CY1111318T1 - Διαδερματικη φαρμακοτεχνικη μορφη στεροειδους - Google Patents

Διαδερματικη φαρμακοτεχνικη μορφη στεροειδους

Info

Publication number
CY1111318T1
CY1111318T1 CY20101101106T CY101101106T CY1111318T1 CY 1111318 T1 CY1111318 T1 CY 1111318T1 CY 20101101106 T CY20101101106 T CY 20101101106T CY 101101106 T CY101101106 T CY 101101106T CY 1111318 T1 CY1111318 T1 CY 1111318T1
Authority
CY
Cyprus
Prior art keywords
sup
group
weight
pharmaceutical form
acrylate
Prior art date
Application number
CY20101101106T
Other languages
English (en)
Inventor
James Robert Murray
Fumio Kamiyama
Ernst Wülfert
Original Assignee
Hunter-Fleming Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hunter-Fleming Limited filed Critical Hunter-Fleming Limited
Publication of CY1111318T1 publication Critical patent/CY1111318T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Ενώσεις τύπου (I) (όπου τα R1, R2, R3 και R4 είναι τα ίδια ή διαφορετικά το ένα από το άλλο και το καθένα αντιπροσωπεύει μια όξο ομάδα, υδρόξυ ομάδα, μερκάπτο ομάδα, άτομο υδρογόνου, άτομο αλογόνου, αλκόξυ ομάδα ή αρυλόξυ ομάδα και η στικτή γραμμή υποδεικνύει ότι μπορεί να υπάρχει απλός ή διπλός δεσμός μεταξύ ενός από τα αντίστοιχα ζεύγη ατόμων άνθρακα) και εστέρες αυτών, μπορεί να χορηγούνται με διαδερματική χορήγηση. Είναι ιδιαιτέρως αποτελεσματικές όταν εφαρμόζονται ως επίθεμα, κατά προτίμηση με συγκολλητικό που περιλαμβάνει συμπολυμερές από 40 έως 60% κατά βάρος ακρυλικό μεθοξυαιθυλαιθέρα, από 30 έως 40% κατά βάρος ακρυλικό λαουρύλ εστέρα ή μεθακρυλικό λαουρύλ εστέρα και από 10 έως 25% κατά βάρος πολικό μονομερές.
CY20101101106T 2004-04-28 2010-12-01 Διαδερματικη φαρμακοτεχνικη μορφη στεροειδους CY1111318T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0409498.3A GB0409498D0 (en) 2004-04-28 2004-04-28 Transdermal steroid formulation
EP05738733A EP1748779B1 (en) 2004-04-28 2005-04-28 Transdermal steroid formulation

Publications (1)

Publication Number Publication Date
CY1111318T1 true CY1111318T1 (el) 2015-08-05

Family

ID=32408193

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101101106T CY1111318T1 (el) 2004-04-28 2010-12-01 Διαδερματικη φαρμακοτεχνικη μορφη στεροειδους

Country Status (25)

Country Link
US (1) US20070231373A1 (el)
EP (1) EP1748779B1 (el)
JP (1) JP4849478B2 (el)
KR (1) KR101139023B1 (el)
CN (1) CN1997375B (el)
AT (1) ATE480241T1 (el)
AU (1) AU2005237285B2 (el)
CA (1) CA2563830C (el)
CY (1) CY1111318T1 (el)
DE (1) DE602005023436D1 (el)
DK (1) DK1748779T3 (el)
ES (1) ES2352202T3 (el)
GB (1) GB0409498D0 (el)
HK (1) HK1096606A1 (el)
HR (1) HRP20100558T1 (el)
IL (1) IL178781A (el)
NO (1) NO337073B1 (el)
NZ (1) NZ550784A (el)
PL (1) PL1748779T3 (el)
PT (1) PT1748779E (el)
RU (1) RU2371183C2 (el)
SI (1) SI1748779T1 (el)
TW (1) TWI354557B (el)
WO (1) WO2005105104A1 (el)
ZA (1) ZA200608878B (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0523550D0 (en) * 2005-11-18 2005-12-28 Hunter Fleming Ltd Therapeutic uses of steroidal compounds
AU2007327011A1 (en) * 2006-11-30 2008-06-05 Hunter-Fleming Limited Modulation of prostaglandin/cyclooxygenase metabolic pathways

