ATE414783T1 - Verfahren zur isolierung von stammzellen - Google Patents

Verfahren zur isolierung von stammzellen

Info

Publication number
ATE414783T1
ATE414783T1 AT99965994T AT99965994T ATE414783T1 AT E414783 T1 ATE414783 T1 AT E414783T1 AT 99965994 T AT99965994 T AT 99965994T AT 99965994 T AT99965994 T AT 99965994T AT E414783 T1 ATE414783 T1 AT E414783T1
Authority
AT
Austria
Prior art keywords
stem cells
isolation
present
relates
isolatable
Prior art date
Application number
AT99965994T
Other languages
English (en)
Inventor
Clayton A Smith
Michael Colvin
Robert Storms
Susan Ludeman
Original Assignee
Univ Duke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Duke filed Critical Univ Duke
Application granted granted Critical
Publication of ATE414783T1 publication Critical patent/ATE414783T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems
AT99965994T 1998-12-07 1999-12-07 Verfahren zur isolierung von stammzellen ATE414783T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11119598P 1998-12-07 1998-12-07

Publications (1)

Publication Number Publication Date
ATE414783T1 true ATE414783T1 (de) 2008-12-15

Family

ID=22337091

Family Applications (2)

Application Number Title Priority Date Filing Date
AT08010501T ATE462014T1 (de) 1998-12-07 1999-12-07 Bodipy aminoacetaldehyd diethyl acetal
AT99965994T ATE414783T1 (de) 1998-12-07 1999-12-07 Verfahren zur isolierung von stammzellen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT08010501T ATE462014T1 (de) 1998-12-07 1999-12-07 Bodipy aminoacetaldehyd diethyl acetal

Country Status (12)

