CY1110921T1 - Υποδοχεας κυτοκινης zcytor19 - Google Patents
Υποδοχεας κυτοκινης zcytor19Info
- Publication number
- CY1110921T1 CY1110921T1 CY20101100038T CY101100038T CY1110921T1 CY 1110921 T1 CY1110921 T1 CY 1110921T1 CY 20101100038 T CY20101100038 T CY 20101100038T CY 101100038 T CY101100038 T CY 101100038T CY 1110921 T1 CY1110921 T1 CY 1110921T1
- Authority
- CY
- Cyprus
- Prior art keywords
- polypeptides
- methods
- vitro
- vivo
- zcytor19
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Neurology (AREA)
- Cell Biology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- AIDS & HIV (AREA)
Abstract
Παρουσιάζονται νέα πολυπεπτίδια, πολυνουκλεοτίδια που κωδικεύουν τα πολυπεπτίδια, και σχετιζόμενες συνθέσεις και μέθοδοι για zcytor19, ένα νέο υποδοχέα κυτοκίνης κατηγορίας II. Τα πολυπεπτίδια μπορούν να χρησιμοποιηθούν στο πλαίσιο μεθόδων ανίχνευσης συνδετών που διεγείρουν τον πολλαπλασιασμό και/ή ανάπτυξη αιμοποιητικών, λεμφικών και μυελοειδών κυττάρων in vitro και in vivo. Τα πολυπεπτίδια υποδοχέα δέσμευσης συνδέτη μπορούν επίσης να χρησιμοποιηθούν για τον αποκλεισμό της ενεργότητας συνδέτη in vitro και in vivo. Τα πολυνουκλεοτίδια που κωδικεύουν τον zcytor19 εντοπίζονται στο χρωμόσωμα 1p36.11, και μπορούν να χρησιμοποιηθούν για την ταυτοποίηση περιοχής του γονιδιώματος που συνδέεται με παθολογικές καταστάσεις στον άνθρωπο. Η παρούσα εφεύρεση επίσης περιλαμβάνει μεθόδους για την παραγωγή της πρωτεΐνης, χρήσεις αυτής και αντισώματα έναντι αυτής.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25356100P | 2000-11-28 | 2000-11-28 | |
US26721101P | 2001-02-07 | 2001-02-07 | |
EP01988203A EP1356046B1 (en) | 2000-11-28 | 2001-11-28 | Cytokine receptor zcytor19 |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1110921T1 true CY1110921T1 (el) | 2015-06-10 |
Family
ID=26943370
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20101100038T CY1110921T1 (el) | 2000-11-28 | 2010-01-14 | Υποδοχεας κυτοκινης zcytor19 |
Country Status (12)
Country | Link |
---|---|
US (10) | US20030027253A1 (el) |
EP (1) | EP1356046B1 (el) |
JP (1) | JP2004532611A (el) |
AT (1) | ATE445701T1 (el) |
AU (1) | AU2002241533A1 (el) |
CA (1) | CA2430485A1 (el) |
CY (1) | CY1110921T1 (el) |
DE (1) | DE60140213D1 (el) |
DK (1) | DK1356046T3 (el) |
ES (1) | ES2334888T3 (el) |
PT (1) | PT1356046E (el) |
WO (1) | WO2002044209A2 (el) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030027253A1 (en) | 2000-11-28 | 2003-02-06 | Presnell Scott R. | Cytokine receptor zcytor19 |
TW200300170A (en) * | 2001-11-09 | 2003-05-16 | Wyeth Corp | Type 2 cytokine receptor and nucleic acids encoding same |
US7033787B2 (en) * | 2001-12-21 | 2006-04-25 | Ludwig Institute For Cancer Research | Isolated cytokine receptor LICR-2 |
CN101676728A (zh) | 2002-04-19 | 2010-03-24 | 津莫吉尼蒂克斯公司 | 细胞因子受体 |
US20040170982A1 (en) * | 2003-02-14 | 2004-09-02 | Morris David W. | Novel therapeutic targets in cancer |
US20060246161A1 (en) * | 2003-02-21 | 2006-11-02 | Hongtao Xing | Method of making medicament for treating anemia |
EP1927600A1 (en) | 2003-08-07 | 2008-06-04 | Zymogenetics, Inc. | Homogeneous preparations of IL-28 and IL-29 |
