ATE375986T1 - Partikelformende zubereitungen welche kondensierte pyrrolocarbazole enhalten - Google Patents

Partikelformende zubereitungen welche kondensierte pyrrolocarbazole enhalten

Info

Publication number
ATE375986T1
ATE375986T1 AT99940914T AT99940914T ATE375986T1 AT E375986 T1 ATE375986 T1 AT E375986T1 AT 99940914 T AT99940914 T AT 99940914T AT 99940914 T AT99940914 T AT 99940914T AT E375986 T1 ATE375986 T1 AT E375986T1
Authority
AT
Austria
Prior art keywords
particle
forming
preparations containing
containing condensed
forming preparations
Prior art date
Application number
AT99940914T
Other languages
English (en)
Inventor
David Dickason
Piyush Patel
Vincent Corvari
Efraim Shek
Joseph Herman
Jeffry Skell
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26790393&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE375986(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cephalon Inc filed Critical Cephalon Inc
Application granted granted Critical
Publication of ATE375986T1 publication Critical patent/ATE375986T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
AT99940914T 1998-08-06 1999-08-06 Partikelformende zubereitungen welche kondensierte pyrrolocarbazole enhalten ATE375986T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9561198P 1998-08-06 1998-08-06
US09/368,409 US6200968B1 (en) 1998-08-06 1999-08-05 Particle-forming compositions containing fused pyrrolocarbazoles

Publications (1)

Publication Number Publication Date
ATE375986T1 true ATE375986T1 (de) 2007-11-15

Family

ID=26790393

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99940914T ATE375986T1 (de) 1998-08-06 1999-08-06 Partikelformende zubereitungen welche kondensierte pyrrolocarbazole enhalten

Country Status (17)

Country Link
US (2) US6200968B1 (de)
EP (1) EP1102758B1 (de)
JP (1) JP2003524597A (de)
KR (1) KR100616388B1 (de)
CN (1) CN1314900A (de)
AT (1) ATE375986T1 (de)
AU (1) AU756865C (de)
CA (1) CA2338546C (de)
CY (1) CY1107855T1 (de)
DE (1) DE69937351T2 (de)
DK (1) DK1102758T3 (de)
ES (1) ES2296401T3 (de)
HK (1) HK1037622A1 (de)
MX (1) MXPA01001352A (de)
NZ (1) NZ509596A (de)
PT (1) PT1102758E (de)
WO (1) WO2000008004A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6200968B1 (en) * 1998-08-06 2001-03-13 Cephalon, Inc. Particle-forming compositions containing fused pyrrolocarbazoles
US7795246B2 (en) * 1998-08-06 2010-09-14 Cephalon, Inc. Particle-forming compositions containing fused pyrrolocarbazoles
MXPA01003761A (es) * 1998-10-13 2003-07-21 Kyowa Hakko Kogyo Kk Agente para tratar oftalmopatia.
CN100584322C (zh) 2000-10-11 2010-01-27 赛福伦公司 包含莫达非尼化合物的组合物
US6919378B2 (en) * 2000-10-11 2005-07-19 Cephalon, Inc. Pharmaceutical solutions of modafinil compounds
US6489363B2 (en) 2000-10-11 2002-12-03 Cephalon, Inc. Pharmaceutical solutions of modafinil compounds
US7704975B2 (en) * 2000-12-19 2010-04-27 Cephalon, Inc. Modafinil compound and cyclodextrin mixtures
US7141555B2 (en) 2000-12-19 2006-11-28 Cephalon, Inc. Modafinil compound and cyclodextrin mixtures
JP2005536516A (ja) * 2002-07-23 2005-12-02 ノバルティス アクチエンゲゼルシャフト 薬剤、軟膏基剤および可溶化剤／分散剤を含む、眼科用軟膏組成物
UA81668C2 (en) 2003-05-01 2008-01-25 Бристол-Майерс Сквибб Компани Normal;heading 1;heading 2;ARYL-SUBSTITUTED PYRAZOLE-AMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS
US20050107438A1 (en) * 2003-09-03 2005-05-19 Boehringer Ingelheim International Gmbh Pharmaceutical composition comprising 3-[(2-{[4-(Hexyloxycarbonylaminoiminomethyl) phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester or a salt therefore
DE10341043A1 (de) * 2003-09-03 2005-03-31 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue oral zu applizierende Darreichungsform für 3-[(2-{[4-Hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester und dessen Salze
US7241779B2 (en) * 2003-12-23 2007-07-10 Cephalon, Inc. Fused pyrrolocarbazoles
US7255687B2 (en) * 2004-11-19 2007-08-14 Percutaneous Systems, Inc. Systems and methods for luminal access
US20060293378A1 (en) * 2005-06-28 2006-12-28 Mcintire Gregory Method of lowering intraocular pressure
US20070135628A1 (en) * 2005-12-09 2007-06-14 Walter Dziki Crystalline lestaurtinib hydrates and crystalline lestaurtinib hemihydrate hemiacetonitrileate and crystalline lestaurtinib hemihydrate hemitetrahydrofuranate
US20080021013A1 (en) * 2006-07-21 2008-01-24 Cephalon, Inc. JAK inhibitors for treatment of myeloproliferative disorders
WO2009067221A2 (en) * 2007-11-20 2009-05-28 Cephalon, Inc. Microemulsion containing indolocarbazole compound and dosage forms containing the same
EP2238973A1 (de) 2009-04-07 2010-10-13 Cephalon France Lyophilisierte Präparate von Proteasominhibitoren
US11198831B2 (en) 2019-01-31 2021-12-14 Kvi Llc Lubricant for a device

