HUP0203974A2 - Javított DNS-oltóanyagok háziállatokhoz - Google Patents
Javított DNS-oltóanyagok háziállatokhozInfo
- Publication number
- HUP0203974A2 HUP0203974A2 HU0203974A HUP0203974A HUP0203974A2 HU P0203974 A2 HUP0203974 A2 HU P0203974A2 HU 0203974 A HU0203974 A HU 0203974A HU P0203974 A HUP0203974 A HU P0203974A HU P0203974 A2 HUP0203974 A2 HU P0203974A2
- Authority
- HU
- Hungary
- Prior art keywords
- production
- pathogen
- lipid
- dna vaccines
- carbon atoms
- Prior art date
Links
- 241001465754 Metazoa Species 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000002632 lipids Chemical class 0.000 abstract 2
- 244000052769 pathogen Species 0.000 abstract 2
- 230000001717 pathogenic effect Effects 0.000 abstract 2
- WALUVDCNGPQPOD-UHFFFAOYSA-M 2,3-di(tetradecoxy)propyl-(2-hydroxyethyl)-dimethylazanium;bromide Chemical compound [Br-].CCCCCCCCCCCCCCOCC(C[N+](C)(C)CCO)OCCCCCCCCCCCCCC WALUVDCNGPQPOD-UHFFFAOYSA-M 0.000 abstract 1
- 241000283690 Bos taurus Species 0.000 abstract 1
- 108010041986 DNA Vaccines Proteins 0.000 abstract 1
- 229940021995 DNA vaccine Drugs 0.000 abstract 1
- 241000282887 Suidae Species 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- -1 cationic quaternary ammonium salt Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 239000013612 plasmid Substances 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Dermatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
A találmány tárgyát képezi DNS-oltóanyag egy háziállatokat, különösenszarvasmarhákat és sertéseket fertőző kórokozó ellen, amely az adottállatfaj egy kórokozójának egy immunogénjét kódolónukleotidszekvenciát tartalmazó plazmidot tartalmaz olyan módon, amelylehetővé teszi a szekvencia in vivo expresszióját, továbbá (I)általános képletű, kvaterner ammóniumsót tartalmazó kationos lipidettartalmaz, ahol a képletben R1 jelentése telített vagy telítetlen,egyenesláncú 12-18 szénatomszámú alifás csoport, R2 egy másik, 2-3szénatomszámú alifás csoport, X jelentése pedig hidroxil- vagyaminocsoport, ez a lipid pedig előnyösen a DMRIE. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0000798A FR2804028B1 (fr) | 2000-01-21 | 2000-01-21 | Vaccins adn ameliores pour animaux de rente |
PCT/FR2001/000187 WO2001052888A2 (fr) | 2000-01-21 | 2001-01-19 | Vaccins adn ameliores pour animaux de rente |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP0203974A2 true HUP0203974A2 (hu) | 2003-03-28 |
HUP0203974A3 HUP0203974A3 (en) | 2004-07-28 |
HU229597B1 HU229597B1 (en) | 2014-02-28 |
Family
ID=8846183
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0203974A HU229597B1 (en) | 2000-01-21 | 2001-01-19 | Improved dna vaccines for production-type animals |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP1248650B1 (hu) |
JP (1) | JP2004500375A (hu) |
KR (1) | KR100820893B1 (hu) |
CN (2) | CN1404398B (hu) |
AR (1) | AR027926A1 (hu) |
AT (1) | ATE346611T1 (hu) |
AU (1) | AU783865B2 (hu) |
BR (2) | BRPI0107767B1 (hu) |
CA (1) | CA2398229C (hu) |
CY (1) | CY1107627T1 (hu) |
DE (1) | DE60124862T2 (hu) |
DK (1) | DK1248650T3 (hu) |
ES (1) | ES2277913T3 (hu) |
FR (1) | FR2804028B1 (hu) |
HU (1) | HU229597B1 (hu) |
MX (1) | MXPA02007110A (hu) |
NZ (1) | NZ520270A (hu) |
PL (1) | PL209304B1 (hu) |
PT (1) | PT1248650E (hu) |
WO (1) | WO2001052888A2 (hu) |
ZA (1) | ZA200205698B (hu) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6852705B2 (en) | 2000-01-21 | 2005-02-08 | Merial | DNA vaccines for farm animals, in particular bovines and porcines |
US7078388B2 (en) | 2000-01-21 | 2006-07-18 | Merial | DNA vaccines for farm animals, in particular bovines and porcines |
EP1587816B1 (en) | 2002-12-23 | 2010-06-16 | Vical Incorporated | Codon-optimized polynucleotide-based vaccines against human cytomegalovirus infection |
