ECSP066694A - Hormonas de administración transdérmica que no necesitan potenciadores de penetración - Google Patents
Hormonas de administración transdérmica que no necesitan potenciadores de penetraciónInfo
- Publication number
- ECSP066694A ECSP066694A EC2006006694A ECSP066694A ECSP066694A EC SP066694 A ECSP066694 A EC SP066694A EC 2006006694 A EC2006006694 A EC 2006006694A EC SP066694 A ECSP066694 A EC SP066694A EC SP066694 A ECSP066694 A EC SP066694A
- Authority
- EC
- Ecuador
- Prior art keywords
- hormones
- patch
- potentiators
- transdermal administration
- need
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
Abstract
La presente invención se refiere a un parche que comprende una capa de droga con un bajo contenido de hormonas, como por ejemplo gestodeno, y opcionalmente un estrógeno (por ejemplo etinilestradiol). Al aplicar el parche a una mujer, se consiguen niveles en plasma de al menos 1,0 ng/ml de gestodeno en condiciones de estado estacionario sin necesidad de incorporar potenciadores de penetración ni mejoradores de permeación en la capa que contiene droga. También son satisfactorios los niveles en plasma de las hormonas que se consiguen durante todo un período de al menos 1 semana, haciendo que el parche se pueda aplicar para utilizarlo en anticoncepción femenina con el concepto de aplicar el parche una vez a la semana
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US52871803P | 2003-12-12 | 2003-12-12 | |
EP03078881 | 2003-12-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP066694A true ECSP066694A (es) | 2006-10-31 |
Family
ID=34702342
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2006006694A ECSP066694A (es) | 2003-12-12 | 2006-07-11 | Hormonas de administración transdérmica que no necesitan potenciadores de penetración |
Country Status (15)
Country | Link |
---|---|
JP (1) | JP4965263B2 (es) |
KR (1) | KR101168449B1 (es) |
CN (1) | CN1913878B (es) |
AU (1) | AU2004298930B2 (es) |
BR (1) | BRPI0417530B8 (es) |
CA (1) | CA2549916C (es) |
CU (1) | CU23868B1 (es) |
EA (1) | EA011160B1 (es) |
EC (1) | ECSP066694A (es) |
IL (1) | IL176112A (es) |
MX (1) | MXPA06006682A (es) |
NO (1) | NO341989B1 (es) |
NZ (1) | NZ548091A (es) |
WO (1) | WO2005058287A2 (es) |
ZA (1) | ZA200605713B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE333271T1 (de) | 2003-02-21 | 2006-08-15 | Schering Ag | Uv-stabiles transdermales pflaster |
US8962013B2 (en) | 2005-05-02 | 2015-02-24 | Bayer Intellectual Property Gmbh | Multi-layered transdermal system with triazine UV absorber |
DE102005050729A1 (de) * | 2005-10-19 | 2007-04-26 | Schering Ag | Verfahren zur präventiven bedarfsweisen hormonalen Kontrazeption |
FR2900048B1 (fr) * | 2006-04-21 | 2012-11-16 | Oreal | Compositions comprenant un derive diphenyl-methane hydroxyle |
DE102010040299A1 (de) | 2010-09-06 | 2012-03-08 | Bayer Schering Pharma Aktiengesellschaft | Transdermale therapeutische Systeme mit kristallisationsinhibierender Schutzfolie (Release Liner) |
DK2613772T3 (en) | 2010-09-06 | 2017-03-06 | Bayer Ip Gmbh | TRANSDERMAL LOW DOSAGE PATTERNS WITH HIGH PHARMACEUTICAL RELEASE |
AU2015203180B2 (en) * | 2010-09-06 | 2016-06-30 | Bayer Intellectual Property Gmbh | Transdermal therapeutic systems with crystallization-inhibiting protective film (release liner) |
EP2806862A2 (en) * | 2012-01-27 | 2014-12-03 | Agile Therapeutics, Inc. | Transdermal hormone delivery |
US20180125860A1 (en) * | 2015-05-18 | 2018-05-10 | Agile Therapeutics, Inc. | Contraceptive Compositions and Methods for Improved Efficacy and Modulation of Side Effects |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990004397A1 (de) * | 1988-10-27 | 1990-05-03 | Schering Aktiengesellschaft Berlin Und Bergkamen | Mittel zur transdermalen applikation enthaltend gestoden |