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3906108A (en) * 1973-10-12 1975-09-16 Johnson & Johnson Stabilized tretinoin cream emulsion
IE52125B1 (en) * 1980-10-02 1987-06-24 Fox Charles L Jun 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quino-line carboxylic acid and metal salts thereof useful in burn therapy
JPS62120388A (ja) 1985-11-19 1987-06-01 Meiji Seika Kaisha Ltd Ｓｆ−２３７０物質ハロゲン化誘導体とその製造法
JPS62155284A (ja) 1985-12-27 1987-07-10 Kyowa Hakko Kogyo Co Ltd 生理活性物質ｋ−２５２の誘導体
JPS62155285A (ja) 1985-12-27 1987-07-10 Kyowa Hakko Kogyo Co Ltd 生理活性物質ｋ−２５２の誘導体
JPH0826037B2 (ja) 1987-01-22 1996-03-13 協和醗酵工業株式会社 生理活性物質ｋ−２５２の誘導体
JPH0826036B2 (ja) 1987-01-22 1996-03-13 協和醗酵工業株式会社 生理活性物質ｋ−２５２の誘導体
US4923986A (en) 1987-03-09 1990-05-08 Kyowa Hakko Kogyo Co., Ltd. Derivatives of physiologically active substance K-252
US5093330A (en) 1987-06-15 1992-03-03 Ciba-Geigy Corporation Staurosporine derivatives substituted at methylamino nitrogen
JPH07113027B2 (ja) 1987-12-24 1995-12-06 協和醗酵工業株式会社 Ｋ−２５２誘導体
DE3924538A1 (de) 1989-07-25 1991-01-31 Goedecke Ag Indolocarbazol und dessen verwendung
US5242932A (en) * 1991-12-17 1993-09-07 The Rockefeller University Treatment of amyloidosis associated with alzheimer disease
JPH04124123A (ja) * 1990-08-31 1992-04-24 Kao Corp 口腔用組成物
JP2937446B2 (ja) 1990-09-14 1999-08-23 株式会社資生堂 白髪防止黒化剤
GB9022788D0 (en) * 1990-10-19 1990-12-05 Cortecs Ltd Pharmaceutical formulations
NZ242467A (en) 1991-07-03 1995-06-27 Regeneron Pharma Methods and compositions using oligonucleotides to treat mammalian tumour cells expressing neurotrophic factors
CA2123096A1 (en) 1991-11-08 1993-05-13 Beat J. Knusel Compositions containing k-252 compounds for potentiation of neurotrophin activity
US5621100A (en) 1992-07-24 1997-04-15 Cephalon, Inc. K-252a derivatives for treatment of neurological disorders
US5621101A (en) 1992-07-24 1997-04-15 Cephalon, Inc. Protein kinase inhibitors for treatment of neurological disorders
US5756494A (en) * 1992-07-24 1998-05-26 Cephalon, Inc. Protein kinase inhibitors for treatment of neurological disorders
US5461146A (en) 1992-07-24 1995-10-24 Cephalon, Inc. Selected protein kinase inhibitors for the treatment of neurological disorders
EP0699204B1 (de) 1993-05-28 1998-04-15 Cephalon, Inc. Anwendung von indolocarbazol-derivaten zur behandlung von prostataerkrankungen
US5468872A (en) 1993-09-16 1995-11-21 Cephalon, Inc. K-252a functional derivatives potentiate neurotrophin-3 for the treatment of neurological disorders
