CY1107855T1 - Συνθεσεις που σχηματιζουν σωματιδια οι οποιες περιεχουν τηγμενα πυρρολοκαρβαζολια - Google Patents

Συνθεσεις που σχηματιζουν σωματιδια οι οποιες περιεχουν τηγμενα πυρρολοκαρβαζολια

Info

Publication number
CY1107855T1
CY1107855T1 CY20081100044T CY081100044T CY1107855T1 CY 1107855 T1 CY1107855 T1 CY 1107855T1 CY 20081100044 T CY20081100044 T CY 20081100044T CY 081100044 T CY081100044 T CY 081100044T CY 1107855 T1 CY1107855 T1 CY 1107855T1
Authority
CY
Cyprus
Prior art keywords
pyrolocarables
magnified
particles containing
forming particles
compositions forming
Prior art date
Application number
CY20081100044T
Other languages
English (en)
Inventor
David A Dickason
Piyush R Patel
Vincent Corvari
Efraim Shek
Joseph L Herman
Jeffry M Skell
Original Assignee
Cephalon, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26790393&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1107855(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cephalon, Inc. filed Critical Cephalon, Inc.
Publication of CY1107855T1 publication Critical patent/CY1107855T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Αποκαλύπτεται μια μη υδατική σύνθεση που σχηματίζει σωματίδια η οποία περιέχει τηγμένα πυρρολοκαρβαζόλια. Κατά την επαφή με ένα υδατικό μέσο, η σύνθεση που σχηματίζει σωματίδια διασκορπίζεται αυθόρμητα σε αιωρούμενα σωματίδια, οπότε διαμορφώνεται ένα σταθερό εναιώρημα το οποίο παρέχει σημαντικά βελτιωμένη βιοδιαθεσιμότητα των στοματικά χορηγούμενων τηγμένων ενώσεων πυρρολοκαρβαζολίου.
CY20081100044T 1998-08-06 2008-01-11 Συνθεσεις που σχηματιζουν σωματιδια οι οποιες περιεχουν τηγμενα πυρρολοκαρβαζολια CY1107855T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9561198P 1998-08-06 1998-08-06
US09/368,409 US6200968B1 (en) 1998-08-06 1999-08-05 Particle-forming compositions containing fused pyrrolocarbazoles
EP99940914A EP1102758B1 (en) 1998-08-06 1999-08-06 Particle-forming compositions containing fused pyrrolocarbazoles

Publications (1)

Publication Number Publication Date
CY1107855T1 true CY1107855T1 (el) 2013-06-19

Family

ID=26790393

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20081100044T CY1107855T1 (el) 1998-08-06 2008-01-11 Συνθεσεις που σχηματιζουν σωματιδια οι οποιες περιεχουν τηγμενα πυρρολοκαρβαζολια

Country Status (17)

Country Link
US (2) US6200968B1 (el)
EP (1) EP1102758B1 (el)
JP (1) JP2003524597A (el)
KR (1) KR100616388B1 (el)
CN (1) CN1314900A (el)
AT (1) ATE375986T1 (el)
AU (1) AU756865C (el)
CA (1) CA2338546C (el)
CY (1) CY1107855T1 (el)
DE (1) DE69937351T2 (el)
DK (1) DK1102758T3 (el)
ES (1) ES2296401T3 (el)
HK (1) HK1037622A1 (el)
MX (1) MXPA01001352A (el)
NZ (1) NZ509596A (el)
PT (1) PT1102758E (el)
WO (1) WO2000008004A1 (el)