US5512292A (en) * | 1990-10-29 | 1996-04-30 | Alza Corporation | Transdermal contraceptive formulations methods and devices |
WO1992007590A1 (en) * | 1990-10-29 | 1992-05-14 | Alza Corporation | Transdermal contraceptive formulations, methods and devices |
DE4329242A1 (de) * | 1993-08-26 | 1995-03-02 | Schering Ag | Mittel zur transdermalen Applikation enthaltend Gestodenester |
DE4405898A1 (de) * | 1994-02-18 | 1995-08-24 | Schering Ag | Transdermale therapeutische Systeme enthaltend Sexualsteroide |
AU692944B2 (en) * | 1994-11-18 | 1998-06-18 | Hisamitsu Pharmaceutical Co., Inc. | Percutaneously absorbable patch |
ES2190472T5 (es) * | 1995-06-07 | 2012-03-09 | Ortho-Mcneil Pharmaceutical, Inc. | Parche transdérmico para la administración de 17-deacetil norgestimato, en combinación con un estrógeno. |
JP4346696B2 (ja) * | 1996-05-28 | 2009-10-21 | 久光製薬株式会社 | 経皮治療用装置 |
JP4167750B2 (ja) * | 1997-04-16 | 2008-10-22 | 久光製薬株式会社 | 経皮吸収用基剤及び該基剤を含有する経皮吸収製剤 |
JP4399044B2 (ja) * | 1998-10-14 | 2010-01-13 | 久光製薬株式会社 | 吸収促進剤及び該吸収促進剤を有してなる経皮吸収製剤 |
DE19906152B4 (de) * | 1999-02-10 | 2005-02-10 | Jenapharm Gmbh & Co. Kg | Wirkstoffhaltige Laminate für Transdermalsysteme |
KR20010112479A (ko) * | 1999-07-01 | 2001-12-20 | 나까도미 히로다카 | 경피흡수 첩부제 |
DE10053375C1 (de) * | 2000-10-27 | 2002-01-24 | Lohmann Therapie Syst Lts | Transdermale therapeutische Systeme mit lichtempfindlichen Wirkstoffen |
TWI287455B (en) * | 2000-12-05 | 2007-10-01 | Noven Pharma | Crystallization inhibition of drugs in transdermal drug delivery systems and methods of use |
-
2004
- 2004-12-10 MX MXPA06006682A patent/MXPA06006682A/es active IP Right Grant
- 2004-12-10 BR BRPI0417530A patent/BRPI0417530B8/pt not_active IP Right Cessation
- 2004-12-10 KR KR1020067013923A patent/KR101168449B1/ko active IP Right Grant
- 2004-12-10 WO PCT/IB2004/052752 patent/WO2005058287A2/en active Application Filing
- 2004-12-10 EA EA200601089A patent/EA011160B1/ru not_active IP Right Cessation
- 2004-12-10 CN CN2004800413210A patent/CN1913878B/zh active Active
- 2004-12-10 AU AU2004298930A patent/AU2004298930B2/en not_active Ceased
- 2004-12-10 NZ NZ548091A patent/NZ548091A/en not_active IP Right Cessation
- 2004-12-10 JP JP2006543709A patent/JP4965263B2/ja active Active
- 2004-12-10 CA CA2549916A patent/CA2549916C/en not_active Expired - Fee Related
-
2006
- 2006-06-05 IL IL176112A patent/IL176112A/en active IP Right Grant
- 2006-06-06 NO NO20062594A patent/NO341989B1/no not_active IP Right Cessation
- 2006-07-11 ZA ZA2006/05713A patent/ZA200605713B/en unknown
- 2006-07-11 EC EC2006006694A patent/ECSP066694A/es unknown
-
2010
- 2010-07-05 CU CU20100143A patent/CU23868B1/es active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
BRPI0417530B1 (pt) | 2018-01-23 |
NO341989B1 (no) | 2018-03-12 |
CA2549916A1 (en) | 2005-06-30 |
AU2004298930B2 (en) | 2009-11-26 |
IL176112A0 (en) | 2006-10-05 |
IL176112A (en) | 2011-02-28 |
CU23868B1 (es) | 2013-03-27 |
CU20100143A7 (es) | 2011-10-31 |
CN1913878B (zh) | 2010-05-26 |
MXPA06006682A (es) | 2006-08-11 |
CN1913878A (zh) | 2007-02-14 |
NO20062594L (no) | 2006-07-10 |
JP4965263B2 (ja) | 2012-07-04 |
WO2005058287A3 (en) | 2006-03-02 |
WO2005058287A2 (en) | 2005-06-30 |
ZA200605713B (en) | 2008-01-08 |
CA2549916C (en) | 2013-09-17 |
AU2004298930A1 (en) | 2005-06-30 |
EA200601089A1 (ru) | 2006-12-29 |
BRPI0417530A (pt) | 2007-03-13 |
KR20060128910A (ko) | 2006-12-14 |
JP2007513938A (ja) | 2007-05-31 |
NZ548091A (en) | 2009-12-24 |
KR101168449B1 (ko) | 2012-07-25 |
BRPI0417530B8 (pt) | 2021-05-25 |
EA011160B1 (ru) | 2009-02-27 |
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