CY1111042T1 - Μεθοδος απομονωσης βλαστικων κυτταρων - Google Patents

Μεθοδος απομονωσης βλαστικων κυτταρων

Info

Publication number
CY1111042T1
CY1111042T1 CY20091100136T CY091100136T CY1111042T1 CY 1111042 T1 CY1111042 T1 CY 1111042T1 CY 20091100136 T CY20091100136 T CY 20091100136T CY 091100136 T CY091100136 T CY 091100136T CY 1111042 T1 CY1111042 T1 CY 1111042T1
Authority
CY
Cyprus
Prior art keywords
stem cells
insulation
present
cell populations
isolated according
Prior art date
Application number
CY20091100136T
Other languages
English (en)
Inventor
Clayton A Smith
Michael Colvin
Robert W Storms
Susan M Ludeman
Original Assignee
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duke University filed Critical Duke University
Publication of CY1111042T1 publication Critical patent/CY1111042T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Molecular Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

Η παρούσα εφεύρεση αφορά, γενικά, βλαστοκύτταρα και συγκεκριμένα μέθοδο απομόνωσης βλαστικών κυττάρων και αντιδραστήρια κατάλληλα για χρήση σε μία τέτοια μέθοδο. Η εφεύρεση περαιτέρω αφορά πληθυσμούς βλαστικού κυττάρου, απομονώσιμους σύμφωνα με την παρούσα μέθοδο.
CY20091100136T 1998-12-07 2009-02-05 Μεθοδος απομονωσης βλαστικων κυτταρων CY1111042T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11119598P 1998-12-07 1998-12-07
EP99965994A EP1137798B1 (en) 1998-12-07 1999-12-07 A method of isolating stem cells

Publications (1)

Publication Number Publication Date
CY1111042T1 true CY1111042T1 (el) 2015-06-11

Family

ID=22337091

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20091100136T CY1111042T1 (el) 1998-12-07 2009-02-05 Μεθοδος απομονωσης βλαστικων κυτταρων
CY20101100522T CY1111098T1 (el) 1998-12-07 2010-06-11 Bodipy διαιθυλοακεταλη αμινοακεταλδεϋδης

Family Applications After (1)

Application Number Title Priority Date Filing Date
CY20101100522T CY1111098T1 (el) 1998-12-07 2010-06-11 Bodipy διαιθυλοακεταλη αμινοακεταλδεϋδης

Country Status (12)

Country Link
US (3) US6627759B1 (el)
EP (2) EP1975243B1 (el)
JP (1) JP4498614B2 (el)
AT (2) ATE414783T1 (el)
AU (1) AU774566B2 (el)
CA (1) CA2353701C (el)
CY (2) CY1111042T1 (el)
DE (2) DE69939945D1 (el)
DK (2) DK1975243T3 (el)
ES (2) ES2317707T3 (el)
PT (2) PT1137798E (el)
WO (1) WO2000034507A1 (el)

