DE69918124D1 - Formulierungen zur transdermalen verabreichung von fenoldopam - Google Patents
Formulierungen zur transdermalen verabreichung von fenoldopamInfo
- Publication number
- DE69918124D1 DE69918124D1 DE69918124T DE69918124T DE69918124D1 DE 69918124 D1 DE69918124 D1 DE 69918124D1 DE 69918124 T DE69918124 T DE 69918124T DE 69918124 T DE69918124 T DE 69918124T DE 69918124 D1 DE69918124 D1 DE 69918124D1
- Authority
- DE
- Germany
- Prior art keywords
- fenoldopam
- transdermal administration
- formulations
- membrane
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- TVURRHSHRRELCG-UHFFFAOYSA-N fenoldopam Chemical compound C1=CC(O)=CC=C1C1C2=CC(O)=C(O)C(Cl)=C2CCNC1 TVURRHSHRRELCG-UHFFFAOYSA-N 0.000 title abstract 4
- 229960002724 fenoldopam Drugs 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- 239000012528 membrane Substances 0.000 abstract 2
- 238000012377 drug delivery Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003961 penetration enhancing agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9405998P | 1998-07-24 | 1998-07-24 | |
| PCT/US1999/016083 WO2000004886A1 (en) | 1998-07-24 | 1999-07-16 | Formulations for the transdermal administration of fenoldopam |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69918124D1 true DE69918124D1 (de) | 2004-07-22 |
| DE69918124T2 DE69918124T2 (de) | 2004-10-21 |
Family
ID=22242614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69918124T Expired - Fee Related DE69918124T2 (de) | 1998-07-24 | 1999-07-16 | Zusammensetzungen und Vorrichtungen zur transdermalen Verabreichung von Fenoldopam |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1100476B1 (de) |
| JP (1) | JP2002521324A (de) |
| AT (1) | ATE269063T1 (de) |
| AU (1) | AU5105699A (de) |
| DE (1) | DE69918124T2 (de) |
| ES (1) | ES2219037T3 (de) |
| PT (1) | PT1100476E (de) |
| WO (1) | WO2000004886A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11612607B2 (en) | 2016-08-31 | 2023-03-28 | Taro Pharmaceuticals Industries Ltd. | Fenoldopam topical formulations for treating skin disorders |
| JP7124234B2 (ja) * | 2019-03-08 | 2022-08-23 | タロー・ファーマシューティカル・インダストリーズ・リミテッド | フェノルドパムの安定な局所用組成物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4197297A (en) * | 1976-11-17 | 1980-04-08 | Smithkline Corporation | 6-Halo-7,8-dihydroxy-1-(hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepines |
| US5719197A (en) * | 1988-03-04 | 1998-02-17 | Noven Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| US5656286A (en) * | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| GB9009390D0 (en) * | 1990-04-26 | 1990-06-20 | Smith Kline French Lab | Pharmaceutical compositions |
| EP1021204B1 (de) * | 1997-09-26 | 2005-12-28 | Noven Pharmaceuticals, Inc. | Biologische kleber und verfahren zur topischen verabreichung von wirkstoffen |
-
1999
- 1999-07-16 ES ES99935613T patent/ES2219037T3/es not_active Expired - Lifetime
- 1999-07-16 DE DE69918124T patent/DE69918124T2/de not_active Expired - Fee Related
- 1999-07-16 JP JP2000560879A patent/JP2002521324A/ja active Pending
- 1999-07-16 PT PT99935613T patent/PT1100476E/pt unknown
- 1999-07-16 AT AT99935613T patent/ATE269063T1/de not_active IP Right Cessation
- 1999-07-16 EP EP99935613A patent/EP1100476B1/de not_active Expired - Lifetime
- 1999-07-16 WO PCT/US1999/016083 patent/WO2000004886A1/en not_active Ceased
- 1999-07-16 AU AU51056/99A patent/AU5105699A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1100476A1 (de) | 2001-05-23 |
| ATE269063T1 (de) | 2004-07-15 |
| AU5105699A (en) | 2000-02-14 |
| ES2219037T3 (es) | 2004-11-16 |
| EP1100476B1 (de) | 2004-06-16 |
| WO2000004886A1 (en) | 2000-02-03 |
| DE69918124T2 (de) | 2004-10-21 |
| PT1100476E (pt) | 2004-10-29 |
| JP2002521324A (ja) | 2002-07-16 |
| HK1036594A1 (en) | 2002-01-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |