CY1107139T1 - Μεθοδος παρασκευης πυρρολιδινοξιμων - Google Patents

Μεθοδος παρασκευης πυρρολιδινοξιμων

Info

Publication number
CY1107139T1
CY1107139T1 CY20081100051T CY081100051T CY1107139T1 CY 1107139 T1 CY1107139 T1 CY 1107139T1 CY 20081100051 T CY20081100051 T CY 20081100051T CY 081100051 T CY081100051 T CY 081100051T CY 1107139 T1 CY1107139 T1 CY 1107139T1
Authority
CY
Cyprus
Prior art keywords
pyrolidinoximum
preparation
formula
dysmenorrhea
prevention
Prior art date
Application number
CY20081100051T
Other languages
English (en)
Inventor
William Nadler
Doris Pupowicz
Original Assignee
Laboratoires Serono Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Serono Sa filed Critical Laboratoires Serono Sa
Publication of CY1107139T1 publication Critical patent/CY1107139T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Η παρούσα ευρεσιτεχνία αναφέρεται σε νέα σύνθεση για την παρασκευή πυρρολιδινοξιμών του τύπου (Ι). Οι ενώσεις του γενικού τύπου (Ι) είναι χρήσιμες στην θεραπευτική και/ή την πρόληψη του πρόωρου κοιλοπονήματος, του πρόωρου τοκετού και της δυσμηνόρροιας.
CY20081100051T 2004-02-26 2008-01-14 Μεθοδος παρασκευης πυρρολιδινοξιμων CY1107139T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04100773 2004-02-26
EP05708062A EP1725526B1 (en) 2004-02-26 2005-02-28 Method for preparing pyrrolidine oximes

Publications (1)

Publication Number Publication Date
CY1107139T1 true CY1107139T1 (el) 2012-10-24

Family

ID=34896105

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20081100051T CY1107139T1 (el) 2004-02-26 2008-01-14 Μεθοδος παρασκευης πυρρολιδινοξιμων

Country Status (21)

Country Link
US (1) US20070197794A1 (el)
EP (1) EP1725526B1 (el)
JP (1) JP2007524702A (el)
KR (1) KR20060124775A (el)
CN (1) CN1946686A (el)
AT (1) ATE380792T1 (el)
AU (1) AU2005217153A1 (el)
BR (1) BRPI0508059A (el)
CA (1) CA2554767A1 (el)
CY (1) CY1107139T1 (el)
DE (1) DE602005003803T2 (el)
DK (1) DK1725526T3 (el)
EA (1) EA011026B1 (el)
ES (1) ES2296137T3 (el)
IL (1) IL177388A0 (el)
NO (1) NO20064352L (el)
PL (1) PL1725526T3 (el)
PT (1) PT1725526E (el)
SI (1) SI1725526T1 (el)
UA (1) UA86226C2 (el)
WO (1) WO2005082848A2 (el)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2845850A1 (en) 2013-09-10 2015-03-11 ObsEva S.A. Pyrrolidine derivatives as oxytocin/vasopressin V1a receptors antagonists
EP2886107A1 (en) 2013-12-17 2015-06-24 ObsEva S.A. Oral formulations of pyrrolydine derivatives
ES2774789T3 (es) 2014-07-02 2020-07-22 ObsEva SA O-Metiloxima de (3Z,5S)-5-(hidroximetil)-1-[(2'-metil-1,1'-bifenil-4-il)carbonil]pirrolidin-3-ona cristalina útil en métodos de tratamiento de estados relacionados con la actividad del OT-R
WO2021165927A1 (en) * 2020-02-21 2021-08-26 Wockhardt Bio Ag 2-cyanopyrroldines, -piperidines or -dazepines as hyperglycemic agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6329418B1 (en) * 1998-04-14 2001-12-11 The Procter & Gamble Company Substituted pyrrolidine hydroxamate metalloprotease inhibitors
WO2001072705A1 (en) * 2000-03-27 2001-10-04 Applied Research Systems Ars Holding N.V. Pharmaceutically active pyrrolidine derivatives as bax inhibitors
BR0211030A (pt) * 2001-06-18 2004-06-22 Applied Research Systems Derivado de pirrolidina oxadiazole, uso de um derivado de pirrolidina oxadiazole, composição farmacêutica contendo pelo menos um derivado de pirrolidina oxadiazole, método para preparação de um composto de pirrolidina oxadiazole

Also Published As

Publication number Publication date
SI1725526T1 (sl) 2008-04-30
PL1725526T3 (pl) 2008-03-31
KR20060124775A (ko) 2006-12-05
PT1725526E (pt) 2007-12-27
ES2296137T3 (es) 2008-04-16
ATE380792T1 (de) 2007-12-15
EP1725526A2 (en) 2006-11-29
DE602005003803T2 (de) 2008-12-24
IL177388A0 (en) 2006-12-10
NO20064352L (no) 2006-09-26
AU2005217153A1 (en) 2005-09-09
EA011026B1 (ru) 2008-12-30
DK1725526T3 (da) 2008-03-03
EA200601456A1 (ru) 2007-02-27
EP1725526B1 (en) 2007-12-12
WO2005082848A2 (en) 2005-09-09
UA86226C2 (en) 2009-04-10
BRPI0508059A (pt) 2007-07-17
WO2005082848A3 (en) 2005-12-01
JP2007524702A (ja) 2007-08-30
US20070197794A1 (en) 2007-08-23
CA2554767A1 (en) 2005-09-09
CN1946686A (zh) 2007-04-11
DE602005003803D1 (de) 2008-01-24

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