EP1594537B1 (en) * | 2003-02-19 | 2012-10-24 | Merial | Vaccination or immunization using a prime-boost regimen against brsv, bhv-1, bvdv, bpi-3 |
ES2417019T3 (es) | 2003-11-13 | 2013-08-05 | University Of Georgia Research Foundation, Inc. | Procedimiento de caracterización del virus de la enfermedad de la bursitis infecciosa |
CU23544A1 (es) | 2006-02-28 | 2010-06-17 | Ct Ingenieria Genetica Biotech | Antígenos vacunales quiméricos contra el virus de la peste porcina clásica |
US7862821B2 (en) | 2006-06-01 | 2011-01-04 | Merial Limited | Recombinant vaccine against bluetongue virus |
JP5771605B2 (ja) * | 2009-05-22 | 2015-09-02 | ジェノセア バイオサイエンシーズ, インコーポレイテッド | 単純ヘルペスウイルス2型に対するワクチン:免疫応答を誘発する組成物および方法 |
KR20130118890A (ko) * | 2010-11-19 | 2013-10-30 | 베이징 카윈 테크놀로지 쉐어-홀딩 컴퍼니 리미티드 | B형 간염의 예방 및 치료를 위한 dna 백신 조성물 |
CN112034169A (zh) * | 2020-08-27 | 2020-12-04 | 华威特(江苏)生物制药有限公司 | 用于检测牛病毒性腹泻病毒1型的直接免疫荧光试剂及其试剂盒 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994001133A1 (en) * | 1992-07-08 | 1994-01-20 | Schering Corporation | Use of gm-csf as a vaccine adjuvant |
EP1624068A1 (en) * | 1993-06-01 | 2006-02-08 | Life Technologies Inc. | Genetic immunization with cationic lipids |
US5658785A (en) * | 1994-06-06 | 1997-08-19 | Children's Hospital, Inc. | Adeno-associated virus materials and methods |
WO1996007739A2 (en) * | 1994-09-09 | 1996-03-14 | Neurocrine Biosciences, Incorporated | Interleukin-1 type 3 receptors |
US5736524A (en) * | 1994-11-14 | 1998-04-07 | Merck & Co.,. Inc. | Polynucleotide tuberculosis vaccine |
US5719131A (en) * | 1994-12-09 | 1998-02-17 | Genzyme Corporation | Cationic amphiphiles containing dialkylamine lipophilic groups for intracellular delivery of therapeutic molecules |
CA2214029A1 (en) * | 1995-04-25 | 1996-10-31 | Magda Marquet | Single-vial formulations of dna/lipid complexes |
AU5799996A (en) * | 1995-05-26 | 1996-12-11 | Cell Genesys, Inc. | Delivery vehicles comprising stable lipid/nucleic acid compl exes |
FR2751228B1 (fr) * | 1996-07-19 | 1998-11-20 | Rhone Merieux | Vaccin polynucleotidique bovin pour voie intradermique |
FR2751229B1 (fr) * | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique notamment contre la pathologie respiratoire des bovins |
FR2751224B1 (fr) * | 1996-07-19 | 1998-11-20 | Rhone Merieux | Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs |
AU1987197A (en) * | 1997-03-10 | 1998-09-29 | Heather Lynn Davis | Gene delivery to mucosal epithelium for immunization or therapeutic purpose |
AUPO856097A0 (en) * | 1997-08-14 | 1997-09-04 | Commonwealth Scientific And Industrial Research Organisation | Vector |
US6943152B1 (en) * | 1999-06-10 | 2005-09-13 | Merial | DNA vaccine-PCV |
PL210451B1 (pl) * | 1999-06-10 | 2012-01-31 | Merial Sas | Szczepionka DNA przeciwko wirusowi nosówki psów (CDV) |
-
2000
- 2000-01-21 FR FR0000798A patent/FR2804028B1/fr not_active Expired - Lifetime
-
2001
- 2001-01-19 AT AT01907651T patent/ATE346611T1/de active
- 2001-01-19 CN CN018054072A patent/CN1404398B/zh not_active Expired - Lifetime
- 2001-01-19 NZ NZ520270A patent/NZ520270A/en not_active IP Right Cessation
- 2001-01-19 EP EP01907651A patent/EP1248650B1/fr not_active Expired - Lifetime
- 2001-01-19 PL PL356554A patent/PL209304B1/pl unknown
- 2001-01-19 BR BRPI0107767-8A patent/BRPI0107767B1/pt unknown
- 2001-01-19 WO PCT/FR2001/000187 patent/WO2001052888A2/fr active IP Right Grant
- 2001-01-19 DE DE60124862T patent/DE60124862T2/de not_active Expired - Lifetime
- 2001-01-19 BR BR0107767-8A patent/BR0107767A/pt not_active IP Right Cessation
- 2001-01-19 ES ES01907651T patent/ES2277913T3/es not_active Expired - Lifetime
- 2001-01-19 CN CNA2008101667835A patent/CN101554480A/zh active Pending
- 2001-01-19 MX MXPA02007110A patent/MXPA02007110A/es active IP Right Grant
- 2001-01-19 DK DK01907651T patent/DK1248650T3/da active
- 2001-01-19 PT PT01907651T patent/PT1248650E/pt unknown