Country Link
US (3) US6627759B1 (de)
EP (2) EP1137798B1 (de)
JP (1) JP4498614B2 (de)
AT (2) ATE462014T1 (de)
AU (1) AU774566B2 (de)
CA (1) CA2353701C (de)
CY (2) CY1111042T1 (de)
DE (2) DE69942185D1 (de)
DK (2) DK1137798T3 (de)
ES (2) ES2317707T3 (de)
PT (2) PT1137798E (de)
WO (1) WO2000034507A1 (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4499990B2 (ja) * 2001-03-27 2010-07-14 バーテックス ファーマシューティカルズ インコーポレイテッド Ｈｃｖ感染に有用な組成物および方法
US20030049836A1 (en) * 2001-08-15 2003-03-13 Phi-Wilson Janette T. Cell separation system
AU2003281309A1 (en) * 2002-07-05 2004-01-23 Kirin Beer Kabushiki Kaisha Novel undifferentiated stem cells contained in cord blood, bone marrow, peripheral blood or the like
JP2007521831A (ja) 2004-02-11 2007-08-09 アルダジェン， インコーポレイテッド 幹細胞集団および使用方法
US7622108B2 (en) * 2004-04-23 2009-11-24 Bioe, Inc. Multi-lineage progenitor cells
US7670596B2 (en) * 2004-04-23 2010-03-02 Bioe, Inc. Multi-lineage progenitor cells
US8765119B2 (en) * 2004-05-06 2014-07-01 University Of South Florida Treating amyotrophic lateral sclerosis (ALS)with isolated aldehyde dehydrogenase-positive umbilical cord blood cells
JP2006349658A (ja) * 2005-02-21 2006-12-28 Hisamitsu Pharmaceut Co Inc 神経系癌幹細胞の検出試薬、神経系癌幹細胞を分離する方法、神経系癌幹細胞、及び神経芽腫の予後診断薬。
TW200726474A (en) * 2005-07-15 2007-07-16 Cognate Therapeutics Inc The immunophenotype and immunogenicity of human adipose derived cells
WO2007033331A2 (en) * 2005-09-14 2007-03-22 Duke University Stem cells
US20090220462A1 (en) * 2005-09-14 2009-09-03 Duke University Stem cells
AU2006320162B2 (en) * 2005-12-02 2013-07-25 The Johns Hopkins University Use of high-dose oxazaphosphorine drugs for treating immune disorders
EP2019858B1 (de) * 2006-04-17 2012-06-13 BioE LLC Differenzierung von vorläuferzellen mit mehreren abstammungslinien in respiratorischen epithelzellen
EP3001902A1 (de) * 2006-05-17 2016-04-06 Cognate Therapeutics, Inc. Isolierung und reinigung von hämatopoetischen stammzellen aus lipoaspiraten nach der liposuktion
WO2008034076A2 (en) 2006-09-15 2008-03-20 The Johns Hopkins University Cyclophosphamide in combination with immune therapeutics
WO2008034071A2 (en) 2006-09-15 2008-03-20 The Johns Hopkins University Method of identifying patients suitable for high-dose cyclophosphamide treatment
WO2008034074A2 (en) 2006-09-15 2008-03-20 The Johns Hopkins University Cyclosphosphamide in combination with anti-idiotypic vaccines
US20080187938A1 (en) * 2006-09-22 2008-08-07 The Regents Of The University Of Michigan ALDH1 As A Cancer Stem Cell Marker
US20080226608A1 (en) * 2007-01-15 2008-09-18 Washington University Methods of Isolating and Using Enriched Subpopulations of Bone Marrow Progenitors for the Treatment of Diabetes
CN101835479A (zh) * 2007-07-25 2010-09-15 佰欧益有限公司 多系祖细胞分化为软骨细胞
US9026372B2 (en) * 2007-11-21 2015-05-05 Accentia Biopharmaceuticals, Inc. Methods for providing a system of care for a high-dose oxazaphosphorine drug regimen
WO2009067690A2 (en) * 2007-11-21 2009-05-28 Accentia Biopharmaceuticals, Inc. Methods for safe and effective treatment using oxazaphosphorine drugs
WO2009143241A2 (en) * 2008-05-21 2009-11-26 Bioe, Inc. Differentiation of multi-lineage progenitor cells to pancreatic cells
CA2802087A1 (en) 2010-06-15 2011-12-22 Cellular Dynamics International, Inc. A compendium of ready-built stem cell models for interrogation of biological response
JP5897002B2 (ja) 2010-07-07 2016-04-13 セルラー ダイナミクス インターナショナル， インコーポレイテッド プログラミングによる内皮細胞の産生
WO2012071012A2 (en) 2010-11-24 2012-05-31 National University Of Singapore Bodipy structure fluorescence dye for neural stem cell probe
WO2012109208A2 (en) 2011-02-08 2012-08-16 Cellular Dynamics International, Inc. Hematopoietic precursor cell production by programming
CN103193841A (zh) 2012-01-06 2013-07-10 维瑞斯特姆有限公司 治疗性化合物及相关使用方法
US8715529B1 (en) 2012-01-23 2014-05-06 Arrowhead Center, Inc. Synthesis and applications of triazaborolopyridinium compounds and substituted triazaborolopyridinium compounds and methods of use
WO2014130834A1 (en) 2013-02-21 2014-08-28 The Johns Hopkins University Red fluorescent aldehyde dehydrogenase (aldh) substrate
CN105229144A (zh) 2013-02-22 2016-01-06 细胞动力学国际有限公司 通过组合的遗传工程和化学工程经由正向编程产生肝细胞
WO2014145493A1 (en) * 2013-03-15 2014-09-18 The Johns Hopkins University Radioactive substrates for aldehyde dehydrogenase
JP6602288B2 (ja) 2013-04-03 2019-11-06 フジフィルム セルラー ダイナミクス，インコーポレイテッド 浮遊液中で内胚葉前駆細胞を培養するための方法および組成物
WO2015164228A1 (en) 2014-04-21 2015-10-29 Cellular Dynamics International, Inc. Hepatocyte production via forward programming by combined genetic and chemical engineering
FR3054564B1 (fr) * 2016-07-28 2018-08-31 Advanced Biodesign Substrat specifique d'une isoenzyme de l'aldh
CN109916866B (zh) * 2019-03-04 2021-06-29 三峡大学 一种七元氟硼荧光染料的新用途
CN111172109A (zh) * 2019-12-20 2020-05-19 广州海润康华生物科技有限公司 一种免疫细胞培养方法及其应用
AU2022270611A1 (en) 2021-05-03 2023-10-12 Astellas Institute For Regenerative Medicine Methods of generating mature corneal endothelial cells
CN117716020A (zh) 2021-05-07 2024-03-15 安斯泰来再生医药协会 产生成熟肝细胞的方法
WO2024044134A1 (en) 2022-08-23 2024-02-29 Astellas Institute For Regenerative Medicine Photoreceptor rescue cell (prc) compositions and methods for treatment of ocular disorders

