CY1107627T1 - Βελτιωμενα εμβολια dna για τον ιο του βοειου απλου ερπητα-1 - Google Patents

Βελτιωμενα εμβολια dna για τον ιο του βοειου απλου ερπητα-1

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Publication number
CY1107627T1
CY1107627T1 CY20071100201T CY071100201T CY1107627T1 CY 1107627 T1 CY1107627 T1 CY 1107627T1 CY 20071100201 T CY20071100201 T CY 20071100201T CY 071100201 T CY071100201 T CY 071100201T CY 1107627 T1 CY1107627 T1 CY 1107627T1
Authority
CY
Cyprus
Prior art keywords
herpes virus
dna vaccines
aliphatic radical
bovine herpes
enhanced dna
Prior art date
Application number
CY20071100201T
Other languages
English (en)
Inventor
Jean-Christophe Audonnet
Laurent Bernard Fischer
Simona Barzu-Le-Roux
Original Assignee
Merial
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial filed Critical Merial
Publication of CY1107627T1 publication Critical patent/CY1107627T1/el

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Εμβόλιο DNA κατά ενός παθογόνου που προσβάλλει τα προσοδοφόρα ζώα, ειδικά τα βοοειδή ή τους χοίρους, περιλαμβάνον ένα πλασμίδιο περιέχον μία αλληλουχία νουκλεοτιδίων η οποία κωδικοποιεί ένα ανοσογόνο ενός παθογόνου του θεωρούμενου ζωικού είδους, υπό συνθήκες επιτρέπουσες την έκφραση in vivo αυτής της αλληλουχίας, και ένα κατιονικό λιπίδιο περιέχον ένα άλας τεταρτοταγούς αμμωνίου, τύπου (I) στον οποίο το R1 είναι μία γραμμική, κορεσμένη ή ακόρεστη, αλειφατική ρίζα, έχουσα 12 έως 18 άτομα άνθρακα, το R2 είναι μία άλλη αλειφατική ρίζα, περιέχουσα 2 ή 3 άτομα άνθρακα, και το Χ μία ομάδα υδροξυλίου ή αμίνης, όπου αυτό το λιπίδιο είναι κατά προτίμηση το DMRIE.
CY20071100201T 2000-01-21 2007-02-14 Βελτιωμενα εμβολια dna για τον ιο του βοειου απλου ερπητα-1 CY1107627T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0000798A FR2804028B1 (fr) 2000-01-21 2000-01-21 Vaccins adn ameliores pour animaux de rente
EP01907651A EP1248650B1 (fr) 2000-01-21 2001-01-19 Vaccins adn ameliores pour herpesvirus-1 bovin

Publications (1)

Publication Number Publication Date
CY1107627T1 true CY1107627T1 (el) 2013-04-18

Family

ID=8846183

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071100201T CY1107627T1 (el) 2000-01-21 2007-02-14 Βελτιωμενα εμβολια dna για τον ιο του βοειου απλου ερπητα-1

Country Status (21)

Country Link
EP (1) EP1248650B1 (el)
JP (1) JP2004500375A (el)
KR (1) KR100820893B1 (el)
CN (2) CN1404398B (el)
AR (1) AR027926A1 (el)
AT (1) ATE346611T1 (el)
AU (1) AU783865B2 (el)
BR (2) BR0107767A (el)
CA (1) CA2398229C (el)
CY (1) CY1107627T1 (el)
DE (1) DE60124862T2 (el)
DK (1) DK1248650T3 (el)
ES (1) ES2277913T3 (el)
FR (1) FR2804028B1 (el)
HU (1) HU229597B1 (el)
MX (1) MXPA02007110A (el)
NZ (1) NZ520270A (el)
PL (1) PL209304B1 (el)
PT (1) PT1248650E (el)
WO (1) WO2001052888A2 (el)
ZA (1) ZA200205698B (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852705B2 (en) 2000-01-21 2005-02-08 Merial DNA vaccines for farm animals, in particular bovines and porcines
US7078388B2 (en) 2000-01-21 2006-07-18 Merial DNA vaccines for farm animals, in particular bovines and porcines
CA2756797C (en) * 2002-12-23 2015-05-05 Vical Incorporated Codon-optimized polynucleotide-based vaccines against human cytomegalovirus infection
EP1594537B1 (en) * 2003-02-19 2012-10-24 Merial Vaccination or immunization using a prime-boost regimen against brsv, bhv-1, bvdv, bpi-3
US20050214316A1 (en) 2003-11-13 2005-09-29 Brown Thomas P Methods of characterizing infectious bursal disease virus
CU23544A1 (es) 2006-02-28 2010-06-17 Ct Ingenieria Genetica Biotech Antígenos vacunales quiméricos contra el virus de la peste porcina clásica
US7862821B2 (en) 2006-06-01 2011-01-04 Merial Limited Recombinant vaccine against bluetongue virus
EP3590533A1 (en) * 2009-05-22 2020-01-08 Genocea Biosciences, Inc. Vaccines against herpes simplex virus type 2: compositions and methods for eliciting an immune response
CN103547286B (zh) * 2010-11-19 2016-10-19 北京凯因科技股份有限公司 一种用于预防和治疗乙型肝炎的dna疫苗组合物
CN112034169A (zh) * 2020-08-27 2020-12-04 华威特(江苏)生物制药有限公司 用于检测牛病毒性腹泻病毒1型的直接免疫荧光试剂及其试剂盒