GB9325395D0 (en) * 1993-12-11 1994-02-16 Ciba Geigy Ag Compositions
AU1911095A (en) * 1994-02-18 1995-09-04 Cephalon, Inc. Aqueous indolocarbazole solutions
WO1996003113A1 (en) * 1994-07-22 1996-02-08 G.D. Searle & Co. Self-emulsifying drug delivery system
US5705511A (en) 1994-10-14 1998-01-06 Cephalon, Inc. Fused pyrrolocarbazoles
US5475110A (en) 1994-10-14 1995-12-12 Cephalon, Inc. Fused Pyrrolocarbazoles
US5594009A (en) 1994-10-14 1997-01-14 Cephalon, Inc. Fused pyrrolocarbazoles
US5591855A (en) 1994-10-14 1997-01-07 Cephalon, Inc. Fused pyrrolocarbazoles
EP0711556A1 (de) * 1994-11-09 1996-05-15 Ciba-Geigy Ag Intravenöse Lösungen für ein Staurosporinderivat
EP0733372A3 (de) * 1995-03-21 1998-05-20 Ciba-Geigy Ag Pharmazeutische Formulierungsgrundlage für Nanosuspensionen
US5686444A (en) * 1995-04-05 1997-11-11 Cephalon, Inc. Selected soluble esters of hydroxyl-containing indolocarbazoles
US5616724A (en) 1996-02-21 1997-04-01 Cephalon, Inc. Fused pyrrolo[2,3-c]carbazole-6-ones
UA67725C2 (en) 1996-06-03 2004-07-15 Cephalon Inc K-252a derivatives and a method for improvement of functioning and cell survival enhancement
DK0850646T3 (da) * 1996-06-18 2008-05-13 Kyowa Hakko Kogyo Kk Liposompræparater af indolocarbazol-derivater
DE69715862T2 (de) * 1996-06-25 2003-04-10 Cephalon, Inc. Verwendung eines k-252a derivats zur behandlung von periphärer oder zentraler nervenerkrankungen und übermässiger cytokinbildung
US6200968B1 (en) * 1998-08-06 2001-03-13 Cephalon, Inc. Particle-forming compositions containing fused pyrrolocarbazoles
GB9903547D0 (en) * 1999-02-16 1999-04-07 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
EP1102758A1 (de) 2001-05-30
DK1102758T3 (da) 2008-02-04
WO2000008004A1 (en) 2000-02-17
KR20010079618A (ko) 2001-08-22
CY1107855T1 (el) 2013-06-19
JP2003524597A (ja) 2003-08-19
ES2296401T3 (es) 2008-04-16
NZ509596A (en) 2004-07-30
AU756865B2 (en) 2003-01-23
DE69937351D1 (de) 2007-11-29
MXPA01001352A (es) 2002-04-24
KR100616388B1 (ko) 2006-08-29
CA2338546A1 (en) 2000-02-17
AU5467499A (en) 2000-02-28
EP1102758B1 (de) 2007-10-17
HK1037622A1 (en) 2002-02-15
DE69937351T2 (de) 2008-07-17
AU756865C (en) 2004-02-26
EP1102758A4 (de) 2002-07-24
CA2338546C (en) 2010-02-09
PT1102758E (pt) 2008-01-23
US6660729B1 (en) 2003-12-09
CN1314900A (zh) 2001-09-26
US6200968B1 (en) 2001-03-13
WO2000008004A8 (en) 2000-06-22