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CN100362095C (zh) 2001-03-27 2008-01-16 沃泰克斯药物股份有限公司 用于hcv感染的组合物和方法
US20030049836A1 (en) * 2001-08-15 2003-03-13 Phi-Wilson Janette T. Cell separation system
WO2004005496A1 (ja) * 2002-07-05 2004-01-15 Kirin Beer Kabushiki Kaisha 臍帯血、骨髄、末梢血等に含まれる新規な未分化幹細胞集団
AU2004316477B2 (en) * 2004-02-11 2010-10-07 Aldagen, Inc. Stem cell populations and methods of use
US7622108B2 (en) * 2004-04-23 2009-11-24 Bioe, Inc. Multi-lineage progenitor cells
US7670596B2 (en) * 2004-04-23 2010-03-02 Bioe, Inc. Multi-lineage progenitor cells
WO2005107807A2 (en) * 2004-05-06 2005-11-17 University Of South Florida Cerebral intraventricular transplantation as method of treating amyotrophic lateral sclerosis
JP2006349658A (ja) * 2005-02-21 2006-12-28 Hisamitsu Pharmaceut Co Inc 神経系癌幹細胞の検出試薬、神経系癌幹細胞を分離する方法、神経系癌幹細胞、及び神経芽腫の予後診断薬。
TW200726474A (en) * 2005-07-15 2007-07-16 Cognate Therapeutics Inc The immunophenotype and immunogenicity of human adipose derived cells
US20100034778A1 (en) * 2005-09-14 2010-02-11 Duke University Stem cells
WO2007033330A2 (en) * 2005-09-14 2007-03-22 Duke University Stem cells
CA2631760A1 (en) * 2005-12-02 2007-06-07 Robert A. Brodsky Use of high-dose oxazaphosphorine drugs for treating immune disorders
EP2019858B1 (en) * 2006-04-17 2012-06-13 BioE LLC Differentiation of multi-lineage progenitor cells to respiratory epithelial cells
JP2009537137A (ja) * 2006-05-17 2009-10-29 コグネート セラピューティクス，インコーポレーテッド 脂肪吸引後の脂肪吸引物からの造血幹細胞の単離および精製
WO2008034071A2 (en) * 2006-09-15 2008-03-20 The Johns Hopkins University Method of identifying patients suitable for high-dose cyclophosphamide treatment
WO2008034074A2 (en) 2006-09-15 2008-03-20 The Johns Hopkins University Cyclosphosphamide in combination with anti-idiotypic vaccines
WO2008034076A2 (en) 2006-09-15 2008-03-20 The Johns Hopkins University Cyclophosphamide in combination with immune therapeutics
US20080187938A1 (en) * 2006-09-22 2008-08-07 The Regents Of The University Of Michigan ALDH1 As A Cancer Stem Cell Marker
US20080226608A1 (en) * 2007-01-15 2008-09-18 Washington University Methods of Isolating and Using Enriched Subpopulations of Bone Marrow Progenitors for the Treatment of Diabetes
EP2192908A4 (en) * 2007-07-25 2010-09-01 Bioe Inc DIFFERENTIATION OF PRECURSOR CELLS OF MULTIPLE ABSTRACTS AGAINST CHONDROCYTES
US9026372B2 (en) * 2007-11-21 2015-05-05 Accentia Biopharmaceuticals, Inc. Methods for providing a system of care for a high-dose oxazaphosphorine drug regimen
WO2009067699A2 (en) * 2007-11-21 2009-05-28 Accentia Biopharmaceuticals, Inc. Methods for providing a system of care for an oxazaphosphorine drug regimen
EP2294187A2 (en) * 2008-05-21 2011-03-16 BioE LLC Differentiation of multi-lineage progenitor cells to pancreatic cells
US20110312001A1 (en) 2010-06-15 2011-12-22 Emile Nuwaysir Compendium of ready-built stem cell models for interrogation of biological response
CA2804595C (en) 2010-07-07 2018-11-13 Cellular Dynamics International, Inc. Endothelial cell production by programming
EP2643328B1 (en) 2010-11-24 2015-07-01 National University of Singapore Bodipy structure fluorescence dye for neural stem cell probe
JP6005666B2 (ja) 2011-02-08 2016-10-12 セルラー ダイナミクス インターナショナル， インコーポレイテッド プログラミングによる造血前駆細胞の生産
CN103193841A (zh) 2012-01-06 2013-07-10 维瑞斯特姆有限公司 治疗性化合物及相关使用方法
US8715529B1 (en) 2012-01-23 2014-05-06 Arrowhead Center, Inc. Synthesis and applications of triazaborolopyridinium compounds and substituted triazaborolopyridinium compounds and methods of use
US10156521B2 (en) 2013-02-21 2018-12-18 The Johns Hopkins University Red fluorescent aldehyde dehydrogenase (ALDH) substrate
JP2016508726A (ja) 2013-02-22 2016-03-24 セルラー ダイナミクス インターナショナル， インコーポレイテッド 組み合わせた遺伝的および化学的操作によるフォワードプログラミングを介した肝細胞の産生
WO2014145493A1 (en) * 2013-03-15 2014-09-18 The Johns Hopkins University Radioactive substrates for aldehyde dehydrogenase
AU2014248167B2 (en) 2013-04-03 2019-10-10 FUJIFILM Cellular Dynamics, Inc. Methods and compositions for culturing endoderm progenitor cells in suspension
WO2015164228A1 (en) 2014-04-21 2015-10-29 Cellular Dynamics International, Inc. Hepatocyte production via forward programming by combined genetic and chemical engineering
FR3054564B1 (fr) * 2016-07-28 2018-08-31 Advanced Biodesign Substrat specifique d'une isoenzyme de l'aldh
CN109916866B (zh) * 2019-03-04 2021-06-29 三峡大学 一种七元氟硼荧光染料的新用途
CN111172109A (zh) * 2019-12-20 2020-05-19 广州海润康华生物科技有限公司 一种免疫细胞培养方法及其应用
CA3216719A1 (en) 2021-05-03 2022-11-10 Astellas Institute For Regenerative Medicine Methods of generating mature corneal endothelial cells
BR112023022181A2 (pt) 2021-05-07 2024-02-06 Astellas Inst For Regenerative Medicine Métodos de geração de hepatócitos maduros
TW202417614A (zh) 2022-08-23 2024-05-01 安斯泰來再生醫藥協會 用於治療眼部病症的感光救援細胞（prc）組成物及方法

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US4774339A (en) * 1987-08-10 1988-09-27 Molecular Probes, Inc. Chemically reactive dipyrrometheneboron difluoride dyes
US5061620A (en) * 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell
US5274113A (en) * 1991-11-01 1993-12-28 Molecular Probes, Inc. Long wavelength chemically reactive dipyrrometheneboron difluoride dyes and conjugates
US5244636A (en) * 1991-01-25 1993-09-14 Trustees Of Tufts College Imaging fiber optic array sensors, apparatus, and methods for concurrently detecting multiple analytes of interest in a fluid sample
US5876956A (en) * 1995-05-15 1999-03-02 Johns Hopkins University School Of Medicine Methods for identification or purification of cells containing an enzymatic intracellular marker

Also Published As

Publication number Publication date
EP1137798A1 (en) 2001-10-04
AU774566B2 (en) 2004-07-01
ES2317707T3 (es) 2009-04-16
EP1975243A1 (en) 2008-10-01
CY1111098T1 (el) 2015-06-11
DK1975243T3 (da) 2010-06-28
DE69939945D1 (de) 2009-01-02
DK1137798T3 (da) 2009-04-14
WO2000034507A1 (en) 2000-06-15
ES2343222T3 (es) 2010-07-26
US6991897B2 (en) 2006-01-31
AU2165200A (en) 2000-06-26
JP4498614B2 (ja) 2010-07-07
DE69942185D1 (de) 2010-05-06
CA2353701C (en) 2014-06-03
US6627759B1 (en) 2003-09-30
PT1137798E (pt) 2009-02-20
PT1975243E (pt) 2010-06-24
EP1137798A4 (en) 2003-06-25
EP1137798B1 (en) 2008-11-19
JP2002531139A (ja) 2002-09-24
ATE462014T1 (de) 2010-04-15
ATE414783T1 (de) 2008-12-15
CA2353701A1 (en) 2000-06-15
US20060051833A1 (en) 2006-03-09
US7754480B2 (en) 2010-07-13
EP1975243B1 (en) 2010-03-24
US20040023318A1 (en) 2004-02-05

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