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9304089A (es) * 1992-07-08 1994-01-31 Schering Corp Uso de gm-csf como una vacuna adyuvante.
EP1624068A1 (en) * 1993-06-01 2006-02-08 Life Technologies Inc. Genetic immunization with cationic lipids
US5658785A (en) * 1994-06-06 1997-08-19 Children's Hospital, Inc. Adeno-associated virus materials and methods
WO1996007739A2 (en) * 1994-09-09 1996-03-14 Neurocrine Biosciences, Incorporated Interleukin-1 type 3 receptors
US5736524A (en) * 1994-11-14 1998-04-07 Merck & Co.,. Inc. Polynucleotide tuberculosis vaccine
US5719131A (en) * 1994-12-09 1998-02-17 Genzyme Corporation Cationic amphiphiles containing dialkylamine lipophilic groups for intracellular delivery of therapeutic molecules
CA2214029A1 (en) * 1995-04-25 1996-10-31 Magda Marquet Single-vial formulations of dna/lipid complexes
JPH11508231A (ja) * 1995-05-26 1999-07-21 ソマティックス セラピー コーポレイション 安定な脂質/核酸複合体を含む送達ビヒクル
FR2751228B1 (fr) * 1996-07-19 1998-11-20 Rhone Merieux Vaccin polynucleotidique bovin pour voie intradermique
FR2751229B1 (fr) * 1996-07-19 1998-11-27 Rhone Merieux Formule de vaccin polynucleotidique notamment contre la pathologie respiratoire des bovins
FR2751224B1 (fr) * 1996-07-19 1998-11-20 Rhone Merieux Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs
AU1987197A (en) * 1997-03-10 1998-09-29 Heather Lynn Davis Gene delivery to mucosal epithelium for immunization or therapeutic purpose
AUPO856097A0 (en) * 1997-08-14 1997-09-04 Commonwealth Scientific And Industrial Research Organisation Vector
BR0011732B1 (pt) * 1999-06-10 2014-02-04 Vacinas de dna para animais de companhia e de esporte
US6943152B1 (en) * 1999-06-10 2005-09-13 Merial DNA vaccine-PCV

Also Published As

Publication number Publication date
CN101554480A (zh) 2009-10-14
DK1248650T3 (da) 2007-04-16
EP1248650A2 (fr) 2002-10-16
CA2398229C (en) 2012-05-15
BRPI0107767B1 (pt) 2017-10-24
HUP0203974A3 (en) 2004-07-28
AU3556601A (en) 2001-07-31
PT1248650E (pt) 2007-02-28
BR0107767A (pt) 2002-11-12
AR027926A1 (es) 2003-04-16
EP1248650B1 (fr) 2006-11-29
NZ520270A (en) 2004-08-27
WO2001052888A3 (fr) 2001-12-20
HUP0203974A2 (hu) 2003-03-28
CN1404398A (zh) 2003-03-19
ES2277913T3 (es) 2007-08-01
FR2804028A1 (fr) 2001-07-27
CN1404398B (zh) 2012-05-02
CA2398229A1 (en) 2001-07-26
KR100820893B1 (ko) 2008-04-10
DE60124862D1 (de) 2007-01-11
FR2804028B1 (fr) 2004-06-04
PL209304B1 (pl) 2011-08-31
DE60124862T2 (de) 2007-07-05
ATE346611T1 (de) 2006-12-15
AU783865B2 (en) 2005-12-15
PL356554A1 (en) 2004-06-28
KR20020084093A (ko) 2002-11-04
HU229597B1 (en) 2014-02-28
MXPA02007110A (es) 2003-01-28
JP2004500375A (ja) 2004-01-08
ZA200205698B (en) 2003-09-29
WO2001052888A2 (fr) 2001-07-26

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