ATE414783T1 - Verfahren zur isolierung von stammzellen - Google Patents

Verfahren zur isolierung von stammzellen

Info

Publication number
ATE414783T1
ATE414783T1 AT99965994T AT99965994T ATE414783T1 AT E414783 T1 ATE414783 T1 AT E414783T1 AT 99965994 T AT99965994 T AT 99965994T AT 99965994 T AT99965994 T AT 99965994T AT E414783 T1 ATE414783 T1 AT E414783T1
Authority
AT
Austria
Prior art keywords
stem cells
isolation
present
relates
isolatable
Prior art date
Application number
AT99965994T
Other languages
English (en)
Inventor
Clayton A Smith
Michael Colvin
Robert Storms
Susan Ludeman
Original Assignee
Univ Duke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Duke filed Critical Univ Duke
Application granted granted Critical
Publication of ATE414783T1 publication Critical patent/ATE414783T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT99965994T 1998-12-07 1999-12-07 Verfahren zur isolierung von stammzellen ATE414783T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11119598P 1998-12-07 1998-12-07

Publications (1)

Publication Number Publication Date
ATE414783T1 true ATE414783T1 (de) 2008-12-15

Family

ID=22337091

Family Applications (2)

Application Number Title Priority Date Filing Date
AT08010501T ATE462014T1 (de) 1998-12-07 1999-12-07 Bodipy aminoacetaldehyd diethyl acetal
AT99965994T ATE414783T1 (de) 1998-12-07 1999-12-07 Verfahren zur isolierung von stammzellen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT08010501T ATE462014T1 (de) 1998-12-07 1999-12-07 Bodipy aminoacetaldehyd diethyl acetal

Country Status (12)

Country Link
US (3) US6627759B1 (de)
EP (2) EP1137798B1 (de)
JP (1) JP4498614B2 (de)
AT (2) ATE462014T1 (de)
AU (1) AU774566B2 (de)
CA (1) CA2353701C (de)
CY (2) CY1111042T1 (de)
DE (2) DE69942185D1 (de)
DK (2) DK1137798T3 (de)
ES (2) ES2317707T3 (de)
PT (2) PT1975243E (de)
WO (1) WO2000034507A1 (de)

