CU23236A1 - PROTEINA NMB0928 Y SU USO EN FORMULACIONES FARMACéUTICAS P - Google Patents
PROTEINA NMB0928 Y SU USO EN FORMULACIONES FARMACéUTICAS PInfo
- Publication number
- CU23236A1 CU23236A1 CU2002008620030286A CU20030286A CU23236A1 CU 23236 A1 CU23236 A1 CU 23236A1 CU 2002008620030286 A CU2002008620030286 A CU 2002008620030286A CU 20030286 A CU20030286 A CU 20030286A CU 23236 A1 CU23236 A1 CU 23236A1
- Authority
- CU
- Cuba
- Prior art keywords
- cea
- human
- formulations
- chain
- scfv
- Prior art date
Links
- 101100431363 Neisseria meningitidis serogroup B (strain MC58) NMB0928 gene Proteins 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 102100022019 Pregnancy-specific beta-1-glycoprotein 2 Human genes 0.000 abstract 4
- 238000009472 formulation Methods 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- 239000012634 fragment Substances 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 238000001727 in vivo Methods 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 210000001519 tissue Anatomy 0.000 abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 2
- 102000008394 Immunoglobulin Fragments Human genes 0.000 abstract 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 241000699670 Mus sp. Species 0.000 abstract 1
- 241000588650 Neisseria meningitidis Species 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 235000014633 carbohydrates Nutrition 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000002566 clonic effect Effects 0.000 abstract 1
- 238000010367 cloning Methods 0.000 abstract 1
- 230000009260 cross reactivity Effects 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 210000005260 human cell Anatomy 0.000 abstract 1
- 210000004408 hybridoma Anatomy 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 230000005847 immunogenicity Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 239000003550 marker Substances 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000004877 mucosa Anatomy 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 238000012163 sequencing technique Methods 0.000 abstract 1
- 238000001228 spectrum Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3007—Carcino-embryonic Antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/626—Diabody or triabody
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (16)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU2002008620030286A CU23236A1 (es) | 2003-12-03 | 2003-12-03 | PROTEINA NMB0928 Y SU USO EN FORMULACIONES FARMACéUTICAS P |
| ARP040104482A AR046937A1 (es) | 2003-12-03 | 2004-12-01 | Proteina nmb0928 y su uso en formulaciones farmaceuticas |
| CNB2004800358798A CN100549027C (zh) | 2003-12-03 | 2004-12-02 | Nmb0928蛋白及其在药物制剂中的用途 |
| AU2004294377A AU2004294377A1 (en) | 2003-12-03 | 2004-12-02 | Protein NMB0928 and use thereof in pharmaceutical formulations |
| CA002547537A CA2547537A1 (en) | 2003-12-03 | 2004-12-02 | Protein nmb0928 and use thereof in pharmaceutical formulations |
| KR1020067011597A KR20060124625A (ko) | 2003-12-03 | 2004-12-02 | 단백질 ｎｍｂ0928 및 약학적 제형에서의 이의 용도 |
| EP04802608A EP1693379B1 (en) | 2003-12-03 | 2004-12-02 | Protein nmb0928 and use thereof in pharmaceutical formulations |
| NZ547521A NZ547521A (en) | 2003-12-03 | 2004-12-02 | Protein NMB0928 and use thereof in pharmaceutical formulations |
| DE602004025377T DE602004025377D1 (de) | 2003-12-03 | 2004-12-02 | Nmb0928-protein und dessen verwendung in pharmazeutischen formulierungen |
| BRPI0417334-1A BRPI0417334A (pt) | 2003-12-03 | 2004-12-02 | proteìna nmb0928 e uso da mesma em formulações farmacêuticas |
| PCT/CU2004/000016 WO2005054282A1 (es) | 2003-12-03 | 2004-12-02 | Proteína nmb0928 y su uso en formulaciones farmaceuticas |
| US10/580,888 US20070128230A1 (en) | 2003-12-03 | 2004-12-02 | Protein nmb0928 and use thereof in pharmaceutical formulations |
| RU2006123414/13A RU2335505C2 (ru) | 2003-12-03 | 2004-12-02 | Белок nmb0928 и его применение в фармацевтических композициях |
| AT04802608T ATE456573T1 (de) | 2003-12-03 | 2004-12-02 | Nmb0928-protein und dessen verwendung in pharmazeutischen formulierungen |
| ZA200604492A ZA200604492B (en) | 2003-12-03 | 2006-06-01 | Protein NMB0928 and use thereof in pharmaceutical formulations |
