CY1108049T1 - Πεπτιδια με βαση την αλληλουχια της ανθρωπινης λακτοφερρινης και χρηση τους - Google Patents

Πεπτιδια με βαση την αλληλουχια της ανθρωπινης λακτοφερρινης και χρηση τους

Info

Publication number
CY1108049T1
CY1108049T1 CY20081100292T CY081100292T CY1108049T1 CY 1108049 T1 CY1108049 T1 CY 1108049T1 CY 20081100292 T CY20081100292 T CY 20081100292T CY 081100292 T CY081100292 T CY 081100292T CY 1108049 T1 CY1108049 T1 CY 1108049T1
Authority
CY
Cyprus
Prior art keywords
human lactoferrin
peptides
peptides based
amino acids
relates
Prior art date
Application number
CY20081100292T
Other languages
English (en)
Inventor
Lars A. Hanson
Inger Mattsby-Baltzer
Lars Baltzer
Gunnar T. Dolphin
Original Assignee
Pharmasurgics In Sweden Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9802441A external-priority patent/SE9802441D0/xx
Priority claimed from SE9802562A external-priority patent/SE9802562D0/xx
Application filed by Pharmasurgics In Sweden Ab filed Critical Pharmasurgics In Sweden Ab
Publication of CY1108049T1 publication Critical patent/CY1108049T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/04—Animal proteins
    • A23J3/08—Dairy proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

Η εφεύρεση αναφέρεται σε νέα πεπτίδια που σχηματίζονται από τουλάχιστον επτά ακόλουθα αμινοξέα των αμινοξέων στη θέση 12-40, που μετρούνται από το Ν-τελικό άκρο, στην αλληλουχία που συνιστά την ανθρώπινη λακτοφερρίνη, και κατά προτίμηση τροποποιήσεις αυτών. Η εφεύρεση επίσης αναφέρεται σε ιατρικά προϊόντα που περιλαμβάνουν αυτά τα πεπτίδια, που προορίζονται ιδιαίτερα για την αντιμετώπιση και πρόληψη των λοιμώξεων, φλεγμονών και όγκων. Περαιτέρω, η εφεύρεση αναφέρεται σε τρόφιμα, π.χ. παρασκευάσματα διατροφής για βρέφη, που περιλαμβάνουν τα προαναφερόμενα πεπτίδια.
CY20081100292T 1998-07-06 2008-03-14 Πεπτιδια με βαση την αλληλουχια της ανθρωπινης λακτοφερρινης και χρηση τους CY1108049T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE9802441A SE9802441D0 (sv) 1998-07-06 1998-07-06 New peptides and use thereof
SE9802562A SE9802562D0 (sv) 1998-07-17 1998-07-17 New peptides and use thereof
SE9804614A SE9804614A0 (en) 1998-07-06 1998-12-29 New peptides and use thereof
PCT/SE1999/001230 WO2000001730A1 (en) 1998-07-06 1999-07-06 Peptides based on the sequence of human lactoferrin and their use

Publications (1)

Publication Number Publication Date
CY1108049T1 true CY1108049T1 (el) 2012-05-23

Family

ID=27355931

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20081100292T CY1108049T1 (el) 1998-07-06 2008-03-14 Πεπτιδια με βαση την αλληλουχια της ανθρωπινης λακτοφερρινης και χρηση τους

Country Status (14)

