CU20090169A7 - Métodos y composiciones para virus vivos atenuados - Google Patents
Métodos y composiciones para virus vivos atenuadosInfo
- Publication number
- CU20090169A7 CU20090169A7 CU20090169A CU20090169A CU20090169A7 CU 20090169 A7 CU20090169 A7 CU 20090169A7 CU 20090169 A CU20090169 A CU 20090169A CU 20090169 A CU20090169 A CU 20090169A CU 20090169 A7 CU20090169 A7 CU 20090169A7
- Authority
- CU
- Cuba
- Prior art keywords
- compositions
- live
- viruses
- methods
- attenuated
- Prior art date
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
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- C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
- C08L71/02—Polyalkylene oxides
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
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- A—HUMAN NECESSITIES
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- C08G2650/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G2650/28—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type
- C08G2650/58—Ethylene oxide or propylene oxide copolymers, e.g. pluronics
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- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10051—Methods of production or purification of viral material
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- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24151—Methods of production or purification of viral material
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- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24161—Methods of inactivation or attenuation
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- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16051—Methods of production or purification of viral material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16061—Methods of inactivation or attenuation
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- C—CHEMISTRY; METALLURGY
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
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- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24151—Methods of production or purification of viral material
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- C—CHEMISTRY; METALLURGY
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- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24161—Methods of inactivation or attenuation
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- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
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- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36161—Methods of inactivation or attenuation
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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Abstract
Las formas de realización de la presente se refieren a composiciones y métodos para virus vivos. En ciertas formas de realización, una composición a virus vivo atenuado incluye, sin limitaciones, uno o mas virus vivos atenuados y composiciones para reducir la inactivación y/o degradación del virus vivo atenuado. En otras formas de realización, la composición de virus vivo atenuado puede ser una composición de vacuna. En aún otras composiciones, una composición a virus vivo atenuado puede incluir al menos un hidrato de carbono, al menos una proteína y al menos un agente tensioactivo de alto peso molecular para reducir la inactivación y/o degradación del virus vivo atenuado.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US91057907P | 2007-04-06 | 2007-04-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
CU20090169A7 true CU20090169A7 (es) | 2012-06-21 |
Family
ID=39827288
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CU20090169A CU20090169A7 (es) | 2007-04-06 | 2009-10-06 | Métodos y composiciones para virus vivos atenuados |
Country Status (28)
Country | Link |
---|---|
US (4) | US8084039B2 (es) |
EP (2) | EP2144998B1 (es) |
JP (4) | JP5296775B2 (es) |
KR (4) | KR102134980B1 (es) |
CN (4) | CN101679954A (es) |
AU (1) | AU2008279576C1 (es) |
BR (1) | BRPI0809663B8 (es) |
CA (1) | CA2720570C (es) |
CO (1) | CO6260150A2 (es) |
CU (1) | CU20090169A7 (es) |
CY (1) | CY1118958T1 (es) |
DK (1) | DK2144998T3 (es) |
ES (1) | ES2621511T3 (es) |
HK (2) | HK1140516A1 (es) |
HR (1) | HRP20170513T1 (es) |
HU (1) | HUE031617T2 (es) |
IL (3) | IL201429A (es) |
LT (1) | LT2144998T (es) |
MX (2) | MX360728B (es) |
MY (2) | MY156422A (es) |
NZ (2) | NZ580978A (es) |
PH (1) | PH12015500773A1 (es) |
PL (1) | PL2144998T3 (es) |
PT (1) | PT2144998T (es) |
SG (2) | SG10201508397VA (es) |
SI (1) | SI2144998T1 (es) |
WO (1) | WO2009014774A1 (es) |
ZA (2) | ZA200907790B (es) |
Families Citing this family (46)
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KR102134980B1 (ko) * | 2007-04-06 | 2020-07-16 | 다케다 백신즈 인코포레이티드 | 살아있는 약독화된 바이러스를 위한 방법 및 조성물 |
EP2143440A1 (fr) * | 2008-07-09 | 2010-01-13 | Sanofi Pasteur | Agent stabilisant et composition vaccinale comprenant un ou plusieurs flavivirus vivants atténués |
US7998488B2 (en) | 2008-11-14 | 2011-08-16 | Baxter International Inc. | Vaccine formulations and uses thereof |
SG10201503671TA (en) * | 2008-12-05 | 2015-06-29 | Takeda Vaccines Inc | Compositions, methods and uses for inducing viral growth |
US9278070B2 (en) | 2009-05-18 | 2016-03-08 | Sigmoid Pharma Limited | Composition comprising oil drops |
EP2464341B1 (en) | 2009-08-12 | 2022-07-06 | Sublimity Therapeutics Limited | Immunomodulatory compositions comprising a polymer matrix and an oil phase |
DK2646052T3 (en) | 2010-12-02 | 2017-07-17 | Oncolytics Biotech Inc | LYOPHILIZED VIRAL FORMULATIONS |
TW201233802A (en) | 2010-12-02 | 2012-08-16 | Oncolytics Biotech Inc | Liquid viral formulations |
RU2013143149A (ru) * | 2011-02-24 | 2015-03-27 | Пэксвэкс, Инк. | Составы, пригодные для вакцин, получаемых сушкой распылением |
KR20140033171A (ko) * | 2011-05-26 | 2014-03-17 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 비활성화된 뎅기 바이러스 백신 |
JP6417217B2 (ja) * | 2011-06-28 | 2018-10-31 | ロイコケア・アクチェンゲゼルシャフト | ウイルスまたは細菌の新規な安定化方法 |
EP3246400B1 (en) | 2012-01-09 | 2019-10-23 | Sanofi Pasteur Biologics, LLC | Purification of herpes virus |
WO2013177172A2 (en) * | 2012-05-21 | 2013-11-28 | Sanofi Pasteur Limited | Herpesvirus compositions and related methods |
GB201212010D0 (en) | 2012-07-05 | 2012-08-22 | Sigmoid Pharma Ltd | Formulations |
US9314519B2 (en) * | 2012-08-21 | 2016-04-19 | Intervet Inc. | Liquid stable virus vaccines |
EP2968515B1 (en) | 2013-03-14 | 2019-05-08 | Takeda Vaccines, Inc. | Compositions and methods for live, attenuated alphavirus formulations |
US9480739B2 (en) | 2013-03-15 | 2016-11-01 | Intervet Inc. | Bovine virus vaccines that are liquid stable |
US9393298B2 (en) | 2013-03-15 | 2016-07-19 | Intervet Inc. | Liquid stable bovine virus vaccines |
AR097762A1 (es) | 2013-09-27 | 2016-04-13 | Intervet Int Bv | Formulaciones secas de vacunas que son estables a temperatura ambiente |
US10588957B2 (en) | 2013-10-25 | 2020-03-17 | Leukocare Ag | Method for the production of stabile vaccines |
GB201319791D0 (en) | 2013-11-08 | 2013-12-25 | Sigmoid Pharma Ltd | Formulations |
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