HUP0203974A2 - Javított DNS-oltóanyagok háziállatokhoz - Google Patents

Javított DNS-oltóanyagok háziállatokhoz

Info

Publication number
HUP0203974A2
HUP0203974A2 HU0203974A HUP0203974A HUP0203974A2 HU P0203974 A2 HUP0203974 A2 HU P0203974A2 HU 0203974 A HU0203974 A HU 0203974A HU P0203974 A HUP0203974 A HU P0203974A HU P0203974 A2 HUP0203974 A2 HU P0203974A2
Authority
HU
Hungary
Prior art keywords
production
pathogen
lipid
dna vaccines
carbon atoms
Prior art date
Application number
HU0203974A
Other languages
English (en)
Inventor
Jean-Christophe Francis Audonnet
Simona Barzu-Le-Roux
Laurent Bernard Fischer
Original Assignee
Merial
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial filed Critical Merial
Publication of HUP0203974A2 publication Critical patent/HUP0203974A2/hu
Publication of HUP0203974A3 publication Critical patent/HUP0203974A3/hu
Publication of HU229597B1 publication Critical patent/HU229597B1/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A találmány tárgyát képezi DNS-oltóanyag egy háziállatokat, különösenszarvasmarhákat és sertéseket fertőző kórokozó ellen, amely az adottállatfaj egy kórokozójának egy immunogénjét kódolónukleotidszekvenciát tartalmazó plazmidot tartalmaz olyan módon, amelylehetővé teszi a szekvencia in vivo expresszióját, továbbá (I)általános képletű, kvaterner ammóniumsót tartalmazó kationos lipidettartalmaz, ahol a képletben R1 jelentése telített vagy telítetlen,egyenesláncú 12-18 szénatomszámú alifás csoport, R2 egy másik, 2-3szénatomszámú alifás csoport, X jelentése pedig hidroxil- vagyaminocsoport, ez a lipid pedig előnyösen a DMRIE. Ó
HU0203974A 2000-01-21 2001-01-19 Improved dna vaccines for production-type animals HU229597B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0000798A FR2804028B1 (fr) 2000-01-21 2000-01-21 Vaccins adn ameliores pour animaux de rente
PCT/FR2001/000187 WO2001052888A2 (fr) 2000-01-21 2001-01-19 Vaccins adn ameliores pour animaux de rente

Publications (3)

Publication Number Publication Date
HUP0203974A2 true HUP0203974A2 (hu) 2003-03-28
HUP0203974A3 HUP0203974A3 (en) 2004-07-28
HU229597B1 HU229597B1 (en) 2014-02-28

Family

ID=8846183

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0203974A HU229597B1 (en) 2000-01-21 2001-01-19 Improved dna vaccines for production-type animals

Country Status (21)

Country Link
EP (1) EP1248650B1 (hu)
JP (1) JP2004500375A (hu)
KR (1) KR100820893B1 (hu)
CN (2) CN1404398B (hu)
AR (1) AR027926A1 (hu)
AT (1) ATE346611T1 (hu)
AU (1) AU783865B2 (hu)
BR (2) BRPI0107767B1 (hu)
CA (1) CA2398229C (hu)
CY (1) CY1107627T1 (hu)
DE (1) DE60124862T2 (hu)
DK (1) DK1248650T3 (hu)
ES (1) ES2277913T3 (hu)
FR (1) FR2804028B1 (hu)
HU (1) HU229597B1 (hu)
MX (1) MXPA02007110A (hu)
NZ (1) NZ520270A (hu)
PL (1) PL209304B1 (hu)
PT (1) PT1248650E (hu)
WO (1) WO2001052888A2 (hu)
ZA (1) ZA200205698B (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852705B2 (en) 2000-01-21 2005-02-08 Merial DNA vaccines for farm animals, in particular bovines and porcines
US7078388B2 (en) 2000-01-21 2006-07-18 Merial DNA vaccines for farm animals, in particular bovines and porcines
EP1587816B1 (en) 2002-12-23 2010-06-16 Vical Incorporated Codon-optimized polynucleotide-based vaccines against human cytomegalovirus infection
EP1594537B1 (en) * 2003-02-19 2012-10-24 Merial Vaccination or immunization using a prime-boost regimen against brsv, bhv-1, bvdv, bpi-3
ES2417019T3 (es) 2003-11-13 2013-08-05 University Of Georgia Research Foundation, Inc. Procedimiento de caracterización del virus de la enfermedad de la bursitis infecciosa
CU23544A1 (es) 2006-02-28 2010-06-17 Ct Ingenieria Genetica Biotech Antígenos vacunales quiméricos contra el virus de la peste porcina clásica
US7862821B2 (en) 2006-06-01 2011-01-04 Merial Limited Recombinant vaccine against bluetongue virus
JP5771605B2 (ja) * 2009-05-22 2015-09-02 ジェノセア バイオサイエンシーズ, インコーポレイテッド 単純ヘルペスウイルス2型に対するワクチン:免疫応答を誘発する組成物および方法
KR20130118890A (ko) * 2010-11-19 2013-10-30 베이징 카윈 테크놀로지 쉐어-홀딩 컴퍼니 리미티드 B형 간염의 예방 및 치료를 위한 dna 백신 조성물
CN112034169A (zh) * 2020-08-27 2020-12-04 华威特(江苏)生物制药有限公司 用于检测牛病毒性腹泻病毒1型的直接免疫荧光试剂及其试剂盒

