CU20100143A7 - Hormonas de administración transdérmica que no necesitan potenciadores de penetración - Google Patents
Hormonas de administración transdérmica que no necesitan potenciadores de penetraciónInfo
- Publication number
- CU20100143A7 CU20100143A7 CU2010000143A CU20100143A CU20100143A7 CU 20100143 A7 CU20100143 A7 CU 20100143A7 CU 2010000143 A CU2010000143 A CU 2010000143A CU 20100143 A CU20100143 A CU 20100143A CU 20100143 A7 CU20100143 A7 CU 20100143A7
- Authority
- CU
- Cuba
- Prior art keywords
- hormones
- patch
- potentiators
- transdermal administration
- need
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Botany (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Reproductive Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Abstract
La invención se refiere a un parche que comprende una capa de droga con un bajo contenido de hormonas, como por ejemplo gestodeno, y opcionalmente un estrógeno (por ejemplo etinilestradiol). Al aplicar el parche a una mujer, se consiguen niveles en plasma de al menos 1,0 ng/ml de gestodeno en condiciones de estado estacionario sin necesidad de incorporar potenciadores de penetración ni mejoradores de permeación en la capa que contiene droga. También son satisfactorios los niveles en plasma de las hormonas que se consiguen durante todo un periodo de al menos una semana, haciendo que el parche se pueda aplicar para utilizarlo en anticoncepción femenina con el concepto de aplicar el parche una vez a la semana.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US52871803P | 2003-12-12 | 2003-12-12 | |
EP03078881 | 2003-12-12 | ||
PCT/IB2004/052752 WO2005058287A2 (en) | 2003-12-12 | 2004-12-10 | Transdermal delivery system of hormones without penetration enhancers |
Publications (2)
Publication Number | Publication Date |
---|---|
CU20100143A7 true CU20100143A7 (es) | 2011-10-31 |
CU23868B1 CU23868B1 (es) | 2013-03-27 |
Family
ID=34702342
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CU20100143A CU23868B1 (es) | 2003-12-12 | 2010-07-05 | Hormonas de administración transdérmica que no necesitan potenciadores de penetración |
Country Status (15)
Country | Link |
---|---|
JP (1) | JP4965263B2 (es) |
KR (1) | KR101168449B1 (es) |
CN (1) | CN1913878B (es) |
AU (1) | AU2004298930B2 (es) |
BR (1) | BRPI0417530B8 (es) |
CA (1) | CA2549916C (es) |
CU (1) | CU23868B1 (es) |
EA (1) | EA011160B1 (es) |
EC (1) | ECSP066694A (es) |
IL (1) | IL176112A (es) |
MX (1) | MXPA06006682A (es) |
NO (1) | NO341989B1 (es) |
NZ (1) | NZ548091A (es) |
WO (1) | WO2005058287A2 (es) |
ZA (1) | ZA200605713B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2515918C (en) | 2003-02-21 | 2010-11-16 | Schering Ag | Uv stable transdermal therapeutic plaster |
US8962013B2 (en) | 2005-05-02 | 2015-02-24 | Bayer Intellectual Property Gmbh | Multi-layered transdermal system with triazine UV absorber |
DE102005050729A1 (de) * | 2005-10-19 | 2007-04-26 | Schering Ag | Verfahren zur präventiven bedarfsweisen hormonalen Kontrazeption |
FR2900048B1 (fr) * | 2006-04-21 | 2012-11-16 | Oreal | Compositions comprenant un derive diphenyl-methane hydroxyle |
DK2613772T3 (en) | 2010-09-06 | 2017-03-06 | Bayer Ip Gmbh | TRANSDERMAL LOW DOSAGE PATTERNS WITH HIGH PHARMACEUTICAL RELEASE |
AU2015203180B2 (en) * | 2010-09-06 | 2016-06-30 | Bayer Intellectual Property Gmbh | Transdermal therapeutic systems with crystallization-inhibiting protective film (release liner) |
DE102010040299A1 (de) * | 2010-09-06 | 2012-03-08 | Bayer Schering Pharma Aktiengesellschaft | Transdermale therapeutische Systeme mit kristallisationsinhibierender Schutzfolie (Release Liner) |
JP6345120B2 (ja) * | 2012-01-27 | 2018-06-20 | アジル・セラピューティクス・インコーポレイテッドAgile Therapeutics, Inc. | 経皮ホルモン送達 |
