CY1109022T1 - Psca: αντιγονο βλαστικου κυτταρου προστατη και χρησεις αυτου - Google Patents

Psca: αντιγονο βλαστικου κυτταρου προστατη και χρησεις αυτου

Info

Publication number
CY1109022T1
CY1109022T1 CY20091100459T CY091100459T CY1109022T1 CY 1109022 T1 CY1109022 T1 CY 1109022T1 CY 20091100459 T CY20091100459 T CY 20091100459T CY 091100459 T CY091100459 T CY 091100459T CY 1109022 T1 CY1109022 T1 CY 1109022T1
Authority
CY
Cyprus
Prior art keywords
psca
antigon
prostate
cell protection
androgen
Prior art date
Application number
CY20091100459T
Other languages
English (en)
Inventor
Robert Reiter
Owen Witte
Original Assignee
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/203,939 external-priority patent/US6258939B1/en
Priority claimed from US09/251,835 external-priority patent/US6261789B1/en
Application filed by The Regents Of The University Of California filed Critical The Regents Of The University Of California
Publication of CY1109022T1 publication Critical patent/CY1109022T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57434—Specifically defined cancers of prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Microbiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Hospice & Palliative Care (AREA)

Abstract

Η εφεύρεση παρέχει ένα νέο αντιγόνο επιφανείας κυττάρου προστάτη, που ορίζεται Αντιγόνο Βλαστικού Κυττάρου του Προστάτη (PSCA), το οποίο είναι ευρέως υπερεκφρασμένο κατά μήκος όλων των σταδίων του καρκίνου του προστάτη, συμπεριλαμβανομένης ανώτερης βαθμίδας προστατικής ενδοεπιθηλιακής νεοπλασίας (PIN),εξαρτώμενων από ανδρογόνο και ανεξάρτητων ανδρογόνου όγκων προστάτη. Επίσης παρέχει αντισώματα προς PSCA. Περαιτέρω, παρέχονται μέθοδοι ανίχνευσης/διάγνωσης και θεραπείας, καθώς επίσης διαγονιδιακό ζώο.
CY20091100459T 1998-12-02 2009-04-24 Psca: αντιγονο βλαστικου κυτταρου προστατη και χρησεις αυτου CY1109022T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US09/203,939 US6258939B1 (en) 1997-03-10 1998-12-02 PSCA antibodies and hybridomas producing them
US09/251,835 US6261789B1 (en) 1997-03-10 1999-02-17 Methods for detecting the presence of a PSCA protein using PSCA antibodies
US09/318,503 US6261791B1 (en) 1997-03-10 1999-05-25 Method for diagnosing cancer using specific PSCA antibodies
EP99966018A EP1135467B1 (en) 1998-12-02 1999-12-02 Psca: prostate stem cell antigen and uses thereof

Publications (1)

Publication Number Publication Date
CY1109022T1 true CY1109022T1 (el) 2014-07-02

Family

ID=27394602

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091100459T CY1109022T1 (el) 1998-12-02 2009-04-24 Psca: αντιγονο βλαστικου κυτταρου προστατη και χρησεις αυτου

Country Status (11)

Country Link
US (1) US6261791B1 (el)
EP (2) EP1135467B1 (el)
JP (2) JP4527883B2 (el)
AT (1) ATE423191T1 (el)
CA (1) CA2351887C (el)
CY (1) CY1109022T1 (el)
DE (1) DE69940436D1 (el)
DK (1) DK1135467T3 (el)
ES (1) ES2320606T3 (el)
PT (1) PT1135467E (el)
WO (1) WO2000032752A1 (el)

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Also Published As

Publication number Publication date
ATE423191T1 (de) 2009-03-15
WO2000032752A1 (en) 2000-06-08
PT1135467E (pt) 2009-04-24
WO2000032752A9 (en) 2001-06-07
CA2351887C (en) 2010-10-26
US6261791B1 (en) 2001-07-17
JP2009159973A (ja) 2009-07-23
DK1135467T3 (da) 2009-04-14
EP1135467B1 (en) 2009-02-18
CA2351887A1 (en) 2000-06-08
EP1135467A1 (en) 2001-09-26
JP2002531082A (ja) 2002-09-24
JP4527883B2 (ja) 2010-08-18
ES2320606T3 (es) 2009-05-25
EP1780268A3 (en) 2007-05-16
DE69940436D1 (de) 2009-04-02
EP1780268A2 (en) 2007-05-02

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