Country Link
US (2) US7253143B1 (el)
EP (1) EP1095061B1 (el)
JP (2) JP4488622B2 (el)
AT (1) ATE381578T1 (el)
AU (1) AU752640B2 (el)
CA (1) CA2333306C (el)
CY (1) CY1108049T1 (el)
DE (1) DE69937798T2 (el)
DK (1) DK1095061T3 (el)
ES (1) ES2299253T3 (el)
NZ (1) NZ509622A (el)
PT (1) PT1095061E (el)
SE (1) SE9804614A0 (el)
WO (1) WO2000001730A1 (el)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9804614A0 (en) * 1998-07-06 2000-01-07 A+ Science Invest Ab New peptides and use thereof
SE0200598D0 (sv) * 2002-02-27 2002-02-27 A & Science Invest Ab Pharmaceutical composition and method for treatment or prevention of vascular disease or states of tissue hypoperfusion with hypoxic and/or ischemic consequences
AU2003293500A1 (en) * 2002-12-12 2004-07-09 Agennix Incorporated Lactoferrin in the reduction of pain
EP1737884B1 (en) 2004-03-19 2016-10-19 The University Of Queensland Alpha helical mimics, their uses and methods for their production
WO2006047744A2 (en) 2004-10-26 2006-05-04 Agennix Incorporated Compositions of lactoferrin related peptides and uses thereof
ATE501169T1 (de) * 2005-12-30 2011-03-15 Evonik Roehm Gmbh Lactoferrin-peptide, geeignet als in die zelle eindringende peptide
EP2078529B1 (en) * 2006-07-10 2014-12-10 PBA3 Biomed GmbH Antimicrobial peptides
AU2008206256A1 (en) 2007-01-16 2008-07-24 Rutgers, The State University Of New Jersey Natural polypeptides for oral health care
EP2050461A1 (en) 2007-10-19 2009-04-22 PharmaSurgics in Sweden AB Peptides based on the sequence of human lactoferrin and their use
EP2060586A1 (en) * 2007-11-14 2009-05-20 PharmaSurgics in Sweden AB New synthetic arginine substituted peptides and their use
NZ590254A (en) 2008-06-09 2012-07-27 Palatin Technologies Inc Melanocortin receptor-specific cyclic peptides for treatment of sexual dysfunction
EP2387390B1 (en) 2009-01-13 2012-11-28 PharmaSurgics in Sweden AB Hylauronic acid containing compositions for treatment of wounds, scars, post-surgical adhesion formation
UY32690A (es) 2009-06-08 2011-01-31 Astrazeneca Ab Péptidos específicos para receptores de melanocortina
EP2504352B1 (en) 2009-11-23 2018-11-14 Palatin Technologies, Inc. Melanocortin-1 receptor-specific cyclic peptides
AU2010321739A1 (en) 2009-11-23 2012-05-31 Palatin Technologies, Inc. Melanocortin-1 receptor-specific linear peptides
JP5177901B2 (ja) * 2009-12-02 2013-04-10 株式会社明治 栄養組成物
CN101891885B (zh) * 2010-08-18 2012-12-12 中国科学院长春应用化学研究所 聚丝氨酸酯及其制备方法
EP2481751A1 (en) * 2011-01-26 2012-08-01 PharmaSurgics in Sweden AB Human lactoferrin derived peptides
US20140255409A1 (en) * 2011-10-28 2014-09-11 Glycorex Transplantation Ab Method for extracorporeal elimination of one or more components from blood
JP5763024B2 (ja) * 2012-09-07 2015-08-12 株式会社明治 栄養組成物
US9850278B2 (en) 2013-04-25 2017-12-26 Carmel-Haifa University Economic Corp. Synthetic anti-inflammatory peptides and use thereof
SG10201811729PA (en) 2013-12-12 2019-02-27 Life Technologies Corp Membrane-penetrating peptides to enhance transfection and compositions and methods for using same
US12295990B2 (en) 2018-11-09 2025-05-13 The Wistar Institute Of Anatomy And Biology Use of lactoferrin for generating myeloid-derived suppressor cells

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2818056B2 (ja) 1990-09-07 1998-10-30 森永乳業株式会社 抗菌性ペプチドおよび抗菌剤
CA2128612C (en) 1992-01-23 1999-06-15 Mamoru Tomita Antimicrobial agents and method for treating products therewith
JP3312946B2 (ja) * 1993-03-04 2002-08-12 雪印乳業株式会社 ウイルス感染・増殖抑制剤
JP3347819B2 (ja) 1993-06-28 2002-11-20 森永乳業株式会社 抗菌性ペプチドの精製方法
JP3529423B2 (ja) 1994-04-01 2004-05-24 森永乳業株式会社 抗菌性ペプチドの製造方法
JP3738042B2 (ja) 1994-05-17 2006-01-25 森永乳業株式会社 非経口用抗腫瘍剤
JP3812957B2 (ja) 1994-08-02 2006-08-23 森永乳業株式会社 角膜損傷治療剤
JP3506274B2 (ja) 1994-09-01 2004-03-15 雪印乳業株式会社 新規ペプチドおよび免疫賦活剤
JPH08143468A (ja) 1994-11-17 1996-06-04 Morinaga Milk Ind Co Ltd 抗潰瘍剤
JP3830179B2 (ja) * 1995-07-31 2006-10-04 森永乳業株式会社 抗寄生虫剤
JPH09165342A (ja) 1995-12-14 1997-06-24 Morinaga Milk Ind Co Ltd 抗真菌剤
WO1998006425A1 (en) * 1996-08-12 1998-02-19 A+ Science Invest Ab Treatment and prevention of infections, inflammations and/or tumours with lactoferrin and/or lactoferricin
JPH1059864A (ja) 1996-08-15 1998-03-03 Morinaga Milk Ind Co Ltd 経口がん転移抑制剤
SE9804614A0 (en) * 1998-07-06 2000-01-07 A+ Science Invest Ab New peptides and use thereof

Also Published As

Publication number Publication date
JP2002519438A (ja) 2002-07-02
ATE381578T1 (de) 2008-01-15
US20080299180A1 (en) 2008-12-04
DK1095061T3 (da) 2008-04-21
AU752640B2 (en) 2002-09-26
WO2000001730A1 (en) 2000-01-13
SE9804614A0 (en) 2000-01-07
CA2333306C (en) 2011-12-06
EP1095061A1 (en) 2001-05-02
JP4488622B2 (ja) 2010-06-23
HK1036630A1 (en) 2002-01-11
DE69937798T2 (de) 2009-04-30
US7803757B2 (en) 2010-09-28
SE9804614L (el) 1900-01-01
SE9804614D0 (sv) 1998-12-29
EP1095061B1 (en) 2007-12-19
AU5076099A (en) 2000-01-24
JP2010090162A (ja) 2010-04-22
DE69937798D1 (de) 2008-01-31
NZ509622A (en) 2003-05-30
ES2299253T3 (es) 2008-05-16
PT1095061E (pt) 2008-03-10
CA2333306A1 (en) 2000-01-13
US7253143B1 (en) 2007-08-07

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