.9A patent/HK1100643A1/xx unknown
-
2008
- 2008-10-21 US US12/255,086 patent/US20090041682A1/en not_active Abandoned
-
2009
- 2009-04-03 US US12/417,814 patent/US20090192185A1/en not_active Abandoned
-
2011
- 2011-07-22 CY CY20111100727T patent/CY1111735T1/el unknown
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