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU210549B (en) * 1988-10-27 1995-05-29 Schering Ag Process for producing transdermally applicable pharmaceutical composition containing gestodene
US4978532A (en) * 1989-08-11 1990-12-18 Pharmedic Co. Dosage form for administration of dehydroepiandrosterone
AU6657894A (en) * 1993-05-18 1994-12-12 Ltt Institute Co., Ltd. Osteogenesis promoter and osteoporosis remedy
US5460820B1 (en) * 1993-08-03 1999-08-03 Theratech Inc Method for providing testosterone and optionally estrogen replacement therapy to women
DE4405898A1 (de) * 1994-02-18 1995-08-24 Schering Ag Transdermale therapeutische Systeme enthaltend Sexualsteroide
WO1996036339A2 (en) * 1995-05-15 1996-11-21 Beth Israel Hospital Use of dihydrotestosterone compounds for treating male sexual dysfunction
US5783208A (en) * 1996-07-19 1998-07-21 Theratech, Inc. Transdermal drug delivery matrix for coadministering estradiol and another steroid
US20010023261A1 (en) * 1997-01-27 2001-09-20 Lg Chemical Limited. Novel composition for the transdermal administration of drugs
KR100215027B1 (ko) * 1997-01-27 1999-08-16 성재갑 스테로이드계 약물의 경피흡수투여용 조성물 및 이를 포함하는 경피흡수투여용 제형
DE19728517C2 (de) * 1997-07-04 1999-11-11 Sanol Arznei Schwarz Gmbh TTS zur Verabreichung von Sexualsteroidhormonen und Verfahren zu seiner Herstellung
US20020012694A1 (en) * 1997-09-17 2002-01-31 Alfred J. Moo-Young Transdermal administration of ment
US5869090A (en) * 1998-01-20 1999-02-09 Rosenbaum; Jerry Transdermal delivery of dehydroepiandrosterone
DE19827732A1 (de) * 1998-06-22 1999-12-23 Rottapharm Bv Transdermales System vom Matrix-Typ zur Abgabe von Wirkstoffen mit einer hohen Abgaberate von Steroid-Hormonen und die Verwendung eines derartigen Systems zur Hormonersatztherapie
GB2363984A (en) * 2000-06-29 2002-01-16 Hunter Fleming Ltd Protection against neuronal damage using 3-hydroxy-7 -hydroxy steroids and 3-oxo-7 -hydroxy steroids
GB2363983A (en) * 2000-06-29 2002-01-16 Hunter Fleming Ltd Protection against neuronal damage using 7-hydroxyepiandrosterone
ES2423899T3 (es) * 2000-08-30 2013-09-25 Unimed Pharmaceuticals, Llc Método para aumentar las concentraciones de testosterona y esteroides relacionados en las mujeres
FR2818148B1 (fr) * 2000-12-15 2005-06-24 Oreal Composition,notamment cosmetique, renfermant, la 7-hydroxy dhea et/ou la 7-ceto dhea et au moins un isoflavonoide
US6510801B2 (en) * 2001-06-01 2003-01-28 Hong Sin Tan Pallet for shrinkwrapped packaging of block rubber
GB2378898A (en) * 2001-08-14 2003-02-26 Hunter Fleming Ltd Prophylactic and therapeutic use of hydroxysteroids
EP1607104B1 (en) * 2003-03-27 2015-12-09 COSMED Pharmaceutical Co. Ltd. Pressure-sensitive adhesive for percutaneous absorption, pressure-sensitive adhesive composition for percutaneous absorption, and medicinal preparation for percutaneous absorption

Also Published As

Publication number Publication date
RU2371183C2 (ru) 2009-10-27
RU2006141830A (ru) 2008-06-10
CA2563830A1 (en) 2005-11-10
NZ550784A (en) 2010-03-26
HK1096606A1 (en) 2007-06-08
ZA200608878B (en) 2008-07-30
JP2007534734A (ja) 2007-11-29
KR20070004995A (ko) 2007-01-09
PL1748779T3 (pl) 2011-03-31
NO337073B1 (no) 2016-01-18
DK1748779T3 (da) 2010-12-13
AU2005237285A1 (en) 2005-11-10
AU2005237285B2 (en) 2010-10-14
CN1997375B (zh) 2010-09-22
SI1748779T1 (sl) 2011-01-31
IL178781A0 (en) 2007-05-15
CN1997375A (zh) 2007-07-11
ES2352202T3 (es) 2011-02-16
GB0409498D0 (en) 2004-06-02
CA2563830C (en) 2013-01-15
ATE480241T1 (de) 2010-09-15
EP1748779B1 (en) 2010-09-08
IL178781A (en) 2013-10-31
HRP20100558T1 (hr) 2010-11-30
WO2005105104A1 (en) 2005-11-10
PT1748779E (pt) 2010-11-02
TWI354557B (en) 2011-12-21
EP1748779A1 (en) 2007-02-07
JP4849478B2 (ja) 2012-01-11
US20070231373A1 (en) 2007-10-04
DE602005023436D1 (de) 2010-10-21
KR101139023B1 (ko) 2012-04-26
NO20065440L (no) 2006-11-27
TW200538133A (en) 2005-12-01

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