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4774339A (en) * 1987-08-10 1988-09-27 Molecular Probes, Inc. Chemically reactive dipyrrometheneboron difluoride dyes
US5061620A (en) * 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell
US5274113A (en) * 1991-11-01 1993-12-28 Molecular Probes, Inc. Long wavelength chemically reactive dipyrrometheneboron difluoride dyes and conjugates
US5244636A (en) * 1991-01-25 1993-09-14 Trustees Of Tufts College Imaging fiber optic array sensors, apparatus, and methods for concurrently detecting multiple analytes of interest in a fluid sample
US5876956A (en) 1995-05-15 1999-03-02 Johns Hopkins University School Of Medicine Methods for identification or purification of cells containing an enzymatic intracellular marker

Also Published As

Publication number Publication date
PT1137798E (pt) 2009-02-20
US20060051833A1 (en) 2006-03-09
DK1975243T3 (da) 2010-06-28
ATE462014T1 (de) 2010-04-15
CA2353701A1 (en) 2000-06-15
WO2000034507A1 (en) 2000-06-15
EP1975243B1 (de) 2010-03-24
US6627759B1 (en) 2003-09-30
AU2165200A (en) 2000-06-26
EP1137798A1 (de) 2001-10-04
EP1137798B1 (de) 2008-11-19
JP2002531139A (ja) 2002-09-24
US7754480B2 (en) 2010-07-13
DK1137798T3 (da) 2009-04-14
EP1975243A1 (de) 2008-10-01
ES2343222T3 (es) 2010-07-26
CA2353701C (en) 2014-06-03
CY1111042T1 (el) 2015-06-11
PT1975243E (pt) 2010-06-24
US6991897B2 (en) 2006-01-31
EP1137798A4 (de) 2003-06-25
ES2317707T3 (es) 2009-04-16
DE69942185D1 (de) 2010-05-06
AU774566B2 (en) 2004-07-01
US20040023318A1 (en) 2004-02-05
DE69939945D1 (de) 2009-01-02
JP4498614B2 (ja) 2010-07-07
CY1111098T1 (el) 2015-06-11

Similar Documents

Publication Publication Date Title
ATE414783T1 (de) Verfahren zur isolierung von stammzellen
EP0508985A4 (en) Method and kit for purifying nucleic acids
BR9805900B1 (pt) processo para integrar um fragmento de dna no genoma de uma célula de uma planta manocotiledÈnea.
DK0389063T4 (da) Fremgangsmåde til isolering af nukleinsyre
ATE227739T1 (de) Hybridprotein zur hemmung der mastzelldegranulation und dessen verwendung
IL160394A0 (en) Methods for identifying and isolating stem cells and methods utilizing said cells
DK0799058T3 (da) Forbedringer af eller med hensyn til endometriefunktion
WO2003080816A3 (en) Stem cell culture
DE69719497D1 (de) Verfahren zur proteinaufreinigung aus einer proteinhaltigen lösung
DK1900811T3 (da) Berigede cellepopulationer i centralnervesystemet
DE69501326T2 (de) Differentielle expansion von fötalen stamzellen im mütterlichen kreislauf zur verwendung in der pränatalen genetischen analyse
CA2199835A1 (en) Method for preparing nucleic acids for analysis and kits useful therefor
DE68917154T2 (de) C-terminus-amidierungsenzym-zusammensetzung, verfahren zur herstellung und verwendung.
ATE242756T1 (de) Verfahren zur isolierung von glykolen
ATE353338T1 (de) Synthetische biepitopische zusammensetzungen zur verwendung als kalibratoren bei der biologischen bestimmung von troponin i
WO2001036673A3 (de) Test von mikroorganismen
DE69941218D1 (de) Matrix für karbonat-brennstoffzellen und verfahren zur herstellung derselben
WO2001007649A3 (de) Verfahren zum nachweis von mikroorganismen
ATE522604T1 (de) Verfahren zur herstellung von proteinen durch elektropulsierung
ATE318919T1 (de) Verfahren zur herstellung von proteinen in transformierten hefezellen
ATE293987T1 (de) Methode zur mobilisierung hematopoietischer stammzellen
WO2004046359A3 (en) Method of controlling gene expression in plants or plant cells
ATE317446T1 (de) Verfahren zur selektion von transformierten zellen
WO2004099385A3 (en) Telomere elongation
DE60137773D1 (de) Verfahren zur identifizierung und/oder isolierung von stammzellen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1137798

Country of ref document: EP