US7381794B2 (en) | 2004-03-08 | 2008-06-03 | Zymogenetics, Inc. | Dimeric fusion proteins and materials and methods for producing them |
CA2574564C (en) | 2004-07-29 | 2013-04-16 | Zymogenetics, Inc. | Use of il-28 and il-29 to treat cancer and autoimmune disorders |
NZ565460A (en) | 2005-07-26 | 2011-06-30 | Bial Portela & Ca Sa | Nitrocatechol derivatives as COMT inhibitors |
EP1845097A1 (en) | 2006-04-10 | 2007-10-17 | Portela & Ca., S.A. | Oxadiazole derivatives as COMT inhibitors |
US8524746B2 (en) | 2007-01-31 | 2013-09-03 | Bial-Portela & Ca., S.A. | Dosage regimen for COMT inhibitors |
CA2704038A1 (en) * | 2007-10-31 | 2009-05-07 | The Scripps Research Institute | Combination therapy to treat persistent viral infections |
ES2730678T3 (es) | 2009-04-01 | 2019-11-12 | Bial Portela & Ca Sa | Formulaciones farmacéuticas que comprenden derivados de nitrocatecol y métodos para fabricarlas |
ES2915698T3 (es) * | 2009-04-01 | 2022-06-24 | Bial Portela & Ca Sa | Formulaciones farmacéuticas que comprenden derivados de nitrocatecol y métodos para preparar las mismas |
US20140045900A1 (en) | 2011-02-11 | 2014-02-13 | Bial-Portela & Ca, S.A. | Administration regime for nitrocatechols |
MX2013014773A (es) * | 2011-06-13 | 2014-01-20 | Merck Sharp & Dohme | Procedimiento de purificacion de formas nativas o mutantes de la toxina difterica. |
HUE047856T2 (hu) | 2011-12-13 | 2020-05-28 | Bial Portela & Ca Sa | Kémiai vegyület, amely köztitermékként használható katechol-O-metil-transzferáz inhibitor elõállításához |
NZ630888A (en) * | 2013-03-15 | 2017-06-30 | Abbvie Inc | Antibody drug conjugate (adc) purification |
WO2014182658A1 (en) * | 2013-05-06 | 2014-11-13 | Abbvie Inc. | Compositions for cell culture and methods of using the same |
WO2016033509A1 (en) * | 2014-08-29 | 2016-03-03 | The Regents Of The University Of Colorado, A Body Corporate | Aquaporin-4 antibodies and uses thereof for the treatment of neuromyelitis optica |
WO2016083863A1 (en) | 2014-11-28 | 2016-06-02 | Bial - Portela & Ca, S.A. | Medicaments for slowing parkinson's disease |
KR102466763B1 (ko) * | 2016-04-13 | 2022-11-11 | 오리맵스 리미티드 | 항- psma 항체 및 이의 용도 |
WO2023049774A1 (en) * | 2021-09-21 | 2023-03-30 | University Of Washington | Genetically encoded and exogenously triggered protein-protein ligation |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7625697B2 (en) * | 1994-06-17 | 2009-12-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for constructing subarrays and subarrays made thereby |
US5945511A (en) * | 1997-02-20 | 1999-08-31 | Zymogenetics, Inc. | Class II cytokine receptor |
US5965704A (en) * | 1997-08-05 | 1999-10-12 | Zymogenetics, Inc. | Class two cytokine receptor-11 |
AU6069300A (en) | 1999-07-02 | 2001-01-22 | Chiron Corporation | Novel human genes and gene expression products |
EP2298789B1 (en) * | 2000-09-08 | 2012-03-14 | Schering Corporation | Mammalian genes; related reagents and methods |
US20030027253A1 (en) * | 2000-11-28 | 2003-02-06 | Presnell Scott R. | Cytokine receptor zcytor19 |
CN101531715A (zh) * | 2001-04-20 | 2009-09-16 | 津莫吉尼蒂克斯公司 | 细胞因子蛋白质家族 |
JPWO2003031620A1 (ja) | 2001-10-02 | 2005-01-27 | 持田製薬株式会社 | 新規クラスiiサイトカイン受容体 |