BR112017024783A2 (pt) * | 2015-05-18 | 2018-08-07 | Agile Therapeutics Inc | composições contraceptivas e métodos para eficácia melhorada e modulação dos efeitos colaterais |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3238389B2 (ja) * | 1988-10-27 | 2001-12-10 | シエーリング アクチエンゲゼルシヤフト | ゲストデン含有の経皮適用のための薬剤 |
MX9101787A (es) * | 1990-10-29 | 1992-06-05 | Alza Corp | Formulaciones,metodos y dispositivos anticonceptivos transdermicos |
US5512292A (en) * | 1990-10-29 | 1996-04-30 | Alza Corporation | Transdermal contraceptive formulations methods and devices |
DE4329242A1 (de) * | 1993-08-26 | 1995-03-02 | Schering Ag | Mittel zur transdermalen Applikation enthaltend Gestodenester |
DE4405898A1 (de) * | 1994-02-18 | 1995-08-24 | Schering Ag | Transdermale therapeutische Systeme enthaltend Sexualsteroide |
EP0787488A4 (en) * | 1994-11-18 | 1998-06-03 | Hisamitsu Pharmaceutical Co | TRANSDERMAL ABSORBABLE PLASTER |
IL122432A (en) * | 1995-06-07 | 2000-07-16 | Cygnus Therapeutic Systems | Transdermal patch for preventing ovulation |
JP4346696B2 (ja) * | 1996-05-28 | 2009-10-21 | 久光製薬株式会社 | 経皮治療用装置 |
JP4167750B2 (ja) * | 1997-04-16 | 2008-10-22 | 久光製薬株式会社 | 経皮吸収用基剤及び該基剤を含有する経皮吸収製剤 |
JP4399044B2 (ja) * | 1998-10-14 | 2010-01-13 | 久光製薬株式会社 | 吸収促進剤及び該吸収促進剤を有してなる経皮吸収製剤 |
DE19906152B4 (de) * | 1999-02-10 | 2005-02-10 | Jenapharm Gmbh & Co. Kg | Wirkstoffhaltige Laminate für Transdermalsysteme |
EP1197212A4 (en) * | 1999-07-01 | 2004-06-02 | Hisamitsu Pharmaceutical Co | ADHESIVE COMPOSITION FOR PERCUTANE ABSORPTION |
DE10053375C1 (de) * | 2000-10-27 | 2002-01-24 | Lohmann Therapie Syst Lts | Transdermale therapeutische Systeme mit lichtempfindlichen Wirkstoffen |
WO2002045701A2 (en) * | 2000-12-05 | 2002-06-13 | Noven Pharmaceuticals, Inc. | Crystallization inhibition of drugs in transdermal drug delivery systems |
-
2004
- 2004-12-10 CN CN2004800413210A patent/CN1913878B/zh active Active
- 2004-12-10 MX MXPA06006682A patent/MXPA06006682A/es active IP Right Grant
- 2004-12-10 JP JP2006543709A patent/JP4965263B2/ja active Active
- 2004-12-10 KR KR1020067013923A patent/KR101168449B1/ko active IP Right Grant
- 2004-12-10 AU AU2004298930A patent/AU2004298930B2/en not_active Ceased
- 2004-12-10 NZ NZ548091A patent/NZ548091A/en not_active IP Right Cessation
- 2004-12-10 CA CA2549916A patent/CA2549916C/en not_active Expired - Fee Related
- 2004-12-10 EA EA200601089A patent/EA011160B1/ru not_active IP Right Cessation
- 2004-12-10 BR BRPI0417530A patent/BRPI0417530B8/pt not_active IP Right Cessation
- 2004-12-10 WO PCT/IB2004/052752 patent/WO2005058287A2/en active Application Filing
-
2006
- 2006-06-05 IL IL176112A patent/IL176112A/en active IP Right Grant
- 2006-06-06 NO NO20062594A patent/NO341989B1/no not_active IP Right Cessation
- 2006-07-11 ZA ZA2006/05713A patent/ZA200605713B/en unknown
- 2006-07-11 EC EC2006006694A patent/ECSP066694A/es unknown
-
2010
- 2010-07-05 CU CU20100143A patent/CU23868B1/es active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
BRPI0417530A (pt) | 2007-03-13 |
CU23868B1 (es) | 2013-03-27 |
WO2005058287A3 (en) | 2006-03-02 |
ECSP066694A (es) | 2006-10-31 |
IL176112A0 (en) | 2006-10-05 |
JP2007513938A (ja) | 2007-05-31 |
MXPA06006682A (es) | 2006-08-11 |
AU2004298930B2 (en) | 2009-11-26 |
JP4965263B2 (ja) | 2012-07-04 |
IL176112A (en) | 2011-02-28 |
AU2004298930A1 (en) | 2005-06-30 |
CN1913878B (zh) | 2010-05-26 |
ZA200605713B (en) | 2008-01-08 |
NO341989B1 (no) | 2018-03-12 |
BRPI0417530B1 (pt) | 2018-01-23 |
KR101168449B1 (ko) | 2012-07-25 |
NZ548091A (en) | 2009-12-24 |
KR20060128910A (ko) | 2006-12-14 |
CA2549916A1 (en) | 2005-06-30 |
CN1913878A (zh) | 2007-02-14 |
WO2005058287A2 (en) | 2005-06-30 |
NO20062594L (no) | 2006-07-10 |
EA200601089A1 (ru) | 2006-12-29 |
CA2549916C (en) | 2013-09-17 |
BRPI0417530B8 (pt) | 2021-05-25 |
EA011160B1 (ru) | 2009-02-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant of patent |