- 2001-01-19 AU AU35566/01A patent/AU783865B2/en not_active Expired
- 2001-01-19 KR KR1020027009300A patent/KR100820893B1/ko active IP Right Grant
- 2001-01-19 JP JP2001552935A patent/JP2004500375A/ja active Pending
- 2001-01-19 CA CA2398229A patent/CA2398229C/en not_active Expired - Lifetime
- 2001-01-19 HU HU0203974A patent/HU229597B1/hu unknown
- 2001-01-22 AR ARP010100267A patent/AR027926A1/es not_active Application Discontinuation
-
2002
- 2002-07-17 ZA ZA200205698A patent/ZA200205698B/en unknown
-
2007
- 2007-02-14 CY CY20071100201T patent/CY1107627T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP1248650A2 (fr) | 2002-10-16 |
PL209304B1 (pl) | 2011-08-31 |
JP2004500375A (ja) | 2004-01-08 |
ES2277913T3 (es) | 2007-08-01 |
HUP0203974A3 (en) | 2004-07-28 |
DE60124862D1 (de) | 2007-01-11 |
CY1107627T1 (el) | 2013-04-18 |
CA2398229A1 (en) | 2001-07-26 |
WO2001052888A2 (fr) | 2001-07-26 |
WO2001052888A3 (fr) | 2001-12-20 |
NZ520270A (en) | 2004-08-27 |
CN1404398B (zh) | 2012-05-02 |
PT1248650E (pt) | 2007-02-28 |
DK1248650T3 (da) | 2007-04-16 |
ZA200205698B (en) | 2003-09-29 |
CN101554480A (zh) | 2009-10-14 |
CA2398229C (en) | 2012-05-15 |
PL356554A1 (en) | 2004-06-28 |
AU783865B2 (en) | 2005-12-15 |
AR027926A1 (es) | 2003-04-16 |
HU229597B1 (en) | 2014-02-28 |
CN1404398A (zh) | 2003-03-19 |
FR2804028A1 (fr) | 2001-07-27 |
BRPI0107767B1 (pt) | 2017-10-24 |
EP1248650B1 (fr) | 2006-11-29 |
DE60124862T2 (de) | 2007-07-05 |
KR100820893B1 (ko) | 2008-04-10 |
ATE346611T1 (de) | 2006-12-15 |
AU3556601A (en) | 2001-07-31 |
MXPA02007110A (es) | 2003-01-28 |
FR2804028B1 (fr) | 2004-06-04 |
BR0107767A (pt) | 2002-11-12 |
KR20020084093A (ko) | 2002-11-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUP0203974A2 (hu) | Javított DNS-oltóanyagok háziállatokhoz | |
MXPA03011815A (es) | Vacuna de micoplasma bovis y metodos para reducir la neumonia en animales. | |
US2798241A (en) | Magnet carrying toothbrush | |
AR024334A1 (es) | Vacunas adn para animales de compania y de deporte | |
YU102203A (sh) | Vakcinacija sa jednokratnom dozom mycoplasma hyopneumoniae | |
ATE397942T1 (de) | Adjuvanszusammensetzungen zur erhöhung der immunantwort bezüglich polynukleotid-basierenden impfstoffen | |
CY1109463T1 (el) | Πεπτιδια kdr και εμβολια που τα περιλαμβανουν | |
MXPA03011924A (es) | Vacuna de micoplasma hyopneumoniae y metodos para reducir la neumonia por mycoplasma bovis en el ganado. | |
HUP0401868A2 (hu) | Rekombináns vakcina West Nile vírus ellen | |
DK0775746T3 (da) | Vaccine mod fjerkræcoccidiose | |
PT653489E (pt) | Vacina contra a coccidiose em aves domesticas | |
FR2828405B1 (fr) | Vaccin anti-coronavirus | |
DK0709460T3 (da) | Fjerkrævaccine imod coccidiosis | |
TW200801034A (en) | Novel sea lice vaccine | |
FR2724385B1 (fr) | Vaccin de la peritonite infectieuse feline. | |
DE60126490D1 (de) | Adjuvanszusammensetzung enthaltend fha oder ein fha-fragment in freier form | |
BR0002602A (pt) | Vacina viva atenuada, uso de uma bactéria viva atenuada, e, processo para a preparação de uma vacina | |
CY1107374T1 (el) | Εμβολιο ιχθυος εναντι της piscirickettsia salmonis | |
HUP9802974A1 (hu) | Fertőző bursitis elleni DNS-vakcina | |
HUP0103871A2 (hu) | Rekombináns CELO-vírus és CELO vírus DNS | |
BR9805135A (pt) | ilato sintase de neospora. | |
BR0110791A (pt) | Composição, métodos para induzir uma resposta imune em um indivìduo contra um imunogene, para modular o sistema imune de um indivìduo e para imunizar um indivìduo contra um patógeno, vacina recombinante, e patógeno atenuado vivo | |
TH62970A (th) | วัคซีนไวรัสโรคเบอร์ซาอักเสบติดต่อชนิดบรอดสเปคตรัม (broad spectrum) | |
TH55549B (th) | วัคซีนดีเอนเอที่ได้ปรับปรุงสำหรับสัตว์ในฟาร์ม | |
Thomson et al. | Foot and Mouth Disease in Southern Africa: Re-evaluation of the approach to control |