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US6200968B1 (en) * 1998-08-06 2001-03-13 Cephalon, Inc. Particle-forming compositions containing fused pyrrolocarbazoles
MXPA01003761A (es) * 1998-10-13 2003-07-21 Kyowa Hakko Kogyo Kk Agente para tratar oftalmopatia.
PL215226B1 (pl) 2000-10-11 2013-11-29 Cephalon Kompozycja farmaceutyczna zawierajaca zwiazek modafinilu, sposób jej wytwarzania oraz jej zastosowanie
US6489363B2 (en) 2000-10-11 2002-12-03 Cephalon, Inc. Pharmaceutical solutions of modafinil compounds
US6919378B2 (en) * 2000-10-11 2005-07-19 Cephalon, Inc. Pharmaceutical solutions of modafinil compounds
US7704975B2 (en) * 2000-12-19 2010-04-27 Cephalon, Inc. Modafinil compound and cyclodextrin mixtures
US7141555B2 (en) 2000-12-19 2006-11-28 Cephalon, Inc. Modafinil compound and cyclodextrin mixtures
JP2005536516A (ja) * 2002-07-23 2005-12-02 ノバルティス アクチエンゲゼルシャフト 薬剤、軟膏基剤および可溶化剤／分散剤を含む、眼科用軟膏組成物
RS20050789A (sr) 2003-05-01 2008-04-04 Bristol-Myers Squibb Company, Aril-supstituisana jedinjenja pirazol-amida pogodna za primenu kao inhibitori kinaze
DE10341043A1 (de) * 2003-09-03 2005-03-31 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue oral zu applizierende Darreichungsform für 3-[(2-{[4-Hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester und dessen Salze
US20050107438A1 (en) * 2003-09-03 2005-05-19 Boehringer Ingelheim International Gmbh Pharmaceutical composition comprising 3-[(2-{[4-(Hexyloxycarbonylaminoiminomethyl) phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester or a salt therefore
US7241779B2 (en) * 2003-12-23 2007-07-10 Cephalon, Inc. Fused pyrrolocarbazoles
US7255687B2 (en) * 2004-11-19 2007-08-14 Percutaneous Systems, Inc. Systems and methods for luminal access
WO2007002670A2 (en) * 2005-06-28 2007-01-04 Bausch & Lomb Incorporated Method of lowering intraocular pressure
JP2009518435A (ja) * 2005-12-09 2009-05-07 アボット・ラボラトリーズ 結晶性レスタウルチニブ水和物および結晶性レスタウルチニブ半水和物半アセトニトリル和物および結晶性レスタウルチニブ半水和物半テトラヒドロフラン和物
US20080021013A1 (en) * 2006-07-21 2008-01-24 Cephalon, Inc. JAK inhibitors for treatment of myeloproliferative disorders
WO2009067221A2 (en) * 2007-11-20 2009-05-28 Cephalon, Inc. Microemulsion containing indolocarbazole compound and dosage forms containing the same
EP2238973A1 (en) 2009-04-07 2010-10-13 Cephalon France Lyophilized preparations of proteasome inhibitors
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Also Published As

Publication number Publication date
DE69937351T2 (de) 2008-07-17
EP1102758A4 (en) 2002-07-24
EP1102758A1 (en) 2001-05-30
AU5467499A (en) 2000-02-28
CN1314900A (zh) 2001-09-26
CA2338546A1 (en) 2000-02-17
US6200968B1 (en) 2001-03-13
CA2338546C (en) 2010-02-09
AU756865C (en) 2004-02-26
ES2296401T3 (es) 2008-04-16
DE69937351D1 (de) 2007-11-29
US6660729B1 (en) 2003-12-09
WO2000008004A1 (en) 2000-02-17
HK1037622A1 (en) 2002-02-15
MXPA01001352A (es) 2002-04-24
EP1102758B1 (en) 2007-10-17
ATE375986T1 (de) 2007-11-15
KR100616388B1 (ko) 2006-08-29
JP2003524597A (ja) 2003-08-19
WO2000008004A8 (en) 2000-06-22
PT1102758E (pt) 2008-01-23
KR20010079618A (ko) 2001-08-22
NZ509596A (en) 2004-07-30
DK1102758T3 (da) 2008-02-04
AU756865B2 (en) 2003-01-23

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