Similar Documents

Publication Publication Date Title
CY1107855T1 (el) Συνθεσεις που σχηματιζουν σωματιδια οι οποιες περιεχουν τηγμενα πυρρολοκαρβαζολια
HUP0004468A2 (hu) Eletriptán-hemiszulfátot és koffeint tartalmazó gyógyszerkészítmény
DE69936386D1 (de) Sprühgetrocknete proteinformulierungen
ATE215954T1 (de) Pyrazolo(4,3-d)pyrimidin-derivate und diese enthaltende pharmazeutische zubereitungen
EA199900331A1 (ru) Препарат из покрытых частиц
SI1155015T1 (sl) Postopek za proizvodnjo terc.-butil (E)-(6-(2-(4-(4-fluorofenil)-6- izopropil-2-(metil(metilsulfonil)amino)pirimidin-5-il)vinil)(4R,6S)-2, 2-dimetil-(1,3)dioksan-4-il)acetata
ATE474555T1 (de) Aerosol-zusammensetzung
NO855208L (no) Fremgangsmaate ved fremstilling av frittstroemmende, reagglomereringsresistente polymerpartikler.
ATE231149T1 (de) (1,8)-naphthyridinderivate derivate mit antiviraler wirkung
EA199700281A1 (ru) Молекула днк, кодирующая белок l1 вируса папилломы типа 11 чепловека, экспрессирующий вектор, способ получения очищенных вирусоподобных частиц
NO992780L (no) Forbedrede farmas°ytiske preparater
DE69939555D1 (de) Granuliertes Brotverbesserungmittel zur Herstellung von Teigwaren
ES2196743T3 (es) Sorbitol en polvo y su procedimiento de preparacion.
NO903112D0 (no) Fremgangsmaate for fremstilling av 3-substituerte vinylcefalosporinderivater.
NO20062381L (no) Partikkeldannende sammensetninger inneholdende kondenserte pyrrolokarbazoler
BR0114380A (pt) Derivados-1-aminobutan-3-ol-substituìdos
FI941136A0 (fi) Kamferin piperatsinyyli(sulfonyyli)amidijohdannaiset oksitosiiniantagonisteina
CY1106712T1 (el) Υποκατεστημενα παραγωγα 5-αμινο-1-πεντεν-3-ολης
EA200200294A1 (ru) Сферические агломераты телитромицина, способ их получения и их применение для приготовления лекарственных форм
EA200101106A1 (ru) Фармацевтический комплекс
EA200200486A1 (ru) Пероральный раствор, содержащий галантамин и подсластитель
DK0790994T3 (da) Heterocyclisk substituerede propensyrederivater som NMDA-antagonister
PT1133495E (pt) Semi-hidrocloreto do acido 8-ciano-1-ciclopropil-7-(1s,6s-2,8-diazabiciclo-¬4.3.0|-nonano-8-il)-6-fluoro-1,4-diidro-4-oxo-3-quinolinocarboxilico
DK0662835T3 (da) Nye farmaceutiske præparater af spiramycin
EA200100107A1 (ru) Новые 2,3,3a,4,9,9a-гексагидро-8-гидрокси-1h-бенз[f]индолы, способ их получения и их применение в качестве лекарственных средств

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1102758

Country of ref document: EP