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994001133A1 (en) * 1992-07-08 1994-01-20 Schering Corporation Use of gm-csf as a vaccine adjuvant
EP1624068A1 (en) * 1993-06-01 2006-02-08 Life Technologies Inc. Genetic immunization with cationic lipids
US5658785A (en) * 1994-06-06 1997-08-19 Children's Hospital, Inc. Adeno-associated virus materials and methods
WO1996007739A2 (en) * 1994-09-09 1996-03-14 Neurocrine Biosciences, Incorporated Interleukin-1 type 3 receptors
US5736524A (en) * 1994-11-14 1998-04-07 Merck & Co.,. Inc. Polynucleotide tuberculosis vaccine
US5719131A (en) * 1994-12-09 1998-02-17 Genzyme Corporation Cationic amphiphiles containing dialkylamine lipophilic groups for intracellular delivery of therapeutic molecules
CA2214029A1 (en) * 1995-04-25 1996-10-31 Magda Marquet Single-vial formulations of dna/lipid complexes
AU5799996A (en) * 1995-05-26 1996-12-11 Cell Genesys, Inc. Delivery vehicles comprising stable lipid/nucleic acid compl exes
FR2751228B1 (fr) * 1996-07-19 1998-11-20 Rhone Merieux Vaccin polynucleotidique bovin pour voie intradermique
FR2751229B1 (fr) * 1996-07-19 1998-11-27 Rhone Merieux Formule de vaccin polynucleotidique notamment contre la pathologie respiratoire des bovins
FR2751224B1 (fr) * 1996-07-19 1998-11-20 Rhone Merieux Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs
AU1987197A (en) * 1997-03-10 1998-09-29 Heather Lynn Davis Gene delivery to mucosal epithelium for immunization or therapeutic purpose
AUPO856097A0 (en) * 1997-08-14 1997-09-04 Commonwealth Scientific And Industrial Research Organisation Vector
US6943152B1 (en) * 1999-06-10 2005-09-13 Merial DNA vaccine-PCV
PL210451B1 (pl) * 1999-06-10 2012-01-31 Merial Sas Szczepionka DNA przeciwko wirusowi nosówki psów (CDV)

Also Published As

Publication number Publication date
EP1248650A2 (fr) 2002-10-16
PL209304B1 (pl) 2011-08-31
JP2004500375A (ja) 2004-01-08
ES2277913T3 (es) 2007-08-01
HUP0203974A3 (en) 2004-07-28
DE60124862D1 (de) 2007-01-11
CY1107627T1 (el) 2013-04-18
CA2398229A1 (en) 2001-07-26
WO2001052888A2 (fr) 2001-07-26
WO2001052888A3 (fr) 2001-12-20
NZ520270A (en) 2004-08-27
CN1404398B (zh) 2012-05-02
PT1248650E (pt) 2007-02-28
DK1248650T3 (da) 2007-04-16
ZA200205698B (en) 2003-09-29
CN101554480A (zh) 2009-10-14
CA2398229C (en) 2012-05-15
PL356554A1 (en) 2004-06-28
AU783865B2 (en) 2005-12-15
AR027926A1 (es) 2003-04-16
HU229597B1 (en) 2014-02-28
CN1404398A (zh) 2003-03-19
FR2804028A1 (fr) 2001-07-27
BRPI0107767B1 (pt) 2017-10-24
EP1248650B1 (fr) 2006-11-29
DE60124862T2 (de) 2007-07-05
KR100820893B1 (ko) 2008-04-10
ATE346611T1 (de) 2006-12-15
AU3556601A (en) 2001-07-31
MXPA02007110A (es) 2003-01-28
FR2804028B1 (fr) 2004-06-04
BR0107767A (pt) 2002-11-12
KR20020084093A (ko) 2002-11-04

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