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JP4499990B2 (ja) 2001-03-27 2010-07-14 バーテックス ファーマシューティカルズ インコーポレイテッド Ｈｃｖ感染に有用な組成物および方法
US20030049836A1 (en) * 2001-08-15 2003-03-13 Phi-Wilson Janette T. Cell separation system
WO2004005496A1 (ja) * 2002-07-05 2004-01-15 Kirin Beer Kabushiki Kaisha 臍帯血、骨髄、末梢血等に含まれる新規な未分化幹細胞集団
CA2556018A1 (en) * 2004-02-11 2005-09-09 Aldagen, Inc. Stem cell populations and methods of use
CA2563518C (en) * 2004-04-23 2014-09-02 Bioe, Inc. Multi-lineage progenitor cells
US7622108B2 (en) * 2004-04-23 2009-11-24 Bioe, Inc. Multi-lineage progenitor cells
US8765119B2 (en) * 2004-05-06 2014-07-01 University Of South Florida Treating amyotrophic lateral sclerosis (ALS)with isolated aldehyde dehydrogenase-positive umbilical cord blood cells
JP2006349658A (ja) * 2005-02-21 2006-12-28 Hisamitsu Pharmaceut Co Inc 神経系癌幹細胞の検出試薬、神経系癌幹細胞を分離する方法、神経系癌幹細胞、及び神経芽腫の予後診断薬。
TW200726474A (en) * 2005-07-15 2007-07-16 Cognate Therapeutics Inc The immunophenotype and immunogenicity of human adipose derived cells
WO2007033331A2 (en) * 2005-09-14 2007-03-22 Duke University Stem cells
US20090220462A1 (en) * 2005-09-14 2009-09-03 Duke University Stem cells
AU2006320162B2 (en) * 2005-12-02 2013-07-25 The Johns Hopkins University Use of high-dose oxazaphosphorine drugs for treating immune disorders
US7727763B2 (en) * 2006-04-17 2010-06-01 Bioe, Llc Differentiation of multi-lineage progenitor cells to respiratory epithelial cells
WO2007136424A2 (en) * 2006-05-17 2007-11-29 Cognate Therapeutics, Inc. Isolation and purification of hematopoietic stem cells from post-liposuction lipoaspirates
WO2008034074A2 (en) 2006-09-15 2008-03-20 The Johns Hopkins University Cyclosphosphamide in combination with anti-idiotypic vaccines
WO2008034076A2 (en) 2006-09-15 2008-03-20 The Johns Hopkins University Cyclophosphamide in combination with immune therapeutics
WO2008034071A2 (en) 2006-09-15 2008-03-20 The Johns Hopkins University Method of identifying patients suitable for high-dose cyclophosphamide treatment
US20080187938A1 (en) * 2006-09-22 2008-08-07 The Regents Of The University Of Michigan ALDH1 As A Cancer Stem Cell Marker
US20080226608A1 (en) * 2007-01-15 2008-09-18 Washington University Methods of Isolating and Using Enriched Subpopulations of Bone Marrow Progenitors for the Treatment of Diabetes
EP2192908A4 (de) * 2007-07-25 2010-09-01 Bioe Inc Differenzierung von vorläuferzellen mehrerer abstammung gegenüber chondrozyten
US9026372B2 (en) * 2007-11-21 2015-05-05 Accentia Biopharmaceuticals, Inc. Methods for providing a system of care for a high-dose oxazaphosphorine drug regimen
WO2009067690A2 (en) * 2007-11-21 2009-05-28 Accentia Biopharmaceuticals, Inc. Methods for safe and effective treatment using oxazaphosphorine drugs
CA2724839A1 (en) * 2008-05-21 2009-11-26 Bioe Llc Differentiation of multi-lineage progenitor cells to pancreatic cells
JP2013530699A (ja) 2010-06-15 2013-08-01 セルラー ダイナミクス インターナショナル， インコーポレイテッド 生物学的応答の調査のための既製の幹細胞モデルの概要
EP2591093B1 (de) 2010-07-07 2018-11-28 FUJIFILM Cellular Dynamics, Inc. Endothelzellenproduktion durch programmierung
SG190173A1 (en) 2010-11-24 2013-07-31 Univ Singapore Bodipy structure fluorescence dye for neural stem cell probe
WO2012109208A2 (en) 2011-02-08 2012-08-16 Cellular Dynamics International, Inc. Hematopoietic precursor cell production by programming
CN103193841A (zh) 2012-01-06 2013-07-10 维瑞斯特姆有限公司 治疗性化合物及相关使用方法
US8715529B1 (en) 2012-01-23 2014-05-06 Arrowhead Center, Inc. Synthesis and applications of triazaborolopyridinium compounds and substituted triazaborolopyridinium compounds and methods of use
US10156521B2 (en) 2013-02-21 2018-12-18 The Johns Hopkins University Red fluorescent aldehyde dehydrogenase (ALDH) substrate
EP2958992A1 (de) 2013-02-22 2015-12-30 Cellular Dynamics International, Inc. Hepatozytenproduktion über vorwärtsprogrammierung durch kombination aus gentechnik und chemotechnik
WO2014145493A1 (en) * 2013-03-15 2014-09-18 The Johns Hopkins University Radioactive substrates for aldehyde dehydrogenase
WO2014165663A1 (en) 2013-04-03 2014-10-09 Cellular Dynamics International, Inc. Methods and compositions for culturing endoderm progenitor cells in suspension
WO2015164228A1 (en) 2014-04-21 2015-10-29 Cellular Dynamics International, Inc. Hepatocyte production via forward programming by combined genetic and chemical engineering
FR3054564B1 (fr) * 2016-07-28 2018-08-31 Advanced Biodesign Substrat specifique d'une isoenzyme de l'aldh
CN109916866B (zh) * 2019-03-04 2021-06-29 三峡大学 一种七元氟硼荧光染料的新用途
CN111172109A (zh) * 2019-12-20 2020-05-19 广州海润康华生物科技有限公司 一种免疫细胞培养方法及其应用
MX2023013079A (es) 2021-05-03 2023-11-16 Astellas Inst For Regenerative Medicine Metodos de generacion de celulas maduras del endotelio corneal.
TW202309268A (zh) 2021-05-07 2023-03-01 安斯泰來再生醫藥協會 產生成熟肝細胞的方法
JP2025530638A (ja) 2022-08-23 2025-09-17 アステラス インスティテュート フォー リジェネレイティブ メディシン 光受容体レスキュー細胞（ｐｒｃ）組成物および眼障害の処置のための方法

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Publication number Priority date Publication date Assignee Title
US4774339A (en) * 1987-08-10 1988-09-27 Molecular Probes, Inc. Chemically reactive dipyrrometheneboron difluoride dyes
US5061620A (en) * 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell
US5274113A (en) * 1991-11-01 1993-12-28 Molecular Probes, Inc. Long wavelength chemically reactive dipyrrometheneboron difluoride dyes and conjugates
US5244636A (en) * 1991-01-25 1993-09-14 Trustees Of Tufts College Imaging fiber optic array sensors, apparatus, and methods for concurrently detecting multiple analytes of interest in a fluid sample
US5876956A (en) 1995-05-15 1999-03-02 Johns Hopkins University School Of Medicine Methods for identification or purification of cells containing an enzymatic intracellular marker

Also Published As

Publication number Publication date
ES2317707T3 (es) 2009-04-16
CA2353701C (en) 2014-06-03
EP1137798A1 (de) 2001-10-04
AU2165200A (en) 2000-06-26
PT1137798E (pt) 2009-02-20
US20060051833A1 (en) 2006-03-09
DE69942185D1 (de) 2010-05-06
CY1111042T1 (el) 2015-06-11
JP4498614B2 (ja) 2010-07-07
ES2343222T3 (es) 2010-07-26
CA2353701A1 (en) 2000-06-15
AU774566B2 (en) 2004-07-01
WO2000034507A1 (en) 2000-06-15
EP1137798B1 (de) 2008-11-19
DK1137798T3 (da) 2009-04-14
US6991897B2 (en) 2006-01-31
US6627759B1 (en) 2003-09-30
US7754480B2 (en) 2010-07-13
ATE462014T1 (de) 2010-04-15
DK1975243T3 (da) 2010-06-28
EP1137798A4 (de) 2003-06-25
EP1975243A1 (de) 2008-10-01
PT1975243E (pt) 2010-06-24
EP1975243B1 (de) 2010-03-24
US20040023318A1 (en) 2004-02-05
JP2002531139A (ja) 2002-09-24
DE69939945D1 (de) 2009-01-02
CY1111098T1 (el) 2015-06-11

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