CY1109310T1 - Φαρμακοτεχνικες μορφες αγωνιστη οποιουχου με απελευθερωσιμο και απομονωμενο ανταγωνιστη - Google Patents
Φαρμακοτεχνικες μορφες αγωνιστη οποιουχου με απελευθερωσιμο και απομονωμενο ανταγωνιστηInfo
- Publication number
- CY1109310T1 CY1109310T1 CY091100871T CY091100871T CY1109310T1 CY 1109310 T1 CY1109310 T1 CY 1109310T1 CY 091100871 T CY091100871 T CY 091100871T CY 091100871 T CY091100871 T CY 091100871T CY 1109310 T1 CY1109310 T1 CY 1109310T1
- Authority
- CY
- Cyprus
- Prior art keywords
- liberable
- competitor
- competition
- insulated
- pharmaceutical forms
- Prior art date
Links
- 239000003401 opiate antagonist Substances 0.000 abstract 2
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000003402 opiate agonist Substances 0.000 abstract 1
- 239000006186 oral dosage form Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
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- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
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- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
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- A61K9/5005—Wall or coating material
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Abstract
Αποκαλύπτονται από του στόματος μορφές δοσολογίας που περιλαμβάνουν (i) θεραπευτικώς αποτελεσματική ποσότητα ενός αγωνιστή οπιούχου, (ii) ανταγωνιστή οπιούχου σε απελευθερώσιμη μορφή και (iii) απομονωμένο ανταγωνιστή οπιούχoυ ο οποίος δεν απελευθερώνεται όταν η μορφή δοσολογίας χορηγείται ανέπαφη και μέθοδοι αυτών.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31053601P | 2001-08-06 | 2001-08-06 | |
EP02756988A EP1414451B1 (en) | 2001-08-06 | 2002-08-06 | Opioid agonist formulations with releasable and sequestered antagonist |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1109310T1 true CY1109310T1 (el) | 2014-07-02 |
Family
ID=23202951
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY091100871T CY1109310T1 (el) | 2001-08-06 | 2009-08-12 | Φαρμακοτεχνικες μορφες αγωνιστη οποιουχου με απελευθερωσιμο και απομονωμενο ανταγωνιστη |
Country Status (28)
Country | Link |
---|---|
US (5) | US7914818B2 (el) |
EP (1) | EP1414451B1 (el) |
JP (2) | JP4504013B2 (el) |
KR (1) | KR20040029405A (el) |
AT (1) | ATE431738T1 (el) |
AU (1) | AU2002323032B2 (el) |
CA (1) | CA2457361C (el) |
CO (1) | CO5640086A2 (el) |
CY (1) | CY1109310T1 (el) |
DE (1) | DE60232417D1 (el) |
DK (1) | DK1414451T3 (el) |
ES (1) | ES2326794T3 (el) |
HR (1) | HRP20040125A2 (el) |
HU (1) | HUP0401191A3 (el) |
IL (1) | IL160222A0 (el) |
IS (1) | IS7142A (el) |
MA (1) | MA27265A1 (el) |
MX (1) | MXPA04001210A (el) |
NO (1) | NO20040968L (el) |
NZ (1) | NZ530971A (el) |
PL (1) | PL367427A1 (el) |
PT (1) | PT1414451E (el) |
RS (1) | RS12104A (el) |
RU (1) | RU2004106619A (el) |
SI (1) | SI1414451T1 (el) |
TN (1) | TNSN04025A1 (el) |
WO (1) | WO2003013525A1 (el) |
ZA (1) | ZA200400893B (el) |
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US5965161A (en) * | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
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AP1665A (en) | 2000-02-08 | 2006-09-22 | Euro Celtique Sa | Tamper-resistant oral opioid agonist formulations. |
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CN1525851A (zh) | 2001-05-11 | 2004-09-01 | ������ҩ������˾ | 抗滥用阿片样物质控释剂型 |
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US7157103B2 (en) | 2001-08-06 | 2007-01-02 | Euro-Celtique S.A. | Pharmaceutical formulation containing irritant |
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US7842307B2 (en) | 2001-08-06 | 2010-11-30 | Purdue Pharma L.P. | Pharmaceutical formulation containing opioid agonist, opioid antagonist and gelling agent |
WO2003026743A2 (en) * | 2001-09-26 | 2003-04-03 | Penwest Pharmaceuticals Company | Opioid formulations having reduced potential for abuse |
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US20050182056A9 (en) * | 2002-02-21 | 2005-08-18 | Seth Pawan | Modified release formulations of at least one form of tramadol |
AU2003220290B2 (en) * | 2002-03-14 | 2007-06-14 | Euro-Celtique S.A. | Naltrexone hydrochloride compositions |
CN100411611C (zh) | 2002-04-05 | 2008-08-20 | 欧洲凯尔蒂克公司 | 用于持续,不变且独立释放活性化合物的基质 |
CA2495564A1 (en) * | 2002-08-15 | 2005-01-27 | Euro-Celtique S.A. | Pharmaceutical compositions |
EP2422773A3 (en) | 2002-09-20 | 2012-04-18 | Alpharma, Inc. | Sequestering subunit and related compositions and methods |
GB0304726D0 (en) * | 2003-03-01 | 2003-04-02 | Ardana Bioscience Ltd | New Process |
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