| NO20063017A NO20063017L (no) | 2003-12-03 | 2006-06-28 | Protein NMB0928 og anvendelse derav i farmasoytiske formuleringer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU2002008620030286A CU23236A1 (es) | 2003-12-03 | 2003-12-03 | PROTEINA NMB0928 Y SU USO EN FORMULACIONES FARMACéUTICAS P |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CU23236A1 true CU23236A1 (es) | 2007-09-26 |
Family
ID=40091627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU2002008620030286A CU23236A1 (es) | 2003-12-03 | 2003-12-03 | PROTEINA NMB0928 Y SU USO EN FORMULACIONES FARMACéUTICAS P |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20070128230A1 (no) |
| EP (1) | EP1693379B1 (no) |
| KR (1) | KR20060124625A (no) |
| CN (1) | CN100549027C (no) |
| AR (1) | AR046937A1 (no) |
| AT (1) | ATE456573T1 (no) |
| AU (1) | AU2004294377A1 (no) |
| BR (1) | BRPI0417334A (no) |
| CA (1) | CA2547537A1 (no) |
| CU (1) | CU23236A1 (no) |
| DE (1) | DE602004025377D1 (no) |
| NO (1) | NO20063017L (no) |
| NZ (1) | NZ547521A (no) |
| RU (1) | RU2335505C2 (no) |
| WO (1) | WO2005054282A1 (no) |
| ZA (1) | ZA200604492B (no) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CU23549A1 (es) * | 2005-12-29 | 2010-07-20 | Ct Ingenieria Genetica Biotech | Composiciones farmacéuticas que contienen la proteína nma0939 |
| CU23575A1 (es) * | 2006-03-31 | 2010-09-30 | Ct Ingenieria Genetica Biotech | Composición farmacéutica que comprende la proteína nmb0606 |
| CU23572A1 (es) * | 2006-03-31 | 2010-09-30 | Ct Ingenieria Genetica Biotech | Composición farmacéutica que comprende la proteína nmb0938 |
| MX2019002489A (es) | 2016-09-02 | 2019-10-21 | Sanofi Pasteur Inc | Vacuna contra neisseria meningitidis. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4219821A1 (de) * | 1992-06-17 | 1993-12-23 | Boehringer Mannheim Gmbh | Spezifischer Nachweis von Neisseria Gonorrhoeae |
| CU22559A1 (es) * | 1996-01-17 | 1999-05-03 | Ct Ingenieria Genetica Biotech | Sistema de expresión de antígenos heterologos en e. coli como proteínas de fusión |
| BR9910089A (pt) * | 1998-05-01 | 2004-06-08 | Chiron Corp | Composições e antìgenos de neisseria meningitidis |
| EP2275552B1 (en) * | 1999-10-29 | 2015-09-09 | GlaxoSmithKline Biologicals SA | Neisserial antigenic peptides |
| GB9928196D0 (en) * | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
-
2003
- 2003-12-03 CU CU2002008620030286A patent/CU23236A1/es unknown
-
2004
- 2004-12-01 AR ARP040104482A patent/AR046937A1/es unknown
- 2004-12-02 BR BRPI0417334-1A patent/BRPI0417334A/pt not_active IP Right Cessation
- 2004-12-02 EP EP04802608A patent/EP1693379B1/en active Active
- 2004-12-02 CN CNB2004800358798A patent/CN100549027C/zh not_active Expired - Fee Related
- 2004-12-02 DE DE602004025377T patent/DE602004025377D1/de active Active
- 2004-12-02 US US10/580,888 patent/US20070128230A1/en not_active Abandoned
- 2004-12-02 KR KR1020067011597A patent/KR20060124625A/ko not_active Application Discontinuation
- 2004-12-02 RU RU2006123414/13A patent/RU2335505C2/ru not_active IP Right Cessation
- 2004-12-02 CA CA002547537A patent/CA2547537A1/en not_active Abandoned
- 2004-12-02 WO PCT/CU2004/000016 patent/WO2005054282A1/es active Application Filing
- 2004-12-02 NZ NZ547521A patent/NZ547521A/xx unknown
- 2004-12-02 AU AU2004294377A patent/AU2004294377A1/en not_active Abandoned
- 2004-12-02 AT AT04802608T patent/ATE456573T1/de not_active IP Right Cessation
-
2006
- 2006-06-01 ZA ZA200604492A patent/ZA200604492B/en unknown
- 2006-06-28 NO NO20063017A patent/NO20063017L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE456573T1 (de) | 2010-02-15 |
| BRPI0417334A (pt) | 2007-03-27 |
| WO2005054282A1 (es) | 2005-06-16 |
| DE602004025377D1 (de) | 2010-03-18 |
| CA2547537A1 (en) | 2005-06-16 |
| CN1890261A (zh) | 2007-01-03 |
| CN100549027C (zh) | 2009-10-14 |
| RU2006123414A (ru) | 2008-01-10 |
| RU2335505C2 (ru) | 2008-10-10 |
| AR046937A1 (es) | 2006-01-04 |
| AU2004294377A1 (en) | 2005-06-16 |
| EP1693379B1 (en) | 2010-01-27 |
| KR20060124625A (ko) | 2006-12-05 |
| US20070128230A1 (en) | 2007-06-07 |
| NO20063017L (no) | 2006-09-01 |
| EP1693379A1 (en) | 2006-08-23 |
| NZ547521A (en) | 2009-07-31 |
| ZA200604492B (en) | 2007-05-30 |
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