TW200300170A (en) * | 2001-11-09 | 2003-05-16 | Wyeth Corp | Type 2 cytokine receptor and nucleic acids encoding same |
US7033787B2 (en) | 2001-12-21 | 2006-04-25 | Ludwig Institute For Cancer Research | Isolated cytokine receptor LICR-2 |
WO2003066002A2 (en) | 2002-02-08 | 2003-08-14 | University Of Medicine And Dentistry Of New Jersey | IFN-a/b-INDEPENDENT MECHANISM OF ANTIVIRAL PROTECTION |
CN101676728A (zh) * | 2002-04-19 | 2010-03-24 | 津莫吉尼蒂克斯公司 | 细胞因子受体 |
EP1575609A4 (en) | 2002-10-23 | 2010-12-15 | Zymogenetics L L C | METHOD FOR THE TREATMENT OF VIRUS INFECTIONS USING IL-28 AND IL-29 |
CA2516128A1 (en) | 2003-02-14 | 2004-09-02 | Sagres Discovery, Inc. | Therapeutic targets in cancer |
-
2001
- 2001-11-28 US US09/995,898 patent/US20030027253A1/en not_active Abandoned
- 2001-11-28 CA CA002430485A patent/CA2430485A1/en not_active Abandoned
- 2001-11-28 PT PT01988203T patent/PT1356046E/pt unknown
- 2001-11-28 ES ES01988203T patent/ES2334888T3/es not_active Expired - Lifetime
- 2001-11-28 WO PCT/US2001/044808 patent/WO2002044209A2/en active Application Filing
- 2001-11-28 AU AU2002241533A patent/AU2002241533A1/en not_active Abandoned
- 2001-11-28 AT AT01988203T patent/ATE445701T1/de active
- 2001-11-28 JP JP2002546578A patent/JP2004532611A/ja active Pending
- 2001-11-28 DK DK01988203.4T patent/DK1356046T3/da active
- 2001-11-28 DE DE60140213T patent/DE60140213D1/de not_active Expired - Lifetime
- 2001-11-28 EP EP01988203A patent/EP1356046B1/en not_active Expired - Lifetime
-
2005
- 2005-06-23 US US11/165,141 patent/US20050266485A1/en not_active Abandoned
-
2006
- 2006-10-05 US US11/539,072 patent/US7601809B2/en not_active Expired - Lifetime
- 2006-10-05 US US11/539,064 patent/US7608452B2/en not_active Expired - Lifetime
- 2006-10-05 US US11/539,079 patent/US20070048846A1/en not_active Abandoned
- 2006-10-06 US US11/539,283 patent/US20070048804A1/en not_active Abandoned
- 2006-10-06 US US11/539,286 patent/US7618791B2/en not_active Expired - Lifetime
-
2010
- 2010-01-14 CY CY20101100038T patent/CY1110921T1/el unknown
- 2010-04-08 US US12/756,985 patent/US20110091876A1/en not_active Abandoned
-
2011
- 2011-10-06 US US13/267,430 patent/US20120064571A1/en not_active Abandoned
-
2014
- 2014-04-02 US US14/243,708 patent/US20140248661A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ES2334888T3 (es) | 2010-03-17 |
EP1356046B1 (en) | 2009-10-14 |
US20030027253A1 (en) | 2003-02-06 |
DE60140213D1 (de) | 2009-11-26 |
EP1356046A2 (en) | 2003-10-29 |
US20070048846A1 (en) | 2007-03-01 |
WO2002044209A2 (en) | 2002-06-06 |
CA2430485A1 (en) | 2002-06-06 |
DK1356046T3 (da) | 2010-03-01 |
US7618791B2 (en) | 2009-11-17 |
US7601809B2 (en) | 2009-10-13 |
US20120064571A1 (en) | 2012-03-15 |
ATE445701T1 (de) | 2009-10-15 |
PT1356046E (pt) | 2010-03-09 |
US20070111942A1 (en) | 2007-05-17 |
US20140248661A1 (en) | 2014-09-04 |
US20110091876A1 (en) | 2011-04-21 |
US20070048804A1 (en) | 2007-03-01 |
AU2002241533A1 (en) | 2002-06-11 |
US20050266485A1 (en) | 2005-12-01 |
US20070048799A1 (en) | 2007-03-01 |
US7608452B2 (en) | 2009-10-27 |
JP2004532611A (ja) | 2004-10-28 |
WO2002044209A3 (en) | 2003-08-21 |
US20070117165A1 (en